scholarly journals Article Review: Coloration Biochemistry and Molecular Biology Between Polycystic Ovary Syndrome and Diabetes Mellitus Type 2

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Noora Wael Rasheed ◽  
Abeer Ali Marhoon
Keyword(s):  
Diabetes Mellitus ◽  
Multiple Testing ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Premenopausal Women ◽  
Ovary Syndrome ◽  
Indian Women ◽  
Reproductive Endocrine ◽  
Ovarian Syndrome

Polycystic ovarian syndrome is the most common reproductive endocrine disorder in premenopausal women Given the clinical overlap between PCOS and type 2 diabetes mellitus (T2DM), this research sought to investigate if genes associated with T2DM were similarly connected to PCOS vulnerability. In either the univariate or multivariate scenario, none of the 16 SNPs was significantly associated with Polycystic Ovarian Syndrome after Bonferroni correction for multiple testing. The nine T2DM genes investigated in this preliminary research may not be the main PCOS risk factors in Indian women. Our findings add to the absence of evidence of a link between T2DM genes and PCOS in Chinese and Caucasians, suggesting that this trend may be universal. To determine the exact significance of the diabetes genes, researchers will need to conduct extensive studies that involve women with T2DM and PCOS.

Prevalence of polycystic ovarian changes and polycystic ovary syndrome in premenopausal women with treated type 2 diabetes mellitus

2006 ◽  
Vol 86 (2) ◽  
pp. 405-410 ◽  
Author(s):  
Fahrettin Kelestimur ◽  
Kürşad Unluhizarci ◽  
Hür Baybuga ◽  
Hulusi Atmaca ◽  
Fahri Bayram ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Premenopausal Women ◽  
Ovary Syndrome

COMPLICATIONS OF PREGNANCY IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME

2011 ◽  
Vol 22 (3) ◽  
pp. 188-206
Author(s):  
MALLIKA AZIZIA ◽  
PAUL HARDIMAN
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Polycystic Ovaries ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
Ovarian Syndrome

Polycystic ovary syndrome (PCOS) is a common hormonal disorder affecting around 5–8% of women of reproductive age. It has a variable clinical spectrum including hyperandrogenism, menstrual abnormalities, polycystic ovaries and metabolic features like diabetes mellitus, obesity and dyslipidaemia. The manifestation of PCOS and its impact especially on reproductive function and pregnancy are profoundly affected by associated features of obesity/raised body mass index and metabolic syndrome.

Case Study of Polycystic Ovary Syndrome -An Overview

2021 ◽  
pp. 56-60
Author(s):  
Pratiksha Chitalkar ◽  
Rakesh Kumar Jha ◽  
Dhruba Hari Chandi
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Daily Basis ◽  
The Body ◽  
Ovary Syndrome ◽  
Indian Women ◽  
High Insulin ◽  
Ovarian Syndrome ◽  
Improve Health

Introduction: Polycystic ovarian syndrome (PCOS) is also known as polycystic ovarian disorder (POD). The disease is mainly metabolic (hyper androgenic) one. It usually affects women between the ages of 18 and 44. PCOS has no clear origin, although it seems to work at home. It is related to the effects of high levels of hormones in the body, such as high insulin levels. PCOS affects more than a million people in India each year. PCOS affects one in five Indian women (20%). Left untreated, the disease can lead to serious health problems. Conclusion: There is no permanent treatment for it since it is an irreversible syndrome/disease. The best way to improve health conditions is to change one's lifestyle and take drugs. One of the most effective methods is to make a healthy food/bad food chart and stick to it with exercise and medicine on a daily basis.

scholarly journals Prevalence of polycystic ovarian syndrome among selected group of Sudanese housewives with infertility disorders

2019 ◽  
Vol 2 (01) ◽  
Author(s):  
Mohammed A.Gafoor A.Gadir ◽  
Mohammed Omer Mohammed Hussein ◽  
Mosab Nouraldein Mohammed Hamad
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Clinical Symptoms ◽  
Polycystic Ovary ◽  
Pancreatic Beta Cell ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Cell Dysfunction ◽  
Increased Risk ◽  
Ovarian Syndrome

Polycystic ovary syndrome (PCOS), also recognized as the Stein-Leventhal syndrome, is one of the most widespread endocrinopathies between women of reproductive age. Hyperinsulinemia in mixture with pancreatic beta cell dysfunction consequences in an increased risk of numerous illnesses, counting type 2 diabetes, hypertension, dyslipidemia, endothelial dysfunction, atherosclerosis and cardiovascular diseases. Insulin also stimulates the theca cells of the ovary to create excessive testosterone, which is accountable for the clinical symptoms of hyperandrogenism

The Impact of Obesity on Incidence of Type 2 Diabetes Mellitus (T2DM) among Women with Polycystic Ovary Syndrome (PCOS)

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1612-P
Author(s):  
NADIRA SULTANA KAKOLY ◽  
ARUL EARNEST ◽  
HELENA TEEDE ◽  
LISA MORAN ◽  
DEBORAH LOXTON ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
The Impact

scholarly journals Endocrinological and metabolic characteristics in patients who are non-obese and have polycystic ovary syndrome and different types of a family history of type 2 diabetes mellitus

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110166
Author(s):  
Yuan Wang ◽  
Hua Gao ◽  
Wen Di ◽  
Zhuowei Gu
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
History Of ◽  
Second Degree

Objective We aimed to investigate whether patients with polycystic ovary syndrome (PCOS) and a family history (FH) of type 2 diabetes mellitus (T2DM) are at increased risk of endocrinological and metabolic abnormalities, and whether this risk differs between first-degree and second-degree relatives, and between maternal and paternal transmission. Methods A total of 680 patients with PCOS were enrolled in this retrospective, single-center study. Endocrine and glycolipid metabolism parameters were compared. Results The free androgen index (FAI), and levels of fasting blood glucose (FBG), fasting insulin (FINS), homeostatic model assessment-insulin resistance (HOMA-IR), total cholesterol (TC), and low-density lipoprotein cholesterol were significantly higher, whereas sex hormone binding globulin (SHBG) levels were significantly lower in patients with PCOS and a FH of T2DM. In patients with PCOS with a FH of T2DM in first-degree relatives, age and levels of FBG, FINS, and HOMA-IR were significantly higher than those who had a FH of T2DM in second-degree relatives. A maternal history of T2DM was associated with a higher body mass index, FAI, and TG levels, and lower SHBG levels. Conclusions Patients with PCOS and a FH of T2DM have more severe hyperandrogenism and metabolic disorders, especially in those with maternal transmission.

scholarly journals Adnexal Torsion during Pregnancy after Oocyte In Vitro Maturation and Intracytoplasmic Sperm Injection Cycle

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Simone Giulini ◽  
Giulia Dante ◽  
Susanna Xella ◽  
Antonio La Marca ◽  
Tiziana Marsella ◽  
...  
Keyword(s):  
In Vitro Maturation ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Adnexal Torsion ◽  
Term Pregnancy ◽  
Ovary Syndrome ◽  
Clinical Disorder ◽  
Injection Cycle ◽  
Ovarian Syndrome

We report a case of right adnexal torsion during pregnancy after an oocyte in vitro maturation and intracitoplasmic sperm injection cycle in patient with polycystic ovary syndrome. A 31-year-old woman with a typical clinical disorder of polycystic ovarian syndrome was included in an oocyte in vitro maturation program. Right adnexal torsion occurred two days after embryo transfer, and laparoscopy detorsion was successfully performed with preservation of adnexa. The patient had a full-term pregnancy and delivered a healthy infant at 40 weeks of gestation. To our knowledge this is the first report of adnexal torsion after an oocyte in vitro maturation and intracitoplasmic sperm injection program.

Pharmacogenetics of metformin in polycystic ovary syndrome and type 2 diabetes mellitus

2021 ◽  
Author(s):  
Moritz Strasser ◽  
Natascha Schweighofer ◽  
Anna Obermayer ◽  
Valentin Borzan ◽  
Christoph Haudum ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome
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