Surgical Intervention to Treat Pharyngolaryngeal Stenosis Caused by Behcet’s Disease

We aimed to summarize the surgical treatment for pharyngolaryngeal stenosis and discuss prognosis in patients with Behcet’s disease. Six cases of pharyngolaryngeal stenosis caused by Behcet’s disease were analyzed retrospectively. All underwent surgical treatment for pharyngolaryngeal stenosis after systematic medical treatment. The follow-up time for the 6 patients was between 1 and 12 years. Four of the 6 patients underwent adhesiolysis as their first procedure. Two of these 4 experienced recurrence of stenosis within 6 months and underwent flap repair as their second procedure. The remaining two patients underwent flap reconstruction as their first procedure and maintained good swallowing function. Three of the 6 patients underwent preoperative tracheotomy because of dyspnea. Tracheal decannulation was successful in all patients. None of the patients experienced recurrence after their final surgical procedure and all recovered to a near-normal condition. Pharyngolaryngeal stenosis caused by Behcet’s disease is a rare but severe complication; surgical intervention should be considered in patients with dysphagia after systematic medical treatment.

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Surgical Treatment Result of Abdominal Aortic Aneurysm in Behçet’s Disease

Journal of Vascular Surgery ◽

10.1016/j.jvs.2007.12.023 ◽

2008 ◽

Vol 47 (2) ◽

pp. 481

Author(s):

T.-W. Kwon ◽

S.-J. Park ◽

H.-K. Kim ◽

H.-K. Yoon ◽

G.-E. Kim ◽

...

Keyword(s):

Abdominal Aortic Aneurysm ◽

Surgical Treatment ◽

Aortic Aneurysm ◽

Behçet’S Disease ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Treatment Result ◽

Behcet's Disease ◽

Abdominal Aortic

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P696 Long-term prognosis and predictive factors for surgical treatment of intestinal lesions in patients with Behcet’s disease

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jjy222.820 ◽

2019 ◽

Vol 13 (Supplement_1) ◽

pp. S468-S468

Author(s):

T Chohno ◽

K Watanabe ◽

T Minagawa ◽

R Kuwahara ◽

Y Horio ◽

...

Keyword(s):

Surgical Treatment ◽

Behçet’S Disease ◽

Predictive Factors ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Behcet's Disease ◽

Intestinal Lesions ◽

Long Term Prognosis

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Pediatric Behcet's Disease Patient with Cardiac Valvular Lesions: case report and a review of the literature

10.21203/rs.3.rs-1017088/v1 ◽

2021 ◽

Author(s):

Xin Yao ◽

Xin-Ning Wang ◽

Zhi-Xuan Zhou ◽

Sheng-Nan Li ◽

Jianming Lai

Keyword(s):

Surgical Treatment ◽

Behçet’S Disease ◽

Behcet’S Disease ◽

Cardiac Involvement ◽

Behçet's Disease ◽

Disease Patient ◽

Close Monitoring ◽

Primary Therapy ◽

Behcet's Disease ◽

Valvular Lesions

Abstract Background To explore the clinical characteristics, treatment regimen, and prognosis of cardiac valvular involvement in pediatric Behcet's disease. Methods Retrospective analysis was conducted on the clinical data obtained from one pediatric patient suffering from Behcet's disease with cardiac valvular involvement. Present study also reviewed the literature related to cardiac involvement in pediatric Behcet's disease. Results The disease onset in the female patient was reported at the age of 3 years, with clinical symptoms, including apthous ulcers, fever, perianal ulcers, and erythema nodosum, accompanied by a significant increase in the inflammatory markers. Echocardiography indicated that aortic valve (AV) lesions, which were absent initially, developed later, gradually exacerbated. Initially, she was diagnosed as "infectious disease" and "systemic inflammatory response syndrome", and antibiotic therapy proved ineffective. After an accurate diagnosis of Behcet's disease, the patient was given glucocorticoids, immunosuppressants, and biologics, which resulted in the relief of the symptoms; however, cardiac valvular lesions continued to exacerbate. Subsequent treatment included medical treatment and surgical treatment, and the patient's condition was stable at follow-up. Conclusions Cardiac valvular lesions in pediatric Behcet's disease are rare with insidious onset, enhancing the propensity of misdiagnosis or missed diagnosis. Main manifestations include recurrent oral ulceration, skin lesions, and fever. Cardiac involvement may occur early, yet the symptoms are insidious, requiring comprehensive physical examination and close monitoring of echocardiography. Glucocorticoids combined with immunosuppressants are the primary therapy for cardiac involvement in Behcet's disease. When cardiac valvular damage and dysfunction are observed, treatment regimens can be jointly recommended by multidisciplinary consultation to conduct the surgical treatment on time.

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Behçet’s disease: successful aortic root reconstruction in severely dilated aortoventricular junction after aortic valve replacement with novel surgical method – case report

Journal of Cardiothoracic Surgery ◽

10.1186/s13019-021-01467-1 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Miklós Pólos ◽

Ádám Koppányi ◽

Kálmán Benke ◽

László Daróczi ◽

Attila Oláh ◽

...

Keyword(s):

Surgical Treatment ◽

Aortic Valve ◽

Aortic Valve Replacement ◽

Valve Replacement ◽

Behçet’S Disease ◽

Aortic Root ◽

Behcet’S Disease ◽

Behçet's Disease ◽

Left Ventricular ◽

Behcet's Disease

Abstract Background Behçet’s disease is an auto-inflammatory disorder categorized as a primer systemic vasculitis of unknown aetiology. Genetic factors, infectious agents and the irregularity of T-cell homeostasis are presumed to be responsible for the emergence of Behçet’s disease. Characteristic symptoms are multisystemic. Although cardiovascular involvement is rare, it should be noted due to the difficulty of surgical treatment options. Case presentation Our 44-year-old male patient underwent aortic valve replacement due to aortic regurgitation. At the 15-month follow-up, echocardiography showed detachment of the prosthetic valve and in the aortic root, multiple pseudo-aneurysms were identified. We performed an aortic root reconstruction with a Bentall procedure using a special „skirted” conduit to reduce strain in the suture line between the conduit and the extremely dilated left ventricular outflow tract. Conclusions The surgical treatment of cardiovascular manifestations of Behçet’s disease remains challenging. This new technique may be beneficial in well-selected cases where the annulus of the aorta is extremely dilated or annular tissue disorder is present.

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