scholarly journals Analysis of Related Factors of Mother-to-Child Transmission of AIDS and Evaluation of Measures to Prevent Mother-to-Child Transmission

2022 ◽  
Vol 2022 ◽  
pp. 1-7
Author(s):  
Yuhuan Liu ◽  
Yulan Zhang ◽  
Lin Pang

AIDS is still a major public health facing the world. With the implementation of AIDS prevention projects and the continuous maturity of technology, more and more HIV-positive women choose to have children. However, the children born to these women are a special group. Exposure to HIV and antiviral drugs during the fetal period can increase the success rate of children’s elimination of the mother, which is worthy of attention and research. This article focuses on the analysis of the related factors of mother-to-child transmission of AIDS and the evaluation of mother-to-child blocking measures, using the method of field research to conduct experiments on AIDS patients in this city who are pregnant and provide them with antidrug treatment and some barrier measures. Then, the mother-to-child transmission rate was recorded, and the experimental results showed that the antidrug treatment plan is related to mother-to-child transmission. After antidrug treatment, the transmission rate of single-drug treatment is reduced by 5%, and the transmission rate of combined drug treatment is reduced by 10%. It can be seen from this that antidrug treatment is an effective measure to block mothers and babies.

2009 ◽  
Vol 1 (3) ◽  
pp. 29-32
Author(s):  
Ahmed Irfan ◽  
Muller Seiglinde ◽  
Saadeh Firas

ABSTRACT Aim A retrospective audit was conducted from 1st January 1996 to 31st December 2006 to assess the incidence of mother to child transmission of HIV and to assess changing trends over the last 10 years as well as the ethnicity of the patients. Methods All cases of HIV positive women delivered during the time period were considered. Age distribution, marital status women, parity, pregnancy planning, coinfection with Hepatitis B, Hepatitis C and Syphilis, gestational age at delivery, duration of rupture of membranes, mode of delivery and sex of the child were analyzed. Babies were followed up with HIV PCR at 6, 12 and 18 months. Results Of a total of 31 cases and 23 mothers, 3 cases were lost to follow-up. From the remaining 28 cases, only one infant tested HIV positive; hence, mother to child transmission rate was 3.6%. Of the 23 mothers, 22 (96%) are of African origin and 1 (4%) is ethnic irish. Most patients were primigravida or para 1. Conclusion The known correlation between the longer duration of rupture of membranes and the increased transmission of HIV was evident in the one case where mother to child transmission took place.


2010 ◽  
Vol 11 (2) ◽  
Author(s):  
Shakira M Cassim ◽  
Julia H Botha

The prevention of mother-to-child transmission (PMTCT) programme in the central region of Ethekweni Metro, KwaZulu-Natal (Durban central area), was investigated. Data for all HIV-exposed infants from eight private paediatric practices seen between January 2004 and June 2005 were reviewed retrospectively. One hundred and one black African infants were born to 100 HIV-positive women of average age 30 years. Median viral loads and CD4 counts were 11 391 copies/ml and 426 cells/μl, respectively. Eighty-six women received HAART and 5 had no prophylaxis. Of the 92 infants tested, 2 were HIV positive, giving a transmission rate of 2.2%. Both their mothers had received suboptimal prophylaxis, and if they are excluded, the transmission rate falls to less than 1%, a rate consistent with those in the developed world.


2009 ◽  
Vol 41 (2) ◽  
pp. 269-278 ◽  
Author(s):  
TIMOTHY ADAIR

SummaryIn Lesotho, the risk of mother-to-child-transmission (MTCT) of HIV is substantial; women of childbearing age have a high HIV prevalence rate (26·4%), low knowledge of HIV status and a total fertility rate of 3·5 births per woman. An effective means of preventing MTCT is to reduce unwanted fertility. This paper examines the unmet need for contraception to limit and space births among HIV-positive women in Lesotho aged 15–49 years, using the 2004 Lesotho Demographic and Health Survey. HIV-positive women have their need for contraception unmet in almost one-third of cases, and multivariate analysis reveals this unmet need is most likely amongst the poor and amongst those not approving of family planning. Urgent action is needed to lower the level of unmet need and reduce MTCT. A constructive strategy is to improve access to family planning for all women in Lesotho, irrespective of HIV status, and, more specifically, integrate family planning with MTCT prevention and voluntary counselling and testing services.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Siobhan Mark ◽  
Kellie E. Murphy ◽  
Stanley Read ◽  
Ari Bitnun ◽  
Mark H. Yudin

Objective. To evaluate whether the length of time of rupture of membranes (ROM) in optimally managed HIV-positive women on highly active antiretroviral therapy (HAART) with low viral loads (VL) is predictive of the risk of mother to child transmission (MTCT) of the human immunodeficiency virus (HIV).Study Methods. A retrospective case series of all HIV-positive women who delivered at two academic tertiary centers in Toronto, Canada from January 2000 to November 2010 was completed.Results. Two hundred and ten HIV-positive women with viral loads <1,000 copies/ml delivered during the study period. VL was undetectable (<50 copies/mL) for the majority of the women (167, 80%), and <1,000 copies/mL for all women. Mode of delivery was vaginal in 107 (51%) and cesarean in 103 (49%). The median length of time of ROM was 0.63 hours (range 0 to 77.87 hours) for the entire group and 2.56 hours (range 0 to 53.90 hours) for those who had a vaginal birth. Among women with undetectable VL, 90 (54%) had a vaginal birth and 77 (46%) had a cesarean birth. Among the women in this cohort there were no cases of MTCT of HIV.Conclusions. There was no association between duration of ROM or mode of delivery and MTCT in this cohort of 210 virally suppressed HIV-positive pregnant women.


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