scholarly journals Aerobic Exercise Training Attenuates Blood Pressure Response During Maximal Aerobic Exercise and Improves Endothelial Function in Chronic Kidney Disease

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Justin Sprick ◽  
Joe Nocera ◽  
Doree Morison ◽  
Kevin Mammino ◽  
Derick Rapista ◽  
...  
2002 ◽  
Vol 92 (4) ◽  
pp. 1434-1442 ◽  
Author(s):  
Michael D. Brown ◽  
Donald R. Dengel ◽  
Robert V. Hogikyan ◽  
Mark A. Supiano

To test whether changes in sympathetic nervous system (SNS) activity or insulin sensitivity contribute to the heterogeneous blood pressure response to aerobic exercise training, we used compartmental analysis of [3H]norepinephrine kinetics to determine the extravascular norepinephrine release rate (NE2) as an index of systemic SNS activity and determined the insulin sensitivity index (SI) by an intravenous glucose tolerance test, before and after 6 mo of aerobic exercise training, in 30 (63 ± 7 yr) hypertensive subjects. Maximal O2consumption increased from 18.4 ± 0.7 to 20.8 ± 0.7 ml · kg−1· min−1( P = 0.02). The average mean arterial blood pressure (MABP) did not change (114 ± 2 vs. 114 ± 2 mmHg); however, there was a wide range of responses (−19 to +17 mmHg). The average NE2did not change significantly (2.11 ± 0.15 vs. 1.99 ± 0.13 μg · min−1· m−2), but there was a significant positive linear relationship between the change in NE2and the change in MABP ( r = 0.38, P = 0.04). SIincreased from 2.81 ± 0.37 to 3.71 ± 0.42 μU × 10−4· min−1· ml−1( P = 0.004). The relationship between the change in SIand the change in MABP was not statistically significant ( r = −0.03, P = 0.89). When the changes in maximal O2consumption, percent body fat, NE2, and SIwere considered as predictors of the change in MABP, only NE2was a significant independent predictor. Thus suppression of SNS activity may play a role in the reduction in MABP and account for a portion of the heterogeneity of the MABP response to aerobic exercise training in older hypertensive subjects.


2019 ◽  
Vol Volume 12 ◽  
pp. 711-718 ◽  
Author(s):  
Mauro José de Deus Morais ◽  
Luiz Carlos de Abreu ◽  
Fabiano Santana de Oliveira ◽  
Italla Maria Pinheiro Bezerra ◽  
Rodrigo Daminello Raimundo ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1327 ◽  
Author(s):  
Ana Luiza Amaral ◽  
Igor M. Mariano ◽  
Victor Hugo V. Carrijo ◽  
Tállita Cristina F. de Souza ◽  
Jaqueline P. Batista ◽  
...  

Objective: To verify if acute intake of beetroot juice potentiates post-exercise hypotension (PEH) in hypertensive postmenopausal women. Methods: Thirteen hypertensive postmenopausal women (58.1 ± 4.62 years and 27.4 ± 4.25 kg/m²) were recruited to participate in three experimental sessions, taking three different beverages: Beetroot juice (BJ), placebo nitrate-depleted BJ (PLA), and orange flavored non-caloric drink (OFD). The participants performed moderate aerobic exercise training on a treadmill, at 65–70% of heart rate reserve (HRR), for 40 min. After an overnight fast, the protocol started at 07h when the first resting blood pressure (BP) was measured. The beverage was ingested at 07h30 and BP was monitored until the exercise training started, at 09h30. After the end of the exercise session, BP was measured every 15 min over a 90-min period. Saliva samples were collected at rest, immediately before and after exercise, and 90 min after exercise for nitrite (NO2−) analysis. Results: There was an increase in salivary NO2− with BJ intake when compared to OFD and PLA. A slight increase in salivary NO2− was observed with PLA when compared to OFD (p < 0.05), however, PLA resulted in lower salivary NO2− when compared to BJ (p < 0.001). There were no changes in salivary NO2− with the OFD. Systolic and diastolic BP decreased (p < 0.001) on all post exercise time points after all interventions, with no difference between the three beverages. Conclusion: Acute BJ intake does not change PEH responses in hypertensive postmenopausal women, even though there is an increase in salivary NO2−.


2017 ◽  
Vol 22 (3) ◽  
pp. 1452-1463 ◽  
Author(s):  
Wilson Max Almeida Monteiro De Moraes ◽  
Pamella Ramona Moraes de Souza ◽  
Nathalie Alves da Paixão ◽  
Luís Gustavo Oliveira de Sousa ◽  
Daniel Araki Ribeiro ◽  
...  

Nephrology ◽  
2016 ◽  
Vol 22 (1) ◽  
pp. 72-78 ◽  
Author(s):  
Samuel Headley ◽  
Michael Germain ◽  
Richard Wood ◽  
Jyovani Joubert ◽  
Charles Milch ◽  
...  

Author(s):  
Rakhbeer Singh Boparai ◽  
Rachel J Skow ◽  
Sauleha Farooq ◽  
Craig D Steinback ◽  
Margie H Davenport

We assessed the impact of a structured lower-limb aerobic exercise training intervention during pregnancy on brachial artery endothelial function, shear rate and patterns, and forearm blood flow and reactive hyperemia. Twenty-seven pregnant women were recruited and randomized into either a control group (n=11; 31.0 ± 0.7 years), or an exercise intervention group (n=16; 32.6 ± 0.9 years; NCT02948439). The exercise group completed 40 minutes of aerobic exercise (50-70% heart rate reserve) 3-4 times per week, between the second and third trimester of pregnancy. Endothelial function was assessed using flow-mediated dilation (FMD, normalized for shear stress) pre- (16-20 weeks) and post-intervention (34-36 weeks). The exercise training group experienced an attenuated increase in mean arterial pressure (MAP) relative to the control group (∆MAP exercise: +2± 2 mmHg vs. control: +7±3 mmHg; p=0.044) from pre- to post-intervention. % FMD change corrected for shear stress was not different between groups (p=0.460); however, the post occlusion mean flow rate (exercise: 437±32 mL/min vs. control: 364±35 mL/min; p=0.001) and post occlusion anterograde flow rate (exercise: 438±32 mL/min vs. control: 364±46 mL/min;p=0.001) were larger for the exercise training group compared to controls, post-intervention. Although endothelial function was not different between groups, we observed an increase in microcirculatory dilatory capacity, as suggested by the augmented reactive hyperemia in the exercise training group. Novelty: • Endothelial function was not altered with exercise training during pregnancy. • Exercise training did contribute to improved cardiovascular outcomes, which may have been associated with augmented reactive hyperaemia, indicative of increased microcirculatory dilatory capacity


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