scholarly journals REVIEW ARTICLE ON AYURVEDIC APPROACH SANDHIGAT VATA W.S.R. TO OSTEOARTHRITIS

2021 ◽  
Vol 9 (8) ◽  
pp. 1882-1887
Author(s):  
Tanmane C. S. ◽  
Akram Yusuf Khan
Keyword(s):  
Modern Science ◽  
Degenerative Joint Disease ◽  
Review Article ◽  
The Body ◽  
Joint Disease ◽  
Degenerative Diseases ◽  
Everyday Activities ◽  
Disease Occurrence ◽  
Joint Problem ◽  
Modern Era

Ayurveda the science of life, healthy and higher longevity are always desirable from it. In today's modern era due to atmosphere, lack of proper healthy diet, travelling and old age etc. metabolic and degenerative disease of connective tissue and the joint problem is quite affluent, and the disease occurrence starts early. Sandhi- gatavata (Osteoarthritis) is a disease due to vitiated Vata in various Sandhi or joints in the body. It is de- scribed under Vatavyadhi in almost every literature of Ayurveda. Clinically the description of Sandhigata Vata explained in theclassical texts is like the condition osteoarthritis in modern science. Sandhigata Vata is described under Vatavyadhi in all the Samhitas and Sangraha Granthas. Ayurveda highlighted degenerative diseases under the concepts like “Dhatu Saithilyam” and “Dhatu Kshayam”. Sandhigata Vata is one such disease, which needs a specific target of therapeutic intervention to check or slow down the process of “Dhatu Kshaya” and to pacify Vata. Sandhigatavata may be correlated with degenerative joint disease or Osteoarthritis, which in turn cripples the patient to the maximum, extends and reduces the total working ca- pacity of the person. It limits everyday activities such as walking, dressing, bathing etc., thus making indi- viduals handicapped. Keywords: Sandhigatavata, Osteoarthritis, Joint, Vata Vyadhi.

scholarly journals A review on Sandhigatavata and its Management Principles

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Nagesh Gandagi ◽  
Shubhangi Patil
Keyword(s):  
Therapeutic Intervention ◽  
Modern Science ◽  
Degenerative Joint Disease ◽  
Joint Disease ◽  
Degenerative Diseases ◽  
Working Capacity ◽  
Specific Target ◽  
Everyday Activities

In the Ayurvedic classics the aetiopathogenesis and symptomatology of Sandhigata vata is described in concise form. Clinically the description of Sandhigata vata explained in the classical texts is similar to the condition osteoarthritis in modern science. Sandhigatavata is described under Vatavyadhi in all the Samhitas and Sangraha Granthas. In Vriddhavastha, all Dhatus undergo Kshaya, Thus leading to Vataprakopa and making individual prone to many diseases. Among them Sandhigatavata stands  top in the list. Having the symptoms like pain, swelling, crepitus, and restricted joint movements. Ayurveda highlighted degenerative diseases under the concepts like “Dhatu saithilyam” and “Dhatu kshayam”. Sandhigata Vata is one of such disease, which needs a specific target of therapeutic intervention to check or slow down the process of “Dhatu kshaya” and to pacify Vata. Sandhigatavata may be correlated with degenerative joint disease or Osteoarthritis, which in turn cripples the patient to the maximum, extends and reduces the total working capacity of the person. It limits everyday activities such as walking, dressing, bathing etc., thus making individual handicapped

scholarly journals CRITICAL STUDY OF TVAK IN THE VIEW OF MODERN SCIENCE: A REVIEW ARTICLE

2021 ◽  
Vol 9 (8) ◽  
pp. 1795-1799
Author(s):  
Ishan Malhotra ◽  
Sakshi Sakshi ◽  
Subhash Upadhyay
Keyword(s):  
Direct Contact ◽  
External Surface ◽  
Modern Science ◽  
Review Article ◽  
The Body ◽  
Critical Study ◽  
Entire Body ◽  
Internal Structures ◽  
Normal Colour ◽  
Modern Era

In Ayurveda, the term Tvak, Twacha and Charma are frequently used to denote the skin. Tvak is described as the organ which covers the external surface of the entire body. Tvak and its related diseases have great importance because these are easily noticeable. It is the first part of the body that is in direct contact with any harmful sub- stances or infective microorganisms. It protects the internal structures of the body from injury or infections and regulates the temperature of the body. Skin is also the beauty of a human being. Therefore, it should be protected from any abnormal conditions. Ayurveda Acharyas have described Tvak many years ago. They explained each layer of Tvak in meaningful sequences, its related diseases and measurement of each layer. They also explained that it maintains the normal colour of individuals and conveys the sensation of touch. Some topics of Ayurveda are easy to understand, and some topics become easy if we study along with modern science. So, for a proper un- derstanding of the concept of Tvak, it is very essential to correlate it with modern science and elaborate according to the modern era. Keywords: Tvak, Sparshanendriya, Sharirsthan, Santanika, Vrihi, Skin, Dermis, Epidermis

Diagnosis of shoulder instability in dogs and cats: a retrospective study

1998 ◽  
Vol 34 (1) ◽  
pp. 42-54 ◽  
Author(s):  
JF Bardet
Keyword(s):  
Shoulder Instability ◽  
Shoulder Joint ◽  
Glenohumeral Joint ◽  
Degenerative Joint Disease ◽  
The Body ◽  
Joint Disease ◽  
Glenohumeral Instability ◽  
The Past ◽  
Arthroscopic Findings ◽  
Stability Results

The glenohumeral joint is a remarkable articulation providing the greatest range of motion of any joint in the body. Glenohumeral stability results from several mechanisms, including those that do not require expenditure of energy by muscle ("passive mechanisms") and those that do ("active mechanisms"). Glenohumeral instability has been recognized in 47 shoulders of 45 dogs and one cat. Cases are presented because of chronic foreleg lameness. Shoulder joint pain is obviated by the orthopedic examination. Only 57% of the involved shoulders presented with degenerative joint disease. Signs of instability are recognized under anesthesia using a craniocaudal or mediolateral drawer sign or both. This report describes the radiographic and arthroscopic findings of shoulder instability. Arthroscopy of the shoulder joint allows identification of all intra-articular pathologies. Shoulder instability, not fully recognized in the past, appears to be the most common cause of shoulder lameness in the dog.

Curcumin as adjuvant therapy to Meloxicam in treatment of patients with knee Osteoarthritis; Evaluation of antioxidant activity

2020 ◽  
pp. 71-81
Keyword(s):  
Oxidative Stress ◽  
Serum Level ◽  
Knee Osteoarthritis ◽  
Physical Function ◽  
Oxford Knee Score ◽  
Degenerative Joint Disease ◽  
The Body ◽  
Joint Disease ◽  
Controlled Study ◽  
Antioxidant Parameters

Osteoarthritis (OA) is a chronic degenerative joint disease that doubled in prevalence since the mid of 20th century most commonly due to obesity and aging. Osteoarthritis can affect any joint in the body. The pathogenesis of OA is multifactorial influenced by range of biochemical and mechanical factors. Oxidative stress is described to play an important role in many diseases including OA. Accumulating evidences suggested the beneficial effect of anti-oxidants for reducing OA severity. Curcumin is a well-known antioxidant agent that acts by different mechanisms in modulating oxidative stress status. This study was designed to evaluate the antioxidant effect of curcumin as adjuvent therapy to a non-steroidal anti-inflammatory drug, meloxicam, in the management of knee osteoarthritis. This prospective open-labelled randomized controlled study was carried out on forty-two eligible patients who were allocated in two groups, serum superoxide dismutase 3 (SOD3) and glutathione reductase (GR) were measured at baseline and after 3 months of the study. Pain and physical function assessment were evaluated by oxford knee score (OKS). Results illustrated highly significant improvement in pain and physical function scores when curcumin used as adjuvant to meloxicam, also curcumin supplementation resulted in significant increase in SOD3 serum level and only a modest decrease in GR serum level when compared to meloxicam alone. In conclusion, this study demonstrated benefit of curcumin when used in combination with meloxicam over using meloxicam alone in modulating antioxidant parameters in blood, in addition to significantly improving pain and physical function after 3 months of treatment.

A Pinch of Salt - Its effect on health

2016 ◽  
Vol 1 (3) ◽  
Author(s):  
Dr. Komal Vilas Chavda ◽  
Dr. Mahesh Vyas ◽  
Dr. H.A. Vyas
Keyword(s):  
Modern Science ◽  
The Body ◽  
Modern View ◽  
Ancient Science ◽  
Vedic Literature ◽  
Excessive Consumption ◽  
The Right ◽  
Modern Era ◽  
Harmful Effects ◽  
Lifestyle Patterns

Ayurveda is an ancient science having its roots in Vedic literature which describes certain rules and regulations as a way of living. Over the ages with the advancement of technology, there have been tremendous changes in the lifestyle patterns of the individuals. The Principles of Ayurveda science are the same but it is imperative to match up and draw an analogy with the modern evidences and discover the innovation in them. Gramya Aahara is one such type of diet that is prevalent in the society and is the cause of various diseases. Ati Lavana (excessive consumption of salt) is one of the components mentioned in it. The challenge lies in understanding the dogmas of Ayurveda science thoroughly and also to implement them in this modern era. The harmful effects of salt are propounded by the Ayurveda classics as well as the modern science. This is an attempt to discuss about the excessive consumption of salt from the Ayurveda as well as modern view. This will provide succor in adopting the right manner of consumption of salt pertaining to the requirements of the body.

scholarly journals JANU SANDHIGATAVATA: A COMPREHENSIVE REVIEW OF THE AYURVEDIC LITERATURE

2020 ◽  
pp. 18-20
Author(s):  
Biswajit Dash ◽  
Rabindranath Acharya
Keyword(s):  
Knee Joint ◽  
Range Of Motion ◽  
Functional Disability ◽  
Weight Bearing ◽  
Age Factors ◽  
Pharmacological Therapy ◽  
The Body ◽  
Joint Disease ◽  
Everyday Activities ◽  
Common Complaint

Janusandhigatavata is also correlated to Knee osteoarthritis due to resemblance in sign and symptoms i.e. joint pain, stiffness, muscle weakness, swelling of knee joint, deformed joint, reduced range of motion and loss of use of the joints and cracking sounds. When the vitiated vata lodges in janusandhi (knee joint) it is considered as Janusandhigatavata. In Ayurvedic classics Sandhigatavata is among eighty Nanatmaja Vata Vyadhi. The aetiopathogenesis, symptoms and treatment of Sandhigata vata is described under Vatavyadhi which is found in a very concise form. Among joint disease, Osteoarthritis is often seen out of which the functional disability in the knee joint is incredibly common in elderly. The approaches in therapies mainly carried out are physiotherapy or pharmacological therapy, but these approaches are limited over time by their cost and/or side effects. It is characterized by pain, shiftiness with decreased range of motion in the knee joint which is very common complaint for many people. With the advancement in working pattern and age-factors has become prime cause for aggravation of Vata dosha, which does dhatukshaya (depletion of tissues) and Balakshaya (reduced strength). Knee joint is weight bearing, strongest and most important joint in the body. Movements at the knee joint are essential for all everyday activities, including walking, running, sitting and standing. Different modalities of treatment have been explained in the Ayurvedic classics to tackle the condition effectively. Here, an attempt has been made for a systematic review on this disease with an approach to Ayurvedic management.

scholarly journals Stromal cell-derived factor-1 as a potential therapeutic target for osteoarthritis and rheumatoid arthritis

2019 ◽  
Vol 10 ◽  
pp. 204062231988253 ◽  
Author(s):  
Robert Bragg ◽  
William Gilbert ◽  
Ahmed M. Elmansi ◽  
Carlos M. Isales ◽  
Mark W. Hamrick ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Therapeutic Target ◽  
Animal Studies ◽  
Stromal Cell ◽  
Degenerative Joint Disease ◽  
The Body ◽  
Joint Disease ◽  
Endochondral Bone Formation ◽  
Potential Therapeutic Target ◽  
Stromal Cell Derived Factor

With age, joints become subject to chronic inflammatory processes that lead to degeneration of articular cartilage. Although multifactorial, cytokines have been shown to play a role in the pathogenesis of these chronic disease states. Stromal cell-derived factor 1 (SDF-1) is a chemokine that has been shown to be active in homeostatic mechanisms and developmental processes throughout the body, such as endochondral bone formation. SDF-1 plays a role in the transition from cartilage to bone. Although it has been shown to be a factor in normal development, it has also been shown to involve in the pathogenesis of rheumatoid arthritis (RA) and osteoarthritis (OA). In RA, SDF-1 has been shown to stimulate the recruitment of proinflammatory cells, as well as osteoclasts to the synovium, aiding in the facilitation of synovial degradation. Similarly, in OA, SDF-1 has been shown to regulate key proteins involved in the degradation of the cartilage of the joint. Because of its role in degenerative joint disease, SDF-1 has been investigated as a potential therapeutic target. Animal studies have been employing SDF-1 inhibitors, such as AMD3100 and T140, to study their effects on attenuating degenerative joint disease. These studies have shown promising results in slowing the progression of cartilage degradation and could potentially be used as therapeutic target for humans OA and RA.

scholarly journals Review Article: Present Perspectives of Hyperthyroidism during Pregnancy

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Meena S. Farman ◽  
Rana Hazim Hamoode ◽  
Dalal A. Sattar
Keyword(s):  
Pregnant Women ◽  
First Trimester ◽  
Vital Role ◽  
Review Article ◽  
The Body ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Maternal Immune System ◽  
Disease Occurrence ◽  
Missed Diagnosis

Around 80% of the hyperthyroidism cases of women of childbearing age are inflammatory due to Graves' disease. Production and manifestation of other than gestational and early-onset diabetes may be linked to the hormonal modifications in the maternal immune system during birth. Therefore, in addition to the hormonal influences, the pregnancy test will be affected by various anatomical modifications or alterations seen in the body during pregnancy. For the health of a woman and the start of her pregnancy, thyroid hormones are very significant. These hormones are critical in early development and play a vital role in continuing the fetus's growth since conception. Women with untreated or inadequately controlled hyperthyroidism are at risk of giving birth problems. Future diseases, particularly those with IUGRTH producing so many fetuses. The treatment of hyperthyroid pregnant people is so tricky, and medical staff involvement is needed to ensure that it's monitored and treated in various ways. Pregnant women are prescribed antithyroid medications, and it is the medication of preference for most pregnant women (ATDs). Although both of these medications are transmitted to the fetus by the mother's bloodstream, they are significantly efficient in the treatment of maternal hyperthyroidism. Still, they need caution throughout the second half of pregnancy because of the possibility of fetopathy. Except in the first trimesters from weeks 6 to 10 weeks, the most prevalent adverse effect is abnormalities in the fetal; even with that as a caveat, the incidence of birth defects is high during the first trimester with the help of ATDs. The treatment of hyperthyroidism during pregnancy goes into four issues that are currently of major importance to obstetricians: its aetiology, disease occurrence, proper detection, under treatment, complications, and actual or a missed diagnosis and intervention, and finally, the method of dealing with the problem.

scholarly journals 810 nm Low-intensity laser in the treatment of degenerative articular disease associated with kinesiotherapy and condroprotectors – Case report

2021 ◽  
Vol 10 (6) ◽  
pp. e18710615494
Author(s):  
Raíssa da Costa Furtado ◽  
Antonieta Marques Caldeira Zabeu ◽  
Newton Soares da Silva
Keyword(s):  
Case Report ◽  
Articular Cartilage ◽  
Chronic Disease ◽  
Hip Joint ◽  
Degenerative Joint Disease ◽  
The Body ◽  
Joint Disease ◽  
Low Intensity ◽  
Progressive Degeneration ◽  
Intensity Laser

Degenerative Joint Disease (DJD), also known as Osteoarthritis (OA), is a chronic disease of progressive degeneration for which there is no cure, which can occur in one or more joints in the body, usually caused by overweight of the animal, longevity, instability, incongruence or by injury to the articular cartilage itself. Adult and senile dogs may be affected by this disease as a result of obesity, hormonal disease, natural wear of the joints. In this case, the most affected joint processes are in the pelvic limbs, in the knees and in the hip joint, in the thoracic limbs and in the elbow joints. This work aims to describe the Low Intensity Laser (LIL) efficacy of treatments associated with kinesiotherapy and chondroprotective drugs, performed on a female canine dog affected by this disease in her hip joint and to evaluate this methodology as one of the therapeutic choices more appropriate and less aggressive for the treatment of this disease.

Analysis of Therapeutic Effectiveness of Selected Types of Collagen in Prevention and Treatment of Degenerative Joint Disease

2017 ◽  
Vol 19 (1) ◽  
pp. 9-22
Author(s):  
Wiesław Tomaszewski ◽  
Anna Paradowska
Keyword(s):  
Degenerative Joint Disease ◽  
The Body ◽  
Joint Disease ◽  
Comprehensive Treatment ◽  
Therapeutic Effectiveness ◽  
Collagen Types ◽  
Based Medicine ◽  
New Generation

Loss of collagen is a natural development accompanying aging of the body. It may be additionally accelerated by various conditions, including osteoarthritis (OA). Within the last two decades numerous and diverse studies have been conducted worldwide with the aim of identifying substances containing collagen, producing therapeutic preparations of expected effectiveness in the prevention and therapy of OA that would be safe to use and developing methods of delivering the final product into the body. The authors reviewed and analysed the latest available literature by selecting papers presenting the findings of studies conducted in line with the principles of Evidence-Based Medicine (EBM). The studies have been ordered from in vitro trials (studies on animals in the laboratory setting, use of tissue engineering methods to assess the effect of cartilage transplants, use of different collagen types for development of scaffolds etc.) to in vivo clinical trials. It appears that the findings of the latest multidimensional studies presented below, which confirm the therapeutic effectiveness of new-generation injectable medical collagen preparations, will help these medical products gain their well-deserved position in the comprehensive treatment of osteoarthritis both with respect to their analgesic properties as well as their ability to enable functional recovery and stimulate regeneration of tissues at the molecular level.

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