scholarly journals Parapharyngeal Space Pleomorphic Adenoma: Common Tumour Type at an Uncommon Site

2021 ◽  
Vol 8 (1) ◽  
pp. 21-XX
Author(s):  
Shalina Kaur ◽  
Noor Dina Hashim ◽  
Afiza Izura M Mohammad Sofi ◽  
Gurdev Singh Naraman Singh ◽  
Khairil Amir Sayuti

Pleomorphic adenoma provides as much as 40-70% of tumors in the minor salivary gland with the palate being the most frequent area engaged. Head and neck tumors in parapharyngeal space amount to less than 1%. We share a case of pleomorphic adenoma primarily arising in parapharyngeal space. This report highlights clinical features, pathology, radiological findings, and treatment of this tumor.

2016 ◽  
Vol 8 (3) ◽  
pp. 125-127
Author(s):  
Ankita Joshi ◽  
Chinmaya Sundar Ray

ABSTRACT Parapharyngeal space (PPS) lesions account for only 0.5% head and neck tumors and the majority of the minor salivary gland tumors are malignant. We report a case of pleomorphic adenoma of minor salivary gland in PPS as this is of a very rare occurrence. High index of suspicion and an adequate clearance of the tumor with a cuff of surrounding dispensable normal tissues are the key to successful treatment of such tumors. How to cite this article Ray CS, Joshi A. Primary Pleomorphic Adenoma of Minor Salivary Gland in the Parapharyngeal Space. Int J Otorhinolaryngol Clin 2016;8(3):125-127.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Digvijay Singh Rawat ◽  
Divij Sonkhya ◽  
Nishi Sonkhya ◽  
Shubha Gupta

Parapharyngeal space tumors are rare and constitute only 0.5–1.0% of head and neck tumors. Minor salivary gland tumor is still rare in parapharyngeal space. We are reporting a case of pleomorphic adenoma of minor salivary gland of parapharyngeal space. A 42-year-old female presented with a history of mass in the oropharynx for 3 years. She presented with “hot potato voice” and dysphagia. CECT and MRI were done, showing large parapharyngeal space tumor. FNAC was suspicious for tumor of nerve cell origin. Tumor was excised using “paramedian mandibulotomy with mandibular swing approach”. Histopathological examination was inconclusive, suggesting possibility of extraskeletal myxoid chondrosarcoma, solitary fibrous tumor, neurogenic tumor. On immunohistochemistry, tumor was positive for cytokeratin, EMA (dim), S-100, and P 63 and negative for SMA thus proving the case as myoepithelial cell-rich pleomorphic adenoma.


2017 ◽  
Vol 6 (1) ◽  
pp. 159-162
Author(s):  
Punam Prasad Bhadani ◽  
◽  
Iffat Jamal ◽  
Suryakant Nirala ◽  
◽  
...  

2015 ◽  
Vol 03 (01) ◽  
pp. 047-050
Author(s):  
Gourav Ahuja ◽  
Jaideep Marya ◽  
Poonam Sood

AbstractSalivary gland tumors account for less than 3% of the head and neck tumors. Among various salivary gland tumors, pleomorphic adenoma is most common and accounts for 60- 70% of the benign tumors of salivary glands. However, the involvement of minor salivary glands of buccal mucosa is extremely uncommon and reported to be 4% only. Salivary glands may present with a diverse range of lesions presenting a challenge to even the most experienced clinician. We report two rare cases of pleomorphic adenoma of minor salivary glands of buccal mucosa in a 45 year old female and 70 years old male respectively. It includes clinical features, diagnosis and treatment of the tumor.


2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Serdal Celik ◽  
Osman Kilic ◽  
Tulay Zenginkinet ◽  
M. Tayyar Kalcioglu

Salivary gland tumors are rare among all head and neck tumors. Pleomorphic adenoma (PA) is the most commonly seen subtype, and 85% of the cases are located in the parotid gland. PA may very rarely be seen in minor salivary glands. Minor salivary gland PAs are mostly located in the hard and soft palates. Nasopharyngeal PA is very rare, and a total of 8 cases have been published to date. In this case report, a 51-year-old female patient who had nasopharyngeal PA with chondroid metaplasia is presented, and we review the relevant literature.


2015 ◽  
Vol 139 (1) ◽  
pp. 55-66 ◽  
Author(s):  
Shaobo Zhu ◽  
Conrad Schuerch ◽  
Jennifer Hunt

Context Immunohistochemistry is a useful tool for diagnosing salivary gland and head and neck tumors. Objective To review immunohistochemical markers, which can aid in the diagnosis of selected salivary gland and head and neck tumors. Data Sources Literature review and authors' personal practice experience. Conclusions Salivary gland and head and neck tumors include a large diverse group of tumors with complex and overlapping histologic features. Immunohistochemistry plays an important role in resolving the differential diagnosis of some salivary gland and head and neck tumors and can provide information for the prognosis of certain tumors.


2013 ◽  
Vol 28 (1) ◽  
pp. 24-27
Author(s):  
Sudipta Pal ◽  
Sampurna Pati ◽  
Somnath Saha ◽  
Vedula Padmini Saha

Objective: To present a case of carcinoma ex pleomorphic adenoma in the parapharyngeal space and discuss its management.   Methods: Design:            Case Report Setting:           Tertiary Government Teaching Hospital Subjects:         One   Results:  A 40-year-old male patient with dysphagia for three months and a left-sided mucosa-covered oropharyngeal mass was found to have a prestyloid parapharyngeal lesion on CT Scans. Fine Needle Aspiration Cytology (FNAC) revealed a pleomorphic adenoma. With a past history of parapharyngeal pleomorphic adenoma excised transorally three years before, the present mass was excised by mandibular swing approach. Post-operative recovery was uneventful, but the final histopathological report was carcinoma ex pleomorphic adenoma.   Conclusion: Malignant transformation should be suspected in recurrent salivary tumors in the parapharyngeal space. Provided there was truly no pre-existing malignant focus in the originally-excised tumor, and that early recurrence was not due to inadequate initial excision, this patient had a rare condition where the same tumor underwent malignant transformation within 3 years only. To the best of our knowledge, such an early transformation to malignancy of a minor salivary gland tumor of the parapharyngeal space has not been reported in the English literature.   Keywords: carcinoma ex pleomorphic adenoma, pleomorphic adenoma, carcinoma,  parapharyngeal space, malignant, transformation, minor salivary gland tumor,  mandibular swing


Author(s):  
Ramesh Kadela ◽  
Sonia Jindal ◽  
Pooja Arya ◽  
Niranjan Nagaraj ◽  
Deepchand Lal ◽  
...  

<p class="abstract">Parapharyngeal space tumors represent only 0.5% of all head and neck tumors. Out of which, 80% are benign and 20% are malignant. Tumor must be at least 2 cm in size before bulge or abnormality is palpable. We report a case of 8 year old female child who presented with bulge in right tonsillar region. </p>


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