scholarly journals Inbreeding and Mortality Risk in a Captive Population of Mhorr Gazelle (Nanger dama mhorr)

2016 ◽  
pp. 159-167
Author(s):  
Ana Marquiza Quilicot ◽  
Roswitha Baumung
Keyword(s):  
Mortality Risk ◽  
Management Practices ◽  
Reference Population ◽  
Effective Number ◽  
Inbreeding Coefficients ◽  
In Captivity ◽  
Weaning Age ◽  
Efficient Breeding ◽  
Inbreeding Level ◽  
The Individual

This study aimed to evaluate the genetic variation and examine the association of inbreeding level on mortality risk (at days 7, 30 and 180 – weaning age) of Mhorr gazelle in captivity for the year 1969–2000 as recorded in the studbook record kept by Australasian Regional Association of Zoological Parks and Aquaria (ARAZPA). The effective number of founders, ancestors and founder genomes was found to be 3.42, 3, and 1.44 for the studied reference population. The reference population is composed of animals which are alive, with known parents and known sex. Animals that are less than 10 years old (based on birth dates up to 2008) with no remarks on its death are considered alive. The population may not have experienced a severe bottleneck, as the values on the effective number of founders and ancestors are almost equal. However, the effective number of founder genomes is low, which demonstrates gene loss due to genetic drift. The mean inbreeding coefficients of the individual, sire and dam were found to be 0.2971 ± 0.1043, 0.2300 ± 0.1141 0.2339 ± 0.1070, respectively. The maximum inbreeding level of the population is 0.5247 (52.47%). This means that parent–offspring or full-sib mating must have happened. The increase in inbreeding level of an individual was found to be significantly associated (p<0.10) with an increase in p mortality risk at day 180 or weaning age. Increasing inbreeding level of sires was found to be significantly associated with increasing risk in mortality at day 30, which indicates that inbred parents also can influence the survival of an offspring. Efficient breeding programs are as important for decreasing mortality in captive populations, as the provision of optimum zoo management practices.

scholarly journals Rank-invariant estimation of inbreeding coefficients

Heredity ◽  
2021 ◽  
Author(s):  
Qian S. Zhang ◽  
Jérôme Goudet ◽  
Bruce S. Weir
Keyword(s):  
Genetic Data ◽  
Reference Population ◽  
Inbreeding Coefficient ◽  
Allele Sharing ◽  
Ancestral Allele ◽  
1000 Genomes ◽  
Inbreeding Coefficients ◽  
Identical By Descent ◽  
Invariant Estimation ◽  
The Individual

AbstractThe two alleles an individual carries at a locus are identical by descent (ibd) if they have descended from a single ancestral allele in a reference population, and the probability of such identity is the inbreeding coefficient of the individual. Inbreeding coefficients can be predicted from pedigrees with founders constituting the reference population, but estimation from genetic data is not possible without data from the reference population. Most inbreeding estimators that make explicit use of sample allele frequencies as estimates of allele probabilities in the reference population are confounded by average kinships with other individuals. This means that the ranking of those estimates depends on the scope of the study sample and we show the variation in rankings for common estimators applied to different subdivisions of 1000 Genomes data. Allele-sharing estimators of within-population inbreeding relative to average kinship in a study sample, however, do have invariant rankings across all studies including those individuals. They are unbiased with a large number of SNPs. We discuss how allele sharing estimates are the relevant quantities for a range of empirical applications.

Analysis of the inbreeding level in the Polish population of the Alpine Dachsbracke dog breed in the years 2000-2016

2018 ◽  
Vol 14 (3) ◽  
pp. 9-18
Author(s):  
Elżbieta Bednarek ◽  
Anna Sławińska ◽  
Sławomir Mroczkowski
Keyword(s):  
Trend Analysis ◽  
Inbreeding Coefficient ◽  
Polish Population ◽  
Inbreeding Coefficients ◽  
The Mean ◽  
Dog Breed ◽  
Related Individuals ◽  
Inbreeding Level ◽  
The Individual

The aim of the study was to analyse the level of inbreeding in the Alpine Dachsbracke dog breed. The research was conducted using pedigrees of 405 individuals of this breed (195 male and 210 female), born in the years 2000-2016. The inbreeding coefficients (Fx) were estimated based on four-generation pedigrees. The individual inbreeding coefficients ranged from 0% to 25%. The average inbreeding coefficient for the population was 2.25% and did not differ between sexes (P>0.05). For 49.4% of individuals, the mean Fx value was 4.55%. The Fx values between years of birth were highly significant (P<0.0001). The trend analysis showed no significant changes in Fx during the period analysed. The mean inbreeding coefficient in the Polish population of Alpine Dachsbracke dogs was not high, but attention should be paid to the inbreeding coefficients of certain individuals, and mating of closely related individuals should be avoided.

scholarly journals Some Genetic and Environmental Effects on Equine Asthma in Polish Konik Horses

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2285
Author(s):  
Alicja Borowska ◽  
Daria Wolska ◽  
Artur Niedzwiedz ◽  
Hieronim Borowicz ◽  
Zbigniew Jaworski ◽  
...  
Keyword(s):  
Current Knowledge ◽  
Nasal Discharge ◽  
Relationship Matrix ◽  
Basic Symptoms ◽  
Asthma Morbidity ◽  
Inbreeding Coefficients ◽  
Chi Squared ◽  
Equine Asthma ◽  
Inbreeding Level ◽  
The Individual

Current knowledge of the genetic and environmental backgrounds of equine asthma seems to be insufficient, especially for primitive horse breeds. The main objectives of this study were to estimate the effects of sex, birth period, stud, parentage line and inbreeding on asthma morbidity in Polish Konik horses. Records of 274 horses (housed in two studs) were analysed. These animals were allocated to maternal and paternal lines. Individual inbreeding coefficients were extracted from the additive relationship matrix. Horses underwent diagnosis based on observation of the basic symptoms (high frequency of coughing and excessive nasal discharge). Subsequently, some horses (28 individuals) were clinically examined to confirm the earlier observations. Generally, no significant effects of parentage line on heaves morbidity were identified by the use of logistic regression, although the Pearson’s chi-squared test had shown that individuals of some maternal and paternal lines had a predisposition to severe equine asthma. It was concluded that the individual inbreeding level is not associated with the incidence of EA, but a significant effect of the maternal inbreeding coefficient may be observed. It was also found that there is some variability in the incidence of this disease between studs.

scholarly journals Genetic Structure Analysis of Tatra Shepherd Dog Population From Tatra Mountain Region

2015 ◽  
Vol 15 (2) ◽  
pp. 323-335 ◽  
Author(s):  
Joanna Kania-Gierdziewicz ◽  
Maciej Gierdziewicz ◽  
Bartłomiej Budzyński
Keyword(s):  
Genetic Structure ◽  
Mountain Region ◽  
Effective Number ◽  
Total Contribution ◽  
Inbreeding Coefficients ◽  
Population Average ◽  
Region Data ◽  
Relationship Coefficient ◽  
Inbreeding Level ◽  
Almost All

Abstract The aim of the work was to analyze the genetic structure of the population of Tatra Shepherd dogs, registered in branches of Polish Kennel Club from Tatra Mountain Region. Data were pedigrees of 102 Tatra Shepherd dogs (33 males and 69 females) born between 1994 and 2011. Inbreeding and relationship coefficients, as well as effective number of founders and ancestors, were calculated. These statistics give the picture of genetic diversity of the population. Average inbreeding coefficient was 7.17%, whereas average relationship coefficient was 18.20%. The number of inbred animals and the mean FX values steadily increased over time. Twenty-six of 80 inbred animals had inbreeding coefficients higher than 10%. The effective number of founders was relatively high in relation to the population size (the effective number of ancestors was four times lower) and both were similar to the results of studies of other authors on different dog breeds. The total contribution of only 4 ancestors was enough to explain 50% of the gene pool of the population. Therefore, mating of related animals should be avoided in order to prevent the further increase of inbreeding level, because almost all Polish and foreign Tatra Shepherd dogs living now originate from the population under study.

scholarly journals Leptospirosis in Ruminants in Yogyakarta, Indonesia: A Serological Survey with Mixed Methods to Identify Risk Factors

2021 ◽  
Vol 6 (2) ◽  
pp. 84
Author(s):  
Dyah Ayu Widiasih ◽  
Johanna Frida Lindahl ◽  
Wayan T. Artama ◽  
Adi Heru Sutomo ◽  
Pande Made Kutanegara ◽  
...  
Keyword(s):  
Risk Factor ◽  
Management Practices ◽  
Small Ruminants ◽  
Case Fatality ◽  
Open Water ◽  
Serum Samples ◽  
Public Health Importance ◽  
Group Discussions ◽  
The Individual ◽  
And Behavior

Leptospirosis is a zoonotic disease occurring worldwide with reproductive symptoms and production losses in livestock, while humans can suffer fatal renal failure. In Yogyakarta Special Province, Indonesia, there have been several outbreaks with high case fatality, demonstrating the public health importance, but there is limited understanding of the epidemiology. This study used an EcoHealth approach to ensure transdisciplinarity and community participation. Seroprevalence of Leptospira in animals was studied between October 2011 and May 2013 in 15 villages. Serum samples from 1404 cattle and 60 small ruminants were screened by a Microscopic Agglutination Test (MAT), first in pools, and then the individual positive samples were identified. Focus group discussions including farmers, village officials, and official stakeholders were used to explore knowledge and behavior of zoonotic diseases, particularly leptospirosis. Two small ruminants were seropositive for Leptospira icterohemorrhagiae. From the cattle, 3.7% were seropositive, and the most common serovars were Leptospira hardjo, followed by L. icterohemorrhagiae. Out of all farms, 5.6% had at least one positive cattle. Risk factor analyses showed that the risk of the farm being seropositive increased if the farmer used water from an open source, or if farming was not the main occupation. This study showed the presence of Leptospira spp. in ruminants in Yogyakarta and identified use of open water as a risk factor for the livestock. We also observed that the knowledge related to leptospirosis was low, and risky farm management practices were commonly employed.

scholarly journals Research on the Relationship between Shared Leadership and Individual Creativity-Qualitative Comparative Analysis on the Basis of Clear Set

2021 ◽  
Vol 13 (10) ◽  
pp. 5445
Author(s):  
Muyun Sun ◽  
Jigan Wang ◽  
Ting Wen
Keyword(s):  
Comparative Analysis ◽  
Environmental Factors ◽  
Shared Leadership ◽  
Management Practices ◽  
Qualitative Comparative Analysis ◽  
Necessary Condition ◽  
The Individual ◽  
The Impact ◽  
The Relationship ◽  
Sufficient And Necessary Condition

Creativity is the key to obtaining and maintaining competitiveness of modern organizations, and it has attracted much attention from academic circles and management practices. Shared leadership is believed to effectively influence team output. However, research on the impact of individual creativity is still in its infancy. This study adopts the qualitative comparative analysis method, taking 1584 individuals as the research objects, underpinned by a questionnaire-based survey. It investigates the influence of the team’s shared leadership network elements and organizational environmental factors on the individual creativity. We have found that there are six combination of conditions of shared leadership and organizational environmental factors constituting sufficient combination of conditions to increase or decrease individual creativity. Moreover, we have noticed that the low network density of shared leadership is a sufficient and necessary condition of reducing individual creativity. Our results also provide management suggestions for practical activities during the team management.

Evaluation of the sensitivity of faecal sampling for detection of monophasic Salmonella Typhimurium and other Salmonella in cattle and pigs

2014 ◽  
Vol 143 (8) ◽  
pp. 1681-1691 ◽  
Author(s):  
M. E. ARNOLD ◽  
R. J. GOSLING ◽  
F. MARTELLI ◽  
D. MUELLER-DOBLIES ◽  
R. H. DAVIES
Keyword(s):  
Faecal Sample ◽  
Management Practices ◽  
Age Groups ◽  
Farm Animals ◽  
Infection Prevalence ◽  
Sample Type ◽  
Sample Data ◽  
Using Data ◽  
The Individual ◽  
Positive Groups

SUMMARYThere has been a rapid rise in the prevalence of cases of monophasic Salmonella Typhimurium (mST) in both humans and farm animals, and it has been found in pigs, cattle and poultry. It is therefore vital to have a good understanding of how to efficiently detect infected farms. The objective of this project was to determine sample type sensitivity in the detection of Salmonella to detect infected groups of animals on both pig (breeder, grower and finisher sites) and cattle (beef and dairy) farms, using data collected from a study investigating farms that were positive for mST, and to explore any variation between different age groups and management practices. A Bayesian approach in the absence of a gold standard was adopted to analyse the individual and pooled faecal sample data collected from each epidemiological group on each of the farms. The sensitivity of pooled sampling depended on the prevalence of infection in the group being sampled, with a higher prevalence leading to higher sensitivity. Pooled sampling was found to be more efficient at detecting positive groups of animals than individual sampling, with the probability of a random sample from a group of animals with 5% prevalence testing positive being equal to 15·5% for immature pigs (3·6% for an individual faecal sample, taking into account the sensitivity and infection prevalence), 7·1% for adult pigs (1·2% for individual sampling), 30% for outdoor cattle (2% for individual sampling) and 34% for indoor cattle (1% for individual sampling). The mean prevalence of each epidemiological group was higher in outdoor farms than indoor for both pigs and cattle (mean within-farm prevalence of 29·4% and 38·7% for outdoor pigs and cattle, respectively, compared to 19·8% and 22·1% for indoor pigs and cattle)

Assessment of the genetic variability using pedigree analysis of the Sahiwal breed in Kenya

2016 ◽  
Vol 59 ◽  
pp. 7-14 ◽  
Author(s):  
S. Mwangi ◽  
T.K. Muasya ◽  
E.D. Ilatsia ◽  
A.K. Kahi
Keyword(s):  
Genetic Variability ◽  
Genetic Drift ◽  
Reference Population ◽  
Pedigree Analysis ◽  
Breeding Strategy ◽  
Progeny Testing ◽  
Founding Population ◽  
Effective Selection ◽  
Inbreeding Level ◽  
Year 2000

Summary Pedigree analysis using genealogical information of 18 315 animals born between 1949 and 2008 was done to quantify genetic variability of the Sahiwal population in Kenya. Generation intervals for sire pathways were longer than dam pathways and increased over year periods, from about 4–16 years. The later was due to use of old bulls for breeding in the last 2 year groups and cessation of progeny testing in the year 2000. Average inbreeding level in last year period studied was 1.2 percent. Genetic variability of the population as assessed based on gene origin statistics decreased over the years. The ratio of effective number of founders to founders of 0.06 showed unequal contribution of founders to the reference population. However, since the founding population, ancestors contributed equally as shown by the ratio of f e/f a of 0.94, which could also be due to lack of effective selection in this population. The ratio of f g/f a of 0.63 indicated genetic loss of genetic variability occurred through genetic drift in the Kenyan Sahiwal population. The small number of ancestors (16) that accounted for 50 percent of the total variation in the reference population suggested overuse of a small number of some animals as parents over generations. The smaller ratio of f g/f e compared with f a/f e also confirms loss of genetic variability in the population by genetic drift than bottlenecks. Therefore the breeding strategy for the Sahiwal population in Kenya should incorporate tools that balance rate of genetic gain and the future rate of inbreeding.

‘Persistence and Silence: A Narrative Analysis of Employee Responses to Organisational Change’

2003 ◽  
Vol 8 (4) ◽  
pp. 73-87 ◽  
Author(s):  
Melanie Bryant
Keyword(s):  
Narrative Analysis ◽  
Workplace Violence ◽  
Management Practices ◽  
Resistance To Change ◽  
Organisational Change ◽  
Original Intent ◽  
Career Opportunities ◽  
Response To Change ◽  
The Individual ◽  
Employee Responses

This article is concerned with how employees talk about organisational change and focuses specifically on how employees discuss reactions and responses to change through the construction of narratives. Employees included in this study suggest that the use of voice as an attempt to inform managers of their discontent, or remaining silent and passive are the most common responses to organisational change. Within sociology and management literature, voice has been considered as a constructive response to change, providing invaluable feedback to managers about declining conditions or performance lapses. Alternatively, remaining silent or passive has been documented as a weak strategy in which the individual renounces control and forms a dependency relationship with powerful groups such as managers. The primary aim of this paper is to challenge the argument that voice is a constructive response to change and suggest that voice is likely to be perceived as destructive, thus leading to the removal of responsibilities and career opportunities. Furthermore, this paper argues that silence is the more constructive response to change, which is documented in this research as leading to the advancement of careers. Relationships between the way employees respond to organisational change and the type of narrative that they construct is also discussed. Those who report remaining silent construct ‘conversion stories’ suggesting that organisational change provided a turning point in which employees could embrace management practices and gain career advancement. Alternatively, those who reported using voice construct ‘atrocity tales’ in which change is associated with stories of workplace bullying, removal of career opportunities and workplace violence. These narratives suggest that the use of voice as a response to change is more complex than its original intent and explanation in the literature, providing challenges for researchers in understanding where voice as a constructive response ends and where resistance to change begins.

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