scholarly journals Clinicopathological Progress of Colorectal Resection in Gynecological Malignancy Patients : Does the risk of anastomotic leakage increase after surgery?

2021 ◽  
Author(s):  
Ayoung Kang ◽  
Byung-Soo Park ◽  
Sung Hwan Cho ◽  
Gyung Mo Son ◽  
Yong Jung Song ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Anastomotic Leakage ◽  
Medical Records ◽  
Colorectal Resection ◽  
Gynecological Cancer ◽  
Benign Diseases ◽  
Gynecological Malignancy ◽  
The Mean ◽  
Preoperative Albumin ◽  
Female Genital

Abstract Objective: This study was conducted to investigate the clinicopathological outcomes of colorectal resection in patients with advanced gynecological malignancies.Methods: We reviewed the medical records of 104 patients of gynecological cancer with co-operation for colorectal resection from December 2008 to August 2020 by retrospective cohort study in a single center (PNUYH). Variables for risk factors and postoperative complications were compared by descriptive statistics. We excluded the cases with malignancies from other than female genital organs, gynecological benign diseases, primary creation of stoma, and any other bowel surgeries except colorectal resection.Results: Of 104 patients in total, the mean age was 62.0 years. The most common gynecological malignancy was ovarian cancer(85 patients, 81.7%) and the most commonly performed operation was low anterior resection(80 patients, 76.9%). 61 patients(58.7%) had postoperative complications, while only 3 patients(2.9%) with anastomotic leakage. Only preoperative albumin was statistically significant(p=0.019) among the risk factors.Conclusion: Our experience suggests that colorectal resection can be safely and efficaciously performed in patients with advanced gynecological malignancy.

scholarly journals Keystone-design perforator island flaps for the management of complicated epidermoid cysts on the back

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Chi Sun Yoon ◽  
Hyo Bong Kim ◽  
Young Keun Kim ◽  
Hoon Kim ◽  
Kyu Nam Kim
Keyword(s):  
Postoperative Complications ◽  
Medical Records ◽  
Summary Score ◽  
Assessment Scale ◽  
Complete Excision ◽  
Epidermoid Cysts ◽  
Scar Assessment ◽  
Tension Change ◽  
The Mean ◽  
Surgical Modality

Abstract Complicated epidermoid cysts (ECs) occur commonly on the back, but few reports have described their management. We present our experience in managing patients with ECs on the back using a keystone-design perforator island flap (KDPIF) reconstruction, thereby focusing on reduction and redistribution of wound tension. Altogether, 15 patients (average age, 48.067 ± 14.868 years) underwent KDPIF reconstructions after complete excision of complicated ECs on the back. We retrospectively reviewed the medical records and clinical photographs of all patients. Final scar appearance was evaluated using the Patient and Observer Scar Assessment Scale (POSAS). All patients had ruptured ECs, while 6 patients also had cellulitis of the surrounding tissues. All defects, after complete excision of ECs and debridement of surrounding unhealthy tissues, were successfully covered with KDPIF. The mean ‘tension-change’ at the defect and donor sites was −4.73 ± 0.21 N and −4.88 ± 0.25 N, respectively (p < 0.001). The mean ‘rate of tension-change’ at the defect and donor sites was −69.48 ± 1.7% and −71.16 ± 1.33%, respectively (p < 0.001). All flaps survived with no postoperative complications. The mean observer scar assessment scale (OSAS) summary score and patient scar assessment scale (PSAS) total score were 14.467 ± 5.069 and 15.6 ± 6.512, respectively. Overall, we suggest that KDPIF reconstruction is a good surgical modality for the management of complicated ECs on the back.

Rapid rituximab infusion is safe and well tolerated in malignant and benign disease

2020 ◽  
pp. 107815522097845
Author(s):  
Sorana G Ursu ◽  
Derek L Rinchuse ◽  
John Lister
Keyword(s):  
Medical Records ◽  
Malignant Disease ◽  
Benign Disease ◽  
P Value ◽  
Infusion Time ◽  
Benign Diseases ◽  
Secondary Objective ◽  
The Mean ◽  
The One ◽  
Related Reaction

Introduction Although the safety and feasibility of rapid rituximab administration has been demonstrated for B-cell malignancies, there is scant data in the literature to support its use in patients with benign diseases. Objective To identify the incidence of infusion-related reaction with rapid rituximab administration in malignant and benign disease. Secondary objective was to determine the infusion time saved between standard administration and rapid rituximab administration. Methods A retrospective cohort study was conducted by reviewing electronic medical records from December 2018 to April 2020. Adult patients who received at least one dose of rapid rituximab were included. Results A total of 63 patents were included. The incidence of an infusion-related reaction with rapid rituximab was 1.6%. The one patient who reacted had a diagnosis of neuromyelitis optica. The mean infusion time saved was 2.9 hours (95% CI: 2.7-3.1; P-value <0.001). Conclusion The use of the rapid rituximab administration is safe and well tolerated in both benign and malignant disease.

Keystone-Designed Perforator Island Flaps for the Coverage of Traumatic Pretibial Defects in Patients With Comorbidities

2017 ◽  
Vol 16 (4) ◽  
pp. 302-309 ◽  
Author(s):  
Chi Sun Yoon ◽  
Sang Il Kim ◽  
Hoon Kim ◽  
Kyu Nam Kim
Keyword(s):  
Soft Tissue ◽  
Postoperative Complications ◽  
Medical Records ◽  
Operative Time ◽  
Free Flaps ◽  
Defect Size ◽  
Soft Tissue Defects ◽  
Algorithmic Approach ◽  
The Mean ◽  
Tissue Defects

Reconstruction of pretibial skin and soft-tissue defects remains a challenge because this area has less underlying tissues and limited tissue mobility. Here, we present a retrospective review of our experience with pretibial reconstruction using the keystone-designed perforator island flap (KDPIF) in patients with comorbidities. All defects resulted from nononcological causes. We describe the expanding versatility of KDPIF reconstruction for pretibial defects and suggest a simple algorithmic approach. The medical records of 9 patients who underwent reconstruction with a KDPIF to cover a pretibial defect between May 2016 and June 2017 were reviewed. Clinical and operative data were collected. All 9 KDPIFs fully survived. The defect size varied from 3 × 2 cm2 to 8 × 6 cm2. The flap size varied from 5 × 3 to 20 × 10 cm2. The mean operative time was 90.4 minutes (range = 37-127 minutes). No postoperative complications occurred. The cosmetic results were favorable, and all patients were satisfied with the final outcomes. Thus, the KDPIF is a good reconstruction modality with few complications and provides an alternative to free flaps for pretibial defect reconstruction in patients with comorbidities.

scholarly journals External validation of anastomotic leakage risk analysis system in patients who underwent colorectal resection

2019 ◽  
Author(s):  
SADETTİN ER ◽  
SABRİ ÖZDEN ◽  
FARUK KOCA ◽  
BARIŞ DOĞU YILDIZ ◽  
BÜLENT CAVİT YÜKSEL ◽  
...  
Keyword(s):  
Anastomotic Leakage ◽  
Colorectal Resection ◽  
External Validation ◽  
Operative Management ◽  
Colon Resection ◽  
Study Patient ◽  
Prediction System ◽  
System Data ◽  
The Mean ◽  
Analysis System

Background and Aim: One of the most feared complication after colon resection for carcinoma is anastomotic leakage. Prediction of anastomotic leakage can alter pre- and per-operative management of patients. This study validates an anastomotic leakage prediction system. Materials and Methods: Ninety-five patients who underwent colonic resection between January 1, 2016 and January 30, 2017 were included in the study. Patient records and electronic charting system data were used to calculate anastomotic leakage risk on the http://www.anastomoticleak.com/ website. Results: Fifty-six (58.9%) patients were male and thirty-nine (41.1%) were female. The mean age was 61.7 (min:33, max:90). Six (6.3%) patients had anastomotic leakage. According to the ROC analysis, the area under curve for the prediction system was 0.767. Conclusion: The prediction system for anastomotic leakage produced significant results for our patient population. It can be effectively utilized in preoperative and perioperative measures to prevent anastomotic leakage. Keywords: Anastomotic leakages; Validation Studies; Colorectal Carcinoma

scholarly journals Relationship between the Preoperative Albumin Levels and Postoperative Complications in Carcinoma Stomach Patients

2021 ◽  
pp. 24-28
Author(s):  
Marella Haneesh ◽  
Samuel Dev Merlin
Keyword(s):  
Postoperative Complications ◽  
Haemoglobin Level ◽  
Albumin Level ◽  
Preoperative Period ◽  
Duration Of Stay ◽  
Medical College ◽  
The Mean ◽  
Carcinoma Stomach ◽  
The Relationship ◽  
Preoperative Albumin

Background: Malnutrition in gastrointestinal cancer patients adversely affects the surgical outcomes. low serum albumin and postoperative complications were associated with one another. Objectives: To find out the relationship between preoperative albumin levels and postoperative complications among carcinoma stomach patients. Materials and Methods: The present study was a single institution retrospective study carried out in the department of general surgery, Saveetha medical college and hospital between February 2021 to July 2021. Fifty patients diagnosed with carcinoma stomach and electively posted for surgery during the study period were included into the study. The data was collected using structured proforma. Preoperative albumin and haemoglobin levels were estimated using blood samples. All the data collected were analysed using SPSS version 23. Results: The preoperative albumin levels among those who had reported complication was 3.04±0.19 g/dl while those who had no complication in the postoperative period had preoperative albumin level of 3.82±0.31g/dl. The preoperative mean haemoglobin level among those who developed complications in the post operative period was 9.68±0.95 mg/dl and the mean haemoglobin level among those with no complication was 11.46±1.89 mg/dl. Albumin and haemoglobin values were found to be negatively correlated with duration of stay in hospital. Conclusion: Malnutrition in the preoperative period would increase the probability of occurrence of postoperative complications and increased duration of stay in hospital. Attending to malnutrition of the admitted patients in the preoperative period would help in decreasing the postoperative complications and duration of stay.

Evaluation of Low-Dose Gentamicin Once Daily Dosing Regimen at A General Hospital in Malaysia

2018 ◽  
Vol 9 (01) ◽  
Author(s):  
Ab Rahman A F ◽  
Md Sahak N. ◽  
Ali A. M.
Keyword(s):  
Medical Records ◽  
Public Hospital ◽  
Low Dose ◽  
Dosing Regimen ◽  
Once Daily ◽  
Neutropenic Sepsis ◽  
Wide Acceptance ◽  
The Mean ◽  
Initiation Of Therapy ◽  
Almost All

Objective: Once daily dosing (ODD) aminoglycoside is gaining wide acceptance as an alternative way of dosing. In our setting it is the regimen of choice whenever gentamicin is indicated. The objective of this study was to evaluate the practice of gentamicin ODD in a public hospital in Malaysia. Methods: We conducted a retrospective review of medical records of patients on gentamicin ODD who were admitted to Hospital Melaka during January 2002 until March 2010. All adult patients who were on ODD gentamicin with various level of renal function were included in the study. Patients on gentamicin less than 72 hours and pregnant women were excluded. Results: From 110 patients, 75 (68.2%) were male and 35 (31.8%) were female. Indications for ODD gentamicin included pneumonia, 34 (31.0%) neutropenic sepsis, 27 (24.5%) and sepsis, 11 (10.0%). The mean dose and duration of gentamicin was 3.2 mg/kg/day and 7 days, respectively. Almost all patients were on gentamicin combined with other antibiotics. Clinical cure based on fever resolution was found in 89.1% of patients treated with ODD. Resolution of fever took an average of 48 hours after initiation of therapy. The evaluation for bacteriologic cure could not be performed because of insufficient data on culture and sensitivity. Out of 38 patients with analyzable serum creatinine data, four patients might have developed nephrotoxicity. Conclusion: In our setting, lower dosages of ODD gentamicin when used in combination with other antibiotics seemed to be effective and safe in treating most gram negative infections.

Rice tablet (Aluminum Phosphide) poisoning

2016 ◽  
Vol 5 (11) ◽  
pp. 5041
Author(s):  
Farkhondeh Jamshidi ◽  
Ahmad Ghorbani ◽  
Sina Darvishi*
Keyword(s):  
Medical Records ◽  
Statistical Tests ◽  
Patient Records ◽  
Demographic Information ◽  
Aluminum Phosphide ◽  
Men And Women ◽  
Significant Difference ◽  
The Mean ◽  
Aluminum Phosphide Poisoning ◽  
Commit Suicide

The abuse of some pesticides especially to suicide is one of the current problems of pesticides. Aluminum phosphide induced poisoning usually happens to suicide and sometimes it is due to accidental occupational exposure and in a few cases it has some criminal intensions. This study is conducted to evaluate patients poisoned with aluminum phosphide. In the present study the medical records of cases of poisoning with rice tablets (aluminum phosphide) hospitalized in Ahvaz Razi hospital is studied. Accordingly, a checklist is prepared that included demographic information of patients (age, gender) and information on patient records (information on poisoning) are completed using the patients’ medical records. The analysis of data is done by SPSS V22. 18 patients poisoned with rice tablet (aluminum phosphide) are studied. Results of the study show that 11 patients are male and seven are female. The mean patient age is 27.06 ±8.04 years that is 28 ±9 and 25 ±6.02 in men and women respectively. Statistical tests show no statistically significant difference in mean age in both genders (P> 0.05). Among patients, 11 subjects took aluminum phosphide to attempt suicide and 3 cases took it unintentionally and of course the reason is not mentioned in four cases. Among the patients who tried to commit suicide by taking aluminum phosphide, 6 cases are male and 5 cases are female that no statistically significant difference is observed between the genders in this respect (P> 0.05). In addition to the study of the complications caused by this poisoning and its mortality, it is recommended to responsible authorities to provide the necessary educations and treatments to prevent this type of poisoning.

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