Elevated urate does not alter bone turnover markers. Randomized controlled trial of inosine supplementation in post‐menopausal women

2021 ◽  
Author(s):  
Nicola Dalbeth ◽  
Anne Horne ◽  
Borislav Mihov ◽  
Angela Stewart ◽  
Gregory D Gamble ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Menopausal Women ◽  
Turnover Markers ◽  
Post Menopausal

scholarly journals Bone Turnover Markers After Standard and Distal Roux-en-Y Gastric Bypass: Results from a Randomized Controlled Trial

2019 ◽  
Vol 29 (9) ◽  
pp. 2886-2895 ◽  
Author(s):  
Marius Svanevik ◽  
Hilde Risstad ◽  
Dag Hofsø ◽  
Ingvild K Blom-Høgestøl ◽  
Jon A. Kristinsson ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Gastric Bypass ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Turnover Markers

scholarly journals Soy Reduces Bone Turnover Markers in Women During Early Menopause: A Randomized Controlled Trial

2016 ◽  
Vol 32 (1) ◽  
pp. 157-164 ◽  
Author(s):  
Thozhukat Sathyapalan ◽  
Mo Aye ◽  
Alan S Rigby ◽  
William D Fraser ◽  
Natalie J Thatcher ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Controlled Trial ◽  
Early Menopause ◽  
Randomized Controlled ◽  
Turnover Markers

scholarly journals Effects of Vitamin D Supplementation on Bone Turnover Markers: A Randomized Controlled Trial

Nutrients ◽  
2017 ◽  
Vol 9 (5) ◽  
pp. 432 ◽  
Author(s):  
Verena Schwetz ◽  
Christian Trummer ◽  
Marlene Pandis ◽  
Martin Grübler ◽  
Nicolas Verheyen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Randomized Controlled ◽  
Turnover Markers

scholarly journals Equol effects on AGE skin products, visceral fat and climacteric symptoms in post-menopausal women: A randomized controlled trial

2021 ◽  
Author(s):  
Remi Yoshikata ◽  
Khin Zay Yar Myint ◽  
Hiroaki Ohta ◽  
Yoko Ishigaki
Keyword(s):  
Randomized Controlled Trial ◽  
Visceral Fat ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Climacteric Symptoms ◽  
Post Intervention ◽  
Randomized Controlled ◽  
Menopausal Women ◽  
Post Menopausal

Abstract Introduction: Equol, an isoflavone derivative whose chemical structure is similar to estrogen, is considered as a potentially effective agent for relieving climacteric symptoms, for the prevention of the lifestyle-related diseases, and for aging care in post-menopausal women. We investigated the effect of an equol-containing supplement on metabolism and aging, and climacteric symptoms, with respect to internally-produced equol in post-menopausal women.Methods: A single center, randomized controlled trial (registration number: UMIN000030975) on 57 post-menopausal Japanese women (mean age: 56±5.37 years), was conducted. Twenty-seven women received the equol supplement, while the remaining received Control. Metabolic and aging-related biomarkers were compared before and after the 3-month intervention. Climacteric symptoms were assessed every month using a validated self-administered questionnaire in Japanese post-menopausal women. Results: Three months post intervention, the treatment group showed significant improvement in climacteric symptoms, when compared to the Control group (81% vs. 53% respectively, p=0.045). We did not observe any beneficial effect on metabolic and aging-related biomarkers in the intervention group. However, in certain populations significant improvement in skin auto-fluorescence, which is a measurement of AGE skin products, and visceral fat area was observed, especially among equol producers. Conclusion: Women receiving equol supplement showed improved climacteric symptoms. This study offered a new hypothesis that there may be a synergy between supplemented equol and endogenously-produced equol to improve skin aging and visceral fat in certain populations.

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