scholarly journals Cooperation in a fluid swarm of fuel-free micro-swimmers

2022 ◽  
Vol 13 (1) ◽  
Author(s):  
Matan Yah Ben Zion ◽  
Yaelin Caba ◽  
Alvin Modin ◽  
Paul M. Chaikin

AbstractWhile motile bacteria display rich dynamics in dense colonies, the phoretic nature of artificial micro-swimmers restricts their activity when crowded. Here we introduce a new class of synthetic micro-swimmers that are driven solely by light. By coupling a light absorbing particle to a fluid droplet we produce a colloidal chimera that transforms optical power into propulsive thermo-capillary action. The swimmers’ internal drive allows them to operate for a long duration (days) and remain active when crowded, forming a high density fluid phase. We find that above a critical concentration, swimmers form a long lived crowded state that displays internal dynamics. When passive particles are introduced, the dense swimmer phase can re-arrange to spontaneously corral the passive particles. We derive a geometrical, depletion-like condition for corralling by identifying the role the passive particles play in controlling the effective concentration of the micro-swimmers.

2011 ◽  
Vol 7 (S279) ◽  
pp. 91-94
Author(s):  
C. C. Thöne ◽  
A. de Ugarte Postigo ◽  
C. Fryer ◽  
K. Page ◽  
J. Gorosabel ◽  
...  

AbstractThe Christmas burst, GRB 101225A, was one of the most controversial bursts in the last few years. Its exceptionally long duration but bright X-ray emission showing a thermal component followed by a strange afterglow with a thermal SED lead to two different interpretations. We present here our model ascribing this strange event to a new type of GRB progenitor consisting of a neutron star and an evolved main-sequence star in a very faint galaxy at redshift 0.33 while Campana et al. (2011) proposed a Galactic origin. New observations at several wavelengths might resolve the question between the two models in the near future.


2020 ◽  
Vol 12 (5) ◽  
pp. 1700
Author(s):  
Hosung Park ◽  
Seungsoo Nam ◽  
Daeseon Choi

This paper proposes an address authentication method based on a user’s location history. Address authentication refers to actual residence verification, which can be used in various fields such as personnel qualification, online identification, and public inquiry. In other words, accurate address authentication methods can reduce social cost for actual residence verification. For address authentication, existing studies discover the user’s regular locations, called location of interest (LOI), from the location history by using clustering algorithms. They authenticate an address if the address is contained in one of the LOIs. However, unnecessary LOIs, which are unrelated to the address may lead to false authentications of illegitimate addresses, that is, other users’ addresses or feigned addresses. The proposed method tries to reduce the authentication error rate by eliminating unnecessary LOIs with the distinguishing properties of the addresses. In other words, only few LOIs that satisfy the properties (long duration, high density, and consistency) are kept and utilized for address authentication. Experimental results show that the proposed method decreases the authentication error rate compared with previous approaches using time-based clustering and density-based clustering.


1983 ◽  
Vol 66 (11) ◽  
pp. 94-100 ◽  
Author(s):  
Eiji Maekawa ◽  
Koji Yoshida ◽  
Fumihiro Nihei

2013 ◽  
Vol 58 (1) ◽  
pp. 495-502 ◽  
Author(s):  
V. Balasubramanian ◽  
S. Solapure ◽  
H. Iyer ◽  
A. Ghosh ◽  
S. Sharma ◽  
...  

ABSTRACTTreatment of tuberculosis (TB) is impaired by the long duration and complexity of therapy and the rising incidence of drug resistance. There is an urgent need for new agents with improved efficacy, safety, and compatibility with combination chemotherapies. Oxazolidinones offer a potential new class of TB drugs, and linezolid—the only currently approved oxazolidinone—has proven highly effective against extensively drug-resistant (XDR) TB in experimental trials. However, widespread use of linezolid is prohibited by its significant toxicities. AZD5847, a novel oxazolidinone, demonstrates improvedin vitrobactericidal activity against both extracellular and intracellularM. tuberculosiscompared to that of linezolid. Killing kinetics in broth media and in macrophages indicate that the rate and extent of kill obtained with AZD5847 are superior to those obtained with linezolid. Moreover, the efficacy of AZD5847 was additive when tested along with a variety of conventional TB agents, indicating that AZD5847 may function well in combination therapies. AZD5847 appears to function similarly to linezolid through impairment of the mycobacterial 50S ribosomal subunit. Future studies should be undertaken to further characterize the pharmacodynamics and pharmacokinetics of AZD5847 in bothin vitroand animal models as well is in human clinical trials.


2002 ◽  
Vol 173 (1) ◽  
pp. 103-111 ◽  
Author(s):  
J Ragoobir ◽  
DR Abayasekara ◽  
KR Bruckdorfer ◽  
AE Michael

Low-density lipoproteins (LDL) have been consistently reported to stimulate ovarian steroidogenesis, apparently by the provision of cholesterol as a steroidogenic substrate. Recent studies suggest that high-density lipoproteins (HDL) can also deliver cholesterol to support progesterone synthesis in human granulosa-lutein cells. Therefore, this study investigated the contributions of (i) cholesterol delivery, (ii) cyclic AMP and (iii) protein kinase C (PKC) in the steroidogenic responses of human granulosa-lutein cells to HDL and LDL. Over a 24-h treatment incubation, HDL stimulated a larger increase in progesterone output than did LDL at equivalent cholesterol concentrations. Moreover, at equal protein concentrations (100 microg protein/ml), HDL doubled progesterone production by cells co-treated with a maximally effective concentration of 22R-hydroxycholesterol, whereas LDL had no effect on the progesterone response to this membrane-permeable sterol. These observations indicate that the progesterone response to HDL is not solely due to the delivery of cholesterol as a steroidogenic substrate. Over 24 h, the stimulation of progesterone synthesis by HDL was additive with the response to a maximally effective concentration of dibutyryl-cAMP, but was unaffected by the down-regulation of PKC activity (by chronic pre-treatment with a tumour-promoting phorbol ester). We have concluded that HDL appears to stimulate progesterone production in human granulosa-lutein cells by a mechanism not solely reliant on cholesterol delivery.


1997 ◽  
Author(s):  
Martin K. Casstevens ◽  
Ryszard Burzynski ◽  
John F. Weibel ◽  
Charles W. Spangler ◽  
Guang S. He ◽  
...  

1988 ◽  
Vol 10 (10) ◽  
pp. 25
Author(s):  
Olavo José Bortolotto

The Caçapava do Sul region, State of Rio Grande do Sul, is characterized by the occurrence of a granitic batholith (Caçapava Granite) that is surrounded by a belt of metamorphites belonging to the Porongos Group, assigned to Upper Precanbrian by RIBEIRO et alii (1966). Among the metamorphites occur a carbonatic rock body, lens shaped, with clear contacts, interpenetrated by granitic apophises and with an outcrop of about 17 km2. The study of the metamorphism showed that these rocks were affected termically by the Caçapava Granite and its apophises, as become evident by the metamorphic zoneation in rocks belonging to a Piroxene Hornfels Facies, near the contact, and Albita-Epidoto Hornfels Facies, placed farther away. The structure generaly isotropic, the preservation of the polimorphous orthoclase, the contemporariness of the granitic body and its wall rocks (Brazilian Cicle) and having in view hat the wall rocks belong to a Green Schists Facies (BITENCOURT, 1983), make evident the shallow emplacement of the Caçapava Granite and allow to estimate the highest metamorphic temperatures at about 560°C. The total pressure and the pressure of fluid phase were estimated at 1.000 bars, which also conforms to the shallow emplacement (3 - 4 km) of the granitic body. The analyses of the metamorphism of these rocks, based on T – XCO2 diagrams for the CaO-MgO-SiO2-CO2-H2O system, maked evidente equilibrium and disequilibrium paragenesis which conforms to the Caçapava granitic magma that didn't favour an homogeneous termic distribution and of long duration.


2015 ◽  
Vol 6 (5) ◽  
pp. 3139-3147 ◽  
Author(s):  
Sergio Carrasco ◽  
Elena Benito-Peña ◽  
David R. Walt ◽  
María C. Moreno-Bondi

In this article we describe a new class of high-density optical microarrays based on molecularly imprinted microsphere sensors that directly incorporate specific recognition capabilities to detect enrofloxacin (ENRO), an antibiotic widely used for both human and veterinary applications.


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