scholarly journals Incidental Meckel’s diverticula low grade neuroendocrine tumor coexisting with synchronous sigmoidian and perianal adenocarcinoma

2021 ◽  
Vol 26 (6) ◽  
pp. 3110-3113
Author(s):  
SORIN PAUN ◽  
IOAN TANASE ◽  
BOGDAN STOICA ◽  
CEZAR CIUBOTARU ◽  
DIANA PAUN
Keyword(s):  
Primary Tumor ◽  
Intestinal Tract ◽  
Tumor Development ◽  
High Variability ◽  
Second Primary ◽  
Low Grade ◽  
A Site ◽  
Gastro Intestinal Tract ◽  
Tumor Bearer ◽  
Common Malignancy

Although rarely, due to the high variability of the possible tissues encountered in it’s wall, the Meckel’s diverticula can represent a site for tumor development in 0,5-3,2% cases. Data in the literature shows that the most common malignancy at this level is represented by neuroendocrine tumors (NET) the observed incidence of neurendocrine tumors and other primary neoplasia, varies between 12-55%. Moreover, the gastro-intestinal tract was the second primary tumor bearer encountered.

Selenium excretion in sheep

1986 ◽  
Vol 37 (2) ◽  
pp. 201 ◽  
Author(s):  
JP Langlands ◽  
JE Bowles ◽  
GE Donald ◽  
AJ Smith
Keyword(s):  
Organic Matter ◽  
Small Intestine ◽  
Nutrient Intake ◽  
Intestinal Tract ◽  
High Variability ◽  
Faecal Excretion ◽  
Factors Affecting ◽  
Gastro Intestinal Tract ◽  
Microbial Action ◽  
Se Status

Factors affecting the fate of selenium (Se) in the gastro-intestinal tract and its excretion in faeces were examined in four experiments. Large quantities of Se were secreted into the anterior region of the small intestine and were absorbed from the posterior region. These processes were not affected by the infusion of arsenite or by tying off the pancreatic duct. Faecal and urinary Se excretion were increased in sheep of higher Se status; the increase in faecal excretion was evident for several weeks after a change in Se intake but was not significant because of high variability between animals; it was attributed to the release of Se when tissues were turned over as tissue Se concentration equilibrated with contemporary Se intake. The bile was a possible route for the entry of such Se into the gastro-intestinal tract, and relationships between biliary Se and whole blood and plasma Se concentrations are presented. Faecal Se excretion was more sensitive to an increase in the organic matter intake than to an increase in forage Se concentration in one experiment. It is postulated that Se excretion was increased because rumen microbial activity was stimulated by the increased nutrient intake, and this increased the quantity of dietary Se which was reduced to an unavailable form by rumen microbial action.

Non Steroidal Anti-Inflammatory Drug Induced Damage on Lower Gastro-Intestinal Tract: Is There an Involvement of Microbiota?

2014 ◽  
Vol 9 (3) ◽  
pp. 196-204 ◽  
Author(s):  
Lucia Montenegro ◽  
Giuseppe Losurdo ◽  
Raffaele Licinio ◽  
Maria Zamparella ◽  
Floriana Giorgio ◽  
...  
Keyword(s):  
Intestinal Tract ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Gastro Intestinal Tract

scholarly journals Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma

2021 ◽  
Vol 22 (5) ◽  
pp. 2602
Author(s):  
Emilie Viennois ◽  
Benoit Chassaing
Keyword(s):  
Intestinal Inflammation ◽  
Tumor Development ◽  
Low Grade ◽  
Gastrointestinal Cancers ◽  
Cancer Initiation ◽  
And Function ◽  
The Impact ◽  
Chronic Intestinal Inflammation ◽  
Low Grade Inflammation ◽  
Intestinal Adenoma

Inflammation is a well-characterized critical driver of gastrointestinal cancers. Previous findings have shown that intestinal low-grade inflammation can be promoted by the consumption of select dietary emulsifiers, ubiquitous component of processed foods which alter the composition and function of the gut microbiota. Using a model of colitis-associated cancer, we previously reported that consumption of the dietary emulsifiers carboxymethylcellulose or polysorbate-80 exacerbated colonic tumor development. Here, we investigate the impact of dietary emulsifiers consumption on cancer initiation and progression in a genetical model of intestinal adenomas. In APCmin mice, we observed that dietary emulsifiers consumption enhanced small-intestine tumor development in a way that appeared to be independent of chronic intestinal inflammation but rather associated with emulsifiers’ impact on the proliferative status of the intestinal epithelium as well as on intestinal microbiota composition in both male and female mice. Overall, our findings further support the hypothesis that emulsifier consumption may be a new modifiable risk factor for colorectal cancer (CRC) and that alterations in host–microbiota interactions can favor gastrointestinal carcinogenesis in individuals with a genetical predisposition to such disorders.

scholarly journals Rehydration before Application Improves Functional Properties of Lyophilized Lactiplantibacillus plantarum HAC03

2021 ◽  
Vol 9 (5) ◽  
pp. 1013
Author(s):  
Karina Arellano-Ayala ◽  
Juhwan Lim ◽  
Subin Yeo ◽  
Jorge Enrique Vazquez Bucheli ◽  
Svetoslav Dimitrov Todorov ◽  
...  
Keyword(s):  
Intestinal Tract ◽  
Food Additives ◽  
Nitrogen Compounds ◽  
Protein Nitrogen ◽  
Bacterial Surface ◽  
Freeze Dried ◽  
Immunomodulatory Properties ◽  
Gastro Intestinal Tract ◽  
The Impact ◽  
Active Formulation

Preservation of probiotics by lyophilization is considered a method of choice for developing stable products. However, both direct consumption and reconstitution of dehydrated probiotic preparations before application “compromise” the survival and functional characteristics of the microorganisms under the stress of the upper gastro-intestinal tract. We evaluated the impact of different food additives on the viability, mucin adhesion, and zeta potential of a freeze-dried putative probiotic, Lactiplantibacillus (Lp.) plantarum HAC03. HAC03-compatible ingredients for the formulation of ten rehydration mixtures could be selected. Elevated efficacy was achieved by the B-active formulation, a mixture of non-protein nitrogen compounds, sugars, and salts. The survival of Lp. plantarum HAC03 increased by 36.36% compared rehydration with distilled water (4.92%) after passing simulated gastro-intestinal stress conditions. Cell viability determined by plate counting was confirmed by flow cytometry. B-active formulation also influenced Lp. plantarum HAC03 functionality by increasing its adherence to a Caco-2 cell-line and by changing the bacterial surface charge, measured as zeta potential.Hydrophobicity, mucin adhesion and immunomodulatory properties of Lp. plantarum HAC03 were not affected by the B-active formulation. The rehydration medium also effectively protected Lp. plantarum ATCC14917, Lp. plantarum 299v, Latilactobacillus sakei (Lt.) HAC11, Lacticaseibacillus (Lc.) paracasei 532, Enterococcus faecium 200, and Lc. rhamnosus BFE5263.

scholarly journals Analysis of the Gastro-Intestinal Tract of Marine Mammals: A Multidisciplinary Approach with a New Multi-Sieves Tool

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1824
Author(s):  
Giorgia Corazzola ◽  
Matteo Baini ◽  
Carla Grattarola ◽  
Cristina Panti ◽  
Federica Marcer ◽  
...  
Keyword(s):  
Cause Of Death ◽  
Marine Mammals ◽  
Intestinal Tract ◽  
Multidisciplinary Approach ◽  
Sample Collection ◽  
Important Data ◽  
New Device ◽  
Specific Protocol ◽  
Specific Analysis ◽  
Gastro Intestinal Tract

Organs and content of the gastro-intestinal tract (GIT) of marine mammals are relevant for a variety of investigations and provide data to researchers from different fields. Currently used protocols applied to the GIT for specific analysis limit the possibility to execute other investigations and important information could be lost. To ensure a proper sample collection and a multidisciplinary investigation of the GIT of marine mammals, a new multi-sieves tool and a specific protocol have been developed. This new device and approach allowed the simultaneous sampling of the GIT and its content for the main investigations concerned. The samples collected during these preliminary trials were suitable to perform all the different research procedures considered in this work. The obtained results show that with a few and easy procedural adjustments, a multidisciplinary sampling and evaluation of the GIT of marine mammals is possible. This will reduce the risk of losing important data aimed at understanding the cause of death of the animal, but also biology and ecology of marine mammals, and other important data for their conservation and habitats management.

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