scholarly journals Hematological Changes and Reference Intervals in Hanwoo Calves during the First 28 Weeks of Life

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1806
Author(s):  
Ui-Hyung Kim ◽  
Seung-Hwan Lee ◽  
Sang-Rae Cho ◽  
Sung-Sik Kang ◽  
Shil Jin ◽  
...  
Keyword(s):  
Hemoglobin Concentration ◽  
Reference Intervals ◽  
Mean Corpuscular Hemoglobin ◽  
Blood Cell Count ◽  
Platelet Volume ◽  
Adult Cattle ◽  
Male And Female ◽  
Analytic Process ◽  
Process Work ◽  
Hematological Changes

Hematological reference intervals must consider several parameters, including genotype, age, sex, management, and analytic process. Work is needed to evaluate hematological changes specifically in Hanwoo calves and according to calf sex. Therefore, in this study, we sought to confirm the complete blood cell count (CBC) reference intervals in Hanwoo calves, to monitor changes in hematologic values in Hanwoo calves from birth until 28 weeks of life, and to compare the hematologic values of male and female calves. A total of 35 male calves and 35 female calves was studied. Calf blood was sampled at multiple intervals from the time of birth until 28 weeks of age (including within 6 h of birth and at 2 days, 7 days, and 4 weeks and then at 4-week intervals through 28 weeks). In addition, blood samples were collected from 210 clinically healthy pregnant Hanwoo cows to establish CBC reference intervals for adult cattle. There were significant differences in the results of the cows and calves in all 14 parameters considered. The CBC reference intervals of the calves were wider than those of the cows in all parameters except mean corpuscular volume, mean corpuscular hemoglobin concentration, and mean platelet volume. We also identified differences from birth through 28 weeks between male and female calves at only some ages and some parameters. These results suggest that CBC reference intervals specific to Hanwoo calves are necessary for accurate diagnosis of calf diseases.

Hematological Changes and Severity of Aggression in Black and White Forensic Patients

1993 ◽  
Vol 73 (3_suppl) ◽  
pp. 1105-1106 ◽  
Author(s):  
Reuben T. Spitz ◽  
Hilliard G. Foster ◽  
Marc Hillbrand
Keyword(s):  
White Male ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Blood Cell Count ◽  
Corpuscular Hemoglobin ◽  
Mean Values ◽  
Forensic Patients ◽  
Black And White ◽  
Red Blood Cell Count ◽  
Hematological Changes

Analysis of hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin concentration, and red blood-cell count for a group of 46 black and 59 white male forensic patients showed significant hematological differences between the groups, with white patients demonstrating higher mean values for all four measures.

Narrowed reference intervals for complete blood count in a multiethnic population

2019 ◽  
Vol 57 (9) ◽  
pp. 1382-1387
Author(s):  
Seungok Lee ◽  
Chui Mei Ong ◽  
Yu Zhang ◽  
Alan H.B. Wu
Keyword(s):  
San Francisco ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hemoglobin Concentration ◽  
Reference Intervals ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Multiethnic Population ◽  
Race Ethnicity ◽  
Eosinophil Counts

Abstract Background Biological variation studies have shown that the complete blood count (CBC) has narrow within-individual variation and wide group variation, indicating that the use of reference intervals (RIs) is challenging. The aim of this study was to examine differences in CBC RIs according to race/ethnicity in a multiethnic population at a hospital in San Francisco in hopes of improving the medical utility of CBC testing. Methods Subject data were obtained by screening CBC results from the medical records of outpatients meeting certain criteria who visited Zuckerberg San Francisco General Hospital from April 2017 to January 2018. From these records, sex- and race/ethnicity-specific CBC RIs were calculated as the 2.5th to 97.5th percentiles. Results From a total of 552 subjects, 47.9% were male (65 White, 50 Black, 71 Hispanic and 54 Asian) and 52.1% were female (51 White, 39 Black, 122 Hispanic and 72 Asian). The RIs of neutrophil, lymphocyte and eosinophil counts; and hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant differences (p<0.05) among the four racial/ethnic groups: neutrophil, lymphocyte and eosinophil counts; and MCHC in males, and hemoglobin, MCV, MCH and MCHC in females. Conclusions Race/ethnicity-specific CBC RIs should be taken into consideration in a multiethnic population to better interpret patient status and make progress toward precision medicine.

scholarly journals Hematological parameters in Nile Tilápia, Oreochromis niloticus exposed to sub-letal concentrations of mercury

2007 ◽  
Vol 50 (4) ◽  
pp. 619-626 ◽  
Author(s):  
Nilton Massuo Ishikawa ◽  
Maria José Tavares Ranzani-Paiva ◽  
Julio Vicente Lombardi ◽  
Cláudia Maris Ferreira
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Oreochromis Niloticus ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Mean Corpuscular Hemoglobin ◽  
Blood Cell Count ◽  
Corpuscular Hemoglobin ◽  
Set Up

Mercury toxicity in tilapia, Oreochromis niloticus, (Linnaeus, 1758) was investigated by the hematological parameters after long-term (14 days) exposure to various Hg concentrations (0.02, 0.002, 0.0002mg/L Hg). Test groups were set up with three replicates for each concentration, plus the control group. Blood samples were collected from six individuals for each concentration at 0, 3, 7, 10 and 14 days of exposure. The hematological parameters analyzed were: total red blood cell count (RBC), hemoglobin concentration (Hb), hematocrit (Ht), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), total white blood cell count (WBC) and differential leukocyte counts and total thrombocyte count (Tr). There were no significant differences among the mean hematological values at the different Hg concentrations indicating that Hg at the concentrations studied was not toxic to tilapia.

scholarly journals Increasing running volume elicits hematological changes in trained endurance runners: a case study (El aumento del volumen de entrenamiento de carrera induce alteraciones hematológicas en corredores entrenados: un estudio de caso)

Retos ◽  
2018 ◽  
pp. 117-120
Author(s):  
José Augusto Rodrigues dos Santos
Keyword(s):  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Endurance Running ◽  
Mean Cell Volume ◽  
Endurance Runners ◽  
Hematological Indicators ◽  
Hematological Changes ◽  
Trained Runners

Abstract. Background: Endurance running training induces several hematological changes that increase the capture, transport and delivery of the oxygen to the exercising muscles. Objective: This study aimed to verify how a dramatic increase in running volume induced new alterations in several hematological indicators in previously trained endurance runners. Methods: Three subjects (PL: 26 years, 169,5 cm; HP, 27 years, 167,9 cm; MC, 27 years, 180,7 cm) running 10-12 km/day, increased their running volume to prepare the participation in a 100-km ultra-marathon. New training program included 10-12 training sessions per week, totalizing 200-260 km. Average daily running volume was 35.8±6.2 km. The parameters analyzed were: hemoglobin, erythrocytes, hematocrit, mean cell volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), leukocytes, neutrophils, eosinophils, lymphocytes, and monocytes.  Results: Erythrocyte count, hemoglobin, and hematocrit decreased 6.5%, 5.1% and 6.7%, respectively for the average of the three runners. Leukocytes, neutrophils, eosinophils, lymphocytes, and monocytes showed different alterations among participants with all the values remaining within normal reference values. Conclusion: Well-trained runners show further hematological alterations when training volume is dramatically increased, which can be seen as the specific adaptation to the new training level. It seems that hemogram is more sensitive than leucogram to the increase in running volume.Resumen. Antecedentes: El entrenamiento de resistencia aeróbica induce varios cambios hematológicos que aumentan la captura, el transporte y la entrega del oxígeno a los músculos en ejercicio. Objetivo: El objetivo de este estudio fue verificar cómo un aumento dramático en el volumen de corrida indujo nuevas alteraciones en varios indicadores hematológicos en corredores previamente entrenados. Métodos: Tres sujetos (PL: 26 años, 169,5 cm, HP, 27 años, 167,9 cm, MC, 27 años, 180,7 cm) corriendo 10-12 km / día, aumentaron su volumen de carrera para preparar la participación en un ultra maratón de 100 km. El nuevo programa de entrenamiento incluyó 10-12 sesiones de entrenamiento por semana, totalizando 200-260 km. El promedio diario de volumen de carrera fue de 35,8 ± 6,2 km. Los parámetros analizados fueron hemoglobina, eritrocitos, hematocrito, volumen celular medio (MCV), hemoglobina corpuscular media (MCH), concentración media de hemoglobina corpuscular (MCHC), leucocitos, neutrófilos, eosinofilos, linfocitos y monocitos. Resultados: El recuento de eritrocitos, la hemoglobina y el hematocrito disminuyeron 6,5%, 5,1% y 6,7%, respectivamente, para el promedio de los tres corredores. Los leucocitos, neutrófilos, eosinofilos, linfocitos y monocitos mostraron diferentes alteraciones entre los participantes con todos los valores restando dentro de los valores normales de referencia. Conclusión: Corredores bien entrenados muestran alteraciones hematológicas adicionales cuando el volumen de entrenamiento aumenta drásticamente, lo que puede ser visto como la adaptación específica al nuevo nivel de entrenamiento. Parece que el hemograma es más sensible que el leucograma al aumento en el volumen de entrenamiento de carrera.

scholarly journals Comparison of Hematological and Biochemical Profiles of Late Pregnant and Non-Pregnant Mares

2021 ◽  
Vol 22 (1) ◽  
pp. 1-7
Author(s):  
Murat Onur Yazlik ◽  
Ezgi Dikmeoglu ◽  
Arzu Esen ◽  
Ufuk Kaya ◽  
Özgenur Kafkas ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Biochemical Parameters ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Clinical Practices ◽  
Blood Cell Count ◽  
Corpuscular Hemoglobin ◽  
Mean Cell Volume ◽  
Pregnancy Status

The maternal body must adapt to fetal growth and development during the state of pregnancy for successful foal and mother. Pregnancy status as in other mammals is related to physiology and hematology. This study aimed to compare the hematology profiles and biochemical parameters of late pregnant and non-pregnant mares. Twenty-two mares were included in the study. Mares were divided into two groups according to the pregnancy status. Hematology profile and biochemical parameters were analyzed from blood samples collected from the jugular vein. All data were analyzed using Stata 12/MP4. White blood cell count, lymphocyte, red blood cell count, hemoglobin concentration, hematocrit, monocyte and percentage of monocyte were significantly lower in non-pregnant mares compared to late pregnant mares (P<0.05). No significant differences were noted in values of neutrophil, eosinophil, mean cell volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, platelet, mean platelet volume, red cell distribution width in both groups (P>0.05). On the other hand, biochemical parameters analysis showed that calcium, total bilirubin, and triglyceride concentrations were greater in late pregnant mares (P<0.05). However, urea, albumin, cholesterol, and magnesium concentrations were similar among groups (P>0.05). In conclusion, the present study showed hematology profile and biochemical parameters differences in late pregnant and non-pregnant mares. These values could be useful in clinical practices to assess the situation of late pregnant mares.

scholarly journals Complete Blood Count Peculiarities in Pregnant SARS-CoV-2-Infected Patients at Term: A Cohort Study

Diagnostics ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 80
Author(s):  
Roxana Covali ◽  
Demetra Socolov ◽  
Razvan Socolov ◽  
Ioana Pavaleanu ◽  
Alexandru Carauleanu ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Blood Cell Count ◽  
Corpuscular Hemoglobin ◽  
Distribution Width

Background: During viral outbreaks, pregnancy poses an increased risk of infection for women. Methods: In a prospective study, all patients admitted for delivery at term to Elena Doamna Obstetrics and Gynecology University Hospital in Iasi, Romania, between 1 April 2020 and 31 December 2020 were included. There were 457 patients, divided into two groups: group 1, SARS-CoV-2-positive patients (n = 46) and group 2, SARS-CoV-2-negative patients (n = 411). Among other tests, complete blood count was determined upon admittance, and the following values were studied: white blood cell count, lymphocytes, neutrophils, red blood cell count, hemoglobin, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, mean corpuscular volume, red blood cell distribution width, hematocrit, platelet count, mean platelet volume, platelet distribution width, plateletcrit, and platelet large cell ratio. Results: in pregnant SARS-CoV-2-infected patients at term, there was a significant decrease in white blood cell, neutrophil, and lymphocyte count, and an increase in mean corpuscular hemoglobin concentration, compared to healthy pregnant women at term, although all still within normal limits. None of the other components of the complete blood count or fetal outcomes studied was significantly influenced by SARS-CoV-2 infection in pregnant patients at term.

scholarly journals Effects of ammonia toxicity on growth performance, cortisol, glucose and hematological response of Nile Tilapia (Oreochromis niloticus)

2016 ◽  
Vol 1 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Moustafa M. Zeitoun ◽  
Kheir El-Din M. EL-Azrak ◽  
Mohamed A. Zaki ◽  
Bahig R. Nemat-Allah ◽  
El-Sayed E. Mehana
Keyword(s):  
Growth Rate ◽  
Growth Performance ◽  
Ammonium Chloride ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Fish Production ◽  
Corpuscular Hemoglobin ◽  
Male And Female ◽  
Males And Females

Ammonia is a production limiting factor in the aquaculture media affecting fish production. A study was designed to scrutinize effects of ammonia on growth performance, survival, cortisol and hematological parameters of Tilapia fish. The study examined effects of 96 h-incubation of male and female Tilapia with 3 mg ammonium chloride per a liter of water compared to control. The study has been carried out in the physiology laboratory of the department of animal and fish production, Alexandria University. Fourteen aquaria were used (6 control and 8 ammoniated). Each aquarium contained 6 fish (half the population males and the other have females). Duration of the control reared fish was 30 days, however the duration for ammoniated group was 4 days. In all stressed fish, there found decreases in final body weight, average daily gain and specific growth rate as compared to controls. Hematological parameters revealed increases (P0.05) in total leukocyte counts in both males and females exposed to stressors. There were significant decreases (P0.05) in red blood cell, hematocrit value and hemoglobin concentration in both males and females. There were non-significant differences (P0.10) in these parameters between males and females. Exposing both male and female tilapia to ammonia, resulted in increases (P0.05) in mean corpuscular volume (MCV). Mean corpuscular hemoglobin (MCH) didn’t change in male tilapia, while females expressed increased MCH values in the ammonia condition. Mean corpuscular hemoglobin concentration (MCHC) decreased (P0.05) under ammonia with no differences between males and females. Differential leukocyte count exhibited increases (P0.05) in neutrophils in ammonia-exposed males and females and decreases (P0.05) in eosinophils and monocytes in males, but not in females. However, lymphocytes decreased (P0.05) in both females and males exposed to ammonia. Cortisol level increased (P0.05) by about 2 folds in both sexes of fish exposed to ammonia (2.95 and 2.72 vs6.40 and 6.48 ng/ml in control males and females vs ammonia-exposed males and females).Rearing tilapia fish in media containing high level (3mg/l water) of ammonium chloride not only deteriorated growth rate but it also negatively affected the health wellbeing. 

scholarly journals Evaluation of the automated hematology analyzer Sysmex XT-2000iV™ compared to the ADVIA® 2120 for its use in dogs, cats, and horses

2011 ◽  
Vol 23 (6) ◽  
pp. 1168-1180 ◽  
Author(s):  
Natali Bauer ◽  
Julia Nakagawa ◽  
Cathrin Dunker ◽  
Klaus Failing ◽  
Andreas Moritz
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Rank Correlation ◽  
Correlation Coefficients ◽  
Reference Method ◽  
Hemoglobin Concentration ◽  
Differential Count ◽  
Mean Corpuscular Hemoglobin ◽  
Blood Cell Count ◽  
Hematology Analyzer

The automated laser-based hematology analyzer Sysmex XT-2000 iV™ providing a complete blood cell count (CBC) and 5-part differential has been introduced in large veterinary laboratories. The aim of the current study was to determine precision, linearity, and accuracy of the Sysmex analyzer. Reference method for the accuracy study was the laser-based hematology analyzer ADVIA® 2120. For evaluation of accuracy, consecutive fresh blood samples from healthy and diseased cats ( n = 216), dogs ( n = 314), and horses ( n = 174) were included. A low intra-assay coefficient of variation (CV) of approximately 1% was seen for the CBC except platelet count (PLT). An intra-assay CV ranging between 2% and 5.5% was evident for the differential count except for feline and equine monocytes (7.7%) and horse eosinophils (15.7%). Linearity was excellent for white blood cell count (WBC), hematocrit value, red blood cell count (RBC), and PLT. For all evaluated species, agreement was excellent for WBC and RBC, with Spearman rank correlation coefficients (rs) ranging from >0.99 to 0.98. Hematocrit value correlated excellently in cats and dogs, whereas for horses, a good correlation was evident. A good correlation between both analyzers was seen in feline and equine PLT (rs = 0.89 and 0.92, respectively), whereas correlation was excellent for dogs (rs = 0.93). Biases were close to 0 except for mean corpuscular hemoglobin concentration (4.11 to −7.25 mmol/l) and canine PLT (57 × 109/l). Overall, the performance of the Sysmex analyzer was excellent and compared favorably with the ADVIA analyzer.

scholarly journals CALIPER Hematology Reference Standards (II)

2020 ◽  
Vol 154 (3) ◽  
pp. 342-352 ◽  
Author(s):  
Victoria Higgins ◽  
Houman Tahmasebi ◽  
Mary Kathryn Bohn ◽  
Alexandra Hall ◽  
Khosrow Adeli
Keyword(s):  
Children And Adolescents ◽  
Hemoglobin Concentration ◽  
Reference Intervals ◽  
Reference Standards ◽  
Reference Database ◽  
Specific Reference ◽  
Mean Corpuscular Hemoglobin ◽  
Healthy Children ◽  
Cell Percentage ◽  
Age And Sex

Abstract Objectives The objective of this study was to establish comprehensive age- and sex-specific reference intervals for hematologic parameters in the CALIPER cohort of healthy children and adolescents. Methods A total of 536 healthy children and adolescents (birth to 21 years) were recruited with informed consent, and whole blood samples were analyzed for 27 hematologic parameters on the Beckman Coulter DxH 520 system. Age- and sex-specific pediatric reference standards were established. Reference values obtained on the DxH 520 were also compared with data obtained on a larger laboratory-based instrument (DxH 900). Results Most hematologic parameters showed significant age- and/or sex-specific changes during growth and development. Of the 27 hematologic parameters, all except four (mean corpuscular hemoglobin concentration, basophil percentage, low hemoglobin density, immature cell percentage) required age partitioning, and eight required sex partitioning. Conclusions This study establishes a robust pediatric hematology reference database that will assist in more accurate test result interpretation. Our data clearly demonstrate significant variation in hematologic parameter concentrations in children and adolescents, necessitating the use of pediatric-specific reference standards.

scholarly journals Blood parameter analysis and morphological alterations as biomarkers on the health of Hoplias malabaricus and Geophagus brasiliensis

2006 ◽  
Vol 49 (3) ◽  
pp. 441-448 ◽  
Author(s):  
Silvia Romão ◽  
Lucélia Donatti ◽  
Matheus O. Freitas ◽  
Josiane Teixeira ◽  
Josiana Kusma
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Hemoglobin Concentration ◽  
Parameter Analysis ◽  
Mean Corpuscular Hemoglobin ◽  
Blood Parameter ◽  
Blood Cell Count ◽  
Hoplias Malabaricus ◽  
Morphological Alterations ◽  
Geophagus Brasiliensis

This study aimed to assess the influence of the environment on fish health. Samples of Hoplias malabaricus and Geophagus brasiliensis, were collected from three different environments: area I was urban and areas II and III were rural. Analyses of red blood cell count, microhematocrit, hemoglobin concentration, white blood cell count and differential white cell count in blood smear were carried out. Mean corpuscular volume and mean corpuscular hemoglobin concentration were calculated. To analyze morphological alterations, gills, liver, kidney and gonads were submitted to routine histological processing. Individuals collected from area III had slightly lower blood indices than collected from area I . Severe kidney changes, degeneration of and crystallization within kidney tubules were observed. In area I, crystallization was observed in 92% of the specimens of G. brasiliensis. These results suggested that such alterations were related with poor water circulation in the place.

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