scholarly journals Comparison of Error Types and Qualitative Analysis of Correct Responses in a Confrontation Naming Test for Subtypes of Mild Cognitive Impairment

2017 ◽  
Vol 22 (3) ◽  
pp. 561-569
Author(s):  
Soo Ryon Kim
2008 ◽  
Vol 2 (3) ◽  
pp. 217-222 ◽  
Author(s):  
Indra F. Willers ◽  
Mónica L. Feldman ◽  
Ricardo F. Allegri

Abstract Mild cognitive impairment (MCI) is the transitional stage between normal aging and Alzheimer's disease (AD). Impairments in semantic memory have been demonstrated to be a critical factor in early AD. The Boston Naming Test (BNT) is a straightforward method of examining semantic or visuo-perceptual processing and therefore represents a potential diagnostic tool. The objective of this study was to examine naming ability and identify error types in patients with amnestic mild cognitive impairment (aMCI). Methods: Twenty aMCI patients, twenty AD patients and twenty-one normal controls, matched by age, sex and education level were evaluated. As part of a further neuropsychological evaluation, all subjects performed the BNT. A comprehensive classification of error types was devised in order to compare performance and ascertain semantic or perceptual origin of errors. Results: AD patients obtained significantly lower total scores on the BNT than aMCI patients and controls. aMCI patients did not obtain significant differences in total scores, but showed significantly higher semantic errors compared to controls. Conclusion: This study reveals that semantic processing is impaired during confrontation naming in aMCI.


2018 ◽  
Vol 23 (7) ◽  
pp. 840-850 ◽  
Author(s):  
Daruj Aniwattanapong ◽  
Sookjaroen Tangwongchai ◽  
Thitiporn Supasitthumrong ◽  
Solaphat Hemrunroj ◽  
Chavit Tunvirachaisakul ◽  
...  

2009 ◽  
Vol 15 (3) ◽  
pp. 407-415 ◽  
Author(s):  
STELLA KARANTZOULIS ◽  
ANGELA K. TROYER ◽  
JILL B. RICH

AbstractIndividuals with amnestic mild cognitive impairment (aMCI) often complain of difficulty remembering to carry out intended actions, consistent with findings of impaired prospective memory (PM) in this population. In this study, individuals with aMCI (N = 27) performed worse than healthy controls (N = 27) on the Memory for Intentions Screening Test (Raskin, 2004), including on time- and event-based subscales, and recognition of the intentions. The aMCI participants made more errors overall, but the proportion of the various error types did not differ between the two groups. Across all error types, both groups made more retrospective than prospective errors, especially on event-based PM tasks. Overall, the findings suggest that PM impairment in aMCI is associated with deficient cue detection involving both automatic (as in event-based tasks) and more strategic detection (as in time-based tasks) processes. These difficulties are likely due to a combination of problematic retrospective episodic memory (e.g., reduced encoding and/or consolidation of cue–intention pairings) and executive functions (e.g., decreased self-initiation, attention switching, and/or inhibition on memory tasks). Formal assessment of PM may help characterize the nature of the memory impairment among individuals with aMCI in clinical neuropsychological evaluations. (JINS, 2009, 15, 407–415.)


2019 ◽  
Vol 39 (1) ◽  
pp. 18-27
Author(s):  
Rina Mitsuto ◽  
Tsubasa Nishikoori ◽  
Kazumi Tatsukawa ◽  
Yukari Hashimoto ◽  
Makoto Miyatani

Author(s):  
Jung-Min Pyun ◽  
Nayoung Ryoo ◽  
Young Ho Park ◽  
SangYun Kim

<b><i>Background:</i></b> Fibrinogen is considered a marker of vascular pathology, indicating a weakened blood-brain barrier, and has a causative role in neuroinflammation and neurodegeneration. Little is known about the relationship between fibrinogen levels and cognitive function in patients with mild cognitive impairment (MCI). We aimed to investigate differences in cognitive profiles according to plasma fibrinogen levels in patients with MCI and the influence of plasma fibrinogen levels on cognitive decline. <b><i>Methods:</i></b> This retrospective cohort study included 643 patients with MCI: 323 patients in the high fibrinogen (high fib) group and 320 patients in the low fibrinogen (low fib) group. A multiple linear regression model was performed to compare cognitive test performance between groups. The Cox proportional hazard model was used to analyze the hazard ratio of fibrinogen level for disease progression. <b><i>Results:</i></b> The high fib group demonstrated poorer performance in attention, executive function, and confrontation naming than the low fib group. After adjustment for <i>APOE</i> genotype, the high fib group was associated with poor attention and executive function. After adjustment for vascular risk factors including body mass index, hypertension, diabetes mellitus, dyslipidemia, and smoking history, the high fib group showed declined attention and confrontation naming ability. High fibrinogen levels did not predict disease progression to CDR 1. <b><i>Conclusion:</i></b> High plasma fibrinogen levels were associated with poor performance in attention in patients with MCI, regardless of <i>APOE</i> genotype or vascular risk factors.


2021 ◽  
pp. 1-17
Author(s):  
Joseph A. Hirsch ◽  
George M. Cuesta ◽  
Pasquale Fonzetti ◽  
Joseph Comaty ◽  
Barry D. Jordan ◽  
...  

Background: Auditory naming tests are superior to visual confrontation naming tests in revealing word-finding difficulties in many neuropathological conditions. Objective: To delineate characteristics of auditory naming most likely to reveal anomia in patients with dementia, and possibly improve diagnostic utility, we evaluated a large sample of patients referred with memory impairment complaints. Methods: Patients with dementia (N = 733) or other cognitive impairments and normal individuals (N = 69) were evaluated for frequency of impairment on variables of the Auditory Naming Test (ANT) of Hamberger & Seidel versus the Boston Naming Test (BNT). Results: Naming impairment occurred more frequently using the ANT total score (φ= 0.41) or ANT tip-of-the tongue score (TOT; φ= 0.19) but not ANT mean response time compared to the BNT in patients with dementia (p <  0.001). Significantly more patients were impaired on ANT variables than on the BNT in Alzheimer’s disease (AD), vascular dementia (VaD), mixed AD/VaD, and multiple domain mild cognitive impairment (mMCI) but not in other dementias or amnestic MCI (aMCI). This differential performance of patients on auditory versus visual naming tasks was most pronounced in older, well-educated, male patients with the least cognitive impairment. Impaired verbal comprehension was not contributory. Inclusion of an ANT index score increased sensitivity in the dementia sample (92%). Poor specificity (41%) may be secondary to the inherent limitation of using the BNT as a control variable. Conclusion: The ANT index score adds diagnostic utility to the assessment of naming difficulties in patients with suspected dementia.


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