scholarly journals Correlation Between Lipid Profile and Kidney Function in Ambulatory Heart Failure Patient

2021 ◽  
Vol 22 (1) ◽  
pp. 1-5
Author(s):  
Sidhi Laksono Purwowiyoto ◽  
Hengkie Frankie Lasanudin ◽  
Budhi Setianto ◽  
Steven Philip Surya ◽  
Wincent Candra Diwirya
Keyword(s):  
Heart Failure ◽  
Serum Creatinine ◽  
Lipid Profile ◽  
Kidney Function ◽  
Outpatient Setting ◽  
Study Data ◽  
Blood Cholesterol ◽  
Cross Sectional ◽  
Cholesterol Ratio ◽  
Heart Failure Patients

Heart failure contributes to a high number of hospitalizations. Currently, the number of outpatients is more dominant than hospitalized heart failure patients. Unfortunately, a study in the outpatient setting is still limited. This study aims to evaluate the correlation between lipid profile and kidney function in ambulatory heart failure patients. This study is a single-center cross-sectional study. Data were collected from August to September 2020. Data were extracted from 62 medical records of heart failure patients with ejection fraction 45%. Exclusion criteria were life-threatening comorbidity and patient with routine hemodialysis. Data were analyzed with Pearson or Spearman correlation test. Most of the heart failure patients in our outpatient clinic are elderly (60 years old) and male (58%). The researchers found positive correlation of total cholesterol (r 0.39; p 0.001) and triglyceride (r 0.59; p 0.001) to serum creatinine. On the other hand, LDL and blood cholesterol ratio negatively correlated with serum creatinine, r - 0.31; p 0.016; and r - 0.46; p 0.001; respectively. All of this analysis was statistically significant. It concluded that lipid profiles were correlated with kidney function in heart failure patients

scholarly journals Glomerular function in relation to fine airborne particulate matter in a representative population sample

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ying-Mei Feng ◽  
Lutgarde Thijs ◽  
Zhen-Yu Zhang ◽  
Esmée M. Bijnens ◽  
Wen-Yi Yang ◽  
...  
Keyword(s):  
Serum Creatinine ◽  
Population Sample ◽  
Airborne Particulate Matter ◽  
Blood Stream ◽  
Renal Outcome ◽  
Cross Sectional ◽  
Cholesterol Ratio ◽  
Median Serum ◽  
Renal Responses

AbstractFrom 1990 until 2017, global air-pollution related mortality increased by 40%. Few studies addressed the renal responses to ultrafine particulate [≤ 2.5 µm (PM2.5)], including black carbon (BC), which penetrate into the blood stream. In a Flemish population study, glomerular filtration estimated from serum creatinine (eGFR) and the urinary albumin-to-creatinine ratio were measured in 2005–2009 in 820 participants (women, 50.7%; age, 51.1 years) with follow-up of 523 after 4.7 years (median). Serum creatinine, eGFR, chronic kidney disease (eGFR < 60 mL/min/1.73 m2) and microalbuminuria (> 3.5/> 2.5 mg per mmol creatinine in women/men) were correlated in individual participants via their residential address with PM2.5 [median 13.1 (range 0.3–2.9) μg/m3] and BC [1.1 (0.3–18) μg/m3], using mixed models accounting for address clusters. Cross-sectional and longitudinally, no renal outcome was associated with PM2.5 or BC in models adjusted for sex and baseline or time varying covariables, including age, blood pressure, heart rate, body mass index, plasma glucose, the total-to-HDL serum cholesterol ratio, alcohol intake, smoking, physical activity, socioeconomic class, and antihypertensive treatment. The subject-level geocorrelations of eGFR change with to BC and PM2.5 were 0.13 and 0.02, respectively (P ≥ 0.68). In conclusion, in a population with moderate exposure, renal function was unrelated to ultrafine particulate.

scholarly journals Perawatan Diri Pada Pasien Gagal Jantung

2018 ◽  
Vol 4 (2) ◽  
Author(s):  
Dwi Prihatiningsih ◽  
Tiwi Sudyasih
Keyword(s):  
Heart Failure ◽  
Care Management ◽  
Financial Burden ◽  
Self Care ◽  
Chi Square ◽  
Cross Sectional ◽  
Low Frequencies ◽  
Heart Failure Patients ◽  
Failure Index ◽  
Care Behavior

ABSTRAKGagal jantung merupakan salah satu penyakit kardiovaskuler yang paling sering terjadi di seluruh dunia yang mengakibatkan tingginya angka mortalitas, morbiditas dan juga berdampak secara finansial terutama bagi lanjut usia. Rehospitalisasi merupakan masalah umum yang sering terjadi pada pasien gagal jantung yang sebagain besar disebabkan oleh keterlambatan dalam pengenalan gejala, pengobatan dan ketidakpatuhan diet serta kurangnya pengetahuan dan keterampilan dalam melakukan perawatan diri. Panduan penanganan gagal jantung menekankan pentingnya perilaku perawatan diri untuk menurunkan kekambuhan dan rehospitalisasi pada pasien gagal jantung. Penelitian ini bertujuan untuk menggambarkan perilaku perawatan diri pada pasien gagal jantung yang mengunjungi poliklinik jantung di RSUD Panembahan Senopati Bantul. Penelitian ini merupakan penelitian deskriptif quantitatif dengan menggunakan pendekatan cross sectional. Sampel berjumlah 74 responden yang merupakan pasien rawat jalan di poliklinik jantung pada bulan Juni hingga Juli 2018. Alat ukur yang digunakan adalah Self-Care of Heart Failure Index (SCHFI), (skor ≥70 poin=adekuat). Uji statistik chi-square digunakan untuk mengetahui hubungan antara factor sosiodemografi dengan perilaku perawatan diri pada pasien gagal jantung. Hasil penelitian ini menunjukkan bahwa perilaku perawatan diri pada sebagian besar responden masih belum adekuat dengan frekuensi perilaku perawatan diri adekuat yang masih rendah (pemeliharaan: 45±13.1 (7.7%), pengelolaan: 46±20.4 (13.0%) dan kepercayaan: 69±16.5 (38.5%)). Hanya satu faktor yaitu penyakit penyerta yang berhubungan dengan perilaku perawatan diri pada pasien gagal jantung pada dimensi kepercayaan diri. Hasil penelitian ini menunjukkan bahwa sebagian besar responden memiliki perilaku perawatan diri yang tidak adekuat seperti juga pada negara-negara lainnya sehingga diperlukan upaya untuk meningkatkan perilaku perawatan diri pada pasien gagal jantung. ABSTRACTHeart failure (HF) is one of the most prevalent cardiovascular diseases in the world which associated with significant mortality, morbidity, and huge financial burden, particularly among aging population. Rehospitalization remain a concern in the care of the heart failure patient which largerly associated with delay in symptoms recognition, treatment, diet non-compliance and also lack of knowledge and skills in heart failure self-care. Guideline on HF emphasize the important of self care in preventing symptoms and hospital readmission. This study aims to describe self-care behavior in a sample of heart failure patients. This is a descriptive cross-sectional study with non-probabilistic sample of 74 in an out-patient heart clinic from June-July 2018. Self-care was measured using the Self-Care of Heart Failure Index (SCHFI), (scores ≥70 points=adequate self-care). Chi-square test was conducted to test whether participant’s characteristics associated with self-care behavior among heart failure patients in three scales. The result shows that self-care was inadequate in most scales (self-care maintenance: 43.4±11.8, self-care management: 49.4±18.5 and self-care confidence: 68,6±14.5. Low frequencies of participants with adequate self-care also observed in the study (self-care maintenance: 5.4%, self-care management: 15.4%) and self-care confidence: 36.5%)). In self-care confidence subscale, higher scores of the SCHFI were associated with no comorbid conditions (p=0.01). None of the sociodemographic and clinical characteristics of the sample were associated with increased self-care in other 2 sub-scales. In conclusion, study shows that self-care in HF is inadequate, interventions aimed at improving self-care espescially in self-care maintenance sub-scale are greatly needed. Additional studies are needed to determine the best approach for this. 

scholarly journals Frequency of Diabetes and Prediabetes in Heart Failure Patients and Their Association with In-Hospital Outcome

2014 ◽  
Vol 13 (1) ◽  
pp. 1-6
Author(s):  
Noortaj Begum ◽  
Abu Sadique Abdullah ◽  
Md. Aminul Haque Khan ◽  
AN Wahida Sultana ◽  
DMMF Osmany ◽  
...  
Keyword(s):  
Heart Failure ◽  
Hospital Admissions ◽  
Length Of Hospital Stay ◽  
Tolerance Test ◽  
Oral Glucose ◽  
College Hospital ◽  
Cross Sectional ◽  
Impaired Fasting Glycaemia ◽  
Heart Failure Patients ◽  
Diagnosed Diabetes

Background: There are an increasing number of hospital admissions due to heart failure with diabetes or prediabetes in different hospitals in Bangladesh. But very little is known about the frequency of diabetes and prediabetes and the effect of its presence on the characteristics and outcome in patients hospitalized for heart failure. The objective of this study was to find out the frequency of diabetes and prediabetes in heart failure patients and to assess their association with in-hospital outcome.Methods: This cross sectional analytical study was done in the department of Biochemistry and Cardiology of Bangabandhu Sheikh Mujib Medical University in collaboration with department of Cardiology of National Institute of Cardiovascular Diseases, and Dhaka Medical College Hospital from July 2010 to June 2011. After proper ethical consideration a total two hundred and fifty heart failure patients were enrolled in the study by nonrandom sampling. Fasting blood sugar was done in all patients and oral glucose tolerance test was done in patients with impaired fasting glycaemia. Results: The frequency of prediabetes among the total population was 12.8% (95% CI, 8.7-16.8) and that of diabetes was 37.2% (95% CI, 31.2-43.2%). Improvement was achieved in 27 (84.4%) cases in prediabetic group, 75 (80.6%) cases in diabetic group and 105 (84.0%) cases in nondiabetic group. Mortality rates in prediabetes, diabetes and nondiabetes were 5 (15.6%); 18 (19.4%) and 20 (16.0%) respectively. The differences found among the three groups were not statistically significant (p>0.05). Length of hospital stay was also similar in all groups of study subjects. Conclusion: Frequency of diabetes among heart failure patients is high and pre-diabetes is not negligible in our country. Future studies in this field should focus on all types of glucose abnormalities rather than previously diagnosed diabetes only.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i1.19409

Study on Heart Failure Patients Admitted in National Institute of Cardiovascular Diseases

2021 ◽  
Vol 13 (2) ◽  
pp. 172-176
Author(s):  
Nur Alam ◽  
Abdullah Al Shafi Majumder
Keyword(s):  
Heart Failure ◽  
Acute Coronary Syndrome ◽  
Heart Disease ◽  
Cardiovascular Diseases ◽  
Epidemiological Studies ◽  
Clinical Syndrome ◽  
Cross Sectional ◽  
Common Cause ◽  
Heart Failure Patients ◽  
Coronary Syndrome

Background: Heart failure is a complex clinical syndrome that arises secondary to abnormalities of cardiac structure and/or function (inherited or acquired) that impair the ability of the left ventricle to fill or eject blood. There is a paucity of data on characteristics of the patients of heart failure admitted in hospitals in terms of demographic and etiological information. So, this study aimed to see the disease burden of heart failure patients and the age and sex specific prevalence of heart failure among patients admitted into NICVD and to identify the etiological pattern of diseases leading to heart failure with associated comorbid factors. Methods: It was a cross sectional study carried out at National Institute of Cardiovascular Diseases (NICVD) Dhaka Bangladesh and was conducted from January 2015 to December 2015. Total 400 heart failure patients were taken. Results: The mean age of the patients were 54 ± 14 years ranging from 16 to 95 years with a high preponderance of male. Most the patient population was in the age group of 51- 60 years (29.5%). 79% of the cases were male & 21% female by gender specification. Ischaemic cardiomyopathy (ICM) was found to be the common cause of heart failure (n=153, 40.75%) followed by Acute coronary syndrome (32.5%) and Valvular heart disease (18.25%). The patients with heart failure having acute coronary syndrome (n=107) had hypertension (46.8%) as the most prevalent major risk factor. In the present study only 11% patient had heart failure with preserved ejection fraction. Mortality rate of the study population were 6.3%. Conclusion: In this study, the most common cause of heart failure is ischaemic heart disease. So, patients of acute and chronic ischemic heart disease patients should be treated and follow up with care. Clinical and epidemiological studies are needed to explore further. Cardiovasc. j. 2021; 13(2): 172-176

Frequency of Atrial Fibrillation in Heart Failure Patients

2021 ◽  
Vol 15 (11) ◽  
pp. 3261-3264
Author(s):  
Syed Mohammad Haleem ◽  
Muhammad Hashim Kalwar ◽  
Muhammad Hassan Butt ◽  
Jehangir Hasan ◽  
Javed Khurshed Shaikh ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Demographic Data ◽  
Treatment Options ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Heart Failure Patients ◽  
Cardiac Symptoms ◽  
Patients With Heart Failure

Background: An increasing number of people around the world suffer from cardiovascular diseases such as atrial fibrillation (AF) and heart failure (HF). Atrial fibrillation (AF) has been linked to poor prognosis in heart failure (HF) patients with mild to moderate LV dysfunction, and it is most prominent in these patients. Despite advancements in care and treatment options like catheter ablation, managing AF is still a therapeutic challenge even with these advances. Aim/Objective: To determine the frequency of atrial fibrillation in heart failure patients. Subjects and Methods: This cross-sectional study was conducted on 246 patients at Adult Cardiology, NICVD, Karachi for Six months after approval from 31-08-2019 till 29-02-2020. Patients' consent was obtained verbally before data were collected prospectively. There were 246 patients with heart failure who had been diagnosed and met the diagnostic criteria. An overview of the event's history was gathered, as well as demographic data. Qualitative variables were presented as frequency and percentages, while quantitative data were given as simple descriptive statistics such as mean and standard deviation. A p-value of 0.05 or lower is considered statistically significant. Results: A total of 246 patients with heart failure were included in this study. The mean age in our study was 56.78±2.81 years. Whereas, mean BNP and ejection fraction in our study was 1144±87.81 pg./ml and 34.65±4.14 %. 136 (55.3%) were male and 110 (44.7%) were female. Out of 246 patients with heart failure, 52 (21.1%) had atrial fibrillation and 194 (78.9%) did not have atrial fibrillation. Conclusion: The results of this research demonstrated that a large percentage of heart failure patients had atrial fibrillation. Thus, it is essential to focus on a comprehensive way of management of heart failure and its comorbidities rather than primarily treating the cardiac symptoms. Keywords: Heart failure and atrial fibrillation.

THE EFFECT OF SPIRONOLACTONE ON SERUM ELECTROLYTES AND RENAL FUNCTION TESTS IN PATIENTS WITH SEVERE CHRONIC HEART FAILURE

2021 ◽  
Vol 74 (10) ◽  
pp. 2460-2462
Author(s):  
Seher Abdurasool Almedeny ◽  
Jabbar Yasir AL- Mayah ◽  
Mohanmed S. Abdulzahra ◽  
Najah R. Hadi
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Serum Creatinine ◽  
Kidney Function ◽  
Serum Potassium ◽  
Control Group ◽  
Kidney Function Tests ◽  
Serum Electrolytes ◽  
Function Tests ◽  
Renal Function Tests

The aim: To evaluate the effect of single daily 25 mg of spironolactone on serum electrolytes and kidney function tests in patients with severe chronic left sided heart failure. Materials and methods: 60 patients with severe chronic left sided heart failure were enrolled in this study and they were divided in to 2 equal groups’ one group with standard therapy of HF and the other with spironolactone in a dose of 25 mg / day, as an additive therapy to the standard one. Serum electrolytes and kidney function tests were assessed at the beginning of the study and after 3 months. Results: A significant increment in serum potassium (p<0.05) was observed in the spironolactone group after 3 months treatment, while no significant reduction in serum sodium (p>0.05) and no significant increase in serum creatinine and blood urea (p>0.05) was noticed in the same group, control group showed no significant changes (p>0.05), in both serum electrolytes (S.K and S.Na) and renal function tests (S.C and B.U). Conclusions: Spironolactone caused a significant elevation of serum potassium level but this elevation is still with the clinically accepted ranges when low dose of spironolactone is used and with intact renal function. Serum creatinine level was not significantly increased with 25 mgl day of spironolactone. We conclude that Renal function tests namely blood urea and serum Creatinine, and serum potassium should be closely monitored in patients on spironolactone therapy especially those patients who use ACEI and ARBs in addition.

scholarly journals Association Between the Lipid Profile and Renal Dysfunction in the Heart Failure Patients

2019 ◽  
Vol 44 (1) ◽  
pp. 52-61 ◽  
Author(s):  
Hong Zhang ◽  
Shuang Shi ◽  
Xiu-Juan Zhao ◽  
Jun-Kui Wang ◽  
Zhong-Wei Liu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Waist Circumference ◽  
Ejection Fraction ◽  
Lipid Profile ◽  
Renal Dysfunction ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Confounding Factors ◽  
Heart Failure Patients ◽  
Platelet Counts

Background/Aims: In heart failure patients with high prevalence of chronic renal disease (CKD), hospitalization and mortality, whether the lipid profile was associated with renal dysfunction remained unknown. The present study intended to clarify the association between the lipid profile and renal dysfunction in the heart failure patients. Methods: 336 hospitalized heart failure patients with left ventricle ejection fraction (LVEF) ≤45% and New York Heart Association (NYHA) class II-IV were enrolled. The estimated glomerular filtration rate (eGFR) < 90 mL/min·1.73 m2 was defined as renal dysfunction. The demographic, clinical data, blood samples and echocardiography were documented. The Pearson simple linear correlation was performed to evaluate the confounding factors correlated with eGFR. The significantly correlated factors were enrolled in Logistic regression as confounding factors to determine the association between the lipid profile and renal dysfunction in the heart failure patients. Results: 182 patients (54.2%) had renal dysfunction and 154 patients (45.8%) did not have renal dysfunction. The waist circumference, platelet counts, platelet distribution width (PDW), high density lipoprotein-cholesterol (HDL-C), apolipoprotein A1 (apoA1), albumin and left ventricular ejection fraction (LVEF) are positively correlated with eGFR (all P< 0.05). Meanwhile, the age, mean platelet volume (MPV), neutrophilic granulocyte percentage (NEUT%), urea nitrogen (BUN), creatinine and total bilirubin (TBIL) are negatively correlated with eGFR (all P< 0.05). The total cholesterol (TC), triglyceride, low density lipoprotein-cholesterol (LDL-C) and apolipoprotein B (apoB) show no correlation with eGFR. After the adjustment of sex, hypertension, diabetes mellitus, age, waist circumference, platelet counts, MPV, PDW, NEUT%, TBIL, albumin and LVEF, HDL-C is the only lipid factor still significantly associated with renal dysfunction in hospitalized heart failure patients (OR=0.119, P=0.003). Conclusion: Among the lipid profile of TC, triglyceride, LDL-C, HDL-C, apo A1 and apo B, the HDL-C is the only lipid factor significantly associated with renal dysfunction in hospitalized heart failure patients.

scholarly journals Factors Associated with Depression among Heart Failure Patients at Cardiac Follow-Up Clinics in Northwest Ethiopia, 2017: A Cross-Sectional Study

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Kassahun Gebeyehu Yazew ◽  
Debrework Tesgera Beshah ◽  
Mohammed Hassen Salih ◽  
Tadele Amare Zeleke
Keyword(s):  
Heart Failure ◽  
Depressive Symptoms ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
P Value ◽  
Cross Sectional ◽  
Heart Failure Patients ◽  
Referral Hospitals ◽  
Poor Social Support

Background. Depression is a comorbid disorder in patients with heart failure and it is a major public health problem worldwide. Little is known about the depression among heart failure patients in low-income countries, while, in Ethiopia, none was studied. Objective. This study is to assess the prevalence of depression and associated factors among heart failure patients at cardiac follow-up clinics at Amhara Region Referral Hospitals, Northwest Ethiopia, 2017. Methods. A hospital based cross-sectional study was conducted between March 30, 2017, and May 15, 2017, G.C., by using a systematic random sampling technique to select 422 of 1395 HF patients. Structured interviewer-administered questionnaires and patient card review with a checklist that incorporates the PHQ-9 tool for depression measurement were used. The collected data were checked, coded, and entered into Epi-info version 7 and exported to SPSS version 20. Bivariate logistic regression at p-value <0.2 was exported to multivariate logistic regressions and p-value <0.05 was considered statistically significant. Results. A total of 403 were included with a response rate of 95.5%. Among the participants, 51.1% had depressive symptoms. Factors associated with depressive symptoms were poor self-care behavior 1.60 [AOR (95% CI=1.01, 2.55)], poor social support 1.90 [AOR (95% CI=1.16, 3.12)], being female 2.70 [AOR (95% CI=1.44, 5.07)], current smoking history 4.96 [AOR (95% CI=1.54, 15.98)], and duration of heart failure (>1 year) 1.64 [AOR (95% CI=1.04, 2.59)]. Conclusions. Around half of the patients were depressive. The patients who had poor self-care behavior, were females, had poor social support, had a current history of smoking, and had duration of chronic heart failure >1 year need special attention. Therefore, all referral hospitals need efforts to focus on those problems and target improvements of depressive symptoms.

scholarly journals Association Between Characteristics of Hospitalized Heart Failure Patients With Their Needs

2015 ◽  
Vol 8 (6) ◽  
pp. 95 ◽  
Author(s):  
Maria Polikandrioti ◽  
John Goudevenos ◽  
Lampros K. Michalis ◽  
Ioannis G. Koutelekos ◽  
Elpida Georgiadi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Nursing Staff ◽  
Study Data ◽  
Hospitalized Patients ◽  
Public Hospitals ◽  
Professional Status ◽  
Heart Failure Patients ◽  
Patient Groups ◽  
Need For Support ◽  
Artery Disease

<p><strong>INTRODUCTION:</strong> During recent years that life expectancy of heart failure patients has been increased, health professionals put more emphasis on assessing their needs in daily clinical practice. <strong>The aim </strong>of the present study was to explore the association between characteristics of hospitalized heart failure patients with their needs.</p><p><strong>METHODS: </strong>A sample of 190 hospitalized patients with HF, recruited from public hospitals in Greece, was enrolled in the study. Data were collected by the completion of a questionnaire which included socio-demographic and clinical characteristics and the questionnaire "Needs of hospitalized patients with coronary artery disease" which is consisted of 6 subscales. Statistical methods used were Kruskal wallis-test or Mann-Whitney test and Spearmans' rho coefficient. Multiple regression analysis was performed in order to evaluate the association between patients’ characteristics and the significance of their needs.</p><p><strong>RESULTS: </strong>124 (65.3%) of hospitalized heart failure participants were men and 89 (46.8%) of participants were more than 70 years old. 145 (76.3%) had prior experience of hospitalization due to heart failure. The need for support and guidance was statistically significantly associated with the degree of information, (p=&lt;0.001). The need for information from the medical and nursing staff was significantly associated with marital status and degree of information (p=0.001 and p&lt;0.001 respectively). The need for need for being in contact with other patient groups, and ensuring communication with relatives<strong> </strong>was statistically significantly associated with the professional status and degree of information, (p=0.037 and p=&lt;0.001 respectively). The need for individualized treatment and the need for patient’s personal participation to his/her treatment as well as the<strong> </strong>need to meet the emotional and physical needs were statistically significant associated with the degree of information, (p=&lt;0.001, p=&lt;0.001 respectively). Lastly, the need to trust the medical and nursing staff was statistically significantly associated with the place of residence and the degree of information, (p=0.023 and p&lt;0.001). These results were confirmed by the multiple linear regression after controlling for potential confounders.</p><p><strong>CONCLUSIONS: </strong>Information seems to be of vital importance when assessing the needs of heart failure patients. Therefore, providing elaborate information should be an integral part of their therapeutic regimen.</p>

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