A Prussian Blue-Based Core-Shell Hollow-Structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH-Responsive Longitudinal Relaxivity

2015 ◽  
Vol 27 (41) ◽  
pp. 6382-6389 ◽  
Author(s):  
Xiaojun Cai ◽  
Wei Gao ◽  
Ming Ma ◽  
Meiying Wu ◽  
Linlin Zhang ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Core Shell ◽  
Ph Responsive ◽  
Theranostic Agent ◽  
Longitudinal Relaxivity

scholarly journals Nanoparticles: A Prussian Blue-Based Core-Shell Hollow-Structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH-Responsive Longitudinal Relaxivity (Adv. Mater. 41/2015)

2015 ◽  
Vol 27 (41) ◽  
pp. 6536-6536 ◽  
Author(s):  
Xiaojun Cai ◽  
Wei Gao ◽  
Ming Ma ◽  
Meiying Wu ◽  
Linlin Zhang ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Core Shell ◽  
Ph Responsive ◽  
Theranostic Agent ◽  
Longitudinal Relaxivity

Prussian blue-coated lanthanide-doped core/shell/shell nanocrystals for NIR-II image-guided photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (45) ◽  
pp. 22079-22088 ◽  
Author(s):  
Xin Wang ◽  
Hui Li ◽  
Feng Li ◽  
Xiaojun Han ◽  
Guanying Chen
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Core Shell ◽  
Image Guided ◽  
Theranostic Agent

A lanthanide-based theranostic agent for image-guided photothermal therapy.

scholarly journals In situ formation of pH-responsive Prussian blue for photoacoustic imaging and photothermal therapy of cancer

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18270-18276 ◽  
Author(s):  
Ming Cheng ◽  
Wei Peng ◽  
Peng Hua ◽  
Zhengrong Chen ◽  
Jia Sheng ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ph Responsive ◽  
Background Signal ◽  
Normal Tissues ◽  
Theranostic Agent ◽  
In Situ Formation

Dual pH-responsive theranostic agent reduces the background signal in photoacoustic imaging and non-specific heating of normal tissues in photothermal therapy.

Highly efficient sunitinib release from pH-responsive mHPMC@Chitosan core-shell nanoparticles

2021 ◽  
Vol 258 ◽  
pp. 117719
Author(s):  
Hessam Jafari ◽  
Gholam Reza Mahdavinia ◽  
Bagher Kazemi ◽  
Hermann Ehrlich ◽  
Yvonne Joseph ◽  
...  
Keyword(s):  
Core Shell ◽  
Ph Responsive ◽  
Shell Nanoparticles ◽  
Highly Efficient ◽  
Core Shell Nanoparticles

scholarly journals Bacteriophage Encapsulation in pH-Responsive Core-Shell Capsules as an Animal Feed Additive

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1131
Author(s):  
Kerry Richards ◽  
Danish J. Malik
Keyword(s):  
Animal Feed ◽  
Feed Additive ◽  
Core Shell ◽  
Ph Responsive ◽  
Zoonotic Infections ◽  
The Core ◽  
Extrusion Processing ◽  
Food Borne ◽  
Wet Heat ◽  
Food Borne Infections

Increasing antibiotic resistance in bacteria that cause zoonotic infections is a major problem for farmers rearing animals for food as well as for consumers who eat the contaminated meat resulting in food-borne infections. Bacteriophages incorporated in animal feed may help reduce carriage and infections in animals including chickens and pigs. There are, however, unmet challenges in protecting phages from processing stresses e.g., during animal feed pelleting operations and during transit of phages through the acidic gastric environment. Core-shell capsules were produced using a concentric nozzle and commercially available encapsulation equipment to fabricate capsules with phages formulated in an oil-in-water microemulsion in the core. pH-responsive capsules released the encapsulated phage cargo within 10–30 min triggered by changes in local environmental pH typically found in the lower gastrointestinal (GI) tract of animals. Acid stability of phages exposed to pH values as low as pH 1 was demonstrated. Encapsulated phages were able to withstand exposure to 95 °C wet heat thermal stress for up to 120 s, conditions typically encountered during feed pellet extrusion processing. Free phages were inactivated within 15 s under these conditions. The present study demonstrates that encapsulation of bacteriophages in core-shell pH-responsive capsules with water-in-oil emulsified phages in the core significantly improves phage viability upon exposure to processing and environmental stresses that require consideration during production of animal feed and application in animals for biocontrol. The results from this study should help guide future development of phage formulations suitable for use in animal feed for animal biocontrol applications.

scholarly journals Removal of Cd(II) from Micro-Polluted Water by Magnetic Core-Shell Fe3O4@Prussian Blue

Molecules ◽  
2021 ◽  
Vol 26 (9) ◽  
pp. 2497
Author(s):  
Xinxin Long ◽  
Huanyu Chen ◽  
Tijun Huang ◽  
Yajing Zhang ◽  
Yifeng Lu ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Co Adsorption ◽  
Magnetic Core ◽  
Diameter Distribution ◽  
Polluted Water ◽  
Core Shell ◽  
Freundlich Model ◽  
Rate Limiting Step ◽  
Rate Limiting

A novel core-shell magnetic Prussian blue-coated Fe3O4 composites (Fe3O4@PB) were designed and synthesized by in-situ replication and controlled etching of iron oxide (Fe3O4) to eliminate Cd (II) from micro-polluted water. The core-shell structure was confirmed by TEM, and the composites were characterized by XRD and FTIR. The pore diameter distribution from BET measurement revealed the micropore-dominated structure of Fe3O4@PB. The effects of adsorbents dosage, pH, and co-existing ions were investigated. Batch results revealed that the Cd (II) adsorption was very fast initially and reached equilibrium after 4 h. A pH of 6 was favorable for Cd (II) adsorption on Fe3O4@PB. The adsorption rate reached 98.78% at an initial Cd (II) concentration of 100 μg/L. The adsorption kinetics indicated that the pseudo-first-order and Elovich models could best describe the Cd (II) adsorption onto Fe3O4@PB, indicating that the sorption of Cd (II) ions on the binding sites of Fe3O4@PB was the main rate-limiting step of adsorption. The adsorption isotherm well fitted the Freundlich model with a maximum capacity of 9.25 mg·g−1 of Cd (II). The adsorption of Cd (II) on the Fe3O4@PB was affected by co-existing ions, including Cu (II), Ni (II), and Zn (II), due to the competitive effect of the co-adsorption of Cd (II) with other co-existing ions.

Fabrication of pH Responsive Core-Shell Nanosystem with Low-Temperature Photothermal Therapy Effect for Treating Bacterial Biofilm Infection

2021 ◽  
Author(s):  
Dan Peng ◽  
Genhua Liu ◽  
Ye He ◽  
Pengfei Gao ◽  
Shuangquan Gou ◽  
...  
Keyword(s):  
Low Temperature ◽  
Photothermal Therapy ◽  
Normal Tissue ◽  
Bacterial Biofilm ◽  
Alternative Strategy ◽  
Viable Alternative ◽  
Core Shell ◽  
Ph Responsive ◽  
Therapy Effect ◽  
Biofilm Infection

Recently, photothermal therapy (PTT) has been recognized as a viable alternative strategy against bacterial biofilm infection. However, hyperthermia required for PTT to ablate biofilm usually induced damage of normal tissue/organ...

A pH-responsive amphiphilic chitosan–pyranine core–shell nanoparticle for controlled drug delivery, imaging and intracellular pH measurement

2014 ◽  
Vol 2 (38) ◽  
pp. 6580-6589 ◽  
Author(s):  
Hao-Syun Chou ◽  
Meng-Hsuan Hsiao ◽  
Wei-Yang Hung ◽  
Tin-Yo Yen ◽  
Hui-Yi Lin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph ◽  
Controlled Drug Delivery ◽  
Ph Measurement ◽  
Core Shell ◽  
Ph Responsive ◽  
Cellular Resolution ◽  
New Type

A new type of CHC–PY core–shell nanoparticle provides multiple functionality, where a synergistic performance of nanotherapeutics, imaging and even diagnosis at a cellular resolution can be achieved simultaneously.

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