One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development

2006 ◽  
Vol 188 (1) ◽  
pp. 35-42 ◽  
Author(s):  
M. González-Santiago ◽  
E. Martín-Bautista ◽  
J.J. Carrero ◽  
J. Fonollá ◽  
L. Baró ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Olive Oil ◽  
Antioxidant Status ◽  
Blood Lipid ◽  
Phenolic Antioxidant ◽  
Blood Lipid Profile ◽  
Atherosclerosis Development

scholarly journals Effect of virgin olive oil and thyme phenolic compounds on blood lipid profile: implications of human gut microbiota

2015 ◽  
Vol 56 (1) ◽  
pp. 119-131 ◽  
Author(s):  
Sandra Martín-Peláez ◽  
Juana Ines Mosele ◽  
Neus Pizarro ◽  
Marta Farràs ◽  
Rafael de la Torre ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Gut Microbiota ◽  
Lipid Profile ◽  
Olive Oil ◽  
Virgin Olive Oil ◽  
Blood Lipid ◽  
Human Gut ◽  
Blood Lipid Profile ◽  
Human Gut Microbiota

scholarly journals Two Blends of Refined Rice Bran, Flaxseed, and Sesame Seed Oils Affect the Blood Lipid Profile of Chinese Adults with Borderline Hypercholesterolemia to a Similar Extent as Refined Olive Oil

2020 ◽  
Vol 150 (12) ◽  
pp. 3141-3151
Author(s):  
Sumanto Haldar ◽  
Long Hui Wong ◽  
Shia Lyn Tay ◽  
Jörg J Jacoby ◽  
Pengfei He ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Olive Oil ◽  
Hdl Cholesterol ◽  
Blood Lipid ◽  
Chinese Adults ◽  
Similar Extent ◽  
Blood Lipid Profile ◽  
Refined Olive Oil ◽  
Oil Blends ◽  
Time Treatment

ABSTRACT Background Individual vegetable oils have a characteristic fatty acids (FA) composition and unique phytonutrient profiles, enabling formulation of oil blends that may have health-promoting effects. Objective The primary objective of this study was to investigate effects of 2 oil blends made with refined rice bran, flaxseed, and sesame oils, with distinct monounsaturated to saturated FA, polyunsaturated to saturated FA, and omega-3 (n–3) to omega-6 FA ratios and different phytonutrient concentrations on blood lipid profile, compared with refined olive oil as a control. The secondary outcomes were other markers of cardiometabolic health. Methods A parallel-design, randomized controlled trial compared consumption of 30 g of allocated intervention oil per day for a period of 8 wk. The study recruited 143 borderline hypercholesterolemic (LDL cholesterol: 3.06–4.51 mmol/L) Chinese volunteers between 50 and 70 y old and with a BMI (kg/m2) ≤27.5. All outcomes were measured every 2 wk, and the time × treatment interactions and the main effects of treatment and time were analyzed using an intention-to-treat approach. Results Compared with baseline (week 0), there were significant reductions during the post-intervention time points in serum total cholesterol (−3.47%; P < 0.0001), LDL cholesterol (−4.16%; P < 0.0001), triglycerides (−10.3%; P < 0.0001), apoB (−3.93%; P < 0.0001), total to HDL-cholesterol (−3.44%; P < 0.0001) and apoB to apoA1 (−3.99%; P < 0.0001) ratios, systolic and diastolic blood pressures (−3.32% and −3.16%, respectively; both P < 0.0001), and serum glucose (−1.51%; P < 0.05) and a small but significant increase in body weight (+0.7%; P < 0.001) for all 3 intervention oils but no effects of intervention on HDL-cholesterol or apoA1 concentration. No significant effects of treatment or time × treatment interactions were found. Conclusions Using blended vegetable oils that are extensively consumed in Asia, this study found that specific oil blends can improve blood lipid profile and other cardiometabolic parameters, to a similar extent as refined olive oil, in Chinese adults with borderline hypercholesterolemia. This trial is registered at www.clinicaltrials.gov as NCT03964857.

732-P: Effect of Serum 25-Hydroxyvitamin D on Blood Lipid Profile in Type 2 Diabetics

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 732-P
Author(s):  
NAN LI ◽  
YANRU WANG ◽  
BING ZHU ◽  
HANG SUN ◽  
PENG YANG ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Blood Lipid ◽  
Blood Lipid Profile ◽  
Hydroxyvitamin D ◽  
Type 2 Diabetics ◽  
25 Hydroxyvitamin D

scholarly journals Co-Treatment of Purified Annatto Oil (Bixa orellana L.) and Its Granules (Chronic®) Improves the Blood Lipid Profile and Bone Protective Effects of Testosterone in the Orchiectomy-Induced Osteoporosis in Wistar Rats

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4720
Author(s):  
Arlindo César Matias Pereira ◽  
Helison de Oliveira Carvalho ◽  
Danna Emanuelle Santos Gonçalves ◽  
Karyny Roberta Tavares Picanço ◽  
Abrahão Victor Tavares de Lima Teixeira dos dos Santos ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Wistar Rats ◽  
Calcium Concentration ◽  
Calcium Content ◽  
Blood Lipid ◽  
Atomic Absorption Spectrophotometry ◽  
Protective Effects ◽  
Blood Lipid Profile ◽  
Bone Calcium ◽  
Weight Structure

This study aimed to evaluate and compare the effects of co-treatment with purified annatto oil (PAO) or its granules (GRA, Chronic®) with that of testosterone on the orchiectomy-induced osteoporosis in Wistar rats. After surgery, rats were treated from day 7 until day 45 with testosterone only (TES, 7 mg/kg, IM) or TES + PAO or GRA (200 mg/kg, p.o.). The following parameters were evaluated: food/water intake, weight, HDL, LDL, glucose, triglycerides (TG), total cholesterol (TC), alkaline phosphatase levels, blood phosphorus and calcium contents, femur weight, structure (through scanning electron microscopy), and calcium content (through atomic absorption spectrophotometry). Our results show that orchiectomy could significantly change the blood lipid profile and decrease bone integrity parameters. Testosterone reposition alone could improve some endpoints, including LDL, TC, bone weight, and bone calcium concentration. However, other parameters were not significantly improved. Co-treatment with PAO or GRA improved the blood lipid profile and bone integrity more significantly and improved some endpoints not affected by testosterone reposition alone (such as TG levels and trabeculae sizes). The results suggest that co-treatment with annatto products improved the blood lipid profile and the anti-osteoporosis effects of testosterone. Overall, GRA had better results than PAO.

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