scholarly journals Acute Response of Sclerostin to Whole-body Vibration with Blood Flow Restriction

2021 ◽  
Author(s):  
Kyle S Gapper ◽  
Sally Stevens ◽  
Rona Antoni ◽  
Julie Hunt ◽  
Sarah J Allison
Keyword(s):  
Alkaline Phosphatase ◽  
Blood Flow ◽  
Whole Body Vibration ◽  
Blood Flow Restriction ◽  
Whole Body ◽  
Specific Alkaline Phosphatase ◽  
Body Vibration ◽  
Bone Specific Alkaline Phosphatase ◽  
Flow Restriction ◽  
Acute Response

AbstractBlood flow restriction may augment the skeletal response to whole-body vibration. This study used a randomised, crossover design to investigate the acute response of serum sclerostin and bone turnover biomarkers to whole-body vibration with blood flow restriction. Ten healthy males (mean±standard deviation; age: 27±8 years) completed two experimental conditions separated by 7 days: (i) whole-body vibration (10 1-minute bouts of whole-body vibration with 30 s recovery) or (ii) whole-body vibration with lower-body blood flow restriction (10 cycles of 110 mmHg inflation with 30 s deflation during recovery). Fasting blood samples were obtained immediately before and immediately after exercise, then 1 hour, and 24 hours after exercise. Serum samples were analysed for sclerostin, cross-linked C-terminal telopeptide of type I collagen, and bone-specific alkaline phosphatase. There was a significant time × condition interaction for bone-specific alkaline phosphatase (p=0.003); bone-specific alkaline phosphatase values at 24 hours post-exercise were significantly higher following whole-body vibration compared to combined whole-body vibration and blood flow restriction (p=0.028). No significant time × condition interaction occurred for any other outcome measure (p>0.05). These findings suggest that a single session of whole-body vibration combined with blood flow restriction does not significantly affect serum sclerostin or bone turnover biomarkers.

scholarly journals Effect of acute whole-body vibration exercise with blood flow restriction on vascular endothelial growth factor response

Kinesiology ◽  
2018 ◽  
Vol 50 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Wu Chih-Min ◽  
Chen Wen-Chyuan ◽  
Cai Zong-Yan
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Blood Flow ◽  
Growth Factor ◽  
Whole Body Vibration ◽  
Blood Flow Restriction ◽  
Whole Body ◽  
Vascular Endothelial ◽  
Body Vibration ◽  
Flow Restriction ◽  
Endothelial Growth Factor

This study aimed to investigate the effects of the whole-body vibration (WBV) exercise with and without blood flow restriction (BFR) on heart rate (HR), oxygen saturation (SpO2), and circulating vascular endothelial growth factor (VEGF) response. Ten physically inactive male adults participated in this study and completed WBV (frequency: 26 Hz; amplitude: 4 mm; 10 sets for 1 min, with 1-2 min of rest between sets) and WBV + BFR sessions in a repeated measures crossover design, with a 1-week interval separating the sessions. In the WBV + BFR session, participants wore a BFR device inflated to 140 mmHg on the proximal portion of the thigh muscle. Results indicated that WBV + BFR caused a greater HR response than WBV alone (p<.05). Neither WBV + BFR nor WBV sessions caused a significant change in SpO2 (p>.05). Only the WBV + BFR session caused a significant increase in the VEGF response (p<.05), and WBV + BFR elicited a significantly higher VEGF response than did WBV after exercise (p<.05). In conclusion, an acute bout of WBV + BFR exercise magnifies the HR response relative to WBV exercise and induces an increase in circulating VEGF values. These alterations seem unrelated to systematic SpO2.

scholarly journals The Effect Of Blood Flow Restriction And Whole-body Vibration As A Warm-up Strategy

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 464
Author(s):  
Jonathan Salinas ◽  
Natalie Castillo ◽  
Aaron Garcia ◽  
Jessica Martinez ◽  
Ricardo Parra ◽  
...  
Keyword(s):  
Blood Flow ◽  
Whole Body Vibration ◽  
Blood Flow Restriction ◽  
Whole Body ◽  
Warm Up ◽  
Body Vibration ◽  
Flow Restriction

Blood flow restriction increases myoelectric activity and metabolic accumulation during whole-body vibration

2019 ◽  
Vol 119 (6) ◽  
pp. 1439-1449 ◽  
Author(s):  
Christoph Centner ◽  
Ramona Ritzmann ◽  
Stephan Schur ◽  
Albert Gollhofer ◽  
Daniel König
Keyword(s):  
Blood Flow ◽  
Whole Body Vibration ◽  
Blood Flow Restriction ◽  
Whole Body ◽  
Myoelectric Activity ◽  
Body Vibration ◽  
Flow Restriction

scholarly journals Effects of Whole Body Vibration on Glycemic Indices and Peripheral Blood Flow in Type II Diabetic Patients

2017 ◽  
Vol 24 (4) ◽  
pp. 55-63 ◽  
Author(s):  
Nuttaset Manimmanakorn ◽  
◽  
Apiwan Manimmanakorn ◽  
Warinthorn Phuttharak ◽  
Michael J Hamlin ◽  
...  
Keyword(s):  
Blood Flow ◽  
Peripheral Blood ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Diabetic Patients ◽  
Peripheral Blood Flow ◽  
Type Ii ◽  
Body Vibration ◽  
Glycemic Indices

Regional Cerebral Blood Flow and Vasoactive Intestinal Polypeptide (VIP) in Rat Exposed to Whole-body Vibration Stress

1994 ◽  
Vol 13 (1) ◽  
pp. 1-6
Author(s):  
Hiroyuki Nakamura ◽  
Hirofumi Nagase ◽  
Takao Okazawa ◽  
Masami Yoshida ◽  
Akira Okada
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Frontal Cortex ◽  
Vasoactive Intestinal Polypeptide ◽  
Regional Cerebral Blood Flow ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Regional Cerebral Blood ◽  
Cortical Blood Flow ◽  
Body Vibration

To clarify the involvement of vasoactive intestinal polypeptide (VIP) in regional cerebral circulation during whole-body vibration (WBV), we determined regional cerebral blood flow and VIP-like immunoreactivity (VIP-LI) in rats following WBV for 90 min. at various accelerations (0, 2G and 4G rms), using the hydrogen gas electrolytic method. Interference electrodes were inserted into the frontal cortex and the hippocampus. Although we observed no change in hippocampal blood flow, the frontal cortical blood flow increased during the exposure in a manner that was dependent upon the acceleration. There was a significant reduction in hippocampal VIP-LI following WBV at an acceleration of 4G. The association between frontal cortical blood flow and hippocampal VIP-LI was significantly negative. Our results indicated that a local increase in blood flow in the frontal cortex of rats was induced by WBV. This increase seemed to be involved in the neural activation induced by WBV. Hippocampal VIP may have a role in the physiological regulation of frontal cortical circulation during WBV stress.

scholarly journals Reduced Bone Mineral Density and Increased Bone Metabolism Rate in Young Adult Patients with 21-Hydroxylase Deficiency

2006 ◽  
Vol 91 (11) ◽  
pp. 4453-4458 ◽  
Author(s):  
Mariateresa Sciannamblo ◽  
Gianni Russo ◽  
Debora Cuccato ◽  
Giuseppe Chiumello ◽  
Stefano Mora
Keyword(s):  
Bone Mineral Density ◽  
Alkaline Phosphatase ◽  
Bone Metabolism ◽  
Type I Collagen ◽  
Whole Body ◽  
Type I ◽  
Healthy Controls ◽  
Mineral Density ◽  
Specific Alkaline Phosphatase ◽  
Bone Specific Alkaline Phosphatase

Abstract Context: Patients with congenital adrenal hyperplasia (CAH) receive glucocorticoids as replacement therapy. Glucocorticoid therapy is the most frequent cause of drug-induced osteoporosis. Objective: The objective of the study was to evaluate bone mineral density (BMD) and bone metabolism in CAH patients. Design: This was a cross-sectional observational study. Setting: The study was conducted at a referral center for pediatric endocrinology. Patients and Other Participants: Thirty young patients with the classical form of CAH (aged 16.4–29.7 yr) treated with glucocorticoid from diagnosis (duration of treatment 16.4–29.5 yr) and 138 healthy controls (aged 16.0–30.0 yr) were enrolled. Main Outcome Measures: BMD was measured in the lumbar spine and whole body by dual-energy x-ray absorptiometry. Bone formation and resorption rates were estimated by serum measurements of bone-specific alkaline phosphatase and C-terminal telopeptide of type I collagen, respectively. Results: CAH patients were shorter than controls (women −6.8 and men −13.3 cm). Therefore, several methods were used to account for the effect of this difference on bone measurements. Whole-body BMD measurements were significantly lower, compared with controls (P < 0.03), after controlling for height (on average −2.5% in females and −9.3% in male patients). No differences were found in lumbar spine measurements. Bone-specific alkaline phosphatase and C-terminal telopeptide of type I collagen serum concentrations were higher in CAH patients than control subjects (P < 0.04). BMD measurements and bone metabolism markers did not correlate with the actual glucocorticoid dose or mean dose over the previous 7 yr. Conclusions: Young adult patients with the classical form of CAH have decreased bone density values, compared with healthy controls. This may put them at risk of developing osteoporosis early in life.

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