scholarly journals Parental, Gestational, and Early-life Exposure to Indoor Environmental Hazardous Facto Rs on Allergic Rhinitis Among Preschool Children in Urumqi City: A Case-control Study

2021 ◽  
Author(s):  
Haonan Shi ◽  
Huizhen Qi ◽  
Lan Jiang ◽  
Yuting Lin ◽  
Tingting Wang ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Preschool Children ◽  
Case Control ◽  
Related Factors ◽  
Parental History ◽  
Environmental Correlates ◽  
Early Life Exposure ◽  
History Of ◽  
Impaired Quality

Abstract BackgroundAllergic rhinitis is a disease associated with impaired quality of life and heredity. This study aimed to investigate the association of allergic rhinitis (AR) in preschool children with exposure to indoor environment-related factors early in life. MethodsIn August 2019, we implemented a study among 2020 preschool children in Urumqi City using a case-control design. The study included parental reports for the occurrence of AR in children, parental history of respiratory disease, and indoor environmental correlates of maternal exposure from 1 year prior to pregnancy until the child's age of 0-1 years.ResultsMode of birth (caesarean section) (OR=1.31, 95%CI=1.02~1.67), father with AR (OR=2.67, 95%CI=2.08~3.44), mother with AR (OR=3.70, 95%CI=2.88~4.74), mother with asthma (OR=3.11, 95%CI=1.18~8.20), and mother with newly purchased furniture in the parents' residence during pregnancy (OR=1.49, 95%CI=1.03~2.14) were risk factors for AR in children. ConclusionsThe focus of allergic rhinitis should should be on children with a family history of AR and asthma and caesarean delivery. Primary prevention efforts for AR in preschool children are avoiding exposure of children to indoor environmental hazardous factors early in life.

scholarly journals Early childhood traffic-related air pollution and risk of allergic rhinitis at 2–4 years of age modification by family stress and male gender: a case-control study in Shenyang, China

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Shuai Hao ◽  
Fang Yuan ◽  
Pai Pang ◽  
Bo Yang ◽  
Xuejun Jiang ◽  
...  
Keyword(s):  
Air Pollution ◽  
Allergic Rhinitis ◽  
Preschool Children ◽  
Case Control Study ◽  
Family Stress ◽  
Case Control ◽  
Male Gender ◽  
Exposure Level ◽  
Early Exposure ◽  
Control Study

Abstract Background Few studies have explored the modifications by family stress and male gender in the relationship between early exposure to traffic-related air pollution (TRAP) and allergic rhinitis (AR) risk in preschool children. Methods We conducted a case-control study of 388 children aged 2–4 years in Shenyang, China. These children AR were diagnosed by clinicians. By using measured concentrations from monitoring stations, we estimated the exposures of particulate matter less than 10 μm in diameter (PM10), nitrogen dioxide (NO2), ozone (O3), carbon monoxide (CO), and sulfur dioxide (SO2) in preschool children aged 2–4 years. After adjusted potential confounding factors, we used logistic regression model to evaluate the odds ratio (OR) and 95% confidence interval (CI) for childhood AR with exposure to different air pollutants according to the increasing of the interquartile range (IQR) in the exposure level. Results The prevalence of AR in children aged 2–4 years (6.4%) was related to early TRAP exposure. With an IQR (20 μg/m3) increase in PM10 levels, an adjusted OR was significantly elevated by 1.70 (95% CI, 1.19 to 2.66). Also, with an IQR (18 μg/m3) increase in NO2, an elevated adjusted OR was 1.85 (95% CI, 1.52 to 3.18). Among children with family stress and boys, PM10 and NO2 were positively related to AR symptoms. No significant association was found among children without family stress and girls. Conclusions Family stress and male gender may increase the risk of AR in preschool children with early exposure to PM10 and NO2.

scholarly journals Risk factors associated with peripheral neuropathy among diabetic individuals: a case control study

2021 ◽  
Vol 8 (2) ◽  
pp. 768
Author(s):  
Christa Kingston ◽  
Aravindan J. ◽  
Srikumar Walsalam
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Diabetic Neuropathy ◽  
Case Control Study ◽  
Case Control ◽  
Diabetic Patients ◽  
Factors Associated ◽  
History Of ◽  
Control Study

Background: Diabetic neuropathy is one among the most common complication in diabetes mellitus. Diabetic peripheral neuropathy hinders the quality of life causing morbidity and mortality. The purpose of this study was to find the risk factors associated with diabetic neuropathy.Methods: This case control study involved 100 diabetic patients attending the Dohnavur fellowship hospital, Dohnavur from October 2019 to March 2020. Sociodemographic profile and diabetic characteristics of the study group were obtained and analysed. Diagnosis of Diabetic Neuropathy was done by using the diagnostic method proposed by American Diabetic Association.Results: Of the total study population with mean age 59.43 years, 63% had family history of diabetes. Almost 70% had poor diabetic control. Statistically significant relationships were found between neuropathy and duration of diabetes, glycaemic control, history of hypertension, monofilament test and pinprick sensation.Conclusions: In this study, glycemic control, dyslipidemia and hypertension were modifiable risk factors for diabetic neuropathy. Early interventional programs to sensitize diabetics on these factors could improve the quality of life of Diabetic patients. 

scholarly journals Influence of obesity, parental history of diabetes, and genes in type 2 diabetes: A case-control study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jaime Berumen ◽  
Lorena Orozco ◽  
Miguel Betancourt-Cravioto ◽  
Héctor Gallardo ◽  
Mirella Zulueta ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Case Control Study ◽  
Case Control ◽  
Parental History ◽  
History Of ◽  
Parental History Of Diabetes ◽  
Control Study

scholarly journals The AAA Risk Factors Scale: A New Model to Screen for the Risk of Asthma, Allergic Rhinitis and Atopic Dermatitis in Children

2018 ◽  
Vol 27 (5) ◽  
pp. 472-480 ◽  
Author(s):  
Souheil Hallit ◽  
Chantal Raherison ◽  
Diana Malaeb ◽  
Rabih Hallit ◽  
Nelly Kheir ◽  
...  
Keyword(s):  
Risk Factors ◽  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Allergic Disease ◽  
Disease Risk ◽  
Allergic Diseases ◽  
Parental History ◽  
Respiratory Problems ◽  
History Of ◽  
Or History

Objective: To create an allergic disease risk factors scale score that would screen for the risk assessment of asthma, allergic rhinitis and atopic dermatitis (AD) in children from 3 to 17 years. Methods: This case-control study, conducted between December 2015 and April 2016, enrolled 1,274 children. The allergic disease risk factors scale was created by combining environmental, exposure to toxics during pregnancy and breastfeeding and parental history of allergic diseases. Results: Playing on carpets, male gender, child’s respiratory problems or history of eczema before the  age of 2 years, and humidity significantly increased the odds of allergies in the child. Maternal waterpipe smoking, maternal history of rhinitis, history of asthma in the mother or the father, along with the maternal drug intake or alcohol consumption during pregnancy significantly increased the odds of allergies in the child. There was a significant increase in allergy diseases per category of the allergic disease risk factors scale (p < 0.001 for trend). Scores ≤2.60 best represented control individuals, while scores > 5.31 best represented children with allergic diseases. Conclusion: Allergic diseases seem to be linked to several risk factors in our population of school children. Many environmental factors might be incriminated in these allergic diseases.

scholarly journals Early life exposure to traffic-related air pollution and allergic rhinitis in preschool children

2016 ◽  
Vol 121 ◽  
pp. 67-73 ◽  
Author(s):  
Qihong Deng ◽  
Chan Lu ◽  
Yichen Yu ◽  
Yuguo Li ◽  
Jan Sundell ◽  
...  
Keyword(s):  
Air Pollution ◽  
Allergic Rhinitis ◽  
Preschool Children ◽  
Early Life ◽  
Early Life Exposure

Oral Health–Related Quality of Life in Children in Chile Treated for Cleft Lip and Palate: A Case-Control Approach

2017 ◽  
Vol 54 (2) ◽  
pp. 15-20 ◽  
Author(s):  
Pedro C. Aravena ◽  
Tania Gonzalez ◽  
Tamara Oyarzún ◽  
César Coronado
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Cleft Lip ◽  
Case Control ◽  
Control Group ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
History Of

Objective To compare the oral health–related quality of life of patients treated for cleft lip and/or cleft palate (CL/P) versus unaffected children between 8 and 15 years of age using a Spanish-language version of the Child Oral Health Impact Profile (COHIP-Sp) administered to a Chilean population. Design A cross-sectional study with a matched case-control design was used. Methods Participants were 48 children (mean age 11.3 years) with a history of CL/P from three cities in Chile and one group of 96 children (mean age 11.2 years) unaffected by CL/P. The COHIP-Sp was applied to both groups. Quality of life was compared according to the overall score and the average score of items and domains on the COHIP-Sp scale between the two groups (Mann-Whitney U test; P < .05). Results The COHIP-Sp score was 94.1 ± 19.3 in children with CL/P and 97.1 ± 15.6 for the control group ( P = .31). A significantly lower score was observed in the group with CL/P in the domains “functional well-being” ( P = .001) and “school environment” ( P = .001); the only average in favor of the quality of life in children with CL/P was in “self-image” ( P = .0002). Conclusion The oral health–related quality of life of children with a history of CL/P was similar to that of the control group. Nevertheless, a lower quality of life was observed concerning items associated with speech and being understood by other people. Further study into the risk factors associated with surgery and rehabilitative treatment is recommended.

scholarly journals The Burden of Depressive and Bipolar Disorders in Celiac Disease

2015 ◽  
Vol 11 (1) ◽  
pp. 180-185 ◽  
Author(s):  
Mauro Giovanni Carta ◽  
Alessandra Conti ◽  
Federica Lecca ◽  
Federica Sancassiani ◽  
Giulia Cossu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Celiac Disease ◽  
Affective Disorders ◽  
Bipolar Disorders ◽  
Structured Interview ◽  
Preventive Action ◽  
History Of ◽  
Impaired Quality ◽  
Control Study

Introduction: Aims: to measure the association between Celiac Disease (CD) and affective disorders, particularly Bipolar Disorder (BD), since it has not been studied yet, and to measure how much the quality of life (QoL) of a person with CD is affected by comorbidity with these disorders. Methods: Design: Case-control study. Cases: 60 consecutive patients with CD. Controls: 240 subjects without CD, randomly selected after sex- and age-matching from a database of an epidemiological study. Psychiatric diagnoses according to DSM-IV carried out by physicians using structured interview tools (ANTAS-SCID). QoL was measured by means of SF-12. Results: The lifetime prevalence of Major Depressive Disorder (MDD) was higher in CD than in controls (30.0% vs 8.3%, P<0.0001) as well as Panic Disorder (PD) (18.3% vs 5.4%, P<0.001) and BD (4.3% vs 0.4%, P<0.005). Patients with CD show a lower mean score than controls on SF12 (35.8±5.7 vs. 38.2±6.4; p=0.010), but those without comorbidity with MDD, PD and BD do not. The attributable burden of CD in worsening QoL - when comorbid with these disorders - was found comparable to that of serious chronic diseases like Wilson’s Disease, and lower than Multiple Sclerosis only. Conclusion: MDD, PD and BD are strictly associated with CD. The comorbidity with these disorders is the key determinant of impaired quality of life in CD. Thus a preventive action on mood and anxiety disorders in patients suffering from CD is required. Moreover a screening for CD in people with affective disorders and showing key symptoms or family history of CD is recommended.

SP1.1.6Incidence of post colonoscopy colorectal cancer, are we compliant with national guidelines?

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Eyas Mohamed ◽  
Bhairavi Srikumar ◽  
Bronwyn Shishkin ◽  
Nikhil Kulkarni
Keyword(s):  
Colorectal Cancer ◽  
Diverticular Disease ◽  
Bowel Preparation ◽  
Colonic Polyps ◽  
Prior History ◽  
National Guidelines ◽  
Related Factors ◽  
Patient Demographics ◽  
History Of

Abstract Aims To investigate the incidence of post colonoscopy colorectal cancer (PCCRC) at a district NHS trust and assess compliance with UK key performance indicators and quality assurance standards for colonoscopy guidelines endorsed by JAG and the ACPGBI Methods We conducted a retrospective review of our trust colorectal MDT database to identify patients diagnosed with colorectal cancer in the period between January 2016 till June 2019 who underwent a colonoscopy within 6-36 month prior to their diagnosis with colorectal cancer. Patient demographics, indication of colonoscopy, date of cancer diagnosis, procedure related factors such as quality of bowel preparation, presence of diverticular disease, prior history of inflammatory bowel disease, previously diagnosed polyps and also grade of endoscopist were extrapolated. Results 1323 patients were diagnosed with colorectal cancer during the study period, out of these there were 111 patients who underwent a colonoscopy within 6-36 month prior to their diagnostic colonoscopy. After exclusion of cases with anastomotic recurrence (n = 2) and cases with no PCCRC (n = 82), there were 27 patients with confirmed PCCRC in accordance with WEO classification (PCCRC 2.8%, acceptable target 5%) Upon review of the 27 cases with PCCRC, there was equal gender distribution while the majority were 71-80 years old. There was evidence of diverticular disease in 44% and previous colonic polyps in 48%. The quality of bowel preparation was recorded as good in 25 cases while grade of endoscopist was consultant (n = 24), associate specialist (n = 1), nurse endoscopist (n = 2) Conclusions The incidence of PCCRC in our trust falls within national guidelines.

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