Raynaud's phenomenon: blood supply to fingers during indirect cooling, evaluated by laser Doppler flowmetry

2008 ◽  
Vol 6 (6) ◽  
pp. 481-488 ◽  
Author(s):  
M. Engelhart ◽  
J. K. Kristensen
VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.


2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Paweł Maga ◽  
Brandon Michael Henry ◽  
Elizabeth K. Kmiotek ◽  
Iwona Gregorczyk-Maga ◽  
Paweł Kaczmarczyk ◽  
...  

The aim of this study was to measure the sensitivity and specificity of transcutaneous oxygen tension and postocclusive hyperemia testing using laser Doppler flowmetry in patients with primary Raynaud’s phenomenon. One hundred patients and one hundred controls were included in the study. Baseline microvascular blood flow and then time to peak flow following occlusion were measured using laser Doppler flowmetry. Afterwards, the transcutaneous oxygen tension was recorded. The sensitivities of baseline microvascular blood flow, postocclusive time to peak flow, and transcutaneous oxygen tension were 79%, 79%, and 77%, respectively. The postocclusive time peak flow had a superior specificity of 90% and area under the curve of 0.92 as compared to 66% and 0.80 for baseline microvascular flow and 64% and 0.76 for transcutaneous oxygen tension. Time to postocclusive peak blood flow measured by laser Doppler flowmetry is a highly accurate test for differentiating patients with primary Raynaud’s phenomenon from healthy controls.


2017 ◽  
Vol 7 (3) ◽  
pp. 38-43
Author(s):  
Valentin N Krupin ◽  
Alexey V Krupin ◽  
A Nashivochnikova Natalya

73 patients with chronic bacterial prostatitis were undergone several methods of investigations, such as pelvic rheography, rheoprostatography, laser doppler flowmetry and ultrasonic dopplerography for studying its hemodynamics.The results obtained indicate a violation of the blood supply to the prostate, which depends not only of the severity of the inflammatory process, but on the degree of hemodynamic disturbances in the small pelvis too and caused by a violation of the tone of the vessels of the prostate as well. (For citation: Krupin VN, Krupin AV, Nashivochnikova NA. Evaluation of blood flow in prostate in patients with chronic bacterial prostatitis. Urologicheskie vedomosti. 2017;7(3):38-43. doi: 10.17816/uroved7338-43).


1994 ◽  
Vol 18 (3) ◽  
pp. 417-420 ◽  
Author(s):  
Kenth Johansson ◽  
Stefan Ander ◽  
Sten Lennquist ◽  
Staffan Smeds

Sign in / Sign up

Export Citation Format

Share Document