scholarly journals Chlamydia trachomatis and urogenital mycoplasms in nonconococcal urethirits in men

2010 ◽  
Vol 63 (1-2) ◽  
pp. 47-50
Author(s):  
Sonja Vesic ◽  
Jelica Vukicevic ◽  
Eleonora Gvozdenovic ◽  
Dusan Skiljevic ◽  
Slobodanka Janosevic ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Sexually Active ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Nongonococcal Urethritis ◽  
Etiological Agents ◽  
The One

Introduction. Nongonococcal urethritis is the most common sexually transmitted infection in men, with vast majority of the etiological agents such as Chlamydia trachomatis, followed by urogenital mycoplasmas. The aim of this study was to determine the prevalence of Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis in nongonococcal urethritis in men, and to examine infections associated with these agents. Material and methods. 299 sexually active, heterosexual men with nongonococcal urethritis were included into the study. Urethral samples were taken with a dacron swab placed into the urethra up to 2-3 cm. The Direct immunojluorescence tehnique was performed for identification of Chlamydia trachomatis. Ureaplasma urealyticum and Mycoplasma hominis were detected with Mycoplasma 1ST assay. Results. Chlamydia trachomatis was detected in 22.75%, Uraeplasma urealyticum in 21.08% and Mycoplasma hominis in 8.02% cases. We found no significant differences in prevalence between Chlamydia trachomatis and Ureaplasma urealyticym (p>0.05). Monoinjections were found in 51.85% with significantly higher rate (p<0.01) than associated infections (11.70%). Among associated infections, coinfection of Chlamydia trahomatis and Ureaplasma urealyticum was predominant. Association of Chlamydia trachomatis with urogenital mycoplasmas was significantly higher (p<0.05) than the one between Ureaplasma urealyticum and Mycoplasma hominis. In 36.45% patients no patogenic microorganisms were detected. Conclusion. These results confirmed the etiological role of Chlamydia trachomatis and urogenital mycoplasmas in nongonococcal urethritis with prevalence of 51.85% in monoinfections and 11.70% in associated infections. In 36.45% of cases the etiology of urethritis was not elucidated. These results suggest that more sensitive diagnostic tool should be applied when searching for the detailed etiology of nongonococcal urethritis.

Bacteriology of the urethra in normal men and men with nongonococcal urethritis

1977 ◽  
Vol 6 (5) ◽  
pp. 482-488
Author(s):  
W R Bowie ◽  
H M Pollock ◽  
P S Forsyth ◽  
J F Floyd ◽  
E R Alexander ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Ureaplasma Urealyticum ◽  
Previous History ◽  
Mycoplasma Hominis ◽  
Sexually Active ◽  
History Of ◽  
Nongonococcal Urethritis ◽  
Normal Men ◽  
Aerobic And Anaerobic ◽  
Microbiological Flora

Sixty-nine Caucasian males without a previous history of urethritis and who developed nongonococcal urethritis (NGU) and 39 similar men without urethritis (NU) were cultured from the urethra for Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, aerobes, and anaerobes. C. trachomatis infection was proven by culture of serology in 26 (38%) of the NGU group and 1 (3%) of the NU group; the C. trachomatis-negative NGU group had significantly more U. urealyticum (81%) than the C. trachomatis-positive NGU group (42%) or the NU group (59%). Aerobes were isolated from significantly more NU men (91%) than from men with NGU (66%). The aerobic and anaerobic flora of the two NGU groups were similar. The NU group had significantly more aerobic lactobacilli. Haemophilus vaginalis, alpha-hemolytic streptococci (not Streptococcus faecalis), and anaerobes, predominantly Bacteroides species. This study has provided information about the prevalence and the variety of the aerobic and anaerobic microbiological flora of the anterior urethra of sexually active males. It does not implicate any bacteria other than C. trachomatis and U. urealyticum as potential causes of NGU.

scholarly journals Frequency and antibiotic resistance of Ureaplasma urealyticum and Mycoplasma hominis in genital samples of sexually active individuals

2011 ◽  
Vol 152 (42) ◽  
pp. 1698-1702 ◽  
Author(s):  
Balázs Farkas ◽  
Eszter Ostorházi ◽  
Katinka Pónyai ◽  
Béla Tóth ◽  
Elmardi Adlan ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Sexually Transmitted Diseases ◽  
Ureaplasma Urealyticum ◽  
Antibiotic Sensitivity ◽  
Mycoplasma Hominis ◽  
High Rate ◽  
Sexually Active ◽  
Sexually Transmitted ◽  
Causative Agents ◽  
Resistant Strains

Ureaplasma urealyticum and Mycoplasma hominis have important role among the causative agents of sexually transmitted diseases. Aim: The aim of the study was to determine the frequency and antibiotic resistance of Ureaplasma urealyticum and Mycoplasma hominis in genital samples obtained from patients examined in the Sexually Transmitted Diseases Centre of the Department of Dermatology, Venerology and Dermatooncology, Semmelweis University, Budapest between May 1, 2008 and July 31, 2010. Patients and methods: Samples were taken from the urethra in men and from the cervix and urethra in women by universal swab (Biolab®) into Urea-Myco DUO kit (Bio-Rad®) and were incubated for 48 hours at 37 C°. Antibiotic sensitivity of positive samples was determined in U9 bouillon using SIR Mycoplasma kit (Bio-Rad®). Results: Samples for 4154 patients aged 16-60 years were examined. In 247/4154 samples (6%) U. urealyticum and in 26/4154 samples (0.63%) M. hominis was isolated from the genital tract. Most U. urealyticum and M. hominis strains (75% and 77%, respectively) were cultured from cervix, while the remaining 25%, and 23% from the male and female urethra, respectively. U. urealyticum and M. hominis were most commonly detected in patients aged between 21 and 40 years. The majority of U. urealyticum strains were sensitive to tetracycline (94%), doxycycline (95%), azithromycin (88%) and josamycin (90%), but were resistant to ofloxacin (21%), erythromycin (85%) and clindamycin (79%). Seventy-seven percent of the U. urealyticum strains were simultaneously resistant to erythromycin and clindamycin, suggesting that ex iuvantibus therapies may select cross-resistant strains to both antibiotics. The resistance of M. hominis to clindamycin, doxycycline, ofloxacin and tetracycline varied between 4% and 12 %. Conclusions: Because none of the strains was sensitive to all examined antibiotics, the antibiotic sensitivity of U. urealyticum and M. hominis strains should be determined. The high rate of ofloxacin, erythromycin and clindamycin resistance should be considered in the therapy of U. urealyticum infections in Hungary. This is the firstsuch a clinical microbiological study in this topic in Hungary. Orv. Hetil., 2011, 152, 1698–1702.

scholarly journals Molecular epidemiology of non-viral sexually transmitted infections in the central Alpine province of Bolzano, northern Italy from April 2016 to March 2017

2018 ◽  
Vol 33 (1) ◽  
Author(s):  
Richard Aschbacher ◽  
Francesca Romagnoli ◽  
Elisa Masi ◽  
Valentina Pasquetto ◽  
Franco Perino ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Trichomonas Vaginalis ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Mycoplasma Genitalium ◽  
Northern Italy ◽  
Sexually Transmitted ◽  
Ureaplasma Parvum ◽  
One Year ◽  
The One

Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Ureaplasma parvum, Ureaplasma urealyticum, Mycoplasma hominis and Mycoplasma genitalium are established or presumed as (??) STI pathogens. The present study aims  at ng describing the one-year molecular epidemiology of these seven pathogens in the Province of Bolzano, Northern Italy. From April 2016 to March 2017, a total of  2,949 patients, mainly females, were enrolled and 3,427 urine, vaginal, endocervical and/or urethral samples were subjected to simultaneous analysis of the seven pathogens by means of Real Time Polymerase Chain Reaction (AnyplexTM II STI-7 Detection Kit Seegene, Seoul, Korea). At least one of the seven microorganisms was detected in 40.7% of patients, with an uneven distribution: 43.1% in females (F) and 29.8% (p<0.001) in males (M). The prevalence of microorganisms was as follows: 30.3% U. parvum (F: 35.6%, M: 8.3%), 6.9% U. urealyticum (F: 6.8%, M: 7.0%), 4.9% M. hominis (F: 5.4%, M: 2.3%), 4.9% C. trachomatis (F: 3.4%, M: 11.4%), 1.1% M. genitalium (F: 1.0%, M: 1.2%), 1.2% N. gonorrhoeae (F: 0.17%, M: 5.6%) and 0.40% T. vaginalis (F: 0.38%, M: 0.53%). Mixed infections were detected in 7.4% of patients. The highest prevalence was observed for U. parvum, followed by U. urealyticum and M. hominis and a significant  presence of multi-pathogen infections was registered.

Mycoplasma and Chlamydia in Adenoids and Tonsils of Children Undergoing Adenoidectomy or Tonsillectomy

1994 ◽  
Vol 103 (2) ◽  
pp. 135-138 ◽  
Author(s):  
David Huminer ◽  
Rudi Levy ◽  
Silvio Pitlik ◽  
Zmira Samra
Keyword(s):  
Chlamydia Trachomatis ◽  
Chlamydial Infection ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Pathogenetic Role ◽  
Mycoplasma Spp ◽  
Genital Mycoplasmas

The prevalence of mycoplasmal and chlamydial infection was assessed in 83 children undergoing adenoidectomy, tonsillectomy, or both procedures for recurrent adenotonsillitis or obstructive symptoms. Throat smears (surface specimens) and minced adenoids and tonsils (core specimens) were cultured for Mycoplasma spp and for Chlamydia spp. Isolation rates in adenoidal specimens were as follows: Mycoplasma hominis, surface 7.1%, core 2.9%; and Ureaplasma urealyticum, surface 1.4%, core 2.9%. Mycoplasma hominis was also found in tonsillar specimens: surface 14.3%, core 20%. Chlamydia trachomatis was isolated only from a single core adenoidal specimen. The rate of mycoplasma isolation was significantly higher in children with recurrent adenotonsillitis (34.5%) than in those with obstructive symptoms (3.7%). Our findings document colonization of genital mycoplasmas in adenoids and tonsils of children with recurrent adenotonsillitis. Further studies are needed to evaluate the possible pathogenetic role of these microorganisms in adenotonsillar infection.

scholarly journals INCIDENCE OF SEXUALLY TRANSMITTED INFECTIONS: LOCAL STUDY IN UKRAINE

World Science ◽  
2018 ◽  
Vol 2 (8(36)) ◽  
pp. 4-7
Author(s):  
Fedorych P. V. ◽  
Mavrov G. I.
Keyword(s):  
Human Papillomavirus ◽  
Chlamydia Trachomatis ◽  
Sexually Transmitted Infections ◽  
Trichomonas Vaginalis ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Mycoplasma Genitalium ◽  
Local Study ◽  
Sexually Transmitted ◽  
Clinically Significant

Introduction.The structure of incidence of sexually transmitted infections is changing constantly. Information on such changes supports correct planning of clinical and diagnostic activities of institutions providing specialized medical care by qualified specialists.Objective:to investigate the prevalence of sexually transmitted infections with pathogens clinically significant to the genitourinary system in Ukraine and at the local level.Materials and methods. Polymerase chain reaction was used to test the biological material obtained from the genitourinary clinical specimens from subjects with sexually transmitted infections, who underwent clinical and laboratory examinations in Oleksandrivsk Clinical Hospital (Kyiv, Ukraine) for Chlamydia trachomatis, Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum, Trichomonas vaginalis, Human papillomavirus, and Neisseria gonorrhoea. During 2017, 607 subjects of both genders, including 295 (48.6%) females and 312 (51.4%) males, were examined. Their mean age was 32±3.5.Findings. Chlamydia trachomatis was found in 159 (26.2%) of 607 examined subjects – 85 males and 74 females. Mycoplasma hominis was found in 122 of 585 (21.1%) examined subjects – 64 males and 58 females. Mycoplasma genitalium, respectively, in 17 (6.62%) of 258 subjects – 6 males and 11 females. Ureaplasma urealyticum was found in the largest number of subjects (305, i.e. in 48.77% of 601 examined subjects) – 157 males and 148 females. Trichomonas vaginalis was found in 28 (5.23%) of 535 subjects – 15 males and 13 females. Human papillomavirus was found in 158 of 297 (53.2%) examined subjects – 88 males and 70 females. Neisseria gonorrhea was found in 33 of 297 (8.45%) subjects – 8 males and 25 females.Conclusions. As suggested by the local study of the sexually transmitted infections incidence in Ukraine, the most clinically significant for the genitourinary system are Human papillomavirus (53.2%), Ureaplasma urealyticum (48.77%), Chlamydia trachomatis (26.2%) and Mycoplasma hominis (21.1%). Therefore, tests for these pathogens in the specified region is currently the most appropriate during diagnostic examinations and counselling of subjects with genitourinary infections.

scholarly journals Prevalence Rates of Chlamydia Trachomatis and Other Sexually Transmitted Organisms in Infertile Couples Attending a Tertiary Medical Centre in Malaysia

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Umi Kalsom A ◽  
Suvra B ◽  
Zainul RMR ◽  
Siti Norlia O ◽  
Zalina I ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Trichomonas Vaginalis ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Mycoplasma Genitalium ◽  
Married Couples ◽  
Prevalence Rates ◽  
Sexually Transmitted ◽  
Neisseria Gonorrhoea ◽  
Infertile Couples

 INTRODUCTION: Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV) and Mycoplasma genitalium (MG) infections are well recognized and prevalent sexually transmitted infections (STIs). The role of Mycoplasma spp and Ureaplasma spp are still controversial as some are commensals of genitourinary tract. OBJECTIVES: To estimate the prevalence rate of 7 organisms: Chlamydia trachomatis, Neisseria gonorrhoea, Mycoplasma genitalium, Trichomonas vaginalis, Mycoplasma hominis, Ureaplasma urealyticum (UU) and Ureaplasma parvum (UP) in infertile married couples during infertility evaluation. MATERIALS & METHODS: A total of 274 samples from all of the 137 couples who attended the reproductive center from June to December 2014 were collected. Detection of the organisms was performed using multiplex polymerase chain reaction. RESULTS: STI-associated organisms were detected in 35.4% (97/274) of subjects. The prevalence rates of CT, MG, TV, UU, MH were 7.3%,1.1%, 0.4%,5.4% and 5.1% respectively. Twenty-one (7.7%) subjects were positive for more than one organism. 24/274 (8.8%) of subjects had history of urogenital tract-related symptoms and 50% (12/24) were tested positive to one or more organisms. The presence of symptoms in both male and female subjects were found to be 10% (2/20) in CT infection, 10% (7/67) in UP, 14% (2/14) in MH and 13% (2/15) in UU infections. CONCLUSION: Sexually transmitted organisms were detected in one third of subjects planning for fertility evaluation. The absence of symptom in most subjects particularly in CT infection emphasizes the need for microbiological screening during infertility evaluation. The presence of genital ureaplasmas and mycoplasmas in infertile couples should not be neglected. There is a growing need to clarify whether their roles are simply colonizers or pathogens implicated in infertility.

scholarly journals Relevant prevalence of Mycoplasma hominis and Ureaplasma urealyticum serogroups in HIV-1 infected men without urethritis symptoms

2000 ◽  
Vol 42 (4) ◽  
pp. 185-188 ◽  
Author(s):  
Caio Mauricio Mendes CORDOVA ◽  
Regina A. F. CUNHA
Keyword(s):  
Opportunistic Infections ◽  
Clinical Symptoms ◽  
Ureaplasma Urealyticum ◽  
Mycoplasma Hominis ◽  
Mycoplasma Species ◽  
Immunosuppressed Patients ◽  
Severe Infections ◽  
Male Patients ◽  
The One

M. hominis and U. urealyticum are the better-known mycoplasma species pathogenic to the human genitourinary tract, causing mainly urethritis, bacterial vaginosis and pregnancy complications. In HIV-infected patients, the prevalence and role of these species is still not well known. The aim of this work was to determinate the prevalence of these species in this group of male patients (HIV group), in comparison to a group of men with clinical symptoms of urethritis (STD group). M. hominis was isolated from 7.5% patients (8/106) and U. urealyticum from 18.9% patients (20/106) from the HIV group, being among these 62.5% and 85% in significant concentrations, respectively. In the STD group these rates were 0.9% (1/110) for M. hominis and 13.6% (15/110) for U. urealyticum, being 100% and 93.3% in significant concentrations, respectively. We could demonstrate infection rates by these mycoplasma species in the HIV group as high as the one found in the STD one, what may indicate the occurrence of opportunistic infections in our population. This fact is discussed here because in immunosuppressed patients, specially M. hominis has been reported causing severe infections, even systemically.

scholarly journals Profil uretritis gonokokus dan non-gonokokus di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari – Desember 2012

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Alson . Sambonu ◽  
Nurdjannah J. Niode ◽  
Herry E.J. Pandeleke
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Sexual Partner ◽  
Ureaplasma Urealyticum ◽  
Burning Sensation ◽  
Purulent Discharge ◽  
Gonococcal Infection ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Gonococcal Urethritis

Abstract: Gonococcal urethritis (GU) is a sexually transmitted infection (STI) which is caused by Neisseria Gonorrhoeae bacteria. In GU, there is an urethral inflammation caused by negative Gram diplococcus ( its natural reservoir is human) and the symptoms are purulent discharge from external urethral orificium, burning sensation during urination, distal urethra itching, dysuria, vaginal or penile discharge, and erection pain. Non-Gonococcal Urethritis (NGU) is an urethral inflammation that is not caused by Gonococcal infection, but due to Chlamydia trachomatis and Ureaplasma urealyticum. The symptoms are penile discharge, burning sensation and pain during urination, and itching. This study aimed to obtain the profiles of gonococcal and non-gonococcal urethritis in Dermatovenereology Clinic of Prof. Dr. R. D. Kandou General Hospital Manado from January to December 2012. This was a retrospective descriptive study based on GU and NGU types, symptoms, sexual partner, occupation, and farmacological therapy. The results showed that of 74 STI cases there were 11 GU cases (14.9%) and 4 UNG cases (5.4%). Most of GU and NGU patients were 25-44 years (n = 10, 66.7%), with dysuria (n = 11, 73.3%), prostitute as sexual partner (n = 10, 66.7%), working as entrepreneur (n = 12, 80%), and farmacological therapy for GU is cefixime (n = 9, 81.8%) and for NGU is doxycyclin (n = 3, 75%). Keywords: gonococcal urethritis, non-gonococcal urethritis Abstrak: Uretritis gonore (UG) merupakan suatu penyakit infeksi menular seksual (IMS) yang disebabkan oleh kuman Neisseria gonorrhoeae. Pada UG terjadi peradangan uretra oleh diplokokus Gram negatif yang reservoir alaminya ialah manusia dan ditandai adanya pus yang keluar dari orifisium uretra eksternum, rasa panas, gatal di bagian distal uretra, disuria, polakisuria, keluar duh tubuh dari ujung uretra yang kadang-kadang disertai darah dalam urin, dan disertai rasa nyeri saat ereksi. Uretritis non Gonore (UNG) adalah suatu peradangan pada uretra yang bukan disebabkan oleh infeksi gonokokus seperti Chlamydia trachomatis dan Ureaplasma urealyticum dengan gejala seperti discharge dari penis, rasa terbakar atau sakit saat buang air kecil dan gatal. Penelitian ini bertujuan untuk mengetahui profil uretritis gonokokus dan non gonokokus di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari-Desember 2012. Jenis penelitian ini deskriptif retrospektif berdasarkan jenis penyakit UG dan UNG, umur, keluhan, pasangan seksual, pekerjaan, dan terapi farmakologis. Hasil penelitian menunjukkan dari 74 kasus IMS terdapat 11 kasus UG (14,9%) dan 4 kasus UNG (5,4%). Penderita UG dan UNG terbanyak pada kelompok umur 25-44 tahun (n = 10, 66,7%), dengan keluhan disuria (n = 11, 73,3%), pasangan seksual dengan WPS (n = 10, 66,7%), pekerjaan wiraswata (n = 12, 80%), serta terapi farmakalogis pada UG ialah cefixime (n = 9, 81,8%) dan pada UNG ialah doxycyclin (n = 3, 75%).Kata kunci: uretritis gonokokus, uretritis non gonokokus

scholarly journals Potential for Phages in the Treatment of Bacterial Sexually Transmitted Infections

Antibiotics ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1030
Author(s):  
Kathryn Cater ◽  
Ryszard Międzybrodzki ◽  
Vera Morozova ◽  
Sławomir Letkiewicz ◽  
Marzanna Łusiak-Szelachowska ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Sexually Transmitted Infections ◽  
Phage Therapy ◽  
Ureaplasma Urealyticum ◽  
Shigella Flexneri ◽  
Treponema Pallidum ◽  
Bacteriophage Therapy ◽  
Transmitted Infection ◽  
Sexually Transmitted

Bacterial sexually transmitted infections (BSTIs) are becoming increasingly significant with the approach of a post-antibiotic era. While treatment options dwindle, the transmission of many notable BSTIs, including Neisseria gonorrhoeae, Chlamydia trachomatis, and Treponema pallidum, continues to increase. Bacteriophage therapy has been utilized in Poland, Russia and Georgia in the treatment of bacterial illnesses, but not in the treatment of bacterial sexually transmitted infections. With the ever-increasing likelihood of antibiotic resistance prevailing and the continuous transmission of BSTIs, alternative treatments must be explored. This paper discusses the potentiality and practicality of phage therapy to treat BSTIs, including Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum, Streptococcus agalactiae, Haemophilus ducreyi, Calymmatobacterium granulomatis, Mycoplasma genitalium, Ureaplasma parvum, Ureaplasma urealyticum, Shigella flexneri and Shigella sonnei. The challenges associated with the potential for phage in treatments vary for each bacterial sexually transmitted infection. Phage availability, bacterial structure and bacterial growth may impact the potential success of future phage treatments. Additional research is needed before BSTIs can be successfully clinically treated with phage therapy or phage-derived enzymes.

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