Surgically treated gastric cancer in Japan: 2011 annual report of the national clinical database gastric cancer registry

Abstracts Background The number of elderly patients with gastric cancer has been increasing. Most elderly patients have associated reduced physiologic functions that can sometimes become an obstacle to safe surgical treatment. The National Clinical Database Risk Calculator, which based on a large Japanese surgical database, provides predicted mortality and morbidity in each case as the surgical-related risks. The purpose of this study was to investigate the clinical significance of the risk for operative mortality (NRC-mortality), as calculated by the National Clinical Database Risk Calculator, during long-term follow-up after gastrectomy for elderly patients with gastric cancer. Methods We enrolled 73 patients aged ≥ 80 years and underwent gastrectomy at our institution. Their surgical risk was evaluated based on the NRC-mortality. Several clinicopathologic factors, including NRC-mortality, were selected and analyzed as the possible prognostic factors for elderly patients who have undergone gastrectomy for gastric cancer. Statistical analysis was performed using the log-rank test and Cox proportional hazard model. Results NRC-mortality ranged from 0.5 to 10.6%, and the median value was 1.7%. Dividing the patients according to mortality, the overall survival was significantly worse in the high mortality group (≥ 1.7%, n = 38) than in the low mortality group (< 1.7%, n = 35), whereas disease-specific survival was not different between the two groups. In the Cox proportional hazard model, multivariate analysis revealed NRC-mortality, performance status, and surgical procedure as the independent prognostic factors for overall survival. For disease-specific survival, the independent prognostic factors were performance status and pathological stage but not NRC-mortality. Conclusion The NRC-mortality might be clinically useful for predicting both surgical mortality and overall survival after gastrectomy in elderly patients with gastric cancer.

Download Full-text

Annual Report of National Clinical Database in Gastroenterological Surgery 2011–2012

The Japanese Journal of Gastroenterological Surgery ◽

10.5833/jjgs.2013.sr001 ◽

2013 ◽

Vol 46 (12) ◽

pp. 952-963 ◽

Cited By ~ 11

Author(s):

Hiroyuki Konno ◽

Go Wakabayashi ◽

Harushi Udagawa ◽

Michiaki Unno ◽

Chikara Kunisaki ◽

...

Keyword(s):

Annual Report ◽

Clinical Database ◽

National Clinical Database

Download Full-text

Annual Report of National Clinical Database in Gastroenterological Surgery 2015

The Japanese Journal of Gastroenterological Surgery ◽

10.5833/jjgs.2017.sr001 ◽

2017 ◽

Vol 50 (2) ◽

pp. 166-176 ◽

Cited By ~ 1

Author(s):

Yoshihiro Kakeji ◽

Harushi Udagawa ◽

Michiaki Unno ◽

Itaru Endo ◽

Chikara Kunisaki ◽

...

Keyword(s):

Annual Report ◽

Clinical Database ◽

National Clinical Database

Download Full-text

Japan Pancreatic Cancer Registry of Japan Pancreas Society: Comparison between the conventional database and National Clinical Database (NCD)

Pancreatology ◽

10.1016/j.pan.2016.06.322 ◽

2016 ◽

Vol 16 (4) ◽

pp. S90 ◽

Cited By ~ 1

Author(s):

Masamichi Mizuma ◽

Michiaki Unno ◽

Hisato Igarashi ◽

Takao Itoi ◽

Shinichi Egawa ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Registry ◽

Clinical Database ◽

National Clinical Database

Download Full-text

Mortality calculator as a possible prognostic predictor of overall survival after gastrectomy in elderly patients with gastric cancer

10.21203/rs.3.rs-58126/v1 ◽

2020 ◽

Author(s):

Hidenori Akaike ◽

Yoshihiko Kawaguchi ◽

Suguru Maruyama ◽

Katsutoshi Shoda ◽

Ryo Satio ◽

...

Keyword(s):

Gastric Cancer ◽

Overall Survival ◽

Prognostic Factors ◽

Elderly Patients ◽

Performance Status ◽

Proportional Hazard ◽

Proportional Hazard Model ◽

Clinical Database ◽

National Clinical Database ◽

Cox Proportional Hazard

Abstract Background: The number of elderly patients with gastric cancer has been increasing. Most elderly patients have associated reduced physiologic functions, that can sometimes become an obstacle to safe surgical treatment. The National Clinical Database Risk Calculator, which based on a large Japanese surgical database, provides mortality and morbidity as the surgical-related risks. The purpose of this study was to investigate the clinical significance of the risk for operative mortality (NRC-mortality), as calculated by the National Clinical Database Risk Calculator, during long-term follow-up after gastrectomy for elderly patients with gastric cancer.Methods: We enrolled 73 patients aged ≥80 years and underwent gastrectomy at our institution. Their surgical risk was evaluated based on the NRC-mortality. Several clinicopathologic factors, including NRC-mortality, were selected, and analyzed as the possible prognostic factors for elderly patients who have undergone gastrectomy for gastric cancer. Statistical analysis was performed using the log-rank test and Cox proportional hazard model.Results: NRC-mortality ranged from 0.5% to 10.6%, and the median value was 1.7%. Dividing the patients according to mortality, the overall survival was significantly worse in the high mortality group (≥1.7%, n = 38) than in the low mortality group (<1.7%, n = 35), whereas disease-specific survival was not different between the two groups. In the Cox proportional hazard model, multivariate analysis revealed NRC-mortality, performance status, and surgical procedure as the independent prognostic factors for overall survival. For disease-specific survival, the independent prognostic factors were performance status and pathological stage but not NRC-mortality.Conclusion: The NRC-mortality might be clinically useful for predicting both surgical mortality and overall survival after gastrectomy in elderly patients with gastric cancer.

Download Full-text

Mortality calculator as a possible prognostic predictor of overall survival after gastrectomy in elderly patients with gastric cancer

10.21203/rs.3.rs-58126/v2 ◽

2020 ◽

Author(s):

Hidenori Akaike ◽

Yoshihiko Kawaguchi ◽

Suguru Maruyama ◽

Katsutoshi Shoda ◽

Ryo Satio ◽

...

Keyword(s):

Gastric Cancer ◽

Overall Survival ◽

Prognostic Factors ◽

Elderly Patients ◽

Performance Status ◽

Proportional Hazard ◽

Proportional Hazard Model ◽

Clinical Database ◽

National Clinical Database ◽

Cox Proportional Hazard

Abstract Background: The number of elderly patients with gastric cancer has been increasing. Most elderly patients have associated reduced physiologic functions, that can sometimes become an obstacle to safe surgical treatment. The National Clinical Database Risk Calculator, which based on a large Japanese surgical database, provides predicted mortality and morbidity in each case as the surgical-related risks. The purpose of this study was to investigate the clinical significance of the risk for operative mortality (NRC-mortality), as calculated by the National Clinical Database Risk Calculator, during long-term follow-up after gastrectomy for elderly patients with gastric cancer.Methods: We enrolled 73 patients aged ≥80 years and underwent gastrectomy at our institution. Their surgical risk was evaluated based on the NRC-mortality. Several clinicopathologic factors, including NRC-mortality, were selected, and analyzed as the possible prognostic factors for elderly patients who have undergone gastrectomy for gastric cancer. Statistical analysis was performed using the log-rank test and Cox proportional hazard model.Results: NRC-mortality ranged from 0.5% to 10.6%, and the median value was 1.7%. Dividing the patients according to mortality, the overall survival was significantly worse in the high mortality group (≥1.7%, n = 38) than in the low mortality group (<1.7%, n = 35), whereas disease-specific survival was not different between the two groups. In the Cox proportional hazard model, multivariate analysis revealed NRC-mortality, performance status, and surgical procedure as the independent prognostic factors for overall survival. For disease-specific survival, the independent prognostic factors were performance status and pathological stage but not NRC-mortality.Conclusion: The NRC-mortality might be clinically useful for predicting both surgical mortality and overall survival after gastrectomy in elderly patients with gastric cancer.

Download Full-text