Thyroid Dysfunction and Their Relation to Cardiovascular Risk Factors such as Lipid Profile, hsCRP, and Waist Hip Ratio in Korea

AbstractThe aim of this study was to determine the prevalence of thyroid dysfunction and its association with cardiovascular risk factors in an adult Bulgarian population. 2402 subjects were studied, 1347 female, 20–94y (median: 48.0y) and 1055 male, 20–91y (median: 45.5y). Body weight, height, waist circumference, arterial blood pressure, TSH, FT4 and lipids were measured. Known hypothyroidism was reported by 53 subjects (2.2%) and hyperthyroidism by 20 (0.8%). New hypothyroidism was found in 98 (4.1%), [subclinical (3.2%), overt (0.9%)]. New hyperthyroidism was found in 68 (2.9%), [subclinical (2.5%), overt (0.4%)]. New diagnosis of hypothyroidism and hyperthyroidism was entered in 84% and 87% in male subjects and 60% and 65% in the females respectively. Arterial hypertension was present in 40% of the women and in 47% of the men (p<0.001) and was more prevalent in hypothyroidism. Abdominal obesity and dyslipidemia were more prevalent in males and hypothyroid subjects. Arterial hypertension depended on age, gender and lipid status but not on thyroid function. CHD history depended on thyroid function and age. Conclusion: Most cases of thyroid dysfunction were undiagnosed, especially in the males. CV risk factors were more prevalent in the males with thyroid dysfunction a major determinant of CHD, but not hypertension.

Download Full-text

Serum lipid profile and its association with some cardiovascular risk factors in an urban chinese population

Pathology ◽

10.3109/00313029309090854 ◽

1993 ◽

Vol 25 (4) ◽

pp. 344-350 ◽

Cited By ~ 17

Author(s):

E. Lau ◽

J. Woo ◽

C.S. Cockram ◽

A. Chan ◽

C.W.K. Lam ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Cardiovascular Risk Factors ◽

Chinese Population ◽

Serum Lipid ◽

Serum Lipid Profile

Download Full-text

Impaired HDL cholesterol efflux capacity in systemic lupus erythematosus patients is related to subclinical carotid atherosclerosis

Rheumatology ◽

10.1093/rheumatology/keaa038 ◽

2020 ◽

Vol 59 (10) ◽

pp. 2847-2856 ◽

Cited By ~ 1

Author(s):

Hiurma Sánchez-Pérez ◽

Juan Carlos Quevedo-Abeledo ◽

Laura de Armas-Rillo ◽

Íñigo Rua--Figueroa ◽

Beatriz Tejera-Segura ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Cardiovascular Risk Factors ◽

Cholesterol Efflux ◽

Carotid Atherosclerosis ◽

Vitro Assay ◽

Carotid Plaques ◽

Cholesterol Efflux Capacity ◽

Related Data

Abstract Objectives Lipid profiles appear to be altered in SLE patients due to disease activity and inflammation. Cholesterol efflux capacity (CEC) is the ability of high-density lipoprotein cholesterol to accept cholesterol from macrophages. CEC has been linked to cardiovascular events in the general population and is impaired in SLE patients. The aim of this study was to establish whether CEC is related to subclinical carotid atherosclerosis in SLE patients. Methods The present report is of a cross-sectional study that encompassed 418 individuals: 195 SLE patients and 223 controls. CEC, using an in vitro assay, and lipoprotein serum concentrations were assessed in patients and controls. Carotid intima-media thickness and carotid plaques were evaluated in SLE patients. A multivariable analysis was performed to study the relationship of CEC to SLE-related data, lipid profile and subclinical carotid atherosclerosis. Results CEC was downregulated in SLE patients [8.1 (4.2) % vs 16.9 (10.4) %, P = 0.004). This occurred independently of traditional cardiovascular risk factors, statin use or other variations in the lipid profile related to the disease. Traditional cardiovascular risk factors, both in patients and controls, and SLE-related data such as activity, severity or damage were not associated with CEC. After multivariable regression analysis including lipid profile–related molecules, CEC was inversely and independently associated with the presence of carotid plaques in SLE patients [odds ratio 0.87 (95% CI: 0.78, 0.97), P = 0.014]. Conclusion CEC is impaired in SLE patients independently of other inflammation-related lipid profile modifications that occur during the disease. CEC is associated with carotid plaques in SLE patients.

Download Full-text

Abnormal lipid profile and hyperinsulinaemia after a mixed meal: additional cardiovascular risk factors in young adults born preterm

Diabetologia ◽

10.1007/s00125-008-1029-5 ◽

2008 ◽

Vol 51 (7) ◽

pp. 1269-1275 ◽

Cited By ~ 22

Author(s):

J. Rotteveel ◽

M. M. van Weissenbruch ◽

J. W. R. Twisk ◽

H. A. Delemarre-Van de Waal

Keyword(s):

Risk Factors ◽

Young Adults ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Cardiovascular Risk Factors ◽

Mixed Meal

Download Full-text

High Levels of Cardiovascular Risk Factors among Pakistanis in Norway Compared to Pakistanis in Pakistan

Journal of Obesity ◽

10.1155/2011/163749 ◽

2011 ◽

Vol 2011 ◽

pp. 1-5 ◽

Cited By ~ 7

Author(s):

Naeem Zahid ◽

Haakon E. Meyer ◽

Bernadette N. Kumar ◽

Bjørgulf Claussen ◽

Akhtar Hussain

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Lipid Profile ◽

Total Cholesterol ◽

Cardiovascular Risk Factors ◽

Additional Risk ◽

Increased Risk ◽

Males And Females ◽

Diabetes And Obesity

Objectives. Previous studies have shown that the Norwegian-Pakistanis had considerably higher prevalence for diabetes and obesity compared to Norwegians. We studied the additional risk of obesity, dyslipidemia, and hypertension among Pakistanis in Norway compared to Pakistanis living in Pakistan.Method. 770 Norwegian-Pakistani adults (53.9% men and 46.1% women) born in Pakistan from two surveys conducted in Norway between 2000 and 2002 were compared with a sample of 1230 individuals (29.1% men and 70.9% women) that participated in a survey in Pakistan in 2006.Results. Both populations had similar height, but Norwegian-Pakistanis had considerably higher mean weight. Of the Norwegian-Pakistanis, 56% of the males and 40% of the females had a BMI above 25 kg/m2, as opposed to 30% and 56% in Pakistan, for males and females, respectively. Norwegian-Pakistanis had higher total cholesterol.Conclusion. Obesity and an unfavourable lipid profile were widely prevalent in both populations; the highest level was recorded amongst those living in Norway. The increased risk for obesity and dyslipidemia may be ascribed to change of lifestyle after migration.

Download Full-text

Relationship between anthropometric indicators and risk factors for cardiovascular disease in adults and older adults of Rio Branco, Acre

Revista de Saúde Pública ◽

10.11606/s1518-8787.2020054001088 ◽

2020 ◽

Vol 54 ◽

pp. 24

Author(s):

Nathalia Silva de Lima Loureiro ◽

Thatiana Lameira Maciel Amaral ◽

Cledir De Araújo Amaral ◽

Gina Torres Rego Monteiro ◽

Maurício Teixeira Leite de Vasconcellos ◽

...

Keyword(s):

Risk Factors ◽

Older Adults ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Population Based ◽

Cross Sectional Study ◽

Obese Adults ◽

Cross Sectional ◽

Adult Men ◽

Waist Hip Ratio

OBJECTIVE: To analyze the association between anthropometric variables and cardiovascular risk factors in adults and older adults of Rio Branco, Acre. METHODS: A population-based cross-sectional study with 641 adults and 957 older adults was conducted. The statistical analyses consisted of the distribution of anthropometric variables according to the cardiovascular risk factors by frequency and dispersion measures. Pearson’s correlation coefficient and prevalence ratios (PR) were estimated with their respective 95% confidence intervals (95%CI) using the SPSS® version 20.0. RESULTS: Moderate correlations were obtained in adult men for waist-hip ratio and total cholesterol (r = 0.486; p < 0.001) and for waist-hip and triglyceride ratios (r = 0.484; p < 0.001). The highest prevalence of hypertension and diabetes in adults were observed in men; in the older adults, the prevalence of hypertension was above 65% in both sexes. The prevalence of dyslipidemia was above 78% in obese adults and older adults. When analyzing the associations, a higher strength of association was found between arterial hypertension and waist-to-stature ratio (PR = 13.42; 95%CI 12.58–14.31) and body mass index greater than 30 kg/m2 (PR = 6.61; 95%CI 6.34–6.89) in adult men. In the analysis of diabetes, the waist-hip ratio presented greater robustness in the association for women (PR = 7.53; 95%CI 6.92–8.20) and men (PR = 9.79; 95%CI 9.14–10.49). CONCLUSION: Anthropometric variables are important predictors of cardiovascular risk; however, their assessments should be performed independently, according to sex and age group.

Download Full-text