In vitro free radical scavenging activity of ethanolic extract of the whole plant of Evolvulus alsinoides (L.) L.

2014 ◽  
Vol 21 (6) ◽  
pp. 453-458 ◽  
Author(s):  
Duraisamy Gomathi ◽  
Ganesan Ravikumar ◽  
Manokaran Kalaiselvi ◽  
Balasubramaniam Vidya ◽  
Chandrasekar Uma
2012 ◽  
Vol 02 (04) ◽  
pp. 02-07
Author(s):  
Bhagya Bhaskar ◽  
Ramakrishna Avadhani

AbstractIn vitro free radical scavenging activity of aqueous and ethanolic bark extracts of Bauhinia racemosa was assessed by studying its ability to scavenge DPPH, Nitric oxide, hydroxyl radical and reducing power. Both the extracts showed effective free radical scavenging activity. Ethanolic extract was comparatively more potential than aqueous extract. The results support its traditional use in various ailments and as a source of natural antioxidants which protect cells against oxidative stress.


Author(s):  
Md Raihan Sarkar ◽  
Moynul Hasan ◽  
Md Sariful Islam Howlader ◽  
Mohammad Saydur Rahman ◽  
Shubhra Kanti Dey

In the present study, the antioxidant and analgesic potential of the ethanolic extract of the leaves of Derris trifoliata was evaluated. The free radical scavenging activity of the crude extract on the stable radical 1, 1-diphenyl-2-picrylhydrazyl (DPPH) was determined by comparing the DPPH inhibitory capacity of the extract. In the quantitative assay, Derris trifoliata extract displayed a free radical scavenging activity in the DPPH assay (IC50 = 19 ?g/ml) which is comparable to that of ascorbic acid (IC50 = 7.80 ?g/ml), a well-known standard antioxidant. The analgesic responses of the given samples of extracts were evaluated using the Tail immersion method. In the analgesic activity test, extract at dose of 200 mg/kg and 400 mg/kg exhibited significant (P<0.05 and P<0.001 respectively) inhibition of pain by 166.82 and 184.95 after 120 and 180 minutes respectively while the standard drug Diclofenac Na inhibition was found to be 217.67 after 180 minutes at a dose of 25 mg/kg body weight DOI: http://dx.doi.org/10.3329/ijpls.v1i2.12951 International Journal of Pharmaceutical and Life Sciences Vol.1(2) 2012


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