Halogen Bonding Interactions in Halopyridine–Iodine Monochloride Complexes

SummaryThe properties of human fibrinogen labeled with 125-Iodine using Iodogen (1, 3, 4, 6-tetrachloro-3α, 6α-diphenylglycoluril) as an oxidizing agent were compared with those of an iodine monochloride labeled counterpart. It was found that thrombin clottability, binding to staphylococci, the relative specific radioactivity of the Aα, Bβ, and γ chains and in vivo clearance from plasma in rabbits were the same in these two labeled fibrinogen preparations. Labeling efficiency was higher when iodogen was used. It is concluded that human fibrinogen labeled with radioiodine using the Iodogen technique is suitable for studies in vitro and in vivo.

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The X40x10 Halogen Bonding Benchmark Revisited: Surprising Importance of (n-1)d Subvalence Correlation

10.26434/chemrxiv.5580007.v1 ◽

2017 ◽

Author(s):

Manoj Kumar Kesharwani ◽

Nitai Sylvetsky ◽

Debashree Manna ◽

Jan M.L. Martin

Keyword(s):

Dissociation Energy ◽

Noncovalent Interactions ◽

Halogen Bonding ◽

Coupled Cluster ◽

Dissociation Energies ◽

Iodine Species ◽

Explicitly Correlated ◽

High Level ◽

Cluster Methods ◽

Small Separation

<p>We have re-evaluated the X40x10 benchmark for halogen bonding using conventional and explicitly correlated coupled cluster methods. For the aromatic dimers at small separation, improved CCSD(T)–MP2 “high-level corrections” (HLCs) cause substantial reductions in the dissociation energy. For the bromine and iodine species, (n-1)d subvalence correlation increases dissociation energies, and turns out to be more important for noncovalent interactions than is generally realized. As in previous studies, we find that the most efficient way to obtain HLCs is to combine (T) from conventional CCSD(T) calculations with explicitly correlated CCSD-F12–MP2-F12 differences.</p>

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Faculty Opinions recommendation of Principles and applications of halogen bonding in medicinal chemistry and chemical biology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717963771.793498199 ◽

2014 ◽

Author(s):

Irene Weber

Keyword(s):

Chemical Biology ◽

Medicinal Chemistry ◽

Halogen Bonding

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Faculty Opinions recommendation of Principles and applications of halogen bonding in medicinal chemistry and chemical biology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717963771.793497893 ◽

2014 ◽

Author(s):

Xavier Barril ◽

Peter Schmidtke

Keyword(s):

Chemical Biology ◽

Medicinal Chemistry ◽

Halogen Bonding

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Faculty Opinions recommendation of Principles and applications of halogen bonding in medicinal chemistry and chemical biology.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717963771.793486179 ◽

2013 ◽

Author(s):

Jefferson Tilley

Keyword(s):

Chemical Biology ◽

Medicinal Chemistry ◽

Halogen Bonding

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Faculty Opinions recommendation of A systematic structural study of halogen bonding versus hydrogen bonding within competitive supramolecular systems.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725970284.793511837 ◽

2015 ◽

Author(s):

Patricia C Weber

Keyword(s):

Hydrogen Bonding ◽

Structural Study ◽

Halogen Bonding ◽

Supramolecular Systems

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Determination of subnanogram amounts of sulfur dioxide and sulfites by pneumatopotentiometry

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19862077 ◽

1986 ◽

Vol 51 (10) ◽

pp. 2077-2082 ◽

Cited By ~ 3

Author(s):

Jan Langmaier ◽

František Opekar

Keyword(s):

Sulfur Dioxide ◽

Redox Potential ◽

Sodium Hydroxide ◽

Porous Membrane ◽

Membrane Electrode ◽

Iodine Monochloride ◽

Membrane Pores ◽

Relative Standard ◽

Limit Of Quantitation

Gold porous membrane electrode has been used for the potentiometric determination of small amounts of sulfur dioxide absorbed in the solutions of sodium tetrachloromercurate or sodium hydroxide. Sulfur dioxide is released by the reaction with an acid into a stream of nitrogen and led to the electrode immersed into the solution of iodine monochloride. Part of SO2 penetrates through the membrane pores into the solution where it is oxidized. The electrode redox potential change is a measure of the SO2 concentration in the absorption solution. In the solution of 1 . 10-5 M[ICl2]- in 0.02 M-HClO4 the limit of quantitation was found to be 0.07 ng SO2 . ml-1. The relative standard deviations of 1.4% and 2.5% were found for the determinations of 10 ng and 0.5 ng of SO2, respectively. Higher concentrations of H2S interfere only in the hydroxide solution. About 10 samples can be analyzed per one hour.

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