Structural basis for the 3′ – 5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

Structural Insights into Gene Expression and Protein Synthesis - Series in Structural Biology ◽

10.1142/9789811215865_0025 ◽

2020 ◽

pp. 245-253

Author(s):

Lorena S. Beese ◽

Thomas A. Steitz

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Metal Ion ◽

Structural Basis ◽

Exonuclease Activity ◽

Dna Polymerase I ◽

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Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.

The EMBO Journal ◽

10.1002/j.1460-2075.1991.tb07917.x ◽

1991 ◽

Vol 10 (1) ◽

pp. 25-33 ◽

Author(s):

L. S. Beese ◽

T. A. Steitz

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Metal Ion ◽

Structural Basis ◽

Exonuclease Activity ◽

Dna Polymerase I ◽

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Differential effect of on the DNA polymerase activity, the 5′ → 3′-exonuclease activity and the 3′ → 5′-exonuclease activity of DNA polymerase I of Escherichia coli

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis ◽

10.1016/0005-2787(81)90171-4 ◽

1981 ◽

Vol 654 (2) ◽

pp. 187-193 ◽

Author(s):

Hans Klenow ◽

Kay Overgaard-Hansen

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Differential Effect ◽

Polymerase Activity ◽

Exonuclease Activity ◽

Dna Polymerase I ◽

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The excision of AP sites by the 3'-5' exonuclease activity of the Klenow fragment of Escherichia coli DNA polymerase I

FEBS Letters ◽

10.1016/0014-5793(84)80605-5 ◽

1984 ◽

Vol 178 (2) ◽

pp. 223-227 ◽

Author(s):

Véronique Bailly ◽

Walter G. Verly

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Exonuclease Activity ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Ap Sites ◽

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Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates

Journal of Molecular Biology ◽

10.1006/jmbi.1997.1586 ◽

1998 ◽

Vol 277 (2) ◽

pp. 363-377 ◽

Author(s):

Chad A Brautigam ◽

Thomas A Steitz

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Exonuclease Activity ◽

Dna Polymerase I ◽

Structural Principles ◽

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Binding of captan to DNA polymerase I from Escherichia coli and the concomitant effect on 5' .fwdarw. 3' exonuclease activity

Biochemistry ◽

10.1021/bi00433a015 ◽

1989 ◽

Vol 28 (7) ◽

pp. 2843-2849 ◽

Author(s):

M. J. Freeman-Wittig ◽

William Welch ◽

Roger A. Lewis

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Exonuclease Activity ◽

Dna Polymerase I ◽

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Mechanism of selective inhibition of 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by nucleoside 5'-monophosphates

Biochemistry ◽

10.1021/bi00602a004 ◽

1978 ◽

Vol 17 (9) ◽

pp. 1603-1606 ◽

Author(s):

Benito G. Que ◽

Kathleen M. Downey ◽

Antero G. So

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Selective Inhibition ◽

Exonuclease Activity ◽

Dna Polymerase I ◽

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Faculty Opinions recommendation of Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1014299.195701 ◽

2003 ◽

Author(s):

Frances Arnold

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Gene Evolution ◽

Dna Polymerase I ◽

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Oxygen-dependent cleavage of DNA by the 1,10-phenanthroline . cuprous complex. Inhibition of Escherichia coli DNA polymerase I.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)86305-6 ◽

1979 ◽

Vol 254 (24) ◽

pp. 12269-12272

Author(s):

D.S. Sigman ◽

D.R. Graham ◽

V. D'Aurora ◽

A.M. Stern

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Dna Polymerase I ◽

Polymerase I ◽

Cuprous Complex

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Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Chain termination and modulation by polynucleotides.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)34139-5 ◽

1982 ◽

Vol 257 (16) ◽

pp. 9770-9780 ◽

Author(s):

S D Detera ◽

S H Wilson

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Chain Termination ◽

Large Fragment ◽

Dna Polymerase I ◽

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D(M6ATP) as a probe of the fidelity of base incorporation into polynucleotides by Escherichia coli DNA polymerase I.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)38194-2 ◽

1978 ◽

Vol 253 (3) ◽

pp. 935-939

Author(s):

J.D. Engel ◽

P.H. von Hippel

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Dna Polymerase I ◽

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