scholarly journals Efficacy of Moringa oleifera Leaf Extract for the Treatment of Anemia in Girls

Author(s):  
M. B. Shinde ◽  
D. R. Waghchoure ◽  
S. A. Bhutada ◽  
S. B. Dahikar ◽  
R. V. Kshirsagar

The Moringa oleifera has proven to be an ancient medicine for for anemia, skin infections, blackheads, anxiety, and pimples, for intestinal worms, lactation, diabetes and pregnancy. Green leafy vegetables and fruits provide much needed essential micronutrients. Moringa leaves in particular are a rich, inexpensive source of micronutrients. In teenage girls a large number of hormonal changes are witnessed and due to the change in diet which lacks the intake of leafy vegetables and fruits that are essential, a large number of anemic cases are observed. To overcome this problems moringa oleifera leaves extract was formulated. 10 girls of the age group ranging between 17-21 years were selected and their haematological investigation was done. Oral administration of this extract was continued for over a month to these girls. After a month haematological investigation were repeated. Haemoglobin of the moringa extract treated group when compared with the before treatment group were , found out to be increased due to the phytochemical constituents in the extract and also presence of minerals and vitamins.

Author(s):  
Ashraf Albrakati

Tramadol, a broadly in recent years, is an effective analgesic agent for the treatment of moderate to acute pain. Its metabolites are excreted by the kidney which may cause nephrotoxicity. Moringa oleifera leaves are commonly used to provide herbal and plant-derived medicinal products especially in developing nations. The present study was carried out to determine the biochemical and histopathological changes in the kidney of tramadol-treated albino mice and to evaluate the possible protective role of Moringa oleifera leaves against tramadol-induced nephrotoxicity. Twenty adult albino mice were divided into four groups. Control group (group i) received daily intraperitoneal injection of normal saline only, group ii received oral dose of Moringa oleifera leaves extract (20 mg/kg/bw) for three weeks, group iii received daily intraperitoneal dose of tramadol (0.3 mg/kg/bw) for the same period, group iv, received daily oral dose of Moringa oleifera leaves extract, (20 mg/kg/bw) three hours before injecting intraperitoneal dose of tramadol (0.3 mg/kg/bw), for the same period. Blood samples were withdrawn at the end of the experiment for kidney function tests and specimens from the kidney were processed for histological study. No significant differences in the mean values of the kidney function tests were noticed between Moringa oleifera group and control group. However, there was highly significant increase in the mean values of serum, urea and creatinine in tramadol-treated group as compared to the control group. Although tramadol + Moringa oleifera group revealed significant difference in the mean values of urea and creatinine when compared with tramadol-treated group. So, Moringa oleifera leaves extract have been shown to attenuate the renal dysfunction, improve the renal architecture, with nearly normalization of serum urea and creatinine levels which indicate improvement of renal function. In conclusion, in the light of biochemical results and histological findings, co-administration of Moringa oleifera leaves lessened the negative effects of tramadol-induced nephrotoxicity; possibly by its antioxidant action. Further investigation of these promising protective effects of Moringa oleifera leaves against tramadol-induced renal injury may have considerable impact on developing an adjunct therapy aiming to improve the therapeutic index of some nephrotoxic drugs.


2002 ◽  
Vol 16 (2) ◽  
pp. 121-131 ◽  
Author(s):  
Sudesh Jood ◽  
Saroj Bishnoi ◽  
Neelam Khetarpaul

Average daily food intakes of 90 rural pregnant women belonging to arid, semi-arid and wet zones of Haryana State, Northern India have been determined. As a result of questionnaires and interviews, food intake for three consecutive days were collected. Intakes of cereals, pulses, roots and tubers, other vegetables and sugar and jaggery by the respondents were significantly lower than the prescribed Indian Recommended Dietary Intakes (RDI). The consumption of milk and milk products and fats and oils was significantly higher than that of RDI whereas, green leafy vegetables and fruits were the most limited food items. As the diets of rural pregnant women were inadequate with respect to some food groups, which resulted in lower intake of protein, β-carotene and ascorbic acid. Despite their poor intake their weights and heights were not much below the standards. BMI classification projected that only about one fourth of the respondents were underweight. There is pressing need to educate rural pregnant women regarding their increased nutritional requirements.


2019 ◽  
pp. 1-17
Author(s):  
N. N. Umerah ◽  
N. M. Nnam

Background/Objective: Vegetables and fruits play a highly significant role in food security of the underprivileged in both urban and rural settings. The study was designed to determine the nutritional composition of some neglected underutilized fruits and vegetables in Southeast geopolitical zone of Nigeria. Methodology: The commonly occuring underutilized fruits and vegetables were selected for the study. The food crops were harvested and identified at the Herbarium in the Department of Plant Science and Biotechnology, University of Nigeria Nsukka. Twenty underutilized fruits and vegetables each were cleaned and analysed for nutrients composition using standard methods. Data were presented using descriptive statistics, percentage, mean, standard deviation and frequency. Results: The proximate composition of the fruits ranged from 54.34-80.30% moisture, 0.27-6.21% protein, 0-3.08% fat, 0.28-8.58 % fibre, 0.33-11.05% ash and 9.08-36.61% carbohydrate. The ranges for mineral values of the fruits were iron 0.10-9.60 mg, zinc 0.02-10.30 mg, manganese 0.10-6.60 mg and calcium 5.42-46.50 mg.  The vitamin contents of the fruits ranged from beta-carotene traces -5666.67 RE, ascorbic acid 0-48.82 mg and vitamin E 0 -11.99 mg. The proximate composition of the vegetables ranged from moisture 60.45-91.00%, protein 0.02-6.60%, fat 0.02-2.19%, fibre 0.04-5.01%, ash 0.04-4.20% and carbohydrate 10.30-36.61%. The ranges for mineral values of the vegetables were iron 1.40-14.80 mg, zinc trace-9.40 mg, manganese 0.07-4.80 mg and calcium 18.19-400.00 mg. The vitamin levels of the vegetables were beta-carotene 15.20-1933.33 RE, ascorbic acid 2.40-38.40 mg and vitamin E traces - 6.67 mg. Conclusion: The use of these fruits and vegetables should be encouraged particularly in areas where they are not produced through nutrition education in order to promote the food use of these crops.


2016 ◽  
Vol 23 (1) ◽  
Author(s):  
Leila O. Olano

Naturally-made products are now available in the local and international markets. Green leafy vegetables are very rich in phytonutrients that could be utilized in producing value-added products like vegetable jellies. The study considered green leafy vegetables: Malunggay (Moringa oleifera), Kulitis  (Amaranthus spinosus L.), Camote tops (Ipomoea batatas), Alugbati (Basella Rubra Linn),Saluyot (Corchoru solitorius) for the development of vegetable jellies. It specifically determined the sensory acceptability of vegetable jellies in terms of their appearance, aroma, color, texture, consistency, and general acceptability using the single factor experiment in a Completely Randomized Design considering five treatments evaluated by 80 evaluators using score cards for sensory evaluation. The appearance, aroma, texture, consistency and general acceptability of Malunggay jelly was “Liked Very Much” while Saluyot jelly was “Liked Extremely” in terms of color. There were significant differences among the vegetable jellies in the sensory qualities and general acceptability of Malunggay jelly and Saluyot jelly in terms of color. The five vegetable jellies were acceptable. Malunggay jelly had the highest acceptability that was high in ash, crude protein, crude fat, carbohydrates and energy content. Saluyot jelly was high in moisture content, and Alugbati jelly was high in sodium content. Malunggay (Horseradish tree), Alugbati (Malabar nightshade), and Saluyot (Jute leaves) vegetables have potentials for product development as vegetable jellies.


2019 ◽  
Vol 122 (9) ◽  
pp. 1033-1039 ◽  
Author(s):  
Yaqin Zhang ◽  
Jiao Yang ◽  
Ninghua Huang ◽  
Linyan Xiao ◽  
Hong Lin ◽  
...  

AbstractWe aimed to investigate the trends of breast milk lutein concentrations at different times and their relationship with dietary lutein intake during the 12 weeks after delivery. Breast milk samples were collected from thirty-seven mothers at 4, 8 and 12 weeks postpartum. A HPLC detection method was used to measure breast milk lutein concentrations. Dietary intake was assessed using an FFQ, and then dietary lutein intake was calculated. The correlations between dietary lutein intake and breast milk lutein concentrations during lactation were investigated by Pearson’s correlation coefficient. General linear regression models were used to evaluate the optimal regression equation. The mean values of dietary lutein intake at 4, 8 and 12 weeks postpartum were 5·22 (sd 3·60), 7·28 (sd 4·30) and 7·33 (sd 4·24) mg/d, respectively. The mean values of breast milk lutein concentrations at 4, 8 and 12 weeks postpartum were as follows: 46·41 (sd 41·36), 57·96 (sd 40·00) and 62·33 (sd 30·10) μg/l, respectively. Breast milk lutein concentrations were positively associated with dietary lutein intake at 4 weeks postpartum (r 0·527, P < 0·05), which was consistent with the positive correlations observed at 8 and 12 weeks postpartum (r 0·444, P < 0·05; r 0·468, P < 0·05) by the sensitivity analysis. Increased dietary lutein intake can increase the concentration of lutein in the breast milk, and women are recommended to increase their dietary intake of green leafy vegetables and fruits that are rich in lutein during the pregnancy and postpartum periods.


2019 ◽  
pp. 1-12
Author(s):  
N. N. Umerah ◽  
N. M. Nnam

Background/Objective: Vegetables and fruits are important sources of protective substances, which are highly beneficial for the maintenance of good health and prevention of diseases. Phytochemicals are non-nutritive plant chemicals that have protective or disease preventive properties. The study was designed to determine the phytochemicals, In-vitro-bioavailability of beta carotene and anti-nutrient composition of some neglected underutilized fruits and vegetables in Southeast geopolitical zone of Nigeria. Methodology: The frequently occurred underutilized fruits and vegetables were selected for the study. The food crops were harvested and identified at the Herbarium in the Department of Plant Science and Biotechnology, University of Nigeria Nsukka. Twenty underutilized fruits and vegetables each were cleaned and analysed for phytochemicals, In vitro bioavailability of beta carotene and anti-nutrients composition using standard methods. Data were presented using descriptive statistics, percentage, mean, standard deviation and frequency. Results: The result showed that 0 - 40% of beta carotene were bioavailable in the fruits studied.  The antinutrient levels in fruits were cyanide (0.02-3.47 mg), oxalate 1.22-12.38 mg and phytate traces- 12.60 mg. The range of phytochemicals in the fruits were tannins trace-10.40 mg, flavonoids 0-0.10%, saponins trace-0.051 mg, lycopene trace-94.20 mg, and phenol 0-4.01mg. The antinutrient levels in vegetables were cyanide 0.35-13.20 mg, oxalate 2.27-24.69 mg and phytate traces- 2.57 mg.  The result showed that 22- 68.80% of beta carotene were bio available in the vegetables studied. The phytochemicals in the vegetables were tannins 0.10-10.30 mg, flavonoids trace-0.20%, saponins trace-0.10 mg, lycopene trace-31.20 mg and phenol 0.01-3.31 mg. Conclusion: The use of these neglected fruits and vegetables is imperative because of their nutritional and health benefit.


2020 ◽  
Vol 9 (2) ◽  
pp. 101-106
Author(s):  
Haitham Hassen Abd ◽  
Harith Abdulrhman Ahmed ◽  
Thulfiqar Fawwaz Mutar

Abstract Tramadol is a synthetic opioid analgesic used for moderate-to-severe pain structurally related to codeine and morphine, where their analgesic mechanism is a result of opioid and non-opioid mechanisms. This study was designed to evaluate the effects of Moringa oleifera leaves extract (MLE) on tramadol-induced testicular toxicity, sperm changes, testicular damage, and oxidative stress in male rats. Forty male albino rats were divided into four groups and treated for 4 weeks (group 1, as control; group 2, MLE; group 3, tramadol; group 4, MLE + tramadol). The relative body weight, relative testes weight, serum total testosterone, luteinizing hormone, follicle-stimulating hormone, sperm counts, vitality, total sperm motility, catalase, and superoxide dismutase activities were significantly decreased in tramadol-treated group when compared with the control group. In contrast, sperm abnormality, immotile sperm percent, testicular injury, and TBARS concentration in testes were significantly increased in the tramadol-treated group. In addition, histopathological examination for the tramadol-treated group has shown incomplete spermatogenesis, moderate degeneration in some seminiferous tubules with a significant decrease in the number of spermatogenic cells and depletion of Leydig cells. The administration of MLE with tramadol ameliorates the testicular toxicity, injury, sperm count, abnormalities, and oxidative stress induced by tramadol.


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