A study of postmortem autolysis in the human organ of corti

1985 ◽  
Vol 237 (3) ◽  
pp. 333-342 ◽  
Author(s):  
Joseph B. Nadol ◽  
Barbara Burgess
Keyword(s):  
Organ Of Corti ◽  
Human Organ ◽  
Postmortem Autolysis

Nerve Fibers in the Human Organ of Corti

1976 ◽  
Vol 82 (1-6) ◽  
pp. 317-324 ◽  
Author(s):  
Y. Nomura
Keyword(s):  
Organ Of Corti ◽  
Nerve Fibers ◽  
Human Organ

Scanning Electron Microscopic Study of the Organ of Corti in Normal and Sound-Damaged Guinea Pigs

1976 ◽  
Vol 85 (4_suppl) ◽  
pp. 1-3 ◽  
Author(s):  
Eduard R. Soudijn
Keyword(s):  
Guinea Pigs ◽  
High Speed ◽  
Organ Of Corti ◽  
Tectorial Membrane ◽  
Electron Microscopic ◽  
Human Organ ◽  
Scanning Electron Microscopic Study ◽  
Different Types ◽  
Temporal Bones ◽  
Scanning Electron

A method was evolved by which the organ of Corti could be examined in its entirety with the scanning electron microscope, the organ meanwhile retaining its spiral form. This made it possible to assess traumatic effects on the cochlea and qualify lesions in terms of extent, localization and pattern. It was also found possible eventually to cut the same specimen into sections for cellular and subcellular studies. The number of guinea pigs examined totalled 91, divided into three groups. The first group was used to study the anatomy of the organ of Corti with special reference to normal variations and artifacts. Unmistakable indications were found that the longest stereocilia of the inner hair cells are linked to the tectorial membrane. The animals of the second group were exposed to pure tones of high intensity, whereupon, lesions of the organ of Corti were described according to intensity, time, and frequency. Three different types of otologic drills were used to perform mastoidectomies on temporal bones and on the cadaver. The noise produced was analyzed as to intensity and frequency range. It was found that the drill with the lowest rpm (and highest torque) produced the highest noise intensities, at levels which can be traumatic to the human organ of hearing. The animals of the third group were exposed to the amplified noise produced by otologic drills of three different types. The resulting lesions in the organ of Corti were examined by the method described for scanning electron microscopy and compared. In spite of the wide variation in individual lesions, patterns of degeneration of three different types could be distinguished. The high-speed and the very-high-speed drill inflicted less damage on the organ of Corti than the low-speed drill. It is therefore advised to refrain from using the latter drill in prolonged operations.

Ultrastructure of the normal human organ of Corti. New anatomical findings in surgical specimens

2005 ◽  
Vol 125 (5) ◽  
pp. 534-539 ◽  
Author(s):  
Rudolf Glueckert ◽  
Kristian Pfaller ◽  
Anders Kinnefors ◽  
Helge Rask-Andersen ◽  
Anneliese Schrott-Fischer
Keyword(s):  
Organ Of Corti ◽  
Human Organ ◽  
Normal Human

Membrane specializations in the human organ of corti

1988 ◽  
Vol 106 (1-2) ◽  
pp. 19-28 ◽  
Author(s):  
Dan Bagger-sjöbäck ◽  
Berit Engström ◽  
Maria Hillerdal
Keyword(s):  
Organ Of Corti ◽  
Human Organ

scholarly journals Scanning Electron Microscopy of the Human Organ of Corti

1983 ◽  
Vol 76 (4) ◽  
pp. 269-278 ◽  
Author(s):  
A Wright
Keyword(s):  
Hair Cells ◽  
Organ Of Corti ◽  
Outer Hair Cells ◽  
Sensory Cells ◽  
Surface Appearance ◽  
Human Organ ◽  
Human Cochlea ◽  
Temporal Bones ◽  
Subsequent Staining ◽  
Scanning Electron

The human cochlea has been preserved from post-mortem autolysis by perfusion with a fixative shortly after death. Subsequent staining with osmium permits dissection of this structure from the temporal bone. (Temporal bones were obtained from eight patients). When prepared for examination in the scanning electron microscope, the auditory sensory cells are found to be located in the band-like organ of Corti which extends the length of the cochlea. The sensory cells have a cluster of stereocilia projecting from their free upper surface and because of this are called hair cells. The hair cells are divided into two separate groups: a single row of inner hair cells, which show little variation in their surface appearance along the length of the cochlea, and three or four rows of outer hair cells whose cilia change in conformation and increase in length along the cochlea.

Comparative Study of Age-Related Cochlear Hair Cell Loss

1986 ◽  
Vol 95 (5) ◽  
pp. 510-513 ◽  
Author(s):  
Vijay S. Dayal ◽  
Tapan K. Bhattacharyya
Keyword(s):  
Hair Cell ◽  
Organ Of Corti ◽  
Surface Preparation ◽  
Cell Loss ◽  
Squirrel Monkeys ◽  
Hair Cell Loss ◽  
Human Organ ◽  
Cochlear Hair Cell ◽  
Histological Damage ◽  
Age Related

Age-related hair cell loss has been studied in squirrel monkeys using surface preparation of the organ of Corti. Increasing hair cell loss starting at the apex is seen as a function of age. This finding is discussed in the light of our studies in guinea pigs, chinchillas, and rabbits. Reviewed with other human and experimental data, it would appear that many species of animals have age-related histological damage similar to that seen in the human organ of Corti.

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