Vertical Inheritance Facilitates Interspecies Diversification in Biosynthetic Gene Clusters and Specialized Metabolites
Keyword(s):
Microbial natural products are traditionally exploited for their pharmaceutical potential, yet our understanding of the evolutionary processes driving BGC evolution and compound diversification remains poorly developed. While HGT is recognized as an integral driver of BGC distributions, we find that the effects of vertical inheritance on BGC diversification had direct implications for species-level specialized metabolite production.
2020 ◽
2015 ◽
Vol 13
(8)
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pp. 509-523
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2019 ◽
2017 ◽
Vol 35
(8)
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pp. 936-949
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2019 ◽
Vol 113
(4)
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pp. 511-520
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