CONTROL SYSTEM FOR NEEDLE INSERTION INTO THE PERIPHERAL VENOUS VESSEL

2021 ◽  
pp. 122-125
Author(s):  
Екатерина Александровна Витоженц ◽  
Александр Викторович Кобелев
Keyword(s):  
Experimental Studies ◽  
Needle Insertion ◽  
Tissue Type ◽  
Mixed System ◽  
Injection Needle ◽  
Recorded Signal ◽  
Venous Puncture ◽  
Complex Design ◽  
The Moment ◽  
Venous Vessel

Предложен новый способ контроля введения инъекционной иглы в просвет вены на основе измерений электрического импеданса с помощью смешанной системы электродов, состоящей из биполярного и тетраполярного звеньев. Исследованы альтернативные схемы расположения электродов при проведении контроля венозной пункции биоимпедансным методом - они имеют более сложную конструкцию, используют дорогостоящие специализированные коаксиальные иглы, не позволяют однозначно определить факт прокола стенки венозного сосуда, нуждаются в дополнительной фильтрации регистрируемого сигнала с целью корректной интерпретации результата. Эффективность предложенной методики проверялась в ходе экспериментальных исследований на 5 добровольцах. Результаты экспериментов позволили идентифицировать 4 стадии нахождения инъекционной иглы относительно верхней конечности: нет касания, касание кожного покрова, нахождение под кожей коже, попадание в просвет вены. Идентификация положений инъекционной иглы происходит в реальном времени без дополнительной фильтрации регистрируемого сигнала. Метод позволяет обнаружить момент прокола стенки венозного сосуда стандартной инъекционной иглой, что в дальнейшем позволит сэкономить на изготовлении специализированных многослойных игольчатых электродов и внедрить данный способ контроля за проведением венепункции в медицинскую практику. Дальнейшее развитие предложенного подхода предполагает идентификацию двойного прокола вены, дифференцирование типа ткани в процессе введения иглы и исследование возможности определения типа кровеносного сосуда A new method for controlling the penetration of an injection needle into the vein based on measurements of electrical impedance using a mixed system of electrodes consisting of bipolar and tetrapolar parts is proposed. Alternative schemes for the arrangement of electrodes for monitoring venous puncture using the bioimpedance method have been investigated - they have a more complex design, use expensive specialized coaxial needles, do not allow to unambiguously determine the fact of a puncture of the venous vessel wall, require additional filtering of the recorded signal in order to correctly interpret the result. The effectiveness of the proposed technique was tested in experimental studies on 5 volunteers. The results of the experiments made it possible to identify 4 stages of finding the injection needle relative to the upper limb: no touching, touching the skin, being under the skin of the skin, getting into the lumen of the vein. Identification of the positions of the injection needle occurs in real time without additional filtering of the recorded signal. The method allows detecting the moment of puncture of the wall of a venous vessel with a standard injection needle, which in the future will save on the manufacture of specialized multilayer needle electrodes and introduce this method of monitoring venipuncture into medical practice. Further development of the proposed approach involves the identification of a double vein puncture, differentiation of tissue type during needle insertion, and investigation of the possibility of determining the type of blood vessel

Computational and experimental studies of the strength of full-scale samples of pipes with defects "metal loss" and "dent with groove"

2020 ◽  
Vol 10 (3) ◽  
pp. 226-233
Author(s):  
Dmitry A. Neganov ◽  
◽  
Victor M. Varshitsky ◽  
Andrey A. Belkin ◽  
◽  
...  
Keyword(s):  
Internal Pressure ◽  
Experimental Studies ◽  
Full Scale ◽  
The Other ◽  
Metal Loss ◽  
Calculation Methods ◽  
Reliable Operation ◽  
Sufficient Stability ◽  
Comparative Results ◽  
The Moment

The article contains the comparative results of the experimental and calculated research of the strength of a pipeline with such defects as “metal loss” and “dent with groove”. Two coils with diameter of 820 mm and the thickness of 9 mm of 19G steel were used for full-scale pipe sample production. One of the coils was intentionally damaged by machining, which resulted in “metal loss” defect, the other one was dented (by press machine) and got groove mark (by chisel). The testing of pipe samples was performed by applying static internal pressure to the moment of collapse. The calculation of deterioration pressure was carried out with the use of national and foreign methodical approaches. The calculated values of collapsing pressure for the pipe with loss of metal mainly coincided with the calculation experiment results based on Russian method and ASME B31G. In case of pipe with dent and groove the calculated value of collapsing pressure demonstrated greater coincidence with Russian method and to a lesser extent with API 579/ASME FFS-1. In whole, all calculation methods demonstrate sufficient stability of results, which provides reliable operation of pipelines with defects.

scholarly journals Bootstrapping Coulomb and Higgs branch operators

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Aleix Gimenez-Grau ◽  
Pedro Liendo
Keyword(s):  
Recent Work ◽  
Moment Map ◽  
Mixed System ◽  
Flavor Symmetry ◽  
Coulomb Branch ◽  
Conformal Bootstrap ◽  
General Constraints ◽  
Superconformal Theories ◽  
The Moment

Abstract We apply the numerical conformal bootstrap to correlators of Coulomb and Higgs branch operators in 4d$$ \mathcal{N} $$ N = 2 superconformal theories. We start by revisiting previous results on single correlators of Coulomb branch operators. In particular, we present improved bounds on OPE coefficients for some selected Argyres-Douglas models, and compare them to recent work where the same cofficients were obtained in the limit of large r charge. There is solid agreement between all the approaches. The improved bounds can be used to extract an approximate spectrum of the Argyres-Douglas models, which can then be used as a guide in order to corner these theories to numerical islands in the space of conformal dimensions. When there is a flavor symmetry present, we complement the analysis by including mixed correlators of Coulomb branch operators and the moment map, a Higgs branch operator which sits in the same multiplet as the flavor current. After calculating the relevant superconformal blocks we apply the numerical machinery to the mixed system. We put general constraints on CFT data appearing in the new channels, with particular emphasis on the simplest Argyres-Douglas model with non-trivial flavor symmetry.

scholarly journals Investigation of the structure of cement conglomerates

2021 ◽  
Vol 266 ◽  
pp. 03005
Author(s):  
D. N. Shabanov ◽  
E. Trambitsky ◽  
E. Borovkova
Keyword(s):  
Strain State ◽  
Residual Life ◽  
Experimental Studies ◽  
Cement Stone ◽  
Virtual Model ◽  
Structural Studies ◽  
Acoustic Sensors ◽  
Cement Pastes ◽  
The Moment ◽  
Physical And Chemical

This article describes the structural studies of a cement conglomerate, its evolution from the moment of formation to the loss of operational properties. Physical and chemical phenomena and interactions of various elements of cement stone are considered. The study of its rheology includes creating a virtual model and monitoring the formation of the structure of cement pastes by acoustic emission (AE). The results of combined experimental studies to determine the residual life of cement stone samples using AE and tensometry methods are presented. The authors created a complex for monitoring the stress-strain state of artificial conglomerates, which includes both internal and acoustic sensors.

scholarly journals Historia rozwoju Republiki Rzymskiej według Polibiusza

2013 ◽  
Vol 6 (2) ◽  
pp. 85-93
Author(s):  
Anna Ceglarska ◽  
Keyword(s):  
Roman Republic ◽  
Political Theory ◽  
Social Contexts ◽  
The State ◽  
Mixed System ◽  
The Political ◽  
Mutual Relation ◽  
Perfect System ◽  
History Of ◽  
The Moment

History of the rise of the Roman Republic as described by Polybius The aim of this article is to refer Polybius’s political theory, included in Book VI of The Histories, to the history of the rise of the Roman Republic. This theme must have been particularly significant for Polybius. For him, Rome was the most perfect example of a mixed government system, and the aim of describing its history was to show the development of this perfect system. The article presents the mutual relation of theory and history, starting with the period of kingship, up to the emergence of the democratic element, i.e. the moment when Rome acquired the mixed system of government. Both the political and social contexts of the changes are outlined. The analysis suggests that Polybius related his political theory to the history of the state he admired, thus providing the theory with actual foundations. Reconstructing his analysis makes it possible to see the history of Rome in a different light, and to ponder the system itself and its decline, even though the main objective of both Polybius and this article is to present its development.

scholarly journals THERMODYNAMIC UNCERTAINTY RELATION AS A FUNDAMENTAL ASPECT OF QUANTUM THERMODYNAMICS

2018 ◽  
pp. 17-29
Author(s):  
Anton А. Artamonov ◽  
Еvgeny Plotnikov
Keyword(s):  
Transport Properties ◽  
Uncertainty Relation ◽  
Critical Role ◽  
Silicon Crystal ◽  
Experimental Studies ◽  
Fundamental Aspect ◽  
Quantum Computers ◽  
State Control ◽  
Quantum Thermodynamics ◽  
The Moment

The paper addresses physics of thermodynamic fluctuations in temperature and energy. These fluctuations are interrelated and, hence, can affect various micro- and macro systems. It is shown that the thermodynamic uncertainty relation must be taken into account in the physics of superconductivity, in quantum computations and other branches of science, where temperature and energy fluctuations play a critical role. One of the most important applications of quantum thermodynamics is quantum computers. It is assumed that in the near future the state structures will create a specific quantum cryptocurrency obtained using quantum computing. The quantum cryptocurrency exhibits two main features: the maximum reliability (quantum protection against hacking threats) and the possibility of state control (at the moment, only large scientific state centers have quantum computers). The paper reviews the studies aimed to theoretically prove the validity of the thermodynamic uncertainty relation. This relation connects fluctuations in temperature and energy of a system. Other similar relations are considered, including the relationship between fluctuations in pressure and volume, in entropy and temperature, and others. The main purpose of the paper is to validate the thermodynamic analogue of the uncertainty relation that interconnects temperature and energy fluctuations. Experimental data was obtained on the basis of the study of the transport properties of semiconductor devices – transistors. In the experiment, the transport properties of a pair of semiconductor transistors placed on a single silicon crystal were studied. In this system, one transistor was used to determine temperature fluctuations, and the other one was employed to estimate energy fluctuations. The key role of the thermodynamic uncertainty relation in modern thermodynamics has been clarified. The performed experimental studies confirm the validity of the thermodynamic uncertainty relation.

Assay of Functional Plasminogen in Rat Plasma Applicable to Experimental Studies of Thrombolysis

2000 ◽  
Vol 84 (08) ◽  
pp. 299-306 ◽  
Author(s):  
Kristian Bangert ◽  
Sixtus Thorsen
Keyword(s):  
Plasminogen Activator ◽  
Experimental Studies ◽  
Fold Increase ◽  
Rat Plasma ◽  
Tissue Type ◽  
Plasminogen Activation ◽  
Type Plasminogen Activator ◽  
Plasmin Inhibitor

SummaryAn improved sensitive, specific, precise and accurate assay of plasminogen in rat plasma was developed. It is performed in 96-well microtiter plates and can be completed within one hour. The assay is based on activation of plasminogen by human urokinase-type plasminogen activator (uPA) and simultaneous measurement of generated plasmin with the specific plasmin substrate H-D-Val-Phe-Lys-4-nitroanilide (S-2390), using purified native rat plasminogen for calibration. The concentration of S-2390 in the final reaction mixture during the whole reaction period is much greater than the K m value (≈20 µM) for rat plasmin-cleavage of S-2390 ensuring that hydrolysis of substrate follows zero order kinetics and that the substrate produces a 20-35 fold decrease in rate of inhibition of plasmin by its target inhibitors in plasma. Analogous to the human system the target plasma inhibitors of rat plasmin are shown to be plasmin inhibitor and α-macroglobulins. Tranexamic acid (0.8 mM) is incorporated in the reaction mixture resulting in a 19-fold increase in the rate of plasminogen activation and presumably an about 50-fold decrease in the rate of inhibition of generated plasmin by plasmin inhibitor. The assay is suitable for accurate measurement of plasminogen in samples obtained from animals containing pharmacological concentrations of uPA or tissue-type plasminogen activator (tPA) in their plasma when in vitro plasminogen activation is blocked at pH 5 by collecting blood in acidic anticoagulant. Judged from in vitro experiments formation of catalytic active plasmin-α-macroglobulin complexes during massive activation of plasminogen in vivo does not interfere with the assay.

scholarly journals Electro-acupuncture reduces the need for additional anesthetics in experimental studies

2010 ◽  
Vol 25 (4) ◽  
pp. 381-384 ◽  
Author(s):  
Agamenon Honório Silva ◽  
Alberico Ximenes do Prado Neto ◽  
Sérgio Botelho Guimarães
Keyword(s):  
Stainless Steel ◽  
Electrical Stimulation ◽  
Wistar Rats ◽  
Experimental Studies ◽  
Needle Insertion ◽  
Additional Treatment ◽  
Human Right ◽  
Beneficial Effects ◽  
Group Control ◽  
Male Wistar Rats

PURPOSE: To evaluate the possible beneficial effects of electro-acupuncture in rats subjected to ketamine/xylazine (KX) intra-peritoneal (i.p.) anesthesia. METHODS: Forty-eight male Wistar rats were distributed in four equal groups. All rats received i.p. injections of ketamine (90 mg/kg) +xylazine (10 mg/kg) anesthesia. Basal values group (control) rats (BV) received no additional treatment. The equivalent of the human right ST36 (Zusanli) and CV-12(Zhongwan) acupoints were chosen for needling and electrical stimulation. AC rats were needled with sterilized disposable stainless steel needles at right ST36 and CV12 acupoints; needles were retained for 30 minutes. EAC10 rats, after needle insertion as described, had electrodes connected to both needles and to an electro stimulator model NKL EL-608; pulsed square waves, 10 Hz, 10 mA, was applied for 30 minutes. EAC100 rats were submitted to EA as described. However, a greater frequency (100 Hz) was used. RESULTS: Thirty-seven rats remained under adequate anesthetic level during the experiment. However, maintenance anesthesia was required by 11 rats. Need for additional anesthesia decreased to 9.1% in EAC100 rats compared to BV (36.3%). CONCLUSION: Both the AC and the EAC10/100 prolong the anesthetic effect of the combination Ketamine-xylazine in rats, allowing longer duration of anesthesia with a lower dose of anesthetic, thereby reducing the occurrence of complications.

scholarly journals RESEARCH OF TECHNICAL CHARACTERISTICS OF NEW TYPES OF COUPLINGS

2020 ◽  
pp. 113-121
Author(s):  
Oleksii Tokarchuk ◽  
Yurii Polievoda
Keyword(s):  
Elastic Element ◽  
Rational Design ◽  
Experimental Studies ◽  
Bending Moment ◽  
Operational Reliability ◽  
Modern Technology ◽  
Operating Conditions ◽  
The Moment ◽  
Working Bodies ◽  
Moment Of Resistance

Dynamic loads that occur during the operation of existing couplings cause significant shock loads, which leads to rapid wear of the surfaces of the couplings and shortens the service life. Modern technology faces the task of improving the operational reliability of the working bodies and drives of machines. One way to solve this problem is to develop and use high-precision and low-dynamic safety couplings. In this regard, the question of developing new designs of safety couplings that reduce impact loads and increase the reliability and durability of machinery is relevant. The synthesis of structural and kinematic schemes of ball, cam and planetary safety couplings, the method of their calculation in combination with the nature of the change in the moment of resistance on the working body of the equipment. The article conducts a set of theoretical and experimental studies to determine their rational design, kinematic and dynamic parameters that will satisfy the operating conditions of machines and mechanisms. A force analysis of the elastic element (ring spring) was performed. The scheme of loading of an elastic element by two forces and other settlement schemes are constructed, namely: equivalent system; force diagrams for determining the load torque; force schemes for determining the unit moment; schemes of total bending moment; force schemes to determine the total unit moment. During static experimental studies of the developed ball safety couplings, the nature of their operation was established, the maximum torque at the two stages of operation of the couplings was determined and a comparative analysis between the results of theoretical and experimental studies was performed. The positive results of experimental researches of the developed coupling and theoretical positions which can be applied to a substantiation and a choice of rational parameters of the developed designs of couplings and their engineering designing were confirmed.

scholarly journals A Simulation Framework for Passive Acoustic Thermometry of Homogenous Materials

2019 ◽  
Author(s):  
Hossein Amiri ◽  
Bahador Makkiabadi ◽  
Ali Khani ◽  
Soheil Ahmadzade Irandoost
Keyword(s):  
Acoustic Radiation ◽  
Experimental Studies ◽  
Temperature Reconstruction ◽  
Simulation Framework ◽  
Processing Parameter ◽  
Temperature Estimation ◽  
Practical Experiment ◽  
The Moment ◽  
Passive Acoustic ◽  
The Cost

Purpose: Passive Acoustic Thermometer (PAT) is a safe method for internal temperature estimation that works based on acoustic radiation of materials with a specific temperature. Several experimental studies have been carried out so far in the field of PAT. While, to the best of our knowledge, there is no simulation-based research reported yet. Materials and Methods: In this article (for the first time) we proposed a simulation framework for evaluating the PAT methodologies. This framework supports the generation of acoustic radiation, signal processing, parameter estimation, and temperature reconstruction processes. At the moment, the proposed framework estimates the temperature in the frequency domain and uses the frequency spectrum of the acquired ultrasound signals captured by a single transducer. Results: Using the proposed framework, we tried to implement previously practical experiments and the results of the simulation are consistent with those of the practical experiment. The mean error of temperature estimation was below 0.45 °C. The results show that it is possible to use this framework to evaluate the PAT in different scenarios. Conclusion: Therefore, this method enhances the possibility of examination of different conditions and algorithms. It also reduces the cost of practical experiment.

scholarly journals INVESTIGATION OF THE INFLUENCE OF PRESSING BELTS TENSION OF THE BACK CIRCUIT OF PRESS - SELECTIVE PR-1.5

2018 ◽  
Vol 13 (2) ◽  
pp. 76-76
Author(s):  
Валерий Белов ◽  
Valeriy Belov ◽  
Леонид Рыбаков ◽  
Leonid Rybakov ◽  
Светлана Овчукова ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Experimental Studies ◽  
Field Research ◽  
Test Protocol ◽  
Optimal Value ◽  
The Stability ◽  
The Moment ◽  
The Mathematical Model ◽  
Elastic Characteristics

A brief analysis of suspension mechanisms and ways to improve the quality of press harvesting for flax harvesting is considered. By researching the mathematical model, the authors prove the possibility of increasing the stability of the elastic characteristics of the suspension mechanisms by changing the angle between the levers or changing the geometry of the structure, for example, the attachment point of a two-arm lever. Particular attention is drawn to the new term “reduced rigidity” of the suspension mechanism. Using this notion and the method of its determination, the authors recommend determining the optimal value of the reduced stiffness of the suspension in the way of mathematical modeling and using this indicator as the main optimization parameter. The results of theoretical and experimental studies were presented by the authors in the form of elastic characteristics of the suspension mechanisms. When conducting a study of the mathematical model, it is suggested to take into account the condition of equality of the maximum values of the moments of forces from the action of the tension forces of the belts or the mass of the working element and the moment of forces acting on the side of the tension springs. During the research of the suspension mechanism, the actual dimensions of the PR-1.5 baler design were adopted. At the same time, we briefly describe the design of the improved tensioning mechanism of a baler for flax harvesting. A rather detailed analysis is given by the authors of the obtained elastic characteristics of the suspension mechanism. Some new features of the elastic characteristics of the suspension mechanism that have not been previously detected are described. To confirm the correctness of the reasoning, the authors implemented their research in a real press-picker and conducted field research that confirmed the possibility of improving the quality of the upgraded version of the machine. To confirm the results of the research, the authors presented a fragment of the field test protocol. The task is solved, uniformity of the roll density is ensured and its density is increased.

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