Acceleration time to Ejection time ratio in fetal pulmonary artery system can predict neonatal respiratory disorders in gestational diabetic mellitus women

2021 ◽  
pp. 1-11
Author(s):  
Shuya Wang ◽  
Yueheng Wang ◽  
Man Gao ◽  
Yongpan Tan
Keyword(s):  
Blood Flow ◽  
Pulmonary Artery ◽  
Pregnant Women ◽  
Artery Blood Flow ◽  
Diabetic Mellitus ◽  
Ejection Time ◽  
Respiratory Disorders ◽  
Acceleration Time ◽  
Left And Right ◽  
Neonatal Respiratory Disorders

BACKGROUND: Few researches studied fetal pulmonary pulse wave doppler and the clinical end point disorders in gestational diabetic mellitus (GDM) cohort. OBJECTIVE: To investigate fetal pulmonary artery acceleration time to ejection time ratio (PATET) in the prediction of neonatal respiratory disorders (NRD). METHODS: 238 pregnant women diagnosed with GDM who attended our hospital between February 2018 and March 2020 were retrospectively included. Fetal pulmonary artery Doppler wave measurements were recorded, including main, left and right pulmonary artery blood flow, and left and right peripheral pulmonary artery blood flow. Acceleration time (At)/ejection time (Et) were calculated. RESULTS: 183 GDM pregnant women and neonates were divided into NRD(+)(n = 42) and NRD(–) group (n = 141). 16 cases were neonatal pneumonia (NP) within 28 days after birth in NRD(+) group. The area under curve (AUC) of left peripheral pulmonary artery acceleration time to ejection time (LPPATET) was 0.967 (95% CI: 0.927∼1.000, P <  0.001) and the AUC of right peripheral pulmonary artery acceleration time to ejection time (RPPATET) was 0.967 (95% CI: 0.927∼1.000, P <  0.001), indicating that LPPATET and RPPATET are both predictors for NRD. The results of interobserver variabilty and intraobserver variability showed a good consistency. CONCLUSIONS: The At/Et of fetal peripheral pulmonary artery (PPA) in GDM women may be predictors for NRD, and the indicator can provide assistance in clinical management of diabetes pregnant patients.

scholarly journals Echocardiographic Doppler Estimation of Pulmonary Artery Pressure in Critically Ill Patients with Severe Hypoxemia

2008 ◽  
Vol 108 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Bélaïd Bouhemad ◽  
Fabio Ferrari ◽  
Kris Leleu ◽  
Charlotte Arbelot ◽  
Qin Lu ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Blood Flow ◽  
Pulmonary Artery ◽  
Pulmonary Artery Catheter ◽  
Pulmonary Artery Pressure ◽  
Artery Blood Flow ◽  
Severe Hypoxemia ◽  
Acceleration Time ◽  
Artery Pressure ◽  
Doppler Study

Background In spontaneously breathing cardiac patients, pulmonary artery pressure (PAP) can be accurately estimated from the transthoracic Doppler study of pulmonary artery and tricuspid regurgitation blood flows. In critically ill patients on mechanical ventilation for acute lung injury, the interposition of gas between the probe and the heart renders the transthoracic approach problematic. This study was aimed at determining whether the transesophageal approach could offer an alternative. Methods Fifty-one consecutive sedated and ventilated patients with severe hypoxemia (arterial oxygen tension/fraction of inspired oxygen &lt; 300) were prospectively studied. Mean PAP measured from the pulmonary artery catheter was compared with several indices characterizing pulmonary artery blood flow assessed using transesophageal echocardiography: preejection time, acceleration time, ejection duration, preejection time on ejection duration ratio, and acceleration time on ejection duration ratio. In a subgroup of 20 patients, systolic PAP measured from the pulmonary artery catheter immediately before withdrawal was compared with Doppler study of regurgitation tricuspid flow performed immediately after pulmonary artery catheter withdrawal using either the transthoracic or the transesophageal approach. Results Weak and clinically irrelevant correlations were found between mean PAP and indices of pulmonary artery flow. A statistically significant and clinically relevant correlation was found between systolic PAP and regurgitation tricuspid flow. In 3 patients (14%), pulmonary artery pressure could not be assessed echocardiographically. Conclusions In hypoxemic patients on mechanical ventilation, mean PAP cannot be reliably estimated from indices characterizing pulmonary artery blood flow. Systolic PAP can be estimated from regurgitation tricuspid flow using either transthoracic or transesophageal approach.

scholarly journals Fetal Thoracic Circumference and Lung Volume and Their Relation to Fetal Size and Pulmonary Artery Blood Flow

2021 ◽  
Author(s):  
Katarina Hilde ◽  
Karin C. Lødrup Carlsen ◽  
Karen Eline Stensby Bains ◽  
Hrefna Katrín Gudmundsdóttir ◽  
Christine Monceyron Jonassen ◽  
...  
Keyword(s):  
Blood Flow ◽  
Pulmonary Artery ◽  
Lung Volume ◽  
Artery Blood Flow ◽  
Fetal Size

Pulmonary artery blood flow and hemodynamics

1996 ◽  
pp. 229-324
Author(s):  
Belinda Ha ◽  
William Henry ◽  
Carol Lucas ◽  
Hsing-Wen Sung ◽  
Ajit Yoganathan
Keyword(s):  
Blood Flow ◽  
Pulmonary Artery ◽  
Artery Blood Flow

Analysis of pulsatile pulmonary artery blood flow in the unanesthetized dog

1981 ◽  
Vol 50 (4) ◽  
pp. 805-813 ◽  
Author(s):  
J. W. Hammon ◽  
P. K. Smith ◽  
P. A. McHale ◽  
K. M. Vanbenthuysen ◽  
R. W. Anderson
Keyword(s):  
Blood Flow ◽  
Pulmonary Artery ◽  
Artery Blood Flow

Alterations in Segmentary Branch Pulmonary Artery Blood Flow Velocimetry in Fetuses of Diabetic Mothers

2004 ◽  
Vol 23 (3) ◽  
pp. 339-345 ◽  
Author(s):  
Eyal Sivan ◽  
Boaz Weisz ◽  
Nitzan Shteinman ◽  
Eyal Schiff ◽  
Shlomo Lipitz ◽  
...  
Keyword(s):  
Blood Flow ◽  
Pulmonary Artery ◽  
Artery Blood Flow ◽  
Branch Pulmonary Artery ◽  
Flow Velocimetry ◽  
Diabetic Mothers

scholarly journals An Ascending Aortic Haemodynamic Comparison Between Normotensive and Hypertensive Subjects

2018 ◽  
Vol 2 (1) ◽  
pp. 16
Author(s):  
Vijay Kumar Narayana ◽  
Rajeev Sharma ◽  
Niranjan Murthy
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Ejection Fraction ◽  
Pressure Gradient ◽  
Aortic Blood Flow ◽  
Ejection Time ◽  
Acceleration Time ◽  
Aortic Blood ◽  
Ascending Aortic Diameter ◽  
Deceleration Time

<p><strong>Background:</strong> Systemic hypertension, a common disorder with potentially serious complications, exerts ill effects through structural and functional modifications of arterial wall. Haemodynamics play an important role in the development of atherosclerosis. Local hemodynamic temporal pressure and wall shear stress are important for understanding the mechanisms leading to various complications in cardiovascular function.</p><p><strong>Objectives:</strong> Since we could not find such a study in literature involving Indian population, this prompted us to investigate and establish the relationship between the blood pressure and the ascending aortic pulse wave parameters in normal individuals and compare the same with hypertensives.</p><p><strong>Material and Methods:</strong> A case control study was done in a tertiary care hospital involving 25 hypertensive parents and further compared with 25 normotensive subjects of same age group acting as control. The GE ̶ P 100 Doppler echocardiography machine was used to study acceleration time, deceleration time, ejection time, ejection fraction, peak flow velocity and pressure gradient in hypertensives and compared the same with age matched normotensive. Also ascending aortic diameter was mapped at the annulus.</p><p><strong>Results:</strong> The results of our study confirmed our assumption that in hypertensive the ascending aortic haemodynamic parameters are abnormal and both systolic and diastolic blood pressure does exert a statistically significant influence on the Doppler parameters of ascending aorta. The acceleration time, deceleration time, pressure gradient and ejection time showed statistically significant increase in hypertensives when compared to normotensive. At the same time the ejection fraction and the ascending aortic diameter showed a statistically significant decrease than normotensive.</p><p><strong>Conclusion:</strong> We would conclude to say that the Doppler parameters of ascending aortic blood flow are abnormal in hypertensives. This altered haemodynamics may lead to further ill effects by way of altered peripheral haemodynamics. This Doppler evaluation of ascending aortic blood flow can be developed as a clinical tool for evaluating hypertensives and assessing the benefit of treatment of hypertension.</p>

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