Bullous dermatosis and systemic lupus erythematosus in a 15-year-old boy

1979 ◽  
Vol 115 (9) ◽  
pp. 1094-1097 ◽  
Author(s):  
R. A. Jacoby
2020 ◽  
Vol 2 (4) ◽  
pp. 388-390
Author(s):  
Salem Bouomrani ◽  
◽  
Sihem Riahi ◽  
Marwa Ben Houchet ◽  
◽  
...  

Vesiculobullous lesions can be developed by less than 5% of patients with systemic lupus erythematosus (SLE). Among these lesions, bullous systemic lupus erythematosus (BSLE) is one of the rarest and most challenging cutaneous presentations of the disease. Its frequency in the largest series of 5149 patients with cutaneous lupus was 0.19%, and the majority of cases are reported as sporadic observation or small series not exceeding ten cases. We report the original observation of BSLE revealing SLE in 32-year-old Tunisian Woman. This atypical presentation of cutaneous lupus deserves to be known by clinicians and discussed in front of any bullous dermatosis, particularly in young woman.


2007 ◽  
Vol 27 (3) ◽  
pp. 391-393 ◽  
Author(s):  
Gabriel J. Tobón ◽  
Carlos E. Toro ◽  
Juan-Carlos Bravo ◽  
Carlos A. Cañas

Author(s):  
Francis R. Comerford ◽  
Alan S. Cohen

Mice of the inbred NZB strain develop a spontaneous disease characterized by autoimmune hemolytic anemia, positive lupus erythematosus cell tests and antinuclear antibodies and nephritis. This disease is analogous to human systemic lupus erythematosus. In ultrastructural studies of the glomerular lesion in NZB mice, intraglomerular dense deposits in mesangial, subepithelial and subendothelial locations were described. In common with the findings in many examples of human and experimental nephritis, including many cases of human lupus nephritis, these deposits were amorphous or slightly granular in appearance with no definable substructure.We have recently observed structured deposits in the glomeruli of NZB mice. They were uncommon and were found in older animals with severe glomerular lesions by morphologic criteria. They were seen most commonly as extracellular elements in subendothelial and mesangial regions. The deposits ranged up to 3 microns in greatest dimension and were often adjacent to deposits of lipid-like round particles of 30 to 250 millimicrons in diameter and with amorphous dense deposits.


2000 ◽  
Vol 6 (7) ◽  
pp. 821-825 ◽  
Author(s):  
ELIZABETH LERITZ ◽  
JASON BRANDT ◽  
MELISSA MINOR ◽  
FRANCES REIS-JENSEN ◽  
MICHELLE PETRI

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