scholarly journals Towards a New Generation of Cognitive Diagnosis

Author(s):  
Qi Liu

Cognitive diagnosis is a type of assessment for automatically measuring individuals' proficiency profiles from their observed behaviors, e.g. quantifying the mastery level of examinees on specific knowledge concepts/skills. As one of the fundamental research tasks in domains like intelligent education, a number of Cognitive Diagnosis Models (CDMs) have been developed in the past decades. Though these solutions are usually well designed based on psychometric theories, they still suffer from the limited ability of the handcrafted diagnosis functions, especially when dealing with heterogeneous data. In this paper, I will share my personal understanding of cognitive diagnosis and review our recent developments of CDMs mostly from a machine learning perspective. Meanwhile, I will show the wide applications of cognitive diagnosis.

Author(s):  
S.J. Krause ◽  
W.W. Adams

Over the past decade low voltage scanning electron microscopy (LVSEM) of polymers has evolved from an interesting curiosity to a powerful analytical technique. This development has been driven by improved instrumentation and in particular, reliable field emission gun (FEG) SEMs. The usefulness of LVSEM has also grown because of an improved theoretical and experimental understanding of sample-beam interactions and by advances in sample preparation and operating techniques. This paper will review progress in polymer LVSEM and present recent results and developments in the field.In the early 1980s a new generation of SEMs produced beam currents that were sufficient to allow imaging at low voltages from 5keV to 0.5 keV. Thus, for the first time, it became possible to routinely image uncoated polymers at voltages below their negative charging threshold, the "second crossover", E2 (Fig. 1). LVSEM also improved contrast and reduced beam damage in sputter metal coated polymers. Unfortunately, resolution was limited to a few tenths of a micron due to the low brightness and chromatic aberration of thermal electron emission sources.


Author(s):  
John L. Hutchison

Over the past five years or so the development of a new generation of high resolution electron microscopes operating routinely in the 300-400 kilovolt range has produced a dramatic increase in resolution, to around 1.6 Å for “structure resolution” and approaching 1.2 Å for information limits. With a large number of such instruments now in operation it is timely to assess their impact in the various areas of materials science where they are now being used. Are they falling short of the early expectations? Generally, the manufacturers’ claims regarding resolution are being met, but one unexpected factor which has emerged is the extreme sensitivity of these instruments to both floor-borne and acoustic vibrations. Successful measures to counteract these disturbances may require the use of special anti-vibration blocks, or even simple oil-filled dampers together with springs, with heavy curtaining around the microscope room to reduce noise levels. In assessing performance levels, optical diffraction analysis is becoming the accepted method, with rotational averaging useful for obtaining a good measure of information limits. It is worth noting here that microscope alignment becomes very critical for the highest resolution.In attempting an appraisal of the contributions of intermediate voltage HREMs to materials science we will outline a few of the areas where they are most widely used. These include semiconductors, oxides, and small metal particles, in addition to metals and minerals.


Methodology ◽  
2014 ◽  
Vol 10 (3) ◽  
pp. 100-107 ◽  
Author(s):  
Jürgen Groß ◽  
Ann Cathrice George

When a psychometric test has been completed by a number of examinees, an afterward analysis of required skills or attributes may improve the extraction of diagnostic information. Relying upon the retrospectively specified item-by-attribute matrix, such an investigation may be carried out by classifying examinees into latent classes, consisting of subsets of required attributes. Specifically, various cognitive diagnosis models may be applied to serve this purpose. In this article it is shown that the permission of all possible attribute combinations as latent classes can have an undesired effect in the classification process, and it is demonstrated how an appropriate elimination of specific classes may improve the classification results. As an easy example, the popular deterministic input, noisy “and” gate (DINA) model is applied to Tatsuoka’s famous fraction subtraction data, and results are compared to current discussions in the literature.


1988 ◽  
Vol 27 (1) ◽  
pp. 81-83
Author(s):  
Nadeem A. Burney

Its been long recognized that various economies of the world are interlinked through international trade. The experience of the past several years, however, has demonstrated that this economic interdependence is far greater than was previously realized. In this context, the importance of international economic theory as an area distinct from general economics hardly needs any mentioning. What gives international economic theory this distinction is international markets for some goods and effects of national sovereignty on the character of economic activity. Wilfred Ethier's book, which incorporates recent developments in the field, is an excellent addition to textbooks on international economics for one- or twosemester undergraduate courses. The book mostly covers standard topics. A distinguishing feature of this book is its detailed analysis of the flexible exchange rates and a discussion of the various approaches used for their determination. Within each chapter, the author has extensively used facts, figures and major events to clarify the concepts in the light of the theoretical framework. The book also discusses, in a fair amount of detail, the existing international monetary system and the role of various international organizations.


2020 ◽  
Author(s):  
Lungwani Muungo

The purpose of this review is to evaluate progress inmolecular epidemiology over the past 24 years in canceretiology and prevention to draw lessons for futureresearch incorporating the new generation of biomarkers.Molecular epidemiology was introduced inthe study of cancer in the early 1980s, with theexpectation that it would help overcome some majorlimitations of epidemiology and facilitate cancerprevention. The expectation was that biomarkerswould improve exposure assessment, document earlychanges preceding disease, and identify subgroupsin the population with greater susceptibility to cancer,thereby increasing the ability of epidemiologic studiesto identify causes and elucidate mechanisms incarcinogenesis. The first generation of biomarkers hasindeed contributed to our understanding of riskandsusceptibility related largely to genotoxic carcinogens.Consequently, interventions and policy changes havebeen mounted to reduce riskfrom several importantenvironmental carcinogens. Several new and promisingbiomarkers are now becoming available for epidemiologicstudies, thanks to the development of highthroughputtechnologies and theoretical advances inbiology. These include toxicogenomics, alterations ingene methylation and gene expression, proteomics, andmetabonomics, which allow large-scale studies, includingdiscovery-oriented as well as hypothesis-testinginvestigations. However, most of these newer biomarkershave not been adequately validated, and theirrole in the causal paradigm is not clear. There is a needfor their systematic validation using principles andcriteria established over the past several decades inmolecular cancer epidemiology.


2019 ◽  
pp. 451-458
Author(s):  
Peter W. Rein

Developments in the technology of production of sugar from sugarcane tend to be incremental improvements in an effort to reduce costs and boost revenue. Nonetheless the developments are significant and contribute to sustainable sugarcane enterprises. Some technologies have adapted to changing environmental conditions, and more attention is being given to boosting revenue through associated activities, particularly in enhancing the potential for sugarcane operations to exploit the energy value of sugarcane. This paper outlines recent developments of interest in processing sugarcane.


2017 ◽  
Vol 40 (3) ◽  
pp. 295-310
Author(s):  
Sabine Wilke

Every late spring since 1951, the Wiener Festwochen bring performers from around the world to Vienna for an opportunity to share recent developments in performance styles and present them to a Viennese public that seems to be increasingly open to experimentation. These festival weeks solidify a specific form of Viennese self-understanding and self-representation as a culture that is rooted in performance. This essay seeks to link two recent Austrian performances—one of them was part of the Wiener Festwochen in 2016, the other was staged in downtown Linz during the past few years—to this Austrian and specifically Viennese culture of performance by reading them as contemporary articulations of a tradition of radical performance art that can be traced back to the Viennese Actionism of the sixties and later feminist articulations in the seventies and eighties. They play on the dramatic effect of these actions, specifically their joy in cruelty, chaos, and orgiastic intoxication, by staging regressions and thus making visible what has been dammed up and repressed in contemporary society.1 Just as their historical models, these two performances merge the performing and the fine arts and they highlight provocative, controversial, and, at times, violent content. But they do it in an interspecies context that adds an entire layer of complexity to the project of societal and cultural critique.


Author(s):  
Ieva Rodiņa

The aim of the research “Historical Memory in the Works of the New Generation of Latvian Theater Artists: The Example of “The Flea Market of the Souls” is to focus on the current but at the same time little discussed topic in Latvian theater – the change of generations and the social processes connected to it, that are expressed on the level of world views, experiences, intergenerational relationships. Most directly, these changes are reflected in the phenomenon of historical memory. The concept of “postmemory” was defined by German professor Marianne Hirsch in 1992, suggesting that future generations are closely related to the personal and collective cultural traumas of previous generations, which are passing on the past experience through historical memory, thus affecting the present. Grotesque, self-irony, and focusing on socio-political, provocative questions and themes are the connecting point of the generation of young Latvian playwrights born in the late 1980s and early 1990s, including such personalities as Jānis Balodis, Rasa Bugavičute-Pēce, Matīss Gricmanis, Justīne Kļava, etc. However, unlike Matīss Gricmanis or Janis Balodis who represent the aesthetics of political theater, in Justīne Kļava’s works, sociopolitical processes become the background of a generally humanistic study of the relationships between generations. This theme is represented not only in “The Flea Market of the Souls”, but also in other plays, like “Jubilee ‘98” and “Club “Paradise””. The tendency to investigate the traces left by the Soviet heritage allows to define these works as autobiographical researches of the identity of the post-Soviet generation, analyzing life in today's Latvia in terms of historical memory. Using the semiotic, hermeneutic, phenomenological approach, the play “The Flea Market of the Souls” and its production in Dirty Deal Teatro (2017) are analyzed as one of the most vivid works reflecting the phenomenon of historical memory in recent Latvian original drama.


2019 ◽  
Vol 26 (13) ◽  
pp. 2330-2355 ◽  
Author(s):  
Anutthaman Parthasarathy ◽  
Sasikala K. Anandamma ◽  
Karunakaran A. Kalesh

Peptide therapeutics has made tremendous progress in the past decade. Many of the inherent weaknesses of peptides which hampered their development as therapeutics are now more or less effectively tackled with recent scientific and technological advancements in integrated drug discovery settings. These include recent developments in synthetic organic chemistry, high-throughput recombinant production strategies, highresolution analytical methods, high-throughput screening options, ingenious drug delivery strategies and novel formulation preparations. Here, we will briefly describe the key methodologies and strategies used in the therapeutic peptide development processes with selected examples of the most recent developments in the field. The aim of this review is to highlight the viable options a medicinal chemist may consider in order to improve a specific pharmacological property of interest in a peptide lead entity and thereby rationally assess the therapeutic potential this class of molecules possesses while they are traditionally (and incorrectly) considered ‘undruggable’.


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