scholarly journals Serum Zinc and Selenium Concentrations in Patients with Hypertrophy and Remodelling of the Left Ventricle Secondary to Arterial Hypertension

Antioxidants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1803
Author(s):  
Paweł Gać ◽  
Karolina Czerwińska ◽  
Małgorzata Poręba ◽  
Adam Prokopowicz ◽  
Helena Martynowicz ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Ventricular Hypertrophy ◽  
Serum Zinc ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Serum Selenium ◽  
Hypertensive Patients ◽  
Concentric Hypertrophy

The aim of the study was to assess the relationship between serum selenium and zinc concentrations (Se-S and Zn-S) and the left ventricle geometry in patients suffering from arterial hypertension. A total of 78 people with arterial hypertension (mean age: 53.72 ± 12.74 years) participated in the study. Se-S and Zn-S were determined in all patients. The type of left ventricular remodelling and hypertrophy was determined by the left ventricular mass index (LVMI) and relative wall thickness (RWT) measured by echocardiography. Se-S and Zn-S in the whole group were 89.84 ± 18.75 µg/L and 0.86 ± 0.13 mg/L. Normal left ventricular geometry was found in 28.2% of patients; left ventricular hypertrophy (LVH) in 71.8%, including concentric remodelling in 28.2%, concentric hypertrophy in 29.5%, and eccentric hypertrophy in 14.1%. LVH was statistically significantly more frequent in patients with Se-S < median compared to patients with Se-S ≥ median (87.2% vs. 56.4%, p < 0.05), as well as in patients with Zn-S < median compared to patients with Zn-S ≥ median (83.8% vs. 60.9%, p < 0.05). In hypertensive patients, older age, higher LDL cholesterol, higher fasting glucose, lower Se-S, and lower Zn-S were independently associated with LVH. In conclusion, in hypertensive patients, left ventricular hypertrophy may be associated with low levels of selenium and zinc in the serum.

scholarly journals Sostoyanie serdtsa po dannym ekhokardiografiiu lits s ozhireniem, manifestirovavshimv pubertatnyy period

2011 ◽  
Vol 8 (3) ◽  
pp. 38-45 ◽  
Author(s):  
E V Mitroshina
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Similar Frequency ◽  
Ventricular Geometry ◽  
Concentric Hypertrophy ◽  
Puberty Onset

47 male patients were included in this study: the group of 17 adolescents with puberty-onset obesity (aged 19,7±0,37 years), the group of 20 adults with puberty-onset obesity (aged 32,25±0,96 years), 10 gender-matched controls (aged 20,8±0,25 years). All subjects underwent echocardiographic and lipid profile examination. Conclusion: Among adolescent males with puberty-onset obesity normal left ventricular geometry was encountered with similar frequency in both subgroups, with and without arterial hypertension. When left ventricular hypertrophy develops, it may be presented as either concentric or eccentric hypertrophy. In men with puberty-onset obesity the of patients, duration of their disease and concomitant arterial hypertension aggravate left ventricular hypertrophy. In men with puberty- onset obesity and arterial hypertension the most common pattern of impaired left ventricular geometry is concentric hypertrophy. Regardless of the presence of arterial hypertension, men with puberty-onset obesity have a tendency to development of left ventricular diastolic dysfunction that may be combined with both concentric and eccentric left ventricular hypertrophy.

scholarly journals Left ventricular hypertrophy in patients treated with regular hemodialyses

2008 ◽  
Vol 61 (7-8) ◽  
pp. 369-374 ◽  
Author(s):  
Dejan Petrovic ◽  
Biljana Stojimirovic
Keyword(s):  
Risk Factors ◽  
Left Ventricle ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Pressure Overload ◽  
Left Ventricular ◽  
Cardiovascular Morbidity ◽  
Morbidity And Mortality ◽  
Concentric Hypertrophy ◽  
Cardiovascular Morbidity And Mortality

Left ventricular hypertrophy is the main risk factor for development of cardiovascular morbidity and mortality in patients on hemodialysis. Left ventricular hypertrophy is found in 75% of the patients treated with hemodialysis. Risk factors for left ventricular hypertrophy in patients on hemodialysis include: blood flow through arterial-venous fistula, anemia, hypertension, increased extracellular fluid volume, oxidative stress, microinflammation, hyperhomocysteinemia, secondary hyperpara- thyroidism, and disturbed calcium and phosphate homeostasis. Left ventricular pressure overload leads to parallel placement of new sarcomeres and development of concentric hypertrophy of left ventricle. Left ventricular hypertrophy advances in two stages. In the stage of adaptation, left ventricular hypertrophy occurs as a response to increased tension stress of the left ventricular wall and its action is protective. When volume and pressure overload the left ventricle chronically and without control, adaptive hypertrophy becomes maladaptive hypertrophy of the left ventricle, where myocytes are lost, systolic function is deranged and heart insufficiency is developed. Left ventricular mass index-LVMi greater than 131 g/m2 in men and greater than 100 g/m2 in women, and relative wall thickness of the left ventricle above 0.45 indicate concentric hypertrophy of the left ventricle. Eccentric hypertrophy of the left ventricle is defined echocardiographically as LVMi above 131 g/m2 in men and greater than 100 g/m2 in women, with RWT ?0.45. Identification of patients with increased risk for development of left ventricular hypertrophy and application of appropriate therapy to attain target values of risk factors lead to regression of left ventricular hypertrophy, reduced cardiovascular morbidity and mortality rates and improved quality of life in patients treated with regular hemodialyses.

scholarly journals Comparison of efficacy of fixed combinations of verapamil SR+ trandolapril and captopril + HCTZ in high risk hypertensive patients

2007 ◽  
Vol 13 (2) ◽  
pp. 141-144
Author(s):  
S. V. Nedogoda ◽  
Т. A. Chalabi ◽  
V. V. Tsoma ◽  
U. A. Brel
Keyword(s):  
Blood Pressure ◽  
High Risk ◽  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Glucose Level ◽  
Ventricular Hypertrophy ◽  
Randomized Study ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Vascular Elasticity

The blinded randomized study the clinical effecacy and tolerability during 6 month therapy with one of two fixed combinations Tarka (verapamil SR+trandolapril) and Capozide (captopril+HCTZ) were compared patients (20 patients at every group) with arterial hypertension who did not achiev target blood pressure on monotherapy. Tarka was more effective decreased of left ventricular hypertrophy and improved vascular elasticity. Tarka also had better T/P coefficient. Tarka improved glucose level, Capozide worsen potassium levels.

scholarly journals Gender differences of voltage electrocardiographic criteria of left ventricular hypertrophy in hypertensive individuals living in the North

2012 ◽  
Vol 18 (2) ◽  
pp. 148-152
Author(s):  
E. A. Makoveeva ◽  
L. P. Efimova
Keyword(s):  
Gender Differences ◽  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
The North ◽  
Design And Methods

Objective. To estimate the changes of voltage electrocardiographic criteria of the left ventricular hypertrophy in arterial hypertension in subjects of different gender. Design and methods. The study included 94 hypertensive patients (55 males, 39 females). Mean age was 51 ± 6 years. Based on gender and the presence of left ventricular hypertrophy patients were divided into four groups. Results. There were significant differences of indices of Sokolow-Lyon and Cornell in males with I and II stages of arterial hypertension (р = 0,012 and р = 0,017, respectively). The same differences were found in females with I and II stages of arterial hypertension (р = 0,037 and р = 0,001, respectively). Specificity was 92 % for both indices, and the sensitivity was 26 % for Sokolow-Lyon index, and 39 % for Cornell index. In women sensitivity was 0 and 72 % for Sokolow-Lyon and Cornell indices, respectively, and specificity was more than 90 % for both criteria. Conclusion. Gender differences should be considered when voltage electrocardiographic criteria of the left ventricular hypertrophy are assessed in hypertensive patients.

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