scholarly journals Prevention and Nursing Research of PICC Catheter-Related Complications in Patients with Digestive System Malignant Tumor Based on Smart Medical Block Chain

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Ruxian Huang ◽  
Yan Jiang ◽  
Xiaoyun Le
Keyword(s):  
Malignant Tumor ◽  
Digestive System ◽  
Malignant Tumors ◽  
Venous Catheter ◽  
Tumor Patients ◽  
Digestive System Cancer ◽  
Drug Extravasation ◽  
Block Chain ◽  
Multiple Puncture ◽  
Local Stimulation

Malignant tumors of digestive system mainly include gastric cancer, colorectal cancer, and esophageal cancer, which generally need chemotherapy. PICC refers to peripherally inserted central venous catheter, which plays an important role in the treatment of malignant tumor patients with chemotherapy, and it has the characteristics of high success rate of puncture and reducing the pain of patients. Its principle is to use PICC catheter for drug delivery, which can effectively reduce the pain of tumor patients for multiple puncture, and also can avoid drug extravasation or local stimulation of drugs. However, PICC catheter-related complications cannot be ignored, to some extent, directly affect the treatment effect of patients, and increase the pain and burden of patients. Therefore, this paper proposes a study of PICC catheter-related complications and protective nursing for patients with digestive system cancer based on smart medical block chain. First of all, using the method of literature, this paper deeply studied the combination of smart medicine and block chain and further strengthened the research on PICC catheter-related complications. Based on this, we designed a study on the prevention and nursing of PICC catheter-related complications in patients with digestive system cancer. Before the implementation of nursing, the incidence of complications in patients with digestive system cancer was 17.35%; after the implementation of nursing, the incidence of complications decreased to 4.08%. The purpose of this study is to analyze the causes through clinical research and put forward the protective nursing measures of related diseases, so as to reduce the incidence of PICC-related complications.

Hepatocyte ultrastructural alterations in perimetastatic areas

1996 ◽  
Vol 54 ◽  
pp. 768-769
Author(s):  
H. J. Finol ◽  
M. E. Correa ◽  
L.A. Sosa ◽  
A. Márquez ◽  
N.L. Díaz
Keyword(s):  
Malignant Tumor ◽  
Malignant Tumors ◽  
Surrounding Tissue ◽  
Ultrastructural Changes ◽  
Pancreas Carcinoma ◽  
Duct Carcinoma ◽  
Tissue Samples ◽  
Primary Malignant Tumor ◽  
Transmission Electron ◽  
Remote Sites

In classical oncological literature two mechanisms for tissue aggression in patients with cancer have been described. The first is the progressive invasion, infiltration and destruction of tissues surrounding primary malignant tumor or their metastases; the other includes alterations produced in remote sites that are not directly affected by any focus of disease, the so called paraneoplastic phenomenon. The non-invaded tissue which surrounds a primary malignant tumor or its metastases has been usually considered a normal tissue . In this work we describe the ultrastructural changes observed in hepatocytes located next to metastases from diverse malignant tumors.Hepatic biopsies were obtained surgically in patients with different malignant tumors which metatastized in liver. Biopsies included tumor mass, the zone of macroscopic contact between the tumor and the surrounding tissue, and the tissue adjacent to the tumor but outside the macroscopic area of infiltration. The patients (n = 5), 36–75 years old, presented different tumors including rhabdomyosarcoma, leiomyosarcoma, pancreas carcinoma, biliar duct carcinoma and colon carcinoma. Tissue samples were processed with routine techniques for transmission electron microscopy and observed in a Hitachi H-500 electron microscope.

THE PROGNOSTIC VALUE OF PD-L1 EXPRESSION IN TUMOR AND IMMUNE CELLS IN SQUAMOUS CELL CARCINOMA OF THE ORAL MUCOSA

2017 ◽  
Vol 63 (5) ◽  
pp. 759-765
Author(s):  
Svetlana Kutukova ◽  
Natalya Belyak ◽  
Grigoriy Raskin ◽  
Marina Mukhina ◽  
Georgiy Manikhas ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Malignant Tumor ◽  
Immune Cells ◽  
Prognostic Value ◽  
Hard Palate ◽  
Malignant Tumors ◽  
Small Cell ◽  
Alveolar Process ◽  
Small Cell Lung ◽  
Lower Jaw

The most frequent of malignant tumor cites of the oral mucosa are tongue - 55 %, mucosa of the cheek - 12 %, the fundus of the oral cavity - 10 %, the alveolar process of the upper jaw and the hard palate - 9 %, the alveolar process of the lower jaw - 6 %, the soft palate - 2 %. Malignant tumor cells carry PD-L1 ligands on their surface and its expression level is often correlated with an unfavorable prognosis in particular for such tumors as melanoma, kidney cancer and non-small cell lung cancer. It is relevant to evaluate the correlation between overexpression of PD-L1 and overall survival in patients with malignant tumors of the oral mucosa.

scholarly journals Organoid Technology and Clinical Applications in Digestive System Cancer

Engineering ◽  
2021 ◽  
Author(s):  
Xiaofang Zhao ◽  
Youhai Jiang ◽  
Chunliang Liu ◽  
Minghui Hou ◽  
Hongyang Wang ◽  
...  
Keyword(s):  
Digestive System ◽  
Clinical Applications ◽  
Digestive System Cancer

scholarly journals Prognostic and predictive values of PD-L1 expression in patients with digestive system cancer: a meta-analysis

2017 ◽  
Vol Volume 10 ◽  
pp. 3625-3634 ◽  
Author(s):  
Cong Dai ◽  
Meng Wang ◽  
Jun Lu ◽  
Zhiming Dai ◽  
Shuai Lin ◽  
...  
Keyword(s):  
Digestive System ◽  
Meta Analysis ◽  
Predictive Values ◽  
Digestive System Cancer

scholarly journals ABO histo-blood groups and Rh systems in relation to malignant tumors of the digestive tract in Bosnia and Herzegovina

2008 ◽  
Vol 60 (4) ◽  
pp. 593-599 ◽  
Author(s):  
Snezana Jovanovic-Cupic ◽  
Gorana Stamenkovic ◽  
Jelena Blagojevic ◽  
N. Vanis ◽  
B. Stanojevic ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Digestive Tract ◽  
Digestive System ◽  
Malignant Tumors ◽  
Blood Groups ◽  
Liver Carcinoma ◽  
Abo Blood Groups ◽  
Rhesus Factor ◽  
Clinical Center ◽  
Group B

The distribution of ABO blood groups and the Rhesus factor was analyzed in 279 patients who suffered from malignant tumors of the digestive system. Patients were registered retrospectively in the Gastroenterohepatology Clinic, Clinical Center, University of Sarajevo over a discontinuous period of 88 months. From the results obtained, it was concluded that: (a) men became ill from gastric cancer significantly more frequently than women; (b) the frequency of liver carcinoma was three times higher than the global frequency and the frequency neighboring ethnic groups; and (c) patients with blood group B and patients with RhD(-) exhibited a significantly higher proportion of disease.

scholarly journals Influence of the primary malignant tumor site on the incidence and features of metastatic ovarian tumors

2007 ◽  
Vol 64 (10) ◽  
pp. 691-696 ◽  
Author(s):  
Zorica Stanojevic ◽  
Biljana Djordjevic ◽  
Danijela Zivanovic
Keyword(s):  
Malignant Tumor ◽  
Malignant Tumors ◽  
Statistical Significance ◽  
Menopausal Status ◽  
Ovarian Tumors ◽  
Metastatic Tumors ◽  
Primary Tumors ◽  
Primary Malignant Tumor ◽  
Group A ◽  
Group B

Background/Aim. Ovary is the organ of the female reproductive system most commonly affected by metastases. The aim of the study was to determine the frequency and features of metastatic ovarian tumors (MOT) depending on the site of the primary malignant tumor. Methods. The study group consisted of 488 patients with histopathologically confirmed ovarian cancers treated at the Clinic of Oncology, Clinical Center Nis, in the period from 1 January 1998 to 31 December 2005. MOT were found in 41 patients. Regarding the site of the primary malignant tumor, those with secondary ovarian tumor were divided into two groups: group A - primary malignant tumor involving the genital organs (n = 30) and group B - primary malignant tumor of extragenital origin (n = 11). Results. MOT were confirmed in 8.40% (41/488) of the patients. Secondary ovarian malignancies were the consequence of endometrial carcinoma spreading in 73.17%, breast carcinoma in 19.51%, stomach carcinoma in 4.88% and colon carcinoma in 2.44% of the cases. No significant differences were found between the group A and group B by the factors of age, body mass index, parity and menopausal status. Contrary to the group A, metastatic tumors in the group B patients were more commonly asymptomatic (p < 0.001), bilateral (p < 0.05), with larger ovarian diameter (p < 0.05), associated with ascites (p < 0.001) and abdominal metastases (p < 0.01), all of statistical significance. Conclusions. Metastatic tumors made up 8.40% of ovarian neoplasmas. With non-genital primary tumors, secondary ovarian deposits were frequently asymptomatic, bilateral, associated with larger ovarian diameter, ascites and abdominal metastatic deposits, compared to malignant tumors of genital origin.

scholarly journals A Multicenter Epidemiological Study on Second Malignancy in Non-Syndromic Pheochromocytoma/Paraganglioma Patients in Italy

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5831
Author(s):  
Letizia Canu ◽  
Soraya Puglisi ◽  
Paola Berchialla ◽  
Giuseppina De Filpo ◽  
Francesca Brignardello ◽  
...  
Keyword(s):  
Malignant Tumor ◽  
Differentiated Thyroid Cancer ◽  
Genetic Test ◽  
Malignant Tumors ◽  
Multivariable Analysis ◽  
Second Malignancy ◽  
Standardized Incidence Ratio ◽  
Surveillance Strategy ◽  
Extensive Analysis ◽  
Second Tumor

No studies have carried out an extensive analysis of the possible association between non-syndromic pheochromocytomas and paragangliomas (PPGLs) and other malignancies. To assess the risk of additional malignancy in PPGL, we retrospectively evaluated 741 patients with PPGLs followed-up in twelve referral centers in Italy. Incidence of second malignant tumors was compared between this cohort and Italian patients with two subsequent malignancies. Among our patients, 95 (12.8%) developed a second malignant tumor, which were mainly prostate, colorectal and lung/bronchial cancers in males, breast cancer, differentiated thyroid cancer and melanoma in females. The standardized incidence ratio was 9.59 (95% CI 5.46–15.71) in males and 13.21 (95% CI 7.52–21.63) in females. At multivariable analysis, the risk of developing a second malignant tumor increased with age at diagnosis (HR 2.50, 95% CI 1.15–5.44, p = 0.021 for 50–59 vs. <50-year category; HR 3.46, 95% CI 1.67–7.15, p < 0.001 for >60- vs. <50-year). In patients with available genetic evaluation, a positive genetic test was inversely associated with the risk of developing a second tumor (HR 0.25, 95% CI 0.10–0.63, p = 0.003). In conclusion, PPGLs patients have higher incidence of additional malignant tumors compared to the general population who had a first malignancy, which could have an impact on the surveillance strategy.

scholarly journals A Review on the Research Progress of Inducible Nitric Oxide Synthase in the Pathogenesis of Pancreatic Malignancy

2021 ◽  
Vol 5 (4) ◽  
pp. 151-153
Author(s):  
Huimin Xiong ◽  
Ruiyao Wang ◽  
Chao Zhang
Keyword(s):  
Nitric Oxide ◽  
Pancreatic Cancer ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Digestive System ◽  
Malignant Tumors ◽  
Research Progress ◽  
Pancreatic Malignancy ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

Pancreatic cancer is a common tumor of the digestive system, at present, the pathogenesis is still unclear, but in the current research on the pathogenesis of pancreatic malignant tumors, the research on inducible nitric oxide synthase is particularly extensive. Therefore, this article focuses on the research progress of inducible nitric oxide synthase in the pathogenesis of pancreatic cancer. This is a review.

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