scholarly journals CD44 expression in the bile duct epithelium is related to hepatic fibrosis in nonalcoholic steatohepatitis rats induced by a choline-deficient, methionine-lowered, L-amino acid diet

Author(s):  
Kinuko UNO ◽  
Katsuhiro MIYAJIMA ◽  
Marika TOMA ◽  
Noriko SUZUKI-KEMURIYAMA ◽  
Dai NAKAE
1983 ◽  
Vol 31 (11) ◽  
pp. 1312-1316 ◽  
Author(s):  
P M Iannaccone ◽  
J Koizumi

Gamma-glutamyl transpeptidase (gamma-GTP), an amino acid transport enzyme, has been demonstrated in a number of fetal and adult tissues of rodent and man. While the re-expression of the enzyme has been described in epithelia following carcinogen treatment or aging, little is known of the mechanism of its disappearance in some neonatal tissues. A description is presented of the rate and pattern of loss of histologically demonstrable gamma-GTP activity from fetal and neonatal liver of the rat. The number of hepatocytes with histologically demonstrable gamma-GTP activity declines rapidly from the 18th day of gestation. By the 6th day postpartum the activity is demonstrable in clusters of hepatocytes. By the 7th day postpartum there are essentially no hepatocytes with demonstrable activity, although the enzyme remains expressed in bile duct epithelium.


1992 ◽  
Vol 27 (10) ◽  
pp. 845-851 ◽  
Author(s):  
T. Ohta ◽  
T. Nagakawa ◽  
Y. Tsukioka ◽  
H. Sanada ◽  
I. Miyazaki ◽  
...  

Hepatology ◽  
1998 ◽  
Vol 28 (3) ◽  
pp. 620-623 ◽  
Author(s):  
Koichi Tsuneyama ◽  
Mitsue Yasoshima ◽  
Kenichi Harada ◽  
Katsushi Hiramatsu ◽  
M. Eric Gershwin ◽  
...  

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