scholarly journals A phenomenological investigation of patients’ experiences during direct observation in residency: busting the myth of the fly on the wall

2021 ◽  
Author(s):  
Chris B. T. Rietmeijer ◽  
Mark Deves ◽  
Suzanne C. M. van Esch ◽  
Henriëtte E. van der Horst ◽  
Annette H. Blankenstein ◽  
...  
Keyword(s):  
Direct Observation ◽  
Postgraduate Medical Education ◽  
Essential Elements ◽  
Educational Tool ◽  
Final Phase ◽  
Complete Understanding ◽  
Benefit Patient ◽  
New Perspective ◽  
Phenomenological Interview

AbstractDirect observation (DO) of residents by supervisors is a highly recommended educational tool in postgraduate medical education, yet its uptake is poor. Residents and supervisors report various reasons for not engaging in DO. Some of these relate to their interaction with patients during DO. We do not know the patient perspectives on these interactions, nor, more broadly, what it is like to be a patient in a DO situation. Understanding the patient perspective may lead to a more complete understanding of the dynamics in DO situations, which may benefit patient wellbeing and improve the use of DO as an educational tool. We conducted a phenomenological interview study to investigate the experience of being a patient in a DO situation. Our analysis included multiple rounds of coding and identifying themes, and a final phase of phenomenological reduction to arrive at the essential elements of the experience. Constant reflexivity was at the heart of this process. Our results provide a new perspective on the role of the supervisor in DO situations. Patients were willing to address the resident, but sought moments of contact with, and some participation by, the supervisor. Consequently, conceptions of DO in which the supervisor thinks she is a fly on the wall rather than a part of the interaction, should be critically reviewed. To that end, we propose the concept of participative direct observation in workplace learning, which also acknowledges the observer’s role as participant. Embracing this concept may benefit both patients’ wellbeing and residents’ learning.

Is a snake scarier than a gun? The ontogenetic–phylogenetic dispute from a new perspective: The role of arousal.

Emotion ◽  
2019 ◽  
Vol 19 (4) ◽  
pp. 726-732 ◽  
Author(s):  
Andras Norbert Zsido ◽  
Anita Deak ◽  
Laszlo Bernath
Keyword(s):  
New Perspective

Problem of Confidence and its Loss – the Role of a Family in Instilling Truthfulness

2014 ◽  
Vol 4 (2) ◽  
pp. 15-22
Author(s):  
Grzegorz Ignatowski
Keyword(s):  
Close Relationships ◽  
Essential Elements ◽  
Professional Group ◽  
Professional Life ◽  
Personal Life

Abstract Confidence is one of the most essential elements which no social or professional group can exist without. As feature of character it is required in someone’s private, social and professional life. In all our relationships we lose it due to telling lies. Lies accompany our personal life on all its stages. Already three-year old children tell lies to satisfy their parents, check whether they are able to realize they are deceived or to demonstrate their dominance over them. Teachers and ethicists differentiate between useful didactic lies and ruthless and cynical comments harmful to others. Because of emotional ties and close relationships, a family is the best environment where a child should be taught to despise lies and respect trust

Epilogue

2018 ◽  
Author(s):  
Bruno and
Keyword(s):  
Sensory Processing ◽  
Multisensory Processing ◽  
Multisensory Perception ◽  
Future Directions ◽  
Life Problems ◽  
Multisensory Interactions ◽  
Contemporary Work ◽  
New Perspective

Multisensory interactions in perception are pervasive and fundamental, as we have documented throughout this book. In this final chapter, we propose that contemporary work on multisensory processing is a paradigm shift in perception science, calling for a radical reconsideration of empirical and theoretical questions within an entirely new perspective. In making our case, we emphasize that multisensory perception is the norm, not the exception, and we remark that multisensory interactions can occur early in sensory processing. We reiterate the key notions that multisensory interactions come in different kinds and that principles of multisensory processing must be considered when tackling multisensory daily-life problems. We discuss the role of unisensory processing in a multisensory world, and we conclude by suggesting future directions for the multisensory field.

Shifting Concepts

2020 ◽  
Keyword(s):  
Experimental Philosophy ◽  
Central Area ◽  
Linguistic Meaning ◽  
Human Cognition ◽  
Important Work ◽  
Linguistic Communication ◽  
New Perspective ◽  
Semantic Properties ◽  
Conceptual Variation

Concepts stand at the centre of human cognition. We use concepts in categorizing objects and events in the world, in reasoning and action, and in social interaction. It is therefore not surprising that the study of concepts constitutes a central area of research in philosophy and psychology. Since the 1970s, psychologists have carried out intriguing experiments testing the role of concepts in categorizing and reasoning, and have found a great deal of variation in categorization behaviour across individuals and cultures. During the same period, philosophers of language and mind did important work on the semantic properties of concepts, and on how concepts are related to linguistic meaning and linguistic communication. An important motivation behind this was the idea that concepts must be shared, across individuals and cultures. However, there was little interaction between these two research programs until recently. With the dawn of experimental philosophy, the proposal that the experimental data from psychology lacks relevance to semantics is increasingly difficult to defend. Moreover, in the last decade, philosophers have approached questions about the tension between conceptual variation and shared concepts in communication from a new perspective: that of ameliorating concepts for theoretical or for social and political purposes. The volume brings together leading psychologists and philosophers working on concepts who come from these different research traditions.

Proposal for an IMF Debt Refinancing Subsidiary

2018 ◽  
Keyword(s):  
Developing Country ◽  
Essential Elements ◽  
Acceptable Solution ◽  
Debt Problem ◽  
The Imf

In the chapter, Haq analyses the deepening developing country debt problem of the 1980s and outlines the essential elements for an acceptable solution to the problem. To Haq, IMF seemed to be the most appropriate international intermediary to manage this. Haq goes on to outline the specifics of how the role of the IMF could be modified to find long-term solutions for managing developing-country debt.

scholarly journals Exosomes: a new perspective in EGFR-mutated lung cancer

2021 ◽  
Author(s):  
Amina Jouida ◽  
Cormac McCarthy ◽  
Aurelie Fabre ◽  
Michael P. Keane
Keyword(s):  
Lung Cancer ◽  
Cell Communication ◽  
Egfr Mutations ◽  
Functional Effect ◽  
Prognosis And Prediction ◽  
Novel Biomarkers ◽  
New Perspective ◽  
Source Of Information ◽  
Egfr Mutated

AbstractExosomes are major contributors in cell to cell communication due to their ability to transfer biological material such as protein, RNA, DNA, and miRNA. Additionally, they play a role in tumor initiation, promotion, and progression, and recently, they have emerged as a potential source of information on tumor detection and may be useful as diagnostic, prognostic, and predictive tools. This review focuses on exosomes from lung cancer with a focus on EGFR mutations. Here, we outline the role of exosomes and their functional effect in carcinogenesis, tumor progression, and metastasis. Finally, we discuss the possibility of exosomes as novel biomarkers in early detection, diagnosis, assessment of prognosis, and prediction of therapeutic response in EGFR-mutated lung cancer.

GINS: A Global intensifier-based N-Gram sentiment dictionary

2021 ◽  
pp. 1-14
Author(s):  
Hamed Zargari ◽  
Morteza Zahedi ◽  
Marziea Rahimi
Keyword(s):  
Sentiment Analysis ◽  
Essential Elements ◽  
Analysis Methods ◽  
Sentiment Dictionary ◽  
N Gram ◽  
Heterogeneous Effect ◽  
Sentiment Word

Words are one of the most essential elements of expressing sentiments in context although they are not the only ones. Also, syntactic relationships between words, morphology, punctuation, and linguistic phenomena are influential. Merely considering the concept of words as isolated phenomena causes a lot of mistakes in sentiment analysis systems. So far, a large amount of research has been conducted on generating sentiment dictionaries containing only sentiment words. A number of these dictionaries have addressed the role of combinations of sentiment words, negators, and intensifiers, while almost none of them considered the heterogeneous effect of the occurrence of multiple linguistic phenomena in sentiment compounds. Regarding the weaknesses of the existing sentiment dictionaries, in addressing the heterogeneous effect of the occurrence of multiple intensifiers, this research presents a sentiment dictionary based on the analysis of sentiment compounds including sentiment words, negators, and intensifiers by considering the multiple intensifiers relative to the sentiment word and assigning a location-based coefficient to the intensifier, which increases the covered sentiment phrase in the dictionary, and enhanced efficiency of proposed dictionary-based sentiment analysis methods up to 7% compared to the latest methods.

scholarly journals From Exosome Glycobiology to Exosome Glycotechnology, the Role of Natural Occurring Polysaccharides

2021 ◽  
Vol 2 (2) ◽  
pp. 311-338
Author(s):  
Giulia Della Rosa ◽  
Clarissa Ruggeri ◽  
Alessandra Aloisi
Keyword(s):  
State Of The Art ◽  
Cell Communication ◽  
Pathological Conditions ◽  
New Findings ◽  
Cell Type Specific ◽  
New Perspective ◽  
And Function ◽  
And Personalized Medicine ◽  
Innate Ability

Exosomes (EXOs) are nano-sized informative shuttles acting as endogenous mediators of cell-to-cell communication. Their innate ability to target specific cells and deliver functional cargo is recently claimed as a promising theranostic strategy. The glycan profile, actively involved in the EXO biogenesis, release, sorting and function, is highly cell type-specific and frequently altered in pathological conditions. Therefore, the modulation of EXO glyco-composition has recently been considered an attractive tool in the design of novel therapeutics. In addition to the available approaches involving conventional glyco-engineering, soft technology is becoming more and more attractive for better exploiting EXO glycan tasks and optimizing EXO delivery platforms. This review, first, explores the main functions of EXO glycans and associates the potential implications of the reported new findings across the nanomedicine applications. The state-of-the-art of the last decade concerning the role of natural polysaccharides—as targeting molecules and in 3D soft structure manufacture matrices—is then analysed and highlighted, as an advancing EXO biofunction toolkit. The promising results, integrating the biopolymers area to the EXO-based bio-nanofabrication and bio-nanotechnology field, lay the foundation for further investigation and offer a new perspective in drug delivery and personalized medicine progress.

scholarly journals Benefits of EPAs at risk? The influence of the workplace environment on the uptake of EPAs in EPA-based curricula

2021 ◽  
Author(s):  
Karsten Arthur van Loon ◽  
Linda Helena Anna Bonnie ◽  
Nynke van Dijk ◽  
Fedde Scheele
Keyword(s):  
At Risk ◽  
Postgraduate Medical Education ◽  
Training Programme ◽  
Workplace Environment ◽  
Medical Specialists ◽  
Professional Activities ◽  
National Training ◽  
Local Medical Care

Abstract Introduction Entrustable Professional Activities (EPAs) have been applied differently in many postgraduate medical education (PGME) programmes, but the reasons for and the consequences of this variation are not well known. Our objective was to investigate how the uptake of EPAs is influenced by the workplace environment and to what extent the benefits of working with EPAs are at risk when the uptake of EPAs is influenced. This knowledge can be used by curriculum developers who intend to apply EPAs in their curricula. Method For this qualitative study, we selected four PGME programmes: General Practice, Clinical Geriatrics, Obstetrics & Gynaecology, and Radiology & Nuclear Medicine. A document analysis was performed on the national training plans, supported by the AMEE Guide for developing EPA-based curricula and relevant EPA-based literature. Interviews were undertaken with medical specialists who had specific involvement in the development of the curricula. Content analysis was employed and illuminated the possible reasons for variation in the uptake of EPAs. Results An important part of the variation in the uptake of EPAs can be explained by environmental factors, such as patient population, the role of the physician in the health-care system, and the setup of local medical care institutions where the training programme takes place. The variation in uptake of EPAs is specifically reflected in the number and breadth of the EPAs, and in the way the entrustment decision is executed within the PGME programme. Discussion Due to variation in uptake of EPAs, the opportunities for trainees to work independently during the training programme might be challenging. EPAs can be implemented in the curriculum of PGME programmes in a meaningful way, but only if the quality of an EPA is assessed, future users are involved in the development, and the key feature of EPAs (the entrustment decision) is retained.

scholarly journals Regulation of miRNAs by Natural Antioxidants in Cardiovascular Diseases: Focus on SIRT1 and eNOS

Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 377
Author(s):  
Yunna Lee ◽  
Eunok Im
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Diseases ◽  
Endothelial Dysfunction ◽  
Natural Antioxidants ◽  
Sirtuin 1 ◽  
Potential Benefits ◽  
New Perspective ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Cardiovascular diseases (CVDs) are the most common cause of morbidity and mortality worldwide. The potential benefits of natural antioxidants derived from supplemental nutrients against CVDs are well known. Remarkably, natural antioxidants exert cardioprotective effects by reducing oxidative stress, increasing vasodilation, and normalizing endothelial dysfunction. Recently, considerable evidence has highlighted an important role played by the synergistic interaction between endothelial nitric oxide synthase (eNOS) and sirtuin 1 (SIRT1) in the maintenance of endothelial function. To provide a new perspective on the role of natural antioxidants against CVDs, we focused on microRNAs (miRNAs), which are important posttranscriptional modulators in human diseases. Several miRNAs are regulated via the consumption of natural antioxidants and are related to the regulation of oxidative stress by targeting eNOS and/or SIRT1. In this review, we have discussed the specific molecular regulation of eNOS/SIRT1-related endothelial dysfunction and its contribution to CVD pathologies; furthermore, we selected nine different miRNAs that target the expression of eNOS and SIRT1 in CVDs. Additionally, we have summarized the alteration of miRNA expression and regulation of activities of miRNA through natural antioxidant consumption.

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