scholarly journals Dietary Vitamin C and Vitamin C Derived from Vegetables Are Inversely Associated with the Risk of Depressive Symptoms among the General Population

Antioxidants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1984
Author(s):  
Anni Wang ◽  
Jia Luo ◽  
Tianhao Zhang ◽  
Dongfeng Zhang
Keyword(s):  
Depressive Symptoms ◽  
General Population ◽  
Vitamin C ◽  
Population Data ◽  
Water Soluble ◽  
Dietary Vitamin ◽  
Response Analysis ◽  
Health And Nutrition ◽  
Daily Diet ◽  
Patient Health

Vitamin C is a water-soluble antioxidant. Reducing the level of oxidative stress can alleviate depression. Therefore, we investigated the correlation between dietary vitamin C intake and the risk of depressive symptoms in the general population. Data from the 2007–2018 National Health and Nutrition Examination Survey were used in our study. The dietary intake of vitamin C was assessed by two 24-h dietary recalls. Depressive symptoms were assessed with the Patient Health Questionnaire-9. Logistic regression and restricted cubic spline models were applied to assess the relationship between dietary vitamin C intake and the risk of depressive symptoms. The multivariate adjusted odds ratio (95% confidence interval) of depressive symptoms for the highest vs. lowest category of dietary vitamin C intake and vitamin C intake derived from vegetables were 0.73 (0.58–0.91) and 0.73 (0.56–0.95). In subgroup analyses, dietary vitamin C intake was negatively correlated with the risk of depressive symptoms in females 18–39 years old and 40–59 year-old groups. A dose-response analysis showed that there was a nonlinear relationship between dietary vitamin C intake and the risk of depressive symptoms. Dietary vitamin C intake and vitamin C intake derived from vegetables were inversely associated with the risk of depressive symptoms among the general population. We recommend increasing the intake of vegetables in daily diet.

scholarly journals P547 Inadequate vitamin C status and association with inflammatory biomarkers in adults with active Crohn’s disease

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S465-S466
Author(s):  
C Wall ◽  
K MacFarlane ◽  
A Carr ◽  
A Day ◽  
R Gearry
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Vitamin C ◽  
High Performance ◽  
Serum Vitamin ◽  
Water Soluble ◽  
Dietary Vitamin ◽  
Micronutrient Deficiencies ◽  
Faecal Calprotectin ◽  
Exclusive Enteral Nutrition

Abstract Background Micronutrient deficiencies are common in inflammatory bowel disease (IBD) due to the inflammatory burden and changes in dietary intake. Vitamin C, an essential water-soluble antioxidant required for tissue repair and immune function, is found primarily in fresh fruit and vegetables however, this food group is more often avoided by people with IBD compared with the general population. This research aimed to determine serum vitamin C status in subjects with active Crohn’s disease, measure urinary vitamin C excretion in healthy controls (HC) and Crohn’s disease patients before and after exclusive enteral nutrition (EEN) and assess associations between inflammatory markers and vitamin C. Methods Stored serum and random urine samples prospectively collected from adults with mild to moderately active Crohn’s disease and adult HC were analysed. Both HC and Crohn’s disease groups received EEN with a known vitamin C content for two weeks. Serum and urinary vitamin C were measured using high-performance liquid chromatography with electrochemical detection. Urinary vitamin C was standardised to urinary creatinine. Non-parametric t-tests and correlations were performed. Results EEN was initiated in 38 patients (aged 16 to 39 years old). Inadequate serum vitamin C (<50 µmol/l) was present in 36/38 patients with active Crohn’s disease and 45% had hypovitaminosis C. Baseline C-reactive protein (CRP) was 12 mg/l (range, 3 to 158 mg/l) and faecal calprotectin was 1065 µg/g (range, 60 to 3838 µg/g). Serum vitamin C correlated weakly with CRP (r = −0.30 95% CI: −0.58 to 0.03, p = 0.06) but not with faecal calprotectin. Two weeks of EEN was completed by 30 (79%) patients and 17 (81%) HC. The average vitamin C intake was 168mg/day (range, 108–252 mg/day). Baseline urinary excretion of vitamin C was low in both Crohn’s disease and HC. Following EEN urinary vitamin C excretion increased significantly in both groups (Figure 1). Conclusion Patients with active Crohn’s disease had inadequate vitamin C status. EEN increased urinary vitamin C excretion in both Crohn’s disease and HC, suggesting low baseline dietary vitamin C intake and potentially enhanced utilisation. Further research with a larger patient cohort would provide a greater understanding of vitamin C metabolism in active Crohn’s disease.

scholarly journals Dietary vitamin C intake protects against COPD: the Korea National Health and Nutrition Examination Survey in 2012

2016 ◽  
Vol Volume 11 ◽  
pp. 2721-2728 ◽  
Author(s):  
Hye Jung Park ◽  
Min Kwang Byun ◽  
Hyung Jung Kim ◽  
Jae Yeol Kim ◽  
Yu Il Kim ◽  
...  
Keyword(s):  
Vitamin C ◽  
National Health ◽  
Dietary Vitamin ◽  
Nutrition Examination Survey ◽  
Health And Nutrition

scholarly journals The association between handgrip strength and depression in cancer survivors: a cross-section study

2021 ◽  
Author(s):  
Xiao-Ming Zhang ◽  
Zhi-Biao Zhang ◽  
Wei Chen ◽  
Xinjuan Wu
Keyword(s):  
Depressive Symptoms ◽  
Cancer Survivors ◽  
National Health ◽  
Handgrip Strength ◽  
Final Analysis ◽  
Nutrition Examination Survey ◽  
Logistic Regression Models ◽  
Health And Nutrition ◽  
Public Data ◽  
Patient Health

Abstract BackgroundThe association between handgrip strength and depression in cancer survivors was unknown. We aim to examine the associations of handgrip strength and depression in cancer survivors by using public data (National Health and Nutrition Examination Survey). MethodsWe combined two waves of the data of the National Health and Nutrition Examination Survey during 2011-2014 to explore this important issue. The variable of handgrip strength was extracted by the maximum value of each hand. The depressive symptom was assessed by the Patient Health Questionnaire (PHQ-9) with the cut-off >=10 points indicating depressive symptoms. Other characteristics and health-related variables were evaluated. Multivariable logistic regression models were adopted to explore the associations between handgrip strength or low handgrip strength and depressive symptoms by adjusting for potential confounding factors. ResultsThere were 992 cancer survivors in our final analysis, with 456 (45.97%) male and the mean (SD) age of this whole group being 64.75 (14.02) years. The prevalence of low handgrip strength and depression was 20.36% and 13.31%, respectively. The results showed that handgrip strength was negatively associated with depression (OR=0.97,95%CI:0.96-0.99; P=0.01). In addition, after adjusting age, race, education, marital status, sleep disorder, history of stroke, polypharmacy and BMI, cancer survivors with low handgrip strength had a 2.11-fold risk of depression, compared to those with normal handgrip strength (OR=2.11,95%CI:1.19-3.73; P=0.01). ConclusionsLow handgrip strength, simple and modifiable parameter, is associated with a higher risk of depression in cancer survivors. Prospective cohort studies are warranted to confirm this association in the future.

scholarly journals Household pesticide exposure and depression syndromes: evidence from NHANES, 2005-2014

2020 ◽  
Author(s):  
Haiyan Chen ◽  
Guang Hao
Keyword(s):  
General Population ◽  
Pesticide Exposure ◽  
Control Group ◽  
Depression Symptoms ◽  
Health And Nutrition ◽  
Adult Participants ◽  
Prevalence Of Depression ◽  
Patient Health ◽  
First Time

Abstract Background The effect of household pesticide exposure on depression symptoms in general population is underexplored, and the role of exercise in the association between pesticide exposure and depression symptoms is unclear. The goals of this study are to examine whether the association of household pesticide exposure and depression symptoms exist in general population, and, if so, whether exercise can attenuate the effect of household pesticide on depression symptoms.Methods We used data from the 2005-2014 NHANES (National Health and Nutrition Examination Surveys), including a total of 14 708 US adult participants ≥ 20 years old. Depression symptoms was assessed using the Patient Health Questionnaire (PHQ-9).Results The prevalence of depression symptoms was significantly higher in participants who exposed to household pesticide compared to those not (28.9% vs. 21.1%, P <0.001). Household pesticide exposure was significantly associated with risk of depression symptoms. A significant interaction between exercise and pesticide exposure on depression symptoms was observed ( P =0.038). The prevalence of depression symptoms was significantly higher in pesticide exposure group compared to the control group (35.0% vs. 24.9%, P <0.001) in the population with light physical activity. However, we did not find a significant association in the group with moderate + vigorous physical activity.Conclusion This study further confirmed that household pesticide exposure is associated with a high risk of depression symptoms in the general population. More importantly, we for the first time reported that exercise tends to attenuate the effect of household pesticide exposure on depression symptoms.

scholarly journals Association between tinnitus and depressive symptoms in the South Korean population

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261257
Author(s):  
Minah Park ◽  
Soo Hyun Kang ◽  
Fatima Nari ◽  
Eun-Cheol Park ◽  
Sung-In Jang
Keyword(s):  
Depressive Symptoms ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Korean Population ◽  
Multiple Logistic Regression ◽  
Health Questionnaire ◽  
Middle Aged ◽  
South Korean ◽  
Health And Nutrition ◽  
Patient Health

In this study, we aimed to examine the association between tinnitus and depressive symptoms in middle-aged and elderly South Korean population. The participants were selected from among those who participated in the 2014, 2016, and 2018 Korea National Health and Nutrition Examination Surveys. The incidence and severity of tinnitus was assessed using a self-reported questionnaire, while depressive symptoms were evaluated using self-reported Patient Health Questionnaire-9. Multiple logistic regression was performed to examine the association between tinnitus and depressive symptoms. Overall, 10 979 (4821 men and 6158 women) participants were enrolled in the study. Regardless of sex, individuals who reported having tinnitus were more likely to have depressive symptoms than those without tinnitus (men: odds ratio 1.53, 95% confidence interval 1.01–2.32; women: odds ratio 1.78, 95% confidence interval 1.35–2.35). In severe cases of tinnitus, women were more likely to have depressive symptoms (odds ratio 7.18, 95% confidence interval 3.71–13.87) compared to men. This study revealed a significant association between tinnitus and depressive symptoms among the middle-aged and elderly South Korean population.

scholarly journals Exposure to neonicotinoid insecticides in the U.S. general population: Data from the 2015–2016 national health and nutrition examination survey

2019 ◽  
Vol 176 ◽  
pp. 108555 ◽  
Author(s):  
Maria Ospina ◽  
Lee-Yang Wong ◽  
Samuel E. Baker ◽  
Amanda Bishop Serafim ◽  
Pilar Morales-Agudelo ◽  
...  
Keyword(s):  
General Population ◽  
National Health ◽  
Population Data ◽  
Nutrition Examination Survey ◽  
Neonicotinoid Insecticides ◽  
Health And Nutrition ◽  
The U.S

Vitamin D supplements reduce depressive symptoms and cardiac events in heart failure patients with moderate to severe depressive symptoms

2017 ◽  
Vol 17 (3) ◽  
pp. 207-216 ◽  
Author(s):  
Eun Kyeung Song ◽  
Jia-Rong Wu ◽  
Debra K Moser ◽  
Seok-Min Kang ◽  
Terry A Lennie
Keyword(s):  
Heart Failure ◽  
Vitamin D ◽  
Depressive Symptoms ◽  
Vitamin D Deficiency ◽  
Dietary Vitamin ◽  
Cardiac Events ◽  
Heart Failure Patients ◽  
Patient Health ◽  
Vitamin D Supplements ◽  
Dietary Vitamin D

Background: Depressive symptoms and vitamin D deficiency predict cardiac events in heart failure patients, but whether vitamin D supplements are associated with depressive symptoms and cardiac events in heart failure patients remains unknown. Purpose: The purpose of this study was to compare the association of vitamin D supplement use with depressive symptoms and cardiac events in heart failure patients with mild or moderate to severe depressive symptoms. Methods: A total of 177 heart failure patients with depressive symptoms (Patient Health Questionnaire-9 score ≥5) completed a three-day food diary to determine dietary vitamin D deficiency. Patients were split into four groups by dietary vitamin D adequacy versus deficiency and vitamin D supplement use versus non-use. The Patient Health Questionnaire-9 was used to reassess depressive symptoms at six months. Data on cardiac events for up to one year and vitamin D supplement use were obtained from patient interview and medical record review. Hierarchical linear and Cox regressions were used for data analysis. Results: Sixty-six patients (37.3%) had dietary vitamin D deficiency and 80 (45.2%) used vitamin D supplements. In patients with moderate to severe depressive symptoms, the group with dietary vitamin D deficiency and no supplements had the highest Patient Health Questionnaire-9 score at six months (β=0.542, p<0.001) and shortest cardiac event-free survival ( p<0.001) among the four groups, the group with dietary vitamin D deficiency and no supplements didn’t have the highest Patient Health Questionnaire-9 score at six months and shortest cardiac event-free survival in patients with mild depressive symptoms. Conclusions: Vitamin D supplements predicted lower depressive symptoms and reduced cardiac events for patients with moderate to severe depressive symptoms. Vitamin D deficiency was associated with higher risk of shorter cardiac event-free survival in heart failure patients regardless of vitamin D supplementation.

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