scholarly journals Relationship of Change in Plasma Clozapine/N-desmethylclozapine Ratio with Cognitive Performance in Patients with Schizophrenia

2020 ◽  
Vol 17 (11) ◽  
pp. 1158-1165
Author(s):  
Royun Park ◽  
Seoyoung Kim ◽  
Euitae Kim
Keyword(s):  
Multiple Regression ◽  
Cognitive Performance ◽  
Pearson Correlation ◽  
Plasma Concentrations ◽  
Negative Association ◽  
Stepwise Multiple Regression ◽  
Clozapine Treatment ◽  
Opposite Action ◽  
Relationship Of

Objective The clozapine/N-desmethylclozapine (NDMC) ratio is proposed to be used as a predictor of cognitive performance in clozapine-treated patients, as its principal metabolite, NDMC, has an opposite action with clozapine on the cholinergic system. The aim of this study is to determine whether clozapine has influence on cognitive performance in accordance with changes in the clozapine/NDMC in patients with schizophrenia.Methods The data of fifteen patients with schizophrenia, who had initial and follow-up assessments after starting clozapine treatment, were retrospectively collected. The assessments included clinical scale, cognitive battery, and pharmacological data including plasma concentrations of clozapine and NDMC. The data were analyzed with Pearson correlation and stepwise multiple regression analyses.Results ΔAttention/vigilance, Δsocial cognition, and Δcomposite score had a significant correlation with Δclozapine/NDMC ratio, while ΔWorking memory had correlation with Δclozapine concentration and ΔNDMC concentration, and Δsocial cognition had association with Δclozapine concentration. Multiple regression analysis showed that Δattention/vigilance had negative association with Δclozapine/NDMC ratio, Δworking memory had negative relation with Δclozapine concentration, and that Δsocial cognition had negative association with Δclozapine concentration.Conclusion This finding implicates that lowering the clozapine/NDMC ratio could enhance cognition in patients with schizophrenia treated with clozapine.

Follow-up of women with large-for-dates infants. Early insulin and C-peptide response to intravenous glucose, blood lipids and HLA-types

1981 ◽  
Vol 98 (3) ◽  
pp. 420-427 ◽  
Author(s):  
B. Persson ◽  
E. Möller ◽  
S. Thunell
Keyword(s):  
Multiple Regression ◽  
Plasma Concentrations ◽  
Insulin Response ◽  
Hla Antigens ◽  
Hla Typing ◽  
Inverse Association ◽  
Intravenous Glucose ◽  
C Peptide ◽  
Glucose Plasma

Abstract. In a previous study we determined the glucose disappearance rate (kt) in 129 newborn large-for-dates infants (LFD) born to mothers without known diabetes. Twenty-six infants (i.e. 20.6%) had elevated kt values similar to those in offspring of diabetic mothers. A follow-up study of 123 of these mothers was performed 7 years after delivery and included determination of early insulin and C-peptide response to intravenous glucose, plasma concentrations of 3-hydroxybutyrate, cholesterol, triglycerides, lipoproteins and HLA-typing. Two subjects had developed diabetes and altogether 14% had a kt below 1.0. Measures of the early insulin and C-peptide response to glucose were equally well correlated to maternal kt values (r = 0.40, P < 0.001). Measures of the early insulin and C-peptide responses were significantly correlated (r = 0.64, P < 0.001). The frequency distribution of HLA antigens were not different from normal and there was no association between HLA-B8 or B15 and impaired insulin response or glucose tolerance. Multiple regression and discriminate analysis of clinical and biochemical variables could not accurately identify women with high or low kt values. Multiple regression analysis using infant kt value as the dependent variable disclosed only a weak, but significant, inverse association to maternal insulin response to glucose at follow-up.

The Effect of Administrators’ Servant Leadership on the Excellence of Catholic School

2017 ◽  
Vol 7 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Saowanee Sirisookslip ◽  
Wallapha Ariratana ◽  
Tang keow Ngang
Keyword(s):  
Regression Analysis ◽  
Servant Leadership ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Catholic Schools ◽  
School Administrators ◽  
Pearson Correlation ◽  
Catholic School ◽  
Stepwise Multiple Regression ◽  
High Level

AbstractThe research was aimed to study the effect of school administrators’ servant leadership on the excellence of Catholic Schools under Nakhon Rarchasima Diocese. A total of 326 respondents consisting 61 school administrators and 265 teachers were involved in this study. A quantitative survey design using questionnaire as an instrument was utilized in this study. Descriptive and inferential statistics were used to analyze the data. Descriptive statistic used in this study were frequency, percentage, mean score and standard deviation whereas inferential statistic used were Pearson correlation coefficient and Stepwise multiple regression analysis. The findings of the study revealed that both the independent and dependent variables were at high level. In short, school administrators were not only highly implemented servant leadership and its components but also the level of excellence was at high level. The excellence level of Catholic schools was significantly affected by three components of school administrators’ servant leadership at significant level of 0.05. The significant predictors of the school excellence level were community establishment, trust, love, and having vision components of servant leadership. The coefficient relative rate of multiple regression analysis was 0.651 and coefficient prediction was 41.60 percent. Finally, this paper also provided recommendation and suggestions for future research. Keywords: Servant leadership; school administrators; school excellence; Catholic schools

scholarly journals The Influence of Self-efficacy and Activities of Daily Living on Depression among Elderly Nursing Home Residents

2018 ◽  
Vol 24 (4) ◽  
pp. 367-375 ◽  
Author(s):  
Myoung Sook Kim
Keyword(s):  
Nursing Home ◽  
Activities Of Daily Living ◽  
Multiple Regression ◽  
Self Efficacy ◽  
Daily Living ◽  
Pearson Correlation ◽  
Nursing Home Residents ◽  
The Elderly ◽  
Nursing Intervention ◽  
Stepwise Multiple Regression

Purpose: This purpose of this study was to examine the effects of self-efficacy and activities of daily living on the level of depression among elderly nursing home residents. Methods: A descriptive study was conducted using a self-reported questionnaires completed by 163 elderly. Data were analyzed using t-test, one-way ANOVA, Scheff? test, Pearson correlation coefficients, and multiple regression analysis using SPSS 20.0. Results: The mean score for depression was 9.24, for self-efficacy 3.19, and for activities of daily living 1.85. Stepwise multiple regression analyses were used to examine the influences of research variables. Activities of daily living and self-efficacy were significant predictors of depression. The model explained 24.0% of the variables. Conclusion: As a result of this study, the activities of daily living and self-efficacy were defined as an important influential on depression. Therefore, the development nursing intervention programs is needed to reduce depression levels in the elderly to enhance daily living activities and self-efficacy.

Relationship between Time Structure and Procrastination

1997 ◽  
Vol 80 (1) ◽  
pp. 211-215 ◽  
Author(s):  
Stephen J. Vodanovich ◽  
Hope M. Seib
Keyword(s):  
Multiple Regression ◽  
Undergraduate Students ◽  
Time Management ◽  
Zero Order ◽  
Time Structure ◽  
Stepwise Multiple Regression ◽  
Multiple Correlation ◽  
Effective Organization ◽  
The Relationship

The relationship between time structure and procrastination was investigated among 115 Irish undergraduate students. Significant negative zero-order correlations were found among scores for all five subscales of time structure and procrastination. A follow-up stepwise multiple regression indicated a significant multiple correlation ( R = .61) between all five time structure subscale scores and procrastination. Significant predictors of procrastination were scores on the Time Structure subscales of Effective Organization followed by Sense of Purpose. These results suggest that strategies focusing on time management in conjunction with existential approaches of psychotherapy may be an effective intervention for reducing procrastination.

Interests and Self-Efficacy as Predictors of Mathematics/Science-Based Career Choice

1994 ◽  
Vol 75 (2) ◽  
pp. 753-754 ◽  
Author(s):  
Michele M. Borget ◽  
Faith D. Gilroy
Keyword(s):  
Regression Analysis ◽  
Career Choice ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Self Efficacy ◽  
Stepwise Multiple Regression ◽  
Stepwise Multiple Regression Analysis ◽  
Relationship Of ◽  
The Relationship

This study examined the relationship of 125 college women's mathematical self-efficacy and interest in mathematics/science-based careers to the consideration of pursuing such careers. A stepwise multiple regression analysis indicated that interest alone was a significant predictor of career choice.

scholarly journals Predictive Factors of Diarrhea Preventive Practices by Caretakers

2019 ◽  
Vol 17 (2) ◽  
pp. 247-252
Author(s):  
Priya Pathak ◽  
Chokchai Munsawaengsub ◽  
Sutham Nanthamongkolchai
Keyword(s):  
Multiple Regression ◽  
Predictive Power ◽  
Family Income ◽  
Diarrheal Disease ◽  
Pearson Correlation ◽  
Univariate Analysis ◽  
Childhood Mortality ◽  
Wash Water ◽  
Stepwise Multiple Regression ◽  
Preventive Practices

Background: Diarrhea is a leading cause of childhood mortality globally as well as in Nepal. Data all around the world has shown the highest prevalence of diarrheal disease amongst 6-12 months old children. This paper aims to assess the existing diarrhea preventive practices carried out by caretakers of children from 6-12 months of age and their predicting factors in Chitwan district of Nepal.Methods: A cross -sectional survey was conducted among 384 caretakers of children aged 6-12 months from four different MCH clinics of Chitwan district, Nepal. Data were collected by using face- to-face interviews with structured questionnaires from April 15 to May 30, 2018. Univariate analysis, chi square, Pearson correlation and stepwise multiple regression analysis were the statistics used for data analysis. Results: The findings showed that only around one-fourth (22.7%) of the caretakers followed good diarrhea preventive practices. Stepwise multiple regression showed that age, monthly family income, knowledge, attitude and accessibility to WASH (water, sanitation and hygiene), could predict the diarrhea preventive practices of caretakers by only 20.5%. Accessibility to WASH (beta= 0.246) had the highest predictive power and age (beta= 0.015) had the least predictive power of diarrhea preventive practices amongst them. Conclusions: The findings of this study suggest that there is a definite need to promote diarrhea preventive practices. Local government and non-government organizations should establish activities to improve accessibility to WASH, caretaker’s attitude and caretaker’s knowledge in order to ultimately improve their preventive practices.Keywords: Caretakers; children; chitwan; diarrhea preventive practices; 6-12 months old; Nepal.

scholarly journals Predicting nurse's depression based on self-compassion and resilience

2021 ◽  
Author(s):  
Fateme-Sadat HOSSEINI ◽  
Farahnaz FARNIA ◽  
Saeed VAZIRI
Keyword(s):  
Multiple Regression ◽  
Pearson Correlation ◽  
Protective Role ◽  
Bachelor's Degree ◽  
Self Report ◽  
Limited Information ◽  
Self Compassion ◽  
Important Health ◽  
Relationship Of

Introduction: Depression is one of the most important health problems in nurses. Despite the obvious protective role of some human abilities against psychological problems, there is limited information about the predictive role of self-compassion and resilience with depression in nurses. The purpose of present study was to determine the relationship of self-compassion and resilience with nurses’ depression. Method: This descriptive correlational study was conducted on170 nurses working in Yazd Afshar Hospital selected by convenience sampling method. Data collection tool was a questionnaire, including demographic characteristics, Beck Depression, Neff Self-compassion, and Connor and Davidson resilience completed through self-report. The data were analyzed by SPSS using Pearson correlation coefficient and multiple regression analysis. Results: Most of the subjects were female (62.35%) and had bachelor’s degree. Mean ± standard deviation of depression, self- compassion, and resilience scores were72/17 ±28/8; 65/31±46/1; 65/33 ±06/1, respectively. There was a significant relationship between depression and self-compassion, as well as depression and resilience. Furthermore, multiple regression analyses showed that self-compassion and resilience can predict depression (R=0.627). Conclusion: The results indicated the importance and protective role of self-compassion and resilience against depression in nurses. Therefore, designing counseling systems and self-compassion and resilience educational programs are recommended to reduce the problems caused by the stressful conditions of the profession.

scholarly journals An Empirical Analysis of Correlation Between Technostress and Job Satisfaction: A Case of KPK, Pakistan

2013 ◽  
Vol 14 ◽  
pp. 9-15
Author(s):  
Asad Khan ◽  
Hamid Rehman ◽  
Shafiq -ur- Rehman
Keyword(s):  
Job Satisfaction ◽  
Regression Analysis ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Pearson Correlation ◽  
Three Dimensions ◽  
Public And Private ◽  
Relationship Of ◽  
Self Administered Questionnaire ◽  
Data Screening

The objective of this research was to explore an association between technostress and job satisfaction of university librarians in Khyber Pakhtoonkhwa (KPK), Pakistan. For that reason a self-administered questionnaire was used to gather the data from 148 librarians serving in 25 public and private sectors universities of KPK. The entire population (N=148) was selected as respondents because the population was accessible. For this study, 148 questionnaires were distributed and only 120 questionnaires were returned. However, after initial data screening, 116 questionnaires were ascertained as useable for further statistical analyses. Pearson correlation was calculated to investigate the correlation of technostress and job satisfaction. Multiple regression analysis was performed to test the three hypotheses between technostress dimensions and job satisfaction. Findings of this study show a negative but statistically significant relationship of three dimensions of technostress with job satisfaction. Based on multiple regression analysis-all the three hypotheses, (H1, H2, and H3) are supported. This study will be significant in controlling stress caused by technology and enhancing the level of job satisfaction among Pakistani university librarians. The study will equally contribute to the literature on relationship between technostress and job satisfaction. No identical previous studies were located on this topic in the context of Pakistani university librarianship.

scholarly journals Decisional procrastination of school-to-work transition: Personality correlates of career indecision

2015 ◽  
Vol 46 (1) ◽  
pp. 34-44 ◽  
Author(s):  
Augustyn Bańka ◽  
Aleksander Hauziński
Keyword(s):  
Multiple Regression ◽  
School To Work ◽  
Career Indecision ◽  
Stepwise Multiple Regression ◽  
Regression Analyses ◽  
School To Work Transition ◽  
Identity Statuses ◽  
Work Transition ◽  
Decisional Procrastination ◽  
Relationship Of

Abstract Procrastination as putting off until tomorrow what one had intended to do today is well-known tendency in everyday life. In an attempt to understand the character of procrastination in different life-domains, a large body of research has been accumulated over the last decades. This article was aimed to evaluate a specific decisional procrastination of school-to-work transition (SWT) that is treated as maturity postponement. Two studies are reported examining SWT procrastination defined as career indecision among Polish students graduating universities. In Study 1 (N=366), attitudinal and identity statuses were analyzed as correlates of career procrastination. A path analysis conducted for the model, which was aimed to explain the influence of career self-efficacy and occupational commitment on career indecision (dependent variable), revealed its very good fitness (RMSEA=.000). Those two independent variables explain 10% of career indecision variance. Stepwise multiple regression analyses conducted to ascertain relationship of five identity statuses (Brzezińska, Piotrowski, 2010) to procrastination measure (career indecision) showed that Commitment Making and Ruminative Exploration are strongest predictor variables. In study 2 (N=157), the stepwise multiple regression analyses conducted to ascertain the independent relationship of each of Big Five personality factor revealed that Neuroticism and Extraversion accounts of the most of explained variance of school-to-work transition procrastination.

Relationship of Extraversion, Neuroticism, Alienation, and Divorce Incidence with Pet-Ownership

1985 ◽  
Vol 57 (3) ◽  
pp. 868-870 ◽  
Author(s):  
Deborah Paden-Levy
Keyword(s):  
Multiple Regression ◽  
Parental Divorce ◽  
Demographic Variables ◽  
Personality Inventory ◽  
Stepwise Multiple Regression ◽  
Pet Ownership ◽  
Positive Correlation ◽  
Eysenck Personality Inventory ◽  
Relationship Of ◽  
Low Magnitude

100 freshman women completed the Eysenck Personality Inventory, the Alienation Scale, and a researcher-constructed questionnaire to determine the association of pet-ownership with extraversion, with neuroticism, with alienation, with incidence of parental divorce, and with several demographic variables. Pearson product-moment and point-biserial correlations rested for significance and a stepwise multiple regression were applied to the data. The predicted positive correlation between pet-ownership and extraversion was not found. Hypotheses predicting pet-ownership to be negatively correlated with neuroticism, alienation, and incidence of parental divorce were all supported by correlations of low magnitude.

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