scholarly journals Third Dose of the BNT162b2 Vaccine Results in Very High Levels of Neutralizing Antibodies Against SARS‐CoV ‐2; Results of a Prospective Study in 150 Health Professionals in Greece

Author(s):  
Evangelos Terpos ◽  
Vangelis Karalis ◽  
Aimilia D. Sklirou ◽  
Filia Apostolakou ◽  
Ioannis Ntanasis‐Stathopoulos ◽  
...  
2021 ◽  
Vol 5 (1) ◽  
pp. e000966
Author(s):  
Jhon Camacho-Cruz ◽  
Shirley Briñez ◽  
Jorge Alvarez ◽  
Victoria Leal ◽  
Licet Villamizar Gómez ◽  
...  

IntroductionMost scales for acute respiratory infection (ARI) are limited to healthcare worker (HCW) use for clinical decision-making. The Respiratory Syncytial Virus network (ReSVinet) Scale offers a version for parents that could potentially help as an early warning system.ObjectiveTo determine whether or not the ReSVinet Scale for ARI in infants can be reliably used by HCWs and parents in an emergency service.MethodsA prospective study was done of infants with ARI who were admitted to a paediatric emergency room to assess the ReSVinet Scale when used by faculty (paediatric doctor-professors), residents (doctors doing their first specialty in paediatrics) and parents. Spearman’s correlation and a weighted kappa coefficient were used to measure interobserver agreement. Internal consistency was also tested by Cronbach’s alpha test.ResultsOverall, 188 patients, 58% male, were enrolled. A Spearman’s correlation of 0.92 for faculty and resident scoring and 0.64 for faculty or resident and parent scoring was found. The weighted kappa coefficients were 0.78 for faculty versus residents, 0.41 for faculty versus parents, and 0.41 for residents versus parents. Cronbach’s alpha test was 0.67 for faculty, 0.62 for residents and 0.69 for parents.ConclusionThere was good correlation in the ReSVinet scores between health professionals when used in the paediatric emergency area. Agreement between parents and health professionals was found to be more variable. Future studies should focus on finding ways to improve its reliability when used by parents before the scale is used in the emergency room.


2021 ◽  
Vol 200 ◽  
pp. S22
Author(s):  
J. Liz Pimenta ◽  
K. Ladeira ◽  
A. Teira ◽  
M. Rocha ◽  
P. Gago ◽  
...  

2014 ◽  
Vol 5 (2) ◽  
pp. e49 ◽  
Author(s):  
Matthew R Boylan ◽  
Hamed Khalili ◽  
Edward S Huang ◽  
Dominique S Michaud ◽  
Jacques Izard ◽  
...  

2020 ◽  
Vol 14 (12) ◽  
pp. e0008887
Author(s):  
Li Jun Thean ◽  
Adam Jenney ◽  
Daniel Engelman ◽  
Lucia Romani ◽  
Handan Wand ◽  
...  

Scabies is an important predisposing factor for impetigo but its role in more serious skin and soft tissue infections (SSTIs) is not well understood. Information is limited on incidence of SSTIs in the presence of endemic scabies. We conducted a prospective study of hospital admissions for SSTIs in the Northern Division of Fiji (population: 131,914). Prospective surveillance for admissions with impetigo, abscess, cellulitis, wound infection, pyomyositis, necrotizing fasciitis, infected scabies, and crusted scabies was conducted at the Division’s referral hospital between 2018 to 2019. Information was collected on demographic characteristics, clinical features, microbiology, treatment and outcomes. Over the study period, 788 SSTI admissions were recorded corresponding to a population incidence 647 per 100,000 person-years (95%CI 571–660). Incidence was highest at the extremes of age with peak incidence in children aged <5 years (908 per 100,000) and those aged ≥65 years (1127 per 100,000). Incidence was 1.7 times higher among the Indigenous Fijian population (753 per 100,000) compared to other ethnicities (442 per 100,000). Overall case fatality rate was 3.3%, and 10.8% for those aged ≥65 years. Scabies was diagnosed concurrently in 7.6% of all patients and in 24.6% of admitted children <5 years. There is a very high burden of hospital admissions for SSTIs in Fiji compared to high-income settings especially among the youngest, oldest and indigenous population which is concordant with scabies and impetigo distribution in this population. Our findings highlight the need for strategies to reduce the burden of SSTIs in Fiji and similar settings.


2021 ◽  
Vol 11 (6) ◽  
pp. 695
Author(s):  
Liviu Cozma ◽  
Mioara Avasilichioaei ◽  
Natalia Dima ◽  
Bogdan Ovidiu Popescu

Diagnosing atypical parkinsonism can be an error-exposed undertaking in the context of elaborate criteria coupled with time restraints on their comprehensive application. We conducted a retrospective, descriptive study of diagnostic accuracy among physicians at two tertiary neurology centers in Romania and developed an algorithmic tool for comparison purposes. As many as 90 patients qualified for inclusion in the study, with 77 patients actually complying with atypical parkinsonism criteria. Overall, physician-established diagnoses may be incorrect in about one-fourth of cases. The reasons for this finding span a wide range of possibilities, from terminology-related inaccuracies to criteria sophistication. A Boolean-logic algorithmic approach to diagnosis might decrease misdiagnosis rates. These findings prepare the ground for the future refinement of an algorithmic application to be fully validated in a prospective study for the benefit of patients and health professionals alike.


2007 ◽  
Vol 99 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Dominique S. Michaud ◽  
Kaumudi Joshipura ◽  
Edward Giovannucci ◽  
Charles S. Fuchs

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