Increased risk of coronary heart disease with hysterectomy in young women: A longitudinal follow-up study using a national health screening cohort

Maturitas ◽  
2021 ◽  
Author(s):  
Hyo Geun Choi ◽  
Yoon Seok Koh ◽  
Suk Woo Lee
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Young Women ◽  
National Health ◽  
Health Screening ◽  
Follow Up Study ◽  
Increased Risk

scholarly journals Association of nephrolithiasis with the risk of cardiovascular diseases: a longitudinal follow-up study using a national health screening cohort

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e040034
Author(s):  
So Young Kim ◽  
Woo Jin Bang ◽  
Chanyang Min ◽  
Hyo Geun Choi
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
National Health ◽  
Proportional Hazards Model ◽  
Health Screening ◽  
Cox Proportional Hazards Model ◽  
Secondary Outcome ◽  
Follow Up Study ◽  
Age And Sex

ObjectivesThe aim of this study was to explore the associations of stroke and ischaemic heart disease in patients with nephrolithiasis.DesignA longitudinal follow-up study.SettingData from the Korean National Health Insurance Service–Health Screening Cohort (2002–2013) were retrieved to identify the occurrence of nephrolithiasis.Participants and interventionsIn total, 19 103 patients with nephrolithiasis were matched at a 1:4 ratio with control participants for age, sex, income and region of residence.Primary and secondary outcome measuresThe occurrence of stroke and ischaemic heart disease was analysed in both patients with nephrolithiasis and control participants. The primary outcome was HRs of stroke and ischaemic heart disease in a stratified Cox proportional hazards model. Smoking, alcohol consumption, obesity and Charlson Comorbidity Index were adjusted for as covariates. Subgroup analyses according to age and sex were also performed.ResultsEight per cent (1615/19 103) of patients with nephrolithiasis and 7.2% (5476/76 412) of control participants had stroke. Nine per cent (1879/19 103) of patients with nephrolithiasis and 7.7% (5895/76 412) of control participants had ischaemic heart disease. Patients with nephrolithiasis had risks of stroke and ischaemic heart disease that were 1.18 times (95% CI=1.11 to 1.24) and 1.24 times (95% CI=1.18 to 1.31) those of the control participants, respectively. The age and sex subgroups showed consistent results.ConclusionsNephrolithiasis was associated with increased risks of stroke and ischaemic heart disease.

scholarly journals Correction: A sialoadenectomy is associated with an increased risk of coronary heart disease: A three-year follow-up study

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0243568
Author(s):  
Shih-Han Hung ◽  
Chin-Hui Su ◽  
Herng-Ching Lin ◽  
Chung-Chien Huang ◽  
Senyeong Kao
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Follow Up Study ◽  
Increased Risk

scholarly journals Increased Risk of Migraine in Patients with Temporomandibular Disorder: A Longitudinal Follow-Up Study Using a National Health Screening Cohort

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 724
Author(s):  
Soo-Hwan Byun ◽  
Chanyang Min ◽  
Dae-Myoung Yoo ◽  
Byoung-Eun Yang ◽  
Hyo-Geun Choi
Keyword(s):  
Blood Pressure ◽  
National Health ◽  
Temporomandibular Disorder ◽  
Fasting Blood Glucose ◽  
Health Screening ◽  
Control Group ◽  
Follow Up Study ◽  
Kaplan Meier ◽  
Increased Risk

Background: The aim of this study was to investigate the association between temporomandibular disorder (TMD) and migraine through a longitudinal follow-up study using population data from a national health screening cohort. Methods: This cohort study used data from the Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2015. Of the 514,866 participants, 3884 TMD patients were matched at a 1:4 ratio with 15,536 control participants. Crude models and models adjusted for obesity, smoking, alcohol consumption, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, and Charlson Comorbidity Index (CCI) scores were calculated. Chi-squared test, Kaplan–Meier analysis, and two-tailed log-rank test were used for statistical analysis. Stratified Cox proportional hazard models were used to assess hazard ratios (HR) and 95% confidence intervals (CIs) for migraine in both control groups. Results: The adjusted HR for migraine was 2.10 (95% CI: 1.81–2.44) in the TMD group compared to the control group, which was consistent in subgroup analyses according to age, sex, and Kaplan–Meier analysis. Conclusions: This study demonstrated that TMD patients have a higher risk of migraine. These results suggest that dentists can decrease the risk of migraine in TMD patients by managing TMD properly.

scholarly journals Associations between elevated kidney and liver biomarker ratios, metabolic syndrome and all-cause and coronary heart disease (CHD) mortality: analysis of the U.S. National Health and Nutrition Examination Survey (NHANES)

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Akinkunle Oye-Somefun ◽  
Jennifer L. Kuk ◽  
Chris I. Ardern
Keyword(s):  
Metabolic Syndrome ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
National Health ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Increased Risk ◽  
All Cause Mortality ◽  
The U.S

Abstract Background We examined the relationship between ratios of select biomarkers of kidney and liver function on all-cause and coronary heart disease (CHD) mortality, both in isolation, and in combination with metabolic syndrome (MetS), among adults (20 + years, n = 10,604). Methods Data was derived from the U.S. National Health and Nutrition Examination Survey (1999–2016) including public-use linked mortality follow-up files through December 31, 2015. Results Select biomarker ratios of kidney (UACR or albuminuria and BUN-CR) and liver (AST-ALT and GGT-ALP) function in isolation and in combination with MetS were associated with all-cause and CHD mortality. Compared to individuals with neither elevated biomarker ratios nor MetS (HR = 1.00, referent), increased risk of all-cause mortality was observed in the following groups: MetS with elevated UACR (HR, 95% CI = 2.57, 1.99–3.33), MetS with elevated AST-ALT (HR = 2.22, 1.61–3.07), elevated UACR without MetS (HR = 2.12, 1.65–2.72), and elevated AST-ALT without MetS (HR = 1.71, 1.35–2.18); no other biomarker ratios were associated with all-cause mortality. For cause-specific deaths, elevated risk of CHD mortality was associated with MetS with elevated UACR (HR = 1.67, 1.05–2.67), MetS with elevated AST-ALT (HR = 2.80, 1.62–4.86), and elevated BUN-CR without MetS (HR = 2.12, 1.12–4.04); no other biomarker ratios were associated with CHD mortality. Conclusion Future longitudinal studies are necessary to examine the utility of these biomarker ratios in risk stratification for chronic disease management.

scholarly journals A sialoadenectomy is associated with an increased risk of coronary heart disease: A three-year follow-up study

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0199135 ◽  
Author(s):  
Shih-Han Hung ◽  
Chin-Hui Su ◽  
Herng-Ching Lin ◽  
Chung-Chien Huang ◽  
Senyeong Kao
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Follow Up Study ◽  
Increased Risk

scholarly journals Joint association between education and polygenic risk score for incident coronary heart disease events: a longitudinal population-based study of 26 203 men and women

2021 ◽  
pp. jech-2020-214358
Author(s):  
Pekka Martikainen ◽  
Kaarina Korhonen ◽  
Aline Jelenkovic ◽  
Hannu Lahtinen ◽  
Aki Havulinna ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Risk Score ◽  
Density Lipoprotein ◽  
Population Based ◽  
Polygenic Risk Score ◽  
Genome Wide ◽  
Increased Risk ◽  
Region Of Residence

BackgroundGenetic vulnerability to coronary heart disease (CHD) is well established, but little is known whether these effects are mediated or modified by equally well-established social determinants of CHD. We estimate the joint associations of the polygenetic risk score (PRS) for CHD and education on CHD events.MethodsThe data are from the 1992, 1997, 2002, 2007 and 2012 surveys of the population-based FINRISK Study including measures of social, behavioural and metabolic factors and genome-wide genotypes (N=26 203). Follow-up of fatal and non-fatal incident CHD events (N=2063) was based on nationwide registers.ResultsAllowing for age, sex, study year, region of residence, study batch and principal components, those in the highest quartile of PRS for CHD had strongly increased risk of CHD events compared with the lowest quartile (HR=2.26; 95% CI: 1.97 to 2.59); associations were also observed for low education (HR=1.58; 95% CI: 1.32 to 1.89). These effects were largely independent of each other. Adjustment for baseline smoking, alcohol use, body mass index, igh-density lipoprotein (HDL) and total cholesterol, blood pressure and diabetes attenuated the PRS associations by 10% and the education associations by 50%. We do not find strong evidence of interactions between PRS and education.ConclusionsPRS and education predict CHD events, and these associations are independent of each other. Both can improve CHD prediction beyond behavioural risks. The results imply that observational studies that do not have information on genetic risk factors for CHD do not provide confounded estimates for the association between education and CHD.

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