scholarly journals Description of on-farm treatment compliance and risk factors for culling in sows

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Magnus R. Campler ◽  
Jeremiah L. Cox ◽  
Heather L. Walker ◽  
Andréia G. Arruda

Abstract Background In commercial pig farming, sick or injured sows are often treated by producers or hired staff. To date, limited quantitative data exists on treatment compliance and the possible effect on sow longevity post-treatment. The objective of the study was to quantify on-farm compliance of treatment selection, frequency, and dosage, as well as to investigate the association between body condition scores (BCS) and other sow-level factors on post-treatment cull risk. Results On-farm treatment records, including culling reason or reason of death up to 6 months post-treatment, production records and sow characteristics were obtained for 134 sows over an 8-week period. Treatment compliance was based on the accuracy of recorded treatments compared to the herd veterinarian’s established treatment guidelines. Univariable and multivariable logistic regression models including treatment reason, treatment compliance, BCS, parity, production stage and production metrics, were constructed to investigate associations between those variables and sow culling or death. This study found low compliance for on-farm sow treatment protocols, with only 22.4% (30/134) of the sows receiving correct and complete treatment during the duration of the study. No effect of individual treatment components (drug, dosage, or frequency) on sow culling was observed. A trend for an interaction between treatment compliance and BCS was found, and parity and number of piglets born alive were identified as predictors for sow maintenance in the herd. Conclusions On-farm sow treatment compliance was low, resulting in that approximately 80% of the enrolled sows were not treated according to existing guidelines. Non-compliance of treatment guidelines did not seem to affect the risk of culling in treated sows but may have prolonged any associated pain, recovery time and negatively impacted the sow welfare during that time period.

2021 ◽  
Author(s):  
Fredrike Bannink ◽  
Nicole Geschwind

Positive CBT integrates positive psychology and solution-focused brief therapy within a cognitive-behavioral framework. It focuses not on reducing what is wrong, but on building what's right. This fourth wave CBT, developed by Fredrike Bannink, is now being applied worldwide for various psychological disorders. An introductory chapter explores the three approaches incorporated in positive CBT. Next, the book presents research into the individual treatment protocol for use with clients with major depressive disorder by Nicole Geschwind and colleagues at Maastricht University. The last chapters describe two 8-session treatment protocols for positive CBT, one for use with individuals and one for use with groups. The treatment protocols provide therapists with a step-by-step guide on how to apply positive CBT with individual clients and in group therapy. This approach goes beyond symptom reduction and instead focuses on the client’s preferred future, on finding exceptions to problems and identifying competencies. Topics such as self-compassion, optimism, gratitude, and behavior maintenance are explored. In addition to the protocols, two workbooks for clients are available online for download by therapists.


CJEM ◽  
2015 ◽  
Vol 17 (6) ◽  
pp. 656-661 ◽  
Author(s):  
Steven A Skitch ◽  
Rahim Valani

ABSTRACTObjectiveDiabetes is the most common pediatric endocrine disorder, and diabetic ketoacidosis (DKA) is the leading cause of diabetes-related morbidity and mortality. This article reviews pediatric DKA treatment protocols from across Canada and identifies similarities and differences.MethodsPediatric tertiary centres in Canada were asked for a copy of their DKA treatment protocol. For each protocol, we collected information on the amount of initial fluid bolus, maintenance fluid rate, insulin infusion rate, potassium replacement, monitoring and adjustment for serum glucose, administration of bicarbonate, and treatment for cerebral edema.ResultsResponses were obtained from 13 sites. Treatment guidelines were consistent in their recommendations on timing and dosage of intravenous insulin, potassium replacement, monitoring and adjusting for serum glucose, and management of cerebral edema. Variability in treatment protocols was found chiefly in volume of initial fluid bolus (range: 5–20 mL/kg) and length of time boluses should be administered (20–120 min), maintenance fluid rates (based on weight or a 48-hr deficit), and the role of bicarbonate administration.ConclusionsThis is the first review of treatment protocols for pediatric DKA in Canada. It identified many common approaches but noted specific differences in fluid boluses, maintenance fluid rates, and bicarbonate administration. The extent of variation indicates the need for further study, as well as national guidelines that are evidence-based and consistent with best practices.


Author(s):  
CITRA FEBRIONY ◽  
PURWANTYASTUTI . ◽  
MEANALDI RASMIN ◽  
VIVIAN SOETIKNO

Objective: Appropriate tuberculosis (TB) treatment guidelines are one of the many factors that influence the success of TB treatment. The patient’sdrug supervisor is a functional role that is part of the directly observed treatment short course, a program to support the success of TB treatment.The aim of this study was to analyze the TB treatment suitability in a community health center and the benefit of treatment compliance supervisionby the patient’s designated drug supervisor.Methods: We conducted a cross-sectional study in the Community Health Center of Pademangan subdistrict, North Jakarta, involving 205 subjects toanalyze appropriate fixed-dose combination (FDC) anti-TB drug administration and an experimental study involving 23 control group TB patients and23 intervention group TB patients to assess the benefit of supervision by each patient’s drug supervisor.Results: The association of FDC anti-TB drug side effects with the success of TB treatment was not statistically significant (p=0.173). There wasan increase in drug supervisor knowledge of 8.6% in the intervention group and 13% in the control group. There was no statistically significantassociation between the knowledge of the drug supervisor and the 2nd month (p=0.575) and the 6th month of sputum treatment.Conclusion: Minor side effects of FDC anti-TB drug did not affect the success of TB treatment; therefore, treatment was continued if these adverseevents occurred. There were no correlations between the drug supervisor knowledge level with medication compliance or with sputum conversion(months 2 and 6).


2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e18010-e18010
Author(s):  
Tingting Zhang ◽  
Yuqin Song ◽  
Zhi Tao Ying ◽  
Lingyan Ping ◽  
Chen Zhang ◽  
...  

e18010 Background: To effectively assist lymphoma patients and their care-givers after their hospital discharge, a standard follow-up guideline for lymphoma patients was designed and encoded through a computer-interpret-able-guideline (CiG) engine and deployed through mobile-Web and mobile-Apps to ensure continuous care throughout the treatment and recovery processes. Methods: Scheduled tasks including ePRO questionnaires and requests for test results were sent for completion, and a virtual care management team was assigned to ensure compliance and respond to automatic triggered alerts. Attending oncologists also were given mobile-Apps to access the patients’ securely uploaded records and consult remotely to manage side-effects manifested after discharge. The out-of-hospital record management and care coordination enabled the adjustment of individual treatment plans and the optimization of clinical resources utilization. Results: During 2018, 1012 patients or their caregivers interacted with our team through the mobile platform after discharge. Out of these, 856 individual patients uploaded enough information to be initiated in the mobile follow-up program. Approximately 30% of these patients were Beijing residents while the rest came from all over China. Close to half of these patients had follow-up tests done in other 387 hospitals or 52 clinics. Based on ePRO questionnaires submitted, 218 patients had 616 side-effect-symptom alerts triggered and followed up, in addition to patient-initiated mobile consultation with their attending oncologists. Lab results especially white blood cell counts, platelet counts, and neutrophil counts, contributed to the majority of test alerts managed by our team. Analysis of the thousands anonymized questions identified clinical processes in need of optimization. A new patient education manual addressing frequently asked questions, and new processes such as chemo-regime scheduling were put in place. Conclusions: We have demonstrated the feasibility of a mobile-deployed care management process after discharge for lymphoma patients and their caregivers. We have initiated retrospective studies of impacts on our patients’ treatment compliance and quality of life. A randomized clinical trial in six cancer types assessing the value of such an approach is also under planning.


Author(s):  
Arun Nagrath ◽  
Garima Gupta ◽  
Shikha Seth ◽  
Ekta Singh ◽  
AS Mathur

ABSTRACT Objectives To evaluate the effect of low-dose mifepristone (25 mg) on symptomatic myoma in perimenoapausal women. Study design Prospective observational clinical trial. Materials and methods Ninety-three perimenopausal women of age 35 to 50 years having symptomatic myoma were selected from gynecology outpatient department and given 25 mg mifepristone once daily continuously for 3 months. Baseline uterine size, uterine volume, myoma size, volume, their number, position, characteristics, hemoglobin and blood parameters, were taken and followed monthly for 6 months. Bleeding and pain scores were checked on monthly visits. Change in above parameters were tabulated during the first 3 months treatment phase and then next 3 months post-treatment phase for analysis. Statistical analysis Done by calculating mean, standard deviation, standard error and percentage distribution of variables. Results Menorrhagia was the commonest symptom which led patients to report to hospital. Mean uterine volume reduced to 63.69% of baseline, mean dominant myoma volume reduced to 53.62% and hemoglobin level raised to 137% after complete treatment of 3 months. Changes persisted in next 3 months post-treatment follow-up, while hysterectomy was required in 10 (12.2%) cases. Conclusion Three months treatment of 25 mg mifepristone effectively controls bleeding, reduces the uterine and myoma volume and thus can avoid blood transfusion and hysterectomy in a lot of symptomatic myoma cases. How to cite this article Seth S, Singh E, Mathur AS, Gupta G, Nagrath A. Low-dose Mifepristone (25 mg) in Treatment of Uterine Myoma in Perimenopausal Women. J South Asian Feder Menopause Soc 2013;1(1):34-37.


PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11596 ◽  
Author(s):  
Pius S. Ekong ◽  
Essam M. Abdelfattah ◽  
Emmanuel Okello ◽  
Deniece R. Williams ◽  
Terry W. Lehenbauer ◽  
...  

Background Antimicrobial drugs (AMD) are critical for the treatment, control, and prevention of diseases in humans and food-animals. Good AMD stewardship practices and judicious use of AMD are beneficial to the preservation of animal and human health from antimicrobial resistance threat. This study reports on changes in AMD use and stewardship practices on California (CA) dairies, following the implementation of CA Senate Bill 27 (SB 27; codified as Food and Agricultural Code, FAC 14400–14408; here onward referred to as SB 27), by modeling the associations between management practices on CA conventional dairies and seven outcome variables relating to AMD use and stewardship practices following SB 27. Methods A survey questionnaire was mailed to 1,282 grade A licensed dairies in CA in spring of 2018. Responses from 132 conventional dairies from 16 counties were included for analyses. Multivariate logistic regression models were specified to explore the associations between survey factors and six outcome variables: producers’ familiarity with the Food and Drug Administration’s (FDA), Silver Spring, WA, USA medically important antimicrobial drugs (MIAD) term; change in over-the-counter (OTC) AMD use; initiation or increased use of alternatives to AMD; changes to prevent disease outbreaks; changes in AMD costs; and better animal health post SB 27. We employed machine learning classification models to determine which of the survey factors were the most important predictors of good-excellent AMD stewardship practices of CA conventional dairy producers. Results Having a valid veterinary-client-patient-relationship, involving a veterinarian in training employees on treatment protocols and decisions on AMDs used to treat sick cows, tracking milk and/or meat withdrawal intervals for treated cows, and participating in dairy quality assurance programs were positively associated with producers’ familiarity with MIADs. Use or increased use of alternatives to AMDs since 2018 was associated with decreased use of AMDs that were previously available OTC prior to SB 27. Important variables associated with good-excellent AMD stewardship knowledge by CA conventional dairy producers included having written or computerized animal health protocols, keeping a drug inventory log, awareness that use of MIADs required a prescription following implementation of SB 27, involving a veterinarian in AMD treatment duration determination, and using selective dry cow treatment. Conclusions Our study identified management factors associated with reported AMD use and antimicrobial stewardship practices on conventional dairies in CA within a year from implementation of SB 27. Producers will benefit from extension outreach efforts that incorporate the findings of this survey by further highlighting the significance of these management practices and encouraging those that are associated with judicious AMD use and stewardship practices on CA conventional dairies.


2018 ◽  
Author(s):  
Christopher A. Bail ◽  
Lisa Argyle ◽  
Taylor Brown ◽  
John Bumpuss ◽  
Haohan Chen ◽  
...  

There is mounting concern that social media sites contribute to political polarization by creating "echo chambers" that insulate people from opposing views about current events. We surveyed a large sample of Democrats and Republicans who visit Twitter at least three times each week about a range of social policy issues. One week later, we randomly assigned respondents to a treatment condition in which they were offered financial incentives to follow a Twitter bot for one month that exposed them to messages produced by elected officials, organizations, and other opinion leaders with opposing political ideologies. Respondents were re-surveyed at the end of the month to measure the effect of this treatment, and at regular intervals throughout the study period to monitor treatment compliance. We find that Republicans who followed a liberal Twitter bot became substantially more conservative post-treatment, and Democrats who followed a conservative Twitter bot became slightly more liberal post-treatment. These findings have important implications for the interdisciplinary literature on political polarization as well as the emerging field of computational social science.


2020 ◽  
Vol 2020 ◽  
pp. 1-35 ◽  
Author(s):  
Lucas Amaral-Machado ◽  
Wógenes N. Oliveira ◽  
Susiane S. Moreira-Oliveira ◽  
Daniel T. Pereira ◽  
Éverton N. Alencar ◽  
...  

Asthma, a disease classified as a chronic inflammatory disorder induced by airway inflammation, is triggered by a genetic predisposition or antigen sensitization. Drugs currently used as therapies present disadvantages such as high cost and side effects, which compromise the treatment compliance. Alternatively, traditional medicine has reported the use of natural products as alternative or complementary treatment. The aim of this review was to summarize the knowledge reported in the literature about the use of natural products for asthma treatment. The search strategy included scientific studies published between January 2006 and December 2017, using the keywords “asthma,” “treatment,” and “natural products.” The inclusion criteria were as follows: (i) studies that aimed at elucidating the antiasthmatic activity of natural-based compounds or extracts using laboratory experiments (in vitro and/or in vivo); and (ii) studies that suggested the use of natural products in asthma treatment by elucidation of its chemical composition. Studies that (i) did not report experimental data and (ii) manuscripts in languages other than English were excluded. Based on the findings from the literature search, aspects related to asthma physiopathology, epidemiology, and conventional treatment were discussed. Then, several studies reporting the effectiveness of natural products in the asthma treatment were presented, highlighting plants as the main source. Moreover, natural products from animals and microorganisms were also discussed and their high potential in the antiasthmatic therapy was emphasized. This review highlighted the importance of natural products as an alternative and/or complementary treatment source for asthma treatment, since they present reduced side effects and comparable effectiveness as the drugs currently used on treatment protocols.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 22-22
Author(s):  
Trevor DeVries

Abstract The dairy industry has an increasing availability of equipment that is readily available for the automation of management tasks, including milking and feeding, as well as the monitoring of dairy cow behavior. Such automation not only has the ability to improve production and time efficiency on farm, but also increases our ability to monitor individual cows. Rapid adoption of automated (robotic) milking systems (AMS) is a good example of such benefits. Producers who have adopted this technology suggest they gain more time flexibility, find work to be less stressful and physically demanding, and report improved quality of their own life as well as that of their cows. At the same time, adoption of AMS may be associated with improvements in cow health and productivity. Similar findings apply for the adoption of automated milk feeders for dairy calves. The adoption of automated milk feeders has been done in effort to provide higher milk allowances, and thus raise healthier and better growing calves, reduce labor, and improve working conditions on farm. While less studied, automation in feeding of lactating cows also holds much promise for improving feeding accuracy and precision; thus not only reducing labor needs, but also having positive effects on cow production and efficiency. Finally, there is also rapid adoption of automated technologies for individual behavioral monitoring of dairy cows. These technologies have widely been adopted for estrus detection. In addition, they are also useful for detection of health disorders, both in occurrence and in advance of clinical symptoms. This, in turn, allows producers to identify and implement prevention and treatment protocols at earlier time points. It is anticipated that in the future such behavioral monitoring will play a larger role in terms of informing management decisions on farm.


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