scholarly journals Reducing bias in risk indices for COVID-19

2022 ◽  
Vol 17 (s1) ◽  
Author(s):  
Michał Paweł Michalak ◽  
Jack Cordes ◽  
Agnieszka Kulawik ◽  
Sławomir Sitek ◽  
Sławomir Pytel ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Spatial Heterogeneity ◽  
Disease Burden ◽  
Risk Indices ◽  
Study Evaluation ◽  
Dynamical Properties ◽  
Time Periods ◽  
Regional Disease ◽  
Over Time

Spatiotemporal modelling of infectious diseases such as coronavirus disease 2019 (COVID-19) involves using a variety of epidemiological metrics such as regional proportion of cases and/or regional positivity rates. Although observing changes of these indices over time is critical to estimate the regional disease burden, the dynamical properties of these measures, as well as crossrelationships, are usually not systematically given or explained. Here we provide a spatiotemporal framework composed of six commonly used and newly constructed epidemiological metrics and conduct a case study evaluation. We introduce a refined risk estimate that is biased neither by variation in population size nor by the spatial heterogeneity of testing. In particular, the proposed methodology would be useful for unbiased identification of time periods with elevated COVID-19 risk without sensitivity to spatial heterogeneity of neither population nor testing coverage.We offer a case study in Poland that shows improvement over the bias of currently used methods. Our results also provide insights regarding regional prioritisation of testing and the consequences of potential synchronisation of epidemics between regions. The approach should apply to other infectious diseases and other geographical areas.

scholarly journals Modeling the Risk of Infectious Diseases Transmitted by Aedes aegypti Using Survival and Aging Statistical Analysis with a Case Study in Colombia

Mathematics ◽  
2021 ◽  
Vol 9 (13) ◽  
pp. 1488
Author(s):  
Henry Velasco ◽  
Henry Laniado ◽  
Mauricio Toro ◽  
Alexandra Catano-López ◽  
Víctor Leiva ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Infectious Diseases ◽  
Survival Time ◽  
Young Female ◽  
The Other ◽  
Principal Vector ◽  
New Knowledge ◽  
Wear And Tear ◽  
Over Time

Many infectious diseases are deadly to humans. The Aedes aegypi mosquito is the principal vector of infectious diseases that include chikungunya, dengue, yellow fever, and zika. Some factors such as survival time and aging are vital in its development and capacity to transmit the pathogens, which in turn are affected by environmental factors such as temperature. In this paper, we consider aging as the biological wear and tear presented in some mosquito populations over time, whereas survival is considered as the maximum time that a mosquito lives. We propose statistical methods that are commonly used in engineering for reliability analysis to compare transmission riskiness among different mosquitoes. We conducted a case study in three Colombian cities: Bello, Riohacha, and Villavicencio. In this study, we detected that the Aedes aegypi female mosquitoes in Bello live longer than in Riohacha and Villavicencio, and the females in Riohacha live longer than those in Villavicencio. Regarding aging, the females from Riohacha age slower than in Villavicencio and the latter age slower than in Bello. Mosquito populations that age slower are considered young and the other ones are old. In addition, we detected that the females from Bello in the temperature range of 27 ∘C–28 ∘C age slower than those in Bello at higher temperatures. In general, a young female has a higher risk of transmitting a disease to humans than an old female, regardless of its survival time. These findings have not been previously reported in studies of this type of infectious diseases and contributed to new knowledge in biomedicine.

Case Study: Evaluation of an Older Woman With Dementia at a University Speech and Hearing Clinic

2001 ◽  
Vol 6 (1) ◽  
pp. 2-3
Author(s):  
Andrea Tobochnik ◽  
Kathy Esnlen ◽  
Jennifer Nobles Cora ◽  
Rene Watkins
Keyword(s):  
Older Woman ◽  
Study Evaluation

CASE STUDY: Evaluation of Different Cooling Systems in Lactating Heat-Stressed Dairy Cows in a Semi-Arid Environment

2007 ◽  
Vol 23 (5) ◽  
pp. 546-555 ◽  
Author(s):  
R. Burgos ◽  
L.J. Odens ◽  
R.J. Collier ◽  
L.H. Baumgard ◽  
M.J. VanBaale
Keyword(s):  
Dairy Cows ◽  
Arid Environment ◽  
Cooling Systems ◽  
Study Evaluation ◽  
Semi Arid

When Culturally Significant Songs are Decontextualised: The Initiation Song Somagwaza, A Case Study

2018 ◽  
Vol 28 (2) ◽  
Author(s):  
T Dowling ◽  
Somikazi Deyi ◽  
Anele Gobodwana
Keyword(s):  
Qualitative Research ◽  
Comparative Method ◽  
Popular Song ◽  
Focus Group Discussions ◽  
Group Discussions ◽  
Ritual Music ◽  
Constant Comparative Method ◽  
Small Focus ◽  
Over Time

While there have been a number of studies on the decontextualisation and secularisation of traditional ritual music in America, Taiwan and other parts of the globe, very little has been written on the processes and transformations that South Africa’s indigenous ceremonial songs go through over time. This study was prompted by the authors’ interest in, and engagement with the Xhosa initiation song Somagwaza, which has been re-imagined as a popular song, but has also purportedly found its way into other religious spaces. In this article, we attempted to investigate the extent to which the song Somagwaza is still associated with the Xhosa initiation ritual and to analyse evidence of it being decontextualised and secularised in contemporary South Africa. Our methodology included an examination of the various academic treatments of the song, an analysis of the lyrics of a popular song, bearing the same name, holding small focus group discussions, and distributing questionnaires to speakers of isiXhosa on the topic of the song. The data gathered were analysed using the constant comparative method of analysing qualitative research.

Drinking-Water Quality and Intestinal Infectious Diseases in a Colombian Department, 2010-2016

2020 ◽  
pp. 21-29
Author(s):  
Dora Cardona Rivas ◽  
Militza Yulain Cardona Guzmán ◽  
Olga Lucía Ocampo López
Keyword(s):  
Water Quality ◽  
Drinking Water ◽  
Infectious Diseases ◽  
Disease Burden ◽  
Social Protection ◽  
Drinking Water Quality ◽  
World Health ◽  
The Social ◽  
Etiological Agents ◽  
Health Organization

Objective: To characterize the burden of intestinal infectious diseases attributable to drinking-water quality in 27 municipalities in the central region of Colombia. Materials and methods: A time-trend ecological study. The drinking-water quality of the National Institute of Health and the Institute of Hydrology, Meteorology and Environmental Studies was identified. The disease burden was calculated based on the mortality registered in the National Department of Statistics and the records of morbidity attended by the Social Protection Integrated Information System. The etiological agents reported in morbidity records and the observation of environmental conditions in the municipalities of the study were included. The disease burden was determined according to the methodology recommended by the World Health Organization (WHO).

Thinning in mature eastern white pine: 43-year case study

2002 ◽  
Vol 78 (4) ◽  
pp. 539-549 ◽  
Author(s):  
Paul D Anderson ◽  
John C Zasada ◽  
Glen W Erickson ◽  
Zigmond A Zasada
Keyword(s):  
Genetic Diversity ◽  
Dna Analysis ◽  
Large Diameter ◽  
White Pine ◽  
Thinning Intensity ◽  
Pine Regeneration ◽  
Volume Production ◽  
Pine Stands ◽  
Over Time

A white pine (Pinus strobus L.) stand at the western margin of the species range, approximately 125 years of age at present, was thinned in 1953 from 33.5 m2 ha-1 to target residual basal areas of 18.4, 23.0, 27.5, and 32.1 m2 ha-1 . Repeated measurement over the following 43-years indicated that the greatest total volume production and the greatest number of large diameter trees occurred in the unit of highest residual density. Over time, the distribution of stems was predominantly random although mortality between 1979 and 1996 resulted in a tendency for clumping in the 23.0 and 27.5 m2 ha-1 treatments. DNA analysis indicated that thinning intensity had little effect on the genetic diversity of residual white pine. This study suggests that mature white pine stands in northern Minnesota may be managed at relatively high densities without loss of productivity. However, regardless of overstory density, there was little or no white pine regeneration occurring in this stand. Key words: thinning, growth, genetic diversity, molecular markers, spatial pattern, regeneration

scholarly journals Appraising psychotherapy case studies in practice-based evidence: introducing Case Study Evaluation-tool (CaSE)

2021 ◽  
Vol 34 (1) ◽  
Author(s):  
Greta Kaluzeviciute
Keyword(s):  
Case Studies ◽  
Evaluation Criteria ◽  
Internal Validity ◽  
Knowledge Generation ◽  
Evaluation Tool ◽  
Third Way ◽  
Study Evaluation ◽  
Essential Components ◽  
Randomised Controlled

AbstractSystematic case studies are often placed at the low end of evidence-based practice (EBP) due to lack of critical appraisal. This paper seeks to attend to this research gap by introducing a novel Case Study Evaluation-tool (CaSE). First, issues around knowledge generation and validity are assessed in both EBP and practice-based evidence (PBE) paradigms. Although systematic case studies are more aligned with PBE paradigm, the paper argues for a complimentary, third way approach between the two paradigms and their ‘exemplary’ methodologies: case studies and randomised controlled trials (RCTs). Second, the paper argues that all forms of research can produce ‘valid evidence’ but the validity itself needs to be assessed against each specific research method and purpose. Existing appraisal tools for qualitative research (JBI, CASP, ETQS) are shown to have limited relevance for the appraisal of systematic case studies through a comparative tool assessment. Third, the paper develops purpose-oriented evaluation criteria for systematic case studies through CaSE Checklist for Essential Components in Systematic Case Studies and CaSE Purpose-based Evaluative Framework for Systematic Case Studies. The checklist approach aids reviewers in assessing the presence or absence of essential case study components (internal validity). The framework approach aims to assess the effectiveness of each case against its set out research objectives and aims (external validity), based on different systematic case study purposes in psychotherapy. Finally, the paper demonstrates the application of the tool with a case example and notes further research trajectories for the development of CaSE tool.

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