scholarly journals Can the Japanese National Clinical Database risk calculator predict long-term survival of patients who undergo palliative segmentectomy for primary lung cancer?

2021 ◽  
Author(s):  
Tomoyuki Nakano ◽  
Hiroyoshi Tsubochi ◽  
Mitsuru Maki ◽  
Kentaro Minegishi ◽  
Tomoki Shibano ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Thoracoscopic Surgery ◽  
Primary Lung Cancer ◽  
Risk Calculator ◽  
Clinical Database ◽  
National Clinical Database ◽  
Term Survival ◽  
Limited Surgery ◽  
Long Term Prognosis

Abstract Objectives Selection criteria for palliative limited surgery in patients with non-small cell lung cancer (NSCLC) can vary by institution or surgeon. We retrospectively reviewed outcomes of poor-risk patients who underwent palliative segmentectomy (PS), using the National Clinical Database Risk Calculator (RC). Methods We retrospectively analyzed medical records of patients with NSCLC tumors ≥ 20 mm and consolidation/tumor ratios ≥ 0.5 on computed tomography, who underwent PS from January 2009 to March 2016. Median follow-up time was 47 months (range 2–102 months). Results We enrolled 67 patients (median age: 73.0 years), of whom 54 received thoracoscopic surgery and 28 received medial lymph-node dissection. The RC’s mean predictive probability rate for perioperative mortality or severe complications was 7.1%. Of the 67 patients, 24 patients (43.0%) suffered post-surgical complications, including 2 (3%) who died in hospital; 17 eventually suffered NSCLC recurrences and/or metastases, 11 eventually died from NSCLC, and 17 died from other diseases. Five-year overall survival (OS) was 59.4%. When the patients were divided into high-risk (HR) and low-risk (LR) groups based on the RC, 5-year OS was significantly less in the HR group (43.9%) than in the LR group (82.2%; P < 0.05). Conclusion The RC, which was developed primarily to determine perioperative risk, can predict long-term prognosis for compromised patients who undergo PS.

scholarly journals Preoperative virtual simulation for synchronous multiple primary lung cancers using three-dimensional computed tomography lung reconstruction: a case report

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Weichun Wu ◽  
Yimin Wu ◽  
Gang Shen ◽  
Guofei Zhang
Keyword(s):  
Computed Tomography ◽  
Thoracoscopic Surgery ◽  
Three Dimensional ◽  
Primary Lung Cancer ◽  
Pulmonary Nodules ◽  
Term Survival ◽  
Lung Cancers ◽  
Multiple Primary ◽  
Feasible Alternative

Abstract Background As the positions and sizes of nodules in synchronous multiple primary lung cancer (SMPLC) patients differ, the development of surgical strategies to maximize long-term survival and preserved postoperative pulmonary function in SMPLC patients for whom surgical resection is an alternative strategy presents challenges. Case presentation We provide a case managed through video-assisted thoracoscopic surgery (VATS) resection using three-dimensional computed tomography lung reconstruction (3D-CTLR) to reconstruct lobes containing pulmonary nodules to preoperatively simulate and intraoperatively guide the extent and method of resection. Conclusion The successful attempt demonstrates a technically simplified, feasible alternative to preoperative plans utilizing less invasive VATS to manage SMPLC.

scholarly journals Factors in long term survival (more than 10 years) after resection of primary lung cancer.

1996 ◽  
Vol 10 (1) ◽  
pp. 31-38
Author(s):  
Toshihiko Iizasa ◽  
Yutaka Yamaguchi ◽  
Masayuki Baba ◽  
Mitutoshi Shiba
Keyword(s):  
Lung Cancer ◽  
Primary Lung Cancer ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Long-term prognosis of video-assisted limited surgery for early lung cancer☆

2009 ◽  
Author(s):  
Kazuro Sugi ◽  
Seiki Kobayashi ◽  
Manabu Sudou ◽  
Hisashi Sakano ◽  
Eisuke Matsuda ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Video Assisted ◽  
Early Lung Cancer ◽  
Limited Surgery ◽  
Long Term Prognosis

scholarly journals The Diameter of Bronchial Resection Margin is Associated With Postoperative Lung Metastasis and Long-term Survival

2020 ◽  
Author(s):  
Zengtuan Xiao ◽  
Mengzhe Zhang ◽  
Xiaofei Wang ◽  
Jialin Gong ◽  
Zuo Liu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Risk Factor ◽  
Lung Metastasis ◽  
Independent Risk Factor ◽  
Resection Margin ◽  
Primary Lung Cancer ◽  
Term Survival ◽  
Long Term Survival ◽  
Bronchial Resection

Abstract BackgroundTo investigate the significance of the diameter of bronchial resection margin (DBRM) on the postoperative lung metastasis and long -term survival of patients with primary lung cancer.MethodsWe retrospectively analyzed the data of 1844 patients with primary lung cancer between January 2006 and December 2010 after surgery. Patients were divided into DBRM≤1 cm group (826 patients) and DBRM>1 cm group (1018 patients). Propensity score matching was used to reduce grouping selection bias. Furthermore, we divide the 974 patients who had definite first metastasis site into lung metastasis group (283 patients) and other metastasis group (691 patients), and analyzed related risk factors and prognosis of metastasis. Disease-free survival and overall survival were the study end points.ResultsThe DBRM≤1 cm group had a significantly better prognosis than DBTM>1 cm group (5-year DFS, 36.5% vs 25.7%; P < 0.001; 5-year OS, 45.4% vs 34.1%; P < 0.001). After multivariate survival analysis, DBRM remained the independent favorable effect on DFS (HR, 1.198; 95% CI, 1,071 to 1.340; P = 0.002) and OS (HR, 1.186; 95% CI, 1.060 to1.327; P = 0.003). PSM further confirmed that DBRM≤1 cm group had a better DFS (P = 0.032) and OS (P = 0.026) than the DBRM>1 cm group. It revealed that the DBRM was an independent risk factor for postoperative lung metastasis, and postoperative adjuvant therapy could improve the OS of lung metastases.ConclusionsThe DBRM was an independent risk factor for postoperative lung metastasis and adjuvant therapy could improve long-term survival.

EFFECT OF PS-K ON LONG-TERM SURVIVAL OF PRIMARY LUNG CANCER PATIENTS TREATED WITH RADIATION

1984 ◽  
Vol 34 (2) ◽  
pp. 133-140
Author(s):  
ATSUSHI OKAZAKI ◽  
NOBUAKI NAKAJIMA ◽  
KAZUSHIGE HAYAKAWA ◽  
YOSHIHIRO SAITO ◽  
OSAMU MITOMO ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Primary Lung Cancer ◽  
Term Survival ◽  
Long Term Survival ◽  
Lung Cancer Patients

Uniportal video-assisted thoracoscopy surgery in lung cancer: largest experience

2019 ◽  
Vol 27 (7) ◽  
pp. 559-564
Author(s):  
Balasubramanian Venkitaraman ◽  
Jiang Lei ◽  
Wu Liang ◽  
Cai Jianqiao
Keyword(s):  
Lung Cancer ◽  
Thoracoscopic Surgery ◽  
Primary Lung Cancer ◽  
Median Number ◽  
Short Term ◽  
Female Ratio ◽  
Oncological Outcomes ◽  
Video Assisted ◽  
Video Assisted Thoracoscopic Surgery

Background Uniportal video-assisted thoracoscopic surgery is one of the latest development in minimal invasive thoracic surgery. It is being increasing applied in various parts of the world for the treatment of lung cancer. Although the technique has become popular, there is a lack of largescale literature addressing the safety and oncological outcomes. We aimed to describe our experience, highlighting the short-term outcomes and oncological efficacy. Methods From July 2013 to December 2017, 441 uniportal video-assisted thoracoscopic procedures were carried out in patients with primary lung cancer and no metastatic disease. The male-to-female ratio was 240:201. The median age of the patients was 63 years (range10 to 85 years). Results The median number of mediastinal lymph node stations dissected and median number of mediastinal nodes were 5 and 14, respectively. Ten or more nodes were dissected in 93.1% of patients. All surgeries were complete R0 resection. Minor postoperative morbidity according to the Clavien-Dindo classification was 4%. Seven patients experienced major morbidity requiring intensive care management. There was no 30-day mortality. Conclusion Uniportal video-assisted thoracoscopic anatomical resection for lung cancer appears to have similar postoperative outcomes to multiport surgery in terms of short-term morbidity and oncological efficacy. Uniportal video-assisted thoracoscopic surgery can be offered as a standard of care for lung cancer surgery in centers with adequate surgical expertise. Long-term follow-up will be needed to establish the long-term oncological outcomes.

scholarly journals Video-assisted thoracoscopic lobectomy is feasible for selected patients with clinical N2 non-small cell lung cancer

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jae Kwang Yun ◽  
Geun Dong Lee ◽  
Sehoon Choi ◽  
Hyeong Ryul Kim ◽  
Yong-Hee Kim ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Thoracoscopic Surgery ◽  
Cohort Analysis ◽  
Survival Outcomes ◽  
Open Thoracotomy ◽  
Term Survival ◽  
Long Term Survival ◽  
Video Assisted ◽  
Advanced Stage Lung Cancer

Abstract Few studies have evaluated the usefulness of video-assisted thoracoscopic surgery (VATS) for advanced-stage lung cancer. We aimed to evaluate the feasibility of VATS for treating clinical N2 (cN2) lung cancer. A retrospective cohort analysis was performed with data from 268 patients who underwent lobectomy for cN2 disease from 2007 to 2016. Using propensity score-based inverse probability of treatment weighting (IPTW), perioperative and long-term survival outcomes were compared. We performed VATS and open thoracotomy on 121 and 147 patients, respectively. Overall, VATS was preferred for patients with peripherally located tumors (p < 0.001). After IPTW-adjustment, all preoperative information became similar between the groups. Compared to thoracotomy, VATS was associated with shorter hospitalization (7.7 days vs. 9.1 days, p = 0.028), despite equivalent complete resection rates (92.6% vs. 90.5%, p = 0.488) and dissected lymph nodes (mean, 31.9 vs. 29.4, p = 0.100). On IPTW-adjusted analysis, overall survival (50.5% vs. 48.4%, p = 0.127) and recurrence-free survival (60.5% vs 44.6%, p = 0.069) at 5 years were also similar between the groups. Among selected patients with resectable cN2 disease and peripherally located tumors, VATS is feasible, associated with shorter hospitalization and comparable perioperative and long-term survival outcomes, compared with open thoracotomy.

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