Mobile Health Apps Related to Emergency Drugs: Systematic Search on App Stores and Content Analysis (Preprint)

2021 ◽  
Author(s):  
Sebastián García-Sánchez ◽  
Beatriz Somoza-Fernández ◽  
Ana de Lorenzo-Pinto ◽  
Cristina Ortega-Navarro ◽  
Ana Herranz-Alonso ◽  
...  
Keyword(s):  
Medication Reconciliation ◽  
Dose Adjustment ◽  
Adverse Reactions ◽  
Healthcare Professionals ◽  
Drug Information ◽  
Pregnancy And Lactation ◽  
Emergency Drugs ◽  
User Ratings ◽  
Usual Dosage ◽  
In Pregnancy

BACKGROUND Drug referencing mobile apps are among the most frequently apps used by emergency health professionals. Currently there are no studies about the quantity and quality of apps related to emergency drugs. OBJECTIVE The aim of this study was to identify apps designed to assist emergency healthcare professionals in managing drugs and to analyze their contents. METHODS We performed an observational, cross-sectional, descriptive study of apps about emergency drugs. A search was conducted in February 2021 on the iOS and Android platforms. Apps identified were downloaded and their main characteristics were evaluated by 2 independent researchers. Developer affiliation, cost, updates, user ratings and number of downloads were analyzed. We also evaluated the number of drugs described, the inclusion of bibliographic references and the presence of the following drug information: commercial presentations, usual dosage, dose adjustment for renal failure, mechanism of action, therapeutic indications, contraindications, interaction with other medicinal products, use in pregnancy and lactation, adverse reactions, method of preparation and administration, stability data/incompatibilities, identification of high-alert medications, positioning in treatment algorithms, information about medication reconciliation and cost. RESULTS We identified a total of 49 apps. Of these, 32 (65.3%) were found at both digital platforms, 11 (22.4%) were only available for Android and 6 (12.2%) for iOS. A total of 20 (40.8%) required payment (ranging from 0.59€ to 179.99€) and 11 (22.4%) were developed by non-healthcare professionals. The weighted user rating mean was 4.023 out of 5 (SD 0.71). Overall, 22 apps (44.9%) were focused on emergency drugs and 27 (55.1%) on emergency medicine. More than a half (61.7%) did not include bibliographic references or had not been updated for more than a year (59.2%). The median number of drugs was 66 (range 4 to 5000+). Most apps included information about usual dosage (87.8%) and therapeutic indications (79.2%), while information about contraindications (55.3%) and adverse reactions (51.1%) was only found in about half of apps. Dose adjustment for renal failure (31.9%), interactions (21.3%) and use in pregnancy and lactation (31.9%) were described in less than a half of apps. Furthermore, only 3 (6.4%) identified high-alert medications and 1 (2.1%) included information about medication reconciliation. Health-related developer, main topic of the app (emergency drugs or emergency medicine) and greater amount of drug information were not statistically associated with higher user ratings (P=.99, P=.09 and P=.31, respectively). CONCLUSIONS We provide a comprehensive review of apps related to emergency drugs. Our findings show that information on authorship, drug characteristics and bibliographic references is frequently scarce, so we propose some recommendations to take into account when developing an app of these characteristics. Future efforts should be done to increase regulation of drug referencing apps and to carry out a more frequent and documented review of their clinical content.

Drag Use in Pregnancy and Lactation: the Work of a Regional Drug Information Center

1995 ◽  
Vol 29 (6) ◽  
pp. 632-633 ◽  
Author(s):  
Antonio Addis ◽  
Piero Impicciatore ◽  
Daniela Miglio ◽  
Fabio Colombo ◽  
Maurizio Bonati ◽  
...  
Keyword(s):  
Drug Information ◽  
Information Center ◽  
Pregnancy And Lactation ◽  
In Pregnancy

The Influence of the Food and Drug Administration Pregnancy and Lactation Labeling Rule on Drug Information Resources

2020 ◽  
pp. 106002802095665
Author(s):  
John Brock Harris ◽  
Amy P. Holmes ◽  
Lea S. Eiland
Keyword(s):  
Drug Administration ◽  
Health Care Providers ◽  
Drug Information ◽  
Food And Drug Administration ◽  
The United States ◽  
Primary Objective ◽  
Information Resources ◽  
Care Providers ◽  
Pregnancy And Lactation ◽  
In Pregnancy

Background Drug information resources are commonly used by health-care providers answering pregnancy-related medication questions. In 2015, the United States Food and Drug Administration approved a new pregnancy and lactation medication labeling content and format, removing the pregnancy category, and using a narrative. Despite labeling requirements changing, it is unknown if drug information resources updated monographs to reflect these changes. Objective The primary objective was to evaluate if commonly used drug information resources provide pregnancy information listed similar to the requirements of the Pregnancy and Lactation Labeling Rule (PLLR). Secondary analyses included evaluating the references and inclusion of the pregnancy category rating. Methods Pregnancy recommendations for 23 medications were evaluated in 9 drug information resources (Clinical Pharmacology, Drugs in Pregnancy and Lactation, Epocrates®, First Databank, LexiComp® Online, LexiComp® Online Pregnancy & Lactation, In-Depth, Medi-Span®, Micromedex®, and Multum®). The number of references per drug monograph and most recent reference publication year was obtained. Results LexiComp® Online Pregnancy & Lactation, In-Depth mimics the new PLLR structure and consistently had the highest number of and most recent references when the medication was included. Drugs in Pregnancy and Lactation was the next most similar in content with the PLLR and second in most references per monograph; however, the most recent reference was the textbook publication year. Conclusion and Relevance LexiComp® Online Pregnancy & Lactation, In-Depth and Drugs in Pregnancy and Lactation provided pregnancy information in a format most similar to the PLLR. However, several drug information resources contained pregnancy categories ratings that were to be removed from medication labeling per the PLLR.

THIOURACIL TREATMENT IN PREGNANCY AND LACTATION IN THE DOG

1962 ◽  
Vol 40 (3) ◽  
pp. 430-440 ◽  
Author(s):  
K. E. Arosenius ◽  
H. Derblom ◽  
G. Nylander
Keyword(s):  
Thyroid Gland ◽  
List Type ◽  
Histological Changes ◽  
Morphological Effect ◽  
Iodine Metabolism ◽  
Pregnancy And Lactation ◽  
In Pregnancy

ABSTRACT The offspring of bitches treated with thiouracil during pregnancy and lactation were studied with regard to certain aspects of iodine metabolism and also to the morphological effect on the thyroid gland, as compared with controls of the same age and weight. At the age of six months, when the dogs were virtually fully grown, the thyroid gland still exhibited the effects of the thiouracil treatment of the mothers as manifested by an increased uptake of 131I, enlargement, and histological changes of a hyperplastic type. The significance of these deviations from normal iodine metabolism and morphology is discussed with particular reference to the dangers of thiouracil medication during pregnancy.

A systematic review of the use of prazosin in pregnancy and lactation

2021 ◽  
Author(s):  
Ashley D. Davidson ◽  
Amritha Bhat ◽  
Frances Chu ◽  
Jessie N. Rice ◽  
N. Aba Nduom ◽  
...  
Keyword(s):  
Systematic Review ◽  
Pregnancy And Lactation ◽  
In Pregnancy

scholarly journals Consent in pregnancy - an observational study of ante-natal care in the context of Montgomery: all about risk?

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jacqueline A. Nicholls ◽  
Anna L. David ◽  
Joseph Iskaros ◽  
Dimitrios Siassakos ◽  
Anne Lanceley
Keyword(s):  
Qualitative Research ◽  
Observational Study ◽  
Pregnant Women ◽  
Social Factors ◽  
Healthcare Professionals ◽  
Effective Interaction ◽  
Clinical Decision ◽  
Place Of Birth ◽  
Clinical Risk ◽  
In Pregnancy

Abstract Background How to best support pregnant women in making truly autonomous decisions which accord with current consent law is poorly understood and problematic for them and their healthcare professionals. This observational study examined a range of ante-natal consultations where consent for an intervention took place to determine key themes during the encounter. Methods Qualitative research in a large urban teaching hospital in London. Sixteen consultations between pregnant women and their healthcare professionals (nine obstetricians and three midwives) where ante-natal interventions were discussed and consent was documented were directly observed. Data were collectively analysed to identify key themes characterising the consent process. Results Four themes were identified: 1) Clinical framing - by framing the consultation in terms of the clinical decision to be made HCPs miss the opportunity to assess what really matters to a pregnant woman. For many women the opportunity to feel that their previous experiences had been ‘heard’ was an important but sometimes neglected prelude to the ensuing consultation; 2) Clinical risk dominated narrative - all consultations were dominated by information related to risk; discussion of reasonable alternatives was not always observed and women’s understanding of information was seldom verified making compliance with current law questionable; 3) Parallel narrative - woman-centred experience – for pregnant women social factors such as the place of birth and partner influences were as or more important than considerations of clinical risk yet were often missed by HCPs; 4) Cross cutting narrative - genuine dialogue - we observed variably effective interaction between the clinical (2) and patient (3) narratives influenced by trust and empathy and explicit empowering language by HCPs. Conclusion We found that ante-natal consultations that include consent for interventions are dominated by clinical framing and risk, and explore the woman-centred narrative less well. Current UK law requires consent consultations to include explicit effort to gauge a woman’s preferences and values, yet consultations seem to fail to achieve such understanding. At the very least, consultations may be improved by the addition of opening questions along the lines of ‘what matters to you most?’

scholarly journals The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation

2020 ◽  
Vol 37 (3) ◽  
pp. 306-312 ◽  
Author(s):  
Alicja Góralczyk ◽  
Katarzyna Kolossa ◽  
Marzena Waszczak-Jeka ◽  
Rafał Adamczak ◽  
Sławomir Jeka
Keyword(s):  
Disease Modifying Antirheumatic Drugs ◽  
Antirheumatic Drugs ◽  
Pregnancy And Lactation ◽  
Disease Modifying ◽  
In Pregnancy

The influence of intake of dietary energy in pregnancy and lactation upon sow productivity

1968 ◽  
Vol 71 (2) ◽  
pp. 215-222 ◽  
Author(s):  
F. W. H. Elsley ◽  
R. M. MacPherson ◽  
I. McDonald
Keyword(s):  
Daily Intake ◽  
Dietary Energy ◽  
Large White ◽  
Treatment Groups ◽  
Daily Energy ◽  
Reproductive Life ◽  
Pregnancy And Lactation ◽  
Daily Intakes ◽  
Practical Implications ◽  
In Pregnancy

SUMMARYFifty-two Large White gilts, arranged in thirteen groups of four litter sisters, were allocated at mating to one of four treatment groups. These treatments, arranged as a 2 × 2 factorial, allowed daily energy intakes in pregnancy of 8·3 Meal (H(e)) or 5·2 Meal (L(e)) and of average daily intake during lactation of 20 Meal (h(e)) or 13·8 Meal (m(e)). Daily intakes of protein, minerals and vitamins were similar for all treatments. There were no consistent differences in health or breeding regularity between the treatments.The H(e) sows had a net gain in pregnancy 22 kg greater than the L(e) sows. Feeding the higher level in lactation (h(e) resulted in a reduced sow weight loss during lactation of 20, 12 and 10 kg in the first, second and third parities respectively, as compared with the m(e) sows. There were no consistent effects on the numbers of pigs born apart from the first litter in which L(e) sows produced significantly larger litters at birth. The higher energy intakes in pregnancy and lactation led to very similar increases in the weights of the piglets, of the order of 0.1 kg at birth, 0.4 kg at 3 weeks of age, and 1.1 kg at 8 weeks of age. Sowsgiven the same overall energy intake throughout their reproductive life (H(e) m(e), L(e) h(e)) at the end of the third litter had similar live weights and had produced a similar total weight of weaned pigs. The practical implications of these results are discussed.

Sign in / Sign up

Export Citation Format

Share Document