The reaction of the soft tissues of the anterior abdominal wall to various suture material

1982 ◽  
Vol 63 (4) ◽  
pp. 72-74
Author(s):  
V. P. Nefedov ◽  
R. M. Ramazanov

The healing processes of sutured wounds of soft tissues in most cases depend on the type and quality of the suture material. Any kind of suture material in the tissues of the body is a foreign body that causes various reactive changes from the tissues. The nature of these changes, all other things being equal, is mainly determined by the type of suture material, its thickness and the method of sterilization of the tissues on which the sutures are applied, the trauma of surgery, the infection of the wound and the irritating effect of the threads on the tissues.

2021 ◽  
Vol 11 (2) ◽  
pp. 212-215
Author(s):  
Mariya Zatolokina ◽  
Ekaterina Mishina ◽  
Alexander Sozykin ◽  
Marina Gorbunova ◽  
Alexander Alekseev

Background: The purpose of our work was determined by the accumulation of a significant amount of experimental material under the conditions of implantation of a foreign body, a mesh implant, into the region of the anterior abdominal wall in order to obtain experimental inflammation, in which foreign body giant cells (FBGCs) were constantly visualized as reactive formations. This research aimed to study the dynamics of morphological changes in FBGCs under conditions of experimental implantation of a foreign body, a mesh implant, and the possible mechanism of their formation Methods and Results: This study was carried out on male Wistar rats, in which a foreign body was implanted—a mesh endoprosthesis made of polypropylene—in the region of the anterior abdominal wall under the aponeurosis of the rectus abdominis muscles. A section of the anterior abdominal wall with the implanted endoprosthesis was excised on Days 10, 21, 30, and 60 after surgery, fixed in 10% buffered formalin solution. The obtained samples were embedded in paraffin according to standard prescriptions; histological sections with a thickness of 5-7µm were made and stained with H&E, according to the methods of Van Gieson and Mallory, and an immunohistochemical study was performed using the marker of cell proliferation (Ki-67). The revealed structural features of multinucleated cells were recorded by microphotography using a photo attachment and a Levenhuk video camera (USA). During the study, it was revealed that the amount, functional activity and morphological diversity of FBGCs gradually increased, reaching a maximum by Day 30 of the experiment. At a later date, some of them died, while the remaining part was differentiated, splitting into small multinucleated cells and mononuclear elements, morphologically identical to macrophages and fibroblasts. The formation of FBGCs continued as long as the mesh implant was in the body. Conclusion: FBGCs are reactive formations that arise in response to various endo- and exogenous irritation.


2018 ◽  
Vol 17 (3) ◽  
pp. 35-44 ◽  
Author(s):  
E. N. Degovtsov ◽  
P. V. Kolyadko ◽  
V. P. Kolyadko ◽  
A. V. Satinov

Objectives. To evaluate the immediate results of surgical treatment of patients with large incisional hernia of the anterior abdominal wall with the use of the mesh implants.Materials and methods. The data were retrospectively collected and analyzed. The study included patients with a large and / or complex incisional hernia. There were 108 patients who underwent incisional hernia repair with mesh reinforcement in the period from 2012 to 2016. In all cases the repairs were made with mesh implants. The average age of patients was (56.4 ± 10.4) years. The body mass index (BMI) was on average (32.6 ± 6.24) kg/m2. The medial localization of the hernia was 102 (94.44%). The width of the hernia defect averaged (12.2 ± 3.7) cm. Implants were placement in onlay positions – 19 (17.6%), sublay – 49 (45.37%), IPOM (Intraperitoneal onlay mesh) – 30 (27.77%) patients, the component separation technique (CST) with mesh reinforcement was used in 10 (9.25%) patients. Active aspiration drainage was performed in 72 (66.66%) patients.Results. The average time for draining the postoperative wound was (5 ± 2.2) days. The number of wound complications was 23 (21.3%), the number of seromas of the postoperative wound prevailed was 16 (14.8%) patients, of which 2 (1.85%) were chronic abdominal wall seromas, hematoma occurred in  2 patients (1.85%), the number of prolonged serous exudation was 7 (6.5%), necrosis of the wound edges occurred in 4 (3.7%) patients. There was no mortality. Reliably more often wound complications occurred in patients with large hernia defects (p = 0.006), and also with an increase in the duration of surgical intervention (p = 0.01). The hospital-stay in patients with complications was significantly greater (p < 0.001), the need for analgesics also increased (p < 0.001).Conclusion. Prevention of wound complications after large and complex incisional hernia repair with mesh reinforcement is an important direction in improving the results of surgical treatment in this category of patients.


Author(s):  
V.S. Drabovsky

Investigating life quality is remaining high in the context of healthcare reforming processes and in modern medicine. An increase in the number of surgical operations for cosmetic defects of the anterior abdominal wall, an increase in the requirements for treatment results, forced surgeons to look for alternative methods of treatment that would significantly reduce aesthetic defects and improve the quality of life by examining the effect of surgical treatment on the mental and physical components of health. This predetermined the purpose of this study. To achieve the goal, the results of a comprehensive clinical examination and correction of 81 patients with cosmetic defects of the anterior abdominal wall, who took the treatment at the clinic of the Department of Surgery No. 3, Ukrainian Medical Stomatological Academy, from 2012 – 2019, were analyzed. The main group (41) was operated on by using the biomechanical methods of abdominoplasty worked up by the author, taking into account the best angle of direction of the stress vectors in the tissue of the upper transverse skin-fat flaps in the postoperative period during stress relaxation. The comparison group consisted of 40 people operated on by standard techniques of mobilization and fixation of skin-fat flaps. Quality of life was assessed the day before the operation and 6 months after, according to the EUROQol-5S-5D questionnaire system. Based on the analysis of the results, the following conclusions have been drawn: surgical correction of cosmetic defects of anterior abdominal wall causes psycho-emotional and physiological prerequisites for growing physical activity of patients, and in 6 months in positively effects the self-assessment of patients’ health status. Overweight patients demonstrate a statistically significant decrease in body mass index during the year, which is inversely correlated with an improvement in the scores on the rating scale and a weak correlation with a change in the average scoring and self-assessment of body weight. This integrated technique for performing abdominoplasty in patients with cosmetic defects of the anterior abdominal wall has been proven as effective means, which can improve the quality of life of surgical patients.


2017 ◽  
Vol 07 (01) ◽  
pp. 078-079
Author(s):  
Likith Rai ◽  
Amol Dilip Amonkar

AbstractSoft-tissue metastasis refers to the growth of cancer cells originating from internal cancer in the soft tissues. In most cases, soft-tissue metastasis develops after initial diagnosis of the primary internal malignancy and late in the course of the disease. In very rare cases, they may occur at the same time or before the primary cancer has been detected. In our case, the soft-tissue metastasis and the primary lung cancer were diagnosed at the same time. To the best of our knowledge soft tissue metastasis on the anterior abdominal wall of unknown primary lung cancer is an extremely rare condition and only a handful of cases have been reported till date .We report a case of unsuspected soft tissue metastasis on the anterior abdominal wall of an unknown primary lung cancer with relevant discussion on the same.


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