scholarly journals Electroanalysis of Fentanyl and Its New Analogs: A Review

Biosensors ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 26
Author(s):  
Marta Katarzyna Choińska ◽  
Ivana Šestáková ◽  
Vojtěch Hrdlička ◽  
Jana Skopalová ◽  
Jan Langmaier ◽  
...  

The review describes fentanyl and its analogs as new synthetic opioids and the possibilities of their identification and determination using electrochemical methods (e.g., voltammetry, potentiometry, electrochemiluminescence) and electrochemical methods combined with various separation methods. The review also covers the analysis of new synthetic opioids, their parent compounds, and corresponding metabolites in body fluids, such as urine, blood, serum, and plasma, necessary for a fast and accurate diagnosis of intoxication. Identifying and quantifying these addictive and illicit substances and their metabolites is necessary for clinical, toxicological, and forensic purposes. As a reaction to the growing number of new synthetic opioid intoxications and increasing fatalities observed over the past ten years, we provide thorough background for developing new biosensors, screen-printed electrodes, or other point-of-care devices.

PLoS ONE ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. e0196656 ◽  
Author(s):  
Rui S. Gomes ◽  
Felismina T. C. Moreira ◽  
Ruben Fernandes ◽  
M. Goreti F. Sales

Biosensors ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 32 ◽  
Author(s):  
Beatriz Pérez-Fernández ◽  
Agustín Costa-García ◽  
Alfredo de la Escosura- Muñiz

Pesticides are among the most important contaminants in food, leading to important global health problems. While conventional techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) have traditionally been utilized for the detection of such food contaminants, they are relatively expensive, time-consuming and labor intensive, limiting their use for point-of-care (POC) applications. Electrochemical (bio)sensors are emerging devices meeting such expectations, since they represent reliable, simple, cheap, portable, selective and easy to use analytical tools that can be used outside the laboratories by non-specialized personnel. Screen-printed electrodes (SPEs) stand out from the variety of transducers used in electrochemical (bio)sensing because of their small size, high integration, low cost and ability to measure in few microliters of sample. In this context, in this review article, we summarize and discuss about the use of SPEs as analytical tools in the development of (bio)sensors for pesticides of interest for food control. Finally, aspects related to the analytical performance of the developed (bio)sensors together with prospects for future improvements are discussed.


The Analyst ◽  
2015 ◽  
Vol 140 (17) ◽  
pp. 6071-6078 ◽  
Author(s):  
Thangamuthu Madasamy ◽  
Christian Santschi ◽  
Olivier J. F. Martin

Electrochemical point-of-care analysis of homocysteine in a drop of the blood plasma samples.


2013 ◽  
Vol 182 ◽  
pp. 733-740 ◽  
Author(s):  
Felismina T.C. Moreira ◽  
Rosa A.F. Dutra ◽  
João P.C. Noronha ◽  
João C.S. Fernandes ◽  
M. Goreti F. Sales

Diagnostics ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 517 ◽  
Author(s):  
Nicolae-Bogdan Mincu ◽  
Veronica Lazar ◽  
Dana Stan ◽  
Carmen Marinela Mihailescu ◽  
Rodica Iosub ◽  
...  

Due to rapidly spreading infectious diseases and the high incidence of other diseases such as cancer or metabolic syndrome, there is a continuous need for the development of rapid and accurate diagnosis methods. Screen-printed electrodes-based biosensors have been reported to offer reliable results, with high sensitivity and selectivity and, in some cases, low detection limits. There are a series of materials (carbon, gold, platinum, etc.) used for the manufacturing of working electrodes. Each version comes with advantages, as well as challenges for their functionalization. Thus, the aim is to review the most promising biosensors developed using screen-printed electrodes for the detection/quantification of proteins, biomarkers, or pathogenic microorganisms.


Author(s):  
Minhaz Uddin Ahmed ◽  
Mohammad Mosharraf Hossain ◽  
Mohammadali Safavieh ◽  
Yen Lu Wong ◽  
Ibrahim Abd Rahman ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Enock Matovu ◽  
Anne Juliet Kazibwe ◽  
Claire Mack Mugasa ◽  
Joseph Mathu Ndungu ◽  
Zablon Kithingi Njiru

Human African trypanosomiasis is a debilitating disease prevalent in rural sub-Saharan Africa. Control of this disease almost exclusively relies on chemotherapy that should be driven by accurate diagnosis, given the unacceptable toxicity of the few available drugs. Unfortunately, the available diagnostics are characterised by low sensitivities due to the inherent low parasitaemia in natural infections. Demonstration of the trypanosomes in body fluids, which is a prerequisite before treatment, often follows complex algorithms. In this paper, we review the available diagnostics and explore recent advances towards development of novel point-of-care diagnostic tests.


Proceedings ◽  
2017 ◽  
Vol 1 (8) ◽  
pp. 842 ◽  
Author(s):  
Davide Migliorelli ◽  
Silvia Generelli ◽  
Nicolas Glaser ◽  
Mirta Viviani ◽  
Lea Mühlebach ◽  
...  

Author(s):  
M. G. Williams ◽  
C. Corn ◽  
R. F. Dodson ◽  
G. A. Hurst

During this century, interest in the particulate content of the organs and body fluids of those individuals affected by pneumoconiosis, cancer, or other diseases of unknown etiology developed and concern was further prompted with the increasing realization that various foreign particles were associated with or caused disease. Concurrently particularly in the past two decades, a number of methods were devised for isolating particulates from tissue. These methods were recently reviewed by Vallyathan et al. who concluded sodium hypochlorite digestion was both simple and superior to other digestion procedures.


2011 ◽  
Vol 56 (11) ◽  
pp. 3988-3995 ◽  
Author(s):  
Elena Jubete ◽  
Kamila Żelechowska ◽  
Oscar A. Loaiza ◽  
Pedro J. Lamas ◽  
Estibalitz Ochoteco ◽  
...  

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