Risk of corticosteroid treatment and hospitalization after checkpoint inhibitor and radiation therapy in patients with cancer

Cancer ◽  
2021 ◽  
Author(s):  
Kate E. Lee ◽  
David A. Bender ◽  
Lawrence D. Koutcher ◽  
Brigham Hyde ◽  
Chin Hur ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Checkpoint Inhibitor ◽  
Corticosteroid Treatment ◽  
Patients With Cancer

Abstract LB037:89ZED88082A PET imaging to visualize CD8+T cells in patients with cancer treated with immune checkpoint inhibitor

2021 ◽  
Author(s):  
Laura Kist de Ruijter ◽  
Pim P. van de Donk ◽  
Jahlisa S. Hooiveld-Noeken ◽  
Danique Giesen ◽  
Alexander Ungewickell ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Pet Imaging ◽  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitor ◽  
Checkpoint Inhibitor ◽  
Patients With Cancer

scholarly journals Insights and Perspectives in the Clinical and Operational Management of Cancer-Related Anemia

2010 ◽  
Vol 8 (Suppl_7) ◽  
pp. S-38-S-55 ◽  
Author(s):  
Jennifer M. Hinkel ◽  
Edward C. Li ◽  
Stephen L. Sherman
Keyword(s):  
Quality Of Life ◽  
Radiation Therapy ◽  
Surgical Interventions ◽  
Patients With Cancer ◽  
Cancer Related Fatigue ◽  
Operational Management ◽  
Life Issues ◽  
Economic Perspectives ◽  
Cancer Related Anemia

Management of anemia in patients with cancer presents challenges from clinical, operational, and economic perspectives. Clinically, anemia in these patients may result from treatment (chemotherapy, radiation therapy, or surgical interventions) or from the malignancy itself. Anemia not only contributes to cancer-related fatigue and other quality of life issues, but also affects prognosis. From the operational perspective, a patient with cancer who is also anemic may consume more laboratory, pharmacy, and clinical resources than other patients with cancer.

Toxicity in combination immune checkpoint inhibitor and radiation therapy: A systematic review and meta-analysis

2020 ◽  
Vol 151 ◽  
pp. 141-148 ◽  
Author(s):  
Congzhou M. Sha ◽  
Eric J. Lehrer ◽  
Clara Hwang ◽  
Daniel M. Trifiletti ◽  
Heath B. Mackley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Radiation Therapy ◽  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitor ◽  
Checkpoint Inhibitor ◽  
Meta Analysis

scholarly journals Understanding American Indian Perceptions Toward Radiation Therapy

2020 ◽  
Vol 27 (3) ◽  
pp. 107327482094599
Author(s):  
Samir H. Patel ◽  
Sasha Ebrahimi ◽  
Donald W. Northfelt ◽  
Timothy E. Mathews ◽  
Farhia M. Omar ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Adverse Effects ◽  
American Indian ◽  
Alaska Native ◽  
Medical Center ◽  
Transportation Cost ◽  
Survey Study ◽  
Cost Of Treatment ◽  
Patients With Cancer ◽  
To Receive

Many American Indian (AI) and Alaska native (AN) patients do not complete guideline-concordant cancer care for the 4 most common cancers. Our aim was to better understand AI/AN attitudes toward radiation therapy (RT). Patients eligible for this survey study were AI/AN patients with cancer at the Phoenix Indian Medical Center who either received previous RT or were recommended to receive RT. An 18-item questionnaire was administered to each of the 50 participants from October 1, 2018, through February 15, 2019. Willingness to travel for RT was compared to respondent characteristics, concerns regarding RT, and obstacles to obtain RT. Duration of RT was important to 78% of patients: 24% would consider traveling 25 miles or more for a standard course, and 48% would travel that distance for a shorter course ( P < .001). The top-ranked barriers to RT were transportation, cost of treatment, and insurance compatibility. The top-ranked concerns about RT were adverse effects, cost of treatment, and fear of RT. Concerns about adverse effects were associated with the radiation team’s inability to explain the treatment ( P = .05). Transportation concerns were significantly associated with accessibility ( P = .02), communication with the RT team ( P = .02), and fear of RT ( P = .04). AI/AN patients are concerned about the adverse effects of RT and the logistics of treatment, particularly costs, transportation, and insurance compatibility. Use of culturally specific education and hypofractionation regimens may increase acceptance of RT for AI/AN patients with cancer, and this hypothesis will be tested in a future educational intervention-based study.

scholarly journals Variation in the Cost of Radiation Therapy Among Medicare Patients With Cancer

2015 ◽  
Vol 11 (5) ◽  
pp. 403-409 ◽  
Author(s):  
Anthony J. Paravati ◽  
Isabel J. Boero ◽  
Daniel P. Triplett ◽  
Lindsay Hwang ◽  
Rayna K. Matsuno ◽  
...  
Keyword(s):  
Health Care ◽  
Radiation Therapy ◽  
Health Care Expenditure ◽  
Patients With Cancer ◽  
Medicare Patients ◽  
The Individual ◽  
The Cost

Factors unrelated to the individual patient accounted for the majority of variation in the cost of radiation therapy, suggesting potential inefficiency in health care expenditure.

scholarly journals Differences in Sleep Disturbance Parameters Between Oncology Outpatients and Their Family Caregivers

2011 ◽  
Vol 29 (8) ◽  
pp. 1001-1006 ◽  
Author(s):  
Sara Carney ◽  
Theresa Koetters ◽  
Maria Cho ◽  
Claudia West ◽  
Steven M. Paul ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Sleep Disturbance ◽  
Family Caregivers ◽  
Family Caregiver ◽  
Quality Index ◽  
Pittsburgh Sleep Quality Index ◽  
Objective Measures ◽  
Systematic Assessment ◽  
Patients With Cancer ◽  
Clinically Significant

Purpose This study compared the occurrence rates for and severity ratings of sleep disturbance in patient-family caregiver (FC) dyads. Patients and Methods In total, 102 dyads were recruited from two radiation therapy (RT) departments. Patients and their FCs completed the Pittsburgh Sleep Quality Index (PSQI) and the General Sleep Disturbance Scale (GSDS) and wore wrist actigraphs to obtain subjective and objective measures of the occurrence and severity of sleep disturbance at the initiation of RT. Match paired t tests were used to evaluate for dyadic differences. Results No differences were found in the occurrence of clinically significant levels of sleep disturbance between patients and their FCs that ranged between 40% and 50% using subjective and objective measures. Few differences were found in the severity of any of the sleep-wake parameters between patients and FCs using both the subjective and objective measures of sleep disturbance. Conclusion The findings from this study suggest that patients with cancer and their FCs experience similar levels of sleep disturbance and that both groups could benefit from interventions that aim to promote restful sleep. In addition to routine and systematic assessment of sleep disturbance by oncology clinicians, interventions are needed that take into account the specific needs of the patient and the FC as well as the potential for partners' sleep patterns to influence one another.

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