Subcutaneous Edema

2021 ◽  
pp. 275-280
Author(s):  
Wendy A. Ware ◽  
John D. Bonagura ◽  
Brian A. Scansen
Keyword(s):  
Subcutaneous Edema

scholarly journals Hepatic Inflammatory Myofibroblastic Tumor Detected in the Fetal Period That Caused an Oncologic Emergency

2020 ◽  
Vol 13 (3) ◽  
pp. 1513-1519
Author(s):  
Hirotaka Kato ◽  
Yasuyuki Mitani ◽  
Taro Goda ◽  
Masaki Ueno ◽  
Shinya Hayami ◽  
...  
Keyword(s):  
Inflammatory Myofibroblastic Tumor ◽  
Emergency Operation ◽  
Cystic Mass ◽  
Abdominal Distention ◽  
Tumor Biopsy ◽  
Emergency Cesarean ◽  
Subcutaneous Edema ◽  
Male Neonate ◽  
Circulation Dynamics ◽  
Inflammatory Effect

A huge abdominal cystic lesion with ascites was detected in a male neonate at 31 weeks of gestation. Increasing ascites and the appearance of subcutaneous edema were detected, which caused fetal hydrops. The patient was delivered by emergency cesarean section at 33 weeks of gestation. The birth weight was 2,407 g, and the Apgar score was 8/9 points (1-/5-min values). Breathing at birth was stable, but the patient presented with remarkable abdominal distention due to the ascites. Later, the patient presented with tachypnea, and breathing gradually worsened, so an emergency operation was performed. There were no intraoperative findings within the small intestine, but there was a large amount of ascites and a cystic mass arising from the liver. The patient’s breathing and circulation dynamics could only be stabilized by ascites removal, so only a tumor biopsy was performed. The pathological findings led to the diagnosis of an inflammatory myofibroblastic tumor, and steroids were administered early after surgery for the purpose of an anti-inflammatory effect and tumor shrinkage. The abdominal distention was alleviated, and blood examinations showed a reduced inflammatory response. There was no apparent shrinkage of the tumor, however; thus, radical surgical treatment was performed on day 24. The postoperative course was uneventful, so the patient was discharged on day 36. Seven years after the operation there has been no recurrence or distant metastasis.

scholarly journals Ultrasonographic Classification of Subcutaneous Edema Caused by Infusion via Peripheral Intravenous Catheter

2016 ◽  
Vol 24 (2) ◽  
pp. 60-65 ◽  
Author(s):  
Koichi Yabunaka ◽  
Ryoko Murayama ◽  
Hidenori Tanabe ◽  
Toshiaki Takahashi ◽  
Makoto Oe ◽  
...  
Keyword(s):  
Intravenous Catheter ◽  
Subcutaneous Edema ◽  
Peripheral Intravenous Catheter

scholarly journals Intravenous administration of anakinra in children with macrophage activation syndrome

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Omkar Phadke ◽  
Kelly Rouster-Stevens ◽  
Helen Giannopoulos ◽  
Shanmuganathan Chandrakasan ◽  
Sampath Prahalad
Keyword(s):  
Intravenous Administration ◽  
Lupus Erythematosus ◽  
Macrophage Activation Syndrome ◽  
Macrophage Activation ◽  
Therapeutic Option ◽  
Interleukin 1 ◽  
Neurological Dysfunction ◽  
Systemic Jia ◽  
Subcutaneous Edema ◽  
Activation Syndrome

Abstract Background Subcutaneous anakinra is an interleukin-1 inhibitor used to treat juvenile idiopathic arthritis. Recent reports suggest anakinra can be a valuable addition to the treatment of COVID-19 associated cytokine storm syndrome and the related multisystem inflammatory syndrome (MIS-C) in children. Herein, we describe our experience with intravenously administered anakinra. Findings 19 Patients (9 male) received intravenous (IV) anakinra for treatment of macrophage activation syndrome (MAS) secondary to systemic lupus erythematosus (SLE), systemic JIA (SJIA) or secondary hemophagocytic lymphohistiocytosis (sHLH). In most cases the general trend of the fibrinogen, ferritin, AST, and platelet count (Ravelli criteria) improved after initiation of IV anakinra. There were no reports of anaphylaxis or reactions associated with administration of IV anakinra. Conclusion Intravenous administration of anakinra is an important therapeutic option for critically ill patients with MAS/HLH. It is also beneficial for those with thrombocytopenia, subcutaneous edema, neurological dysfunction, or very young, hospitalized patients who need multiple painful subcutaneous injections.

scholarly journals Pasteurella Multocida tenosynovitis of the flexor pollicis longus caused by a rabbit bone wound

2020 ◽  
pp. 50-56
Author(s):  
Blasco Alejandro ◽  
Cuñat-Aragó Borja ◽  
Baixauli Emilio ◽  
Amaya-Valero Jose
Keyword(s):  
Emergency Department ◽  
Pasteurella Multocida ◽  
Oral Antibiotic ◽  
Flexor Pollicis Longus ◽  
Indication For Surgery ◽  
Subcutaneous Edema ◽  
Show Evidence ◽  
Amoxicillin Clavulanate ◽  
Limited Function ◽  
Rabbit Bone

A 29-year-old man was admitted to our emergency department with a painful thumb, feverredness, and swelling and limited function. Five days before he was wounded with a rabbitbone. He was given amoxicillin-clavulanate with a lack of improvement. He was admitted forhospitalization and an ultrasound confirmed tenosynovitis as well as subcutaneous edema, sosurgical debridement was performed. Cultures were positive to Pasteurella multocida.Hospital stay was 9 days, and he continued oral antibiotic for 10 days after discharge. Fourmonths postoperatively, the patient had complete function and didn’t show evidence ofrecurrence. To conclude, rapidly developing cellulitis, tenosynovitis, fever and drainage fromhand wounds after a cat or dog bites should suggest Pasteurella multocida infection.However, P. multocida tenosynovitis can be also produced after a rabbit bone wound.Absence of response after 24-48 of antibiotic treatment, especially if cellulitis has progressedto tenosynovitis, is an indication for surgery.

scholarly journals Poisoning of cattle by Senecio spp. in Brazil: a review

2018 ◽  
Vol 38 (8) ◽  
pp. 1459-1470 ◽  
Author(s):  
Welden Panziera ◽  
Saulo P. Pavarini ◽  
Luciana Sonne ◽  
Claudio S.L. Barros ◽  
David Driemeier
Keyword(s):  
Pyrrolizidine Alkaloids ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Extended Period ◽  
Southern Brazil ◽  
Adult Cattle ◽  
Toxic Principle ◽  
Neurological Signs ◽  
Subcutaneous Edema ◽  
High Concentrations

ABSTRACT: Poisoning of cattle by plants of the Senecio genus represents an important cause of death in cattle and has important economic repercussions in southern Brazil. This review is intended to provide a detailed review of Senecio spp. intoxication in cattle and addresses issues regarding the toxic principle and pathogenesis of the disease caused by these plants and the epidemiology, clinical signs, diagnosis, control and prophylaxis of the disease. Senecio brasiliensis is the main species associated with natural intoxication of livestock in Brazil, and the number of cases associated with the ingestion of S. madagascariensis is increasing. The toxic principle of Senecio spp. comprises the hepatotoxic alkaloids of the pyrrolizidine group (pyrrolizidine alkaloids, PAs). The resulting liver lesions are chronic and irreversible and result from the inhibition of hepatocellular mitosis. Deaths of adult cattle may occur both sporadically and in larger outbreaks over an extended period of time. In cattle raising, Senecio spp. are consumed mainly during the winter, when there is a dearth of forage; at this time the poisonous Senecio species are budding and contain high concentrations of PAs. Spontaneous Senecio spp. intoxication in cattle is a chronic condition that frequently involves acute clinical manifestations. Affected cattle may present ascites, emaciation, intermittent dark diarrhea, tenesmus, rectal prolapse, and neurological signs resulting from hepatic encephalopathy. Hepatogenous photosensitization may be observed but is uncommon. Necropsy findings include dependent subcutaneous edema, ascites, and edema of the mesentery, abomasal folds, and gallbladder. The liver is firm, normal or reduced in size with a white, thick capsule. Microscopically, the hallmarks of Senecio-associated disease are varying degrees of hepatocellular megalocytosis, bile duct hyperplasia and fibrosis. Sheep are significantly more resistant to Senecio intoxication than are cattle and avidly ingest Senecio plants; therefore, the use of sheep for grazing infested pasture is recommended for preventing the associated disease in cattle.

Combination of fluoride and endosulfan induced teratogenicity and developmental toxicity in Swiss albino mice exposed during organogenesis

2019 ◽  
Vol 35 (9) ◽  
pp. 604-613
Author(s):  
Anju Sharma ◽  
PJ John ◽  
Pradeep Bhatnagar
Keyword(s):  
Body Weight ◽  
Developmental Toxicity ◽  
Combination Group ◽  
Maternal Weight ◽  
Additive Interaction ◽  
Swiss Albino Mice ◽  
Skeletal Malformations ◽  
Subcutaneous Edema ◽  
Fetal Malformations ◽  
Albino Mice

The present investigation was conducted to evaluate the teratogenic and developmental toxicity of fluoride and endosulfan alone and in combination in pregnant Swiss albino mice exposed during the organogenetic period (5–14 days) of gestation. Fluoride (25.1 mg/kg body weight in water) and endosulfan (1.8 mg/kg bw by oral intubation) when administered alone and in combination (fluoride 25.1 mg/kg bw + endosulfan 1.8 mg/kg bw) to pregnant mice caused significant teratogenic effects in developing fetuses. There was no maternal mortality but significant decreases in maternal weight gain and numbers of live fetuses and significant increases in numbers of fetal resorption were recorded in the treated groups. The fetal body weight and litter size also decreased significantly in all treated groups. No external malformations were observed in any of the fetuses. The percent of visceral and skeletal anomalies increased in the fetuses of all treated groups. The fetal malformations observed were internal hydrocephaly, microphthalmia, anophthalmia, pulmonary edema, subcutaneous edema, reduced ossification of skull bones, widened cranial sutures, rib anomalies (short, wavy, partially ossified, or absent ribs), and reduced ossification of phalanges. The occurrence of visceral and skeletal malformations was more severe in the combination group, suggesting additive interaction of fluoride and endosulfan in inducing developmental toxicity in Swiss albino mice.

scholarly journals Systemic mastocytosis with subcutaneous hemorrhage and edema in a Greyhound dog: case report and review of diagnostic criteria

2020 ◽  
Vol 33 (1) ◽  
pp. 95-100
Author(s):  
Alexander Aceino ◽  
Unity Jeffery ◽  
Julie Piccione ◽  
Carolyn L. Hodo
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Diagnostic Criteria ◽  
Complete Blood Count ◽  
Systemic Mastocytosis ◽  
Mast Cell Tumors ◽  
Multiple Organs ◽  
Subcutaneous Edema ◽  
Diagnostic Framework ◽  
Criteria For Diagnosis

Systemic mastocytosis, characterized by infiltration of multiple organs by neoplastic mast cells, is a well-described entity in human medicine with specific criteria for diagnosis, but is ill defined in veterinary literature. Hemostatic disorders are reported in humans affected by systemic mastocytosis but have not been well described in veterinary literature. A 5-y-old, spayed female Greyhound dog had a 1-mo history of progressive ventral cutaneous edema, hemorrhage, and pain. Cytology of an antemortem aspirate from the subcutis of the ventral abdomen was suggestive of mast cell neoplasia, but no discrete mass was present. The dog was euthanized and submitted for autopsy; marked subcutaneous edema and hemorrhage were confirmed. The ventral abdominal panniculus and dermis superficial to the panniculus carnosus were infiltrated by a dense sheet of neoplastic mast cells. The neoplastic cells contained toluidine blue–positive granules and formed aggregates within the bone marrow and several visceral organs, including the liver, spleen, heart, and kidney. Diffuse edema and hemorrhage is an unusual presentation of mast cell tumors in dogs. Antemortem tests, including complete blood count, coagulation profile, and viscoelastic coagulation testing, were suggestive of a primary hemostatic defect. We discuss here the diagnostic criteria used in humans, how these can be applied to veterinary patients, and the limitations of the current diagnostic framework.

scholarly journals When an incidental MRI finding becomes a clinical issue

2019 ◽  
Vol 132 (1-2) ◽  
pp. 27-34
Author(s):  
Ursula Schwarz-Nemec ◽  
Klaus M. Friedrich ◽  
Michael A. Arnoldner ◽  
Felix K. Schwarz ◽  
Michael Weber ◽  
...  
Keyword(s):  
Disc Degeneration ◽  
Facet Joint ◽  
Low Grade ◽  
Obese Patients ◽  
Joint Degeneration ◽  
Clinical Issue ◽  
Hepatic Diseases ◽  
Subcutaneous Edema ◽  
Facet Joint Degeneration ◽  
Magnetic Resonance Imaging Mri

Summary Background On magnetic resonance imaging (MRI), posterior lumbar subcutaneous edema (PLSE) is a frequent incidental, yet unclear finding within the deep subcutaneous perifascial tissue. This study aimed to investigate PLSE in various pathological lumbar conditions. Methods This retrospective study included the MR images of the lumbar spine of 279 patients (age range 18–82 years) without cardiovascular, renal or hepatic diseases, 79 of whom had low-grade disc degeneration, 101 combined endplate and facet joint degeneration, 53 axial spondyloarthritis and 46 infectious spondylodiscitis. There were 232 patients with a body mass index (BMI) <30, and 47 with a BMI ≥30 (obese). For each group, the relationship between PLSE and BMI was analyzed using multiple logistic regression, and between PLSE extension and BMI using ordinal regression. Results A PLSE was found in 11/79 (13.9%) patients with disc degeneration, 37/101 (36.6%) with endplate and facet joint degeneration, 7/53 (13.2%) with spondyloarthritis, and 28/46 (60.9%) with spondylodiscitis. For each group, a statistically significant relationship was demonstrated between PLSE and BMI (P = 0.000–P = 0.031), except for spondylodiscitis (P = 0.054), as well as between PLSE extension and BMI (P = 0.000–P = 0.049). A PLSE was found in 21.1% of nonobese and 72.3% of obese patients (P = 0.000). Conclusion The presence of PLSE seems to be associated with various lumbar conditions, particularly in obese patients. Its perifascial location may suggest a potential fascial origin; however, PLSE should not to be confused with posttraumatic, postsurgical or infectious edema or edema associated with internal diseases.

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