A change in social activity affect cognitive function in middle-aged and older Koreans: analysis of a Korean longitudinal study on aging (2006-2012)

2016 ◽  
Vol 31 (8) ◽  
pp. 912-919 ◽  
Author(s):  
Young Choi ◽  
Sohee Park ◽  
Kyoung Hee Cho ◽  
Sung-Youn Chun ◽  
Eun-Cheol Park
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sarah Soyeon Oh ◽  
Eunhee Cho ◽  
Bada Kang

AbstractRecent findings suggest that social disengagement in later life may result in cognitive decline and increase risk of Alzheimer’s and related dementias. However, little is known regarding the gender-specific longitudinal association between social engagement and cognition among middle-aged and older adults. Using data from a nationally representative sample of 2707 men and 5196 women from the Korean longitudinal study of aging, we examined the gender-specific association between social activity and cognitive function. Results from the generalized estimating equation model showed that compared to individuals with consistent social engagement (religious, senior center, sport, reunion, voluntary, political), individuals with inconsistent engagement had lower cognitive function. Transitioning from engagement to non-engagement was associated with lower cognitive function among men only. Not being part of a senior center was associated with decreased cognitive function among both genders, while not being part of a religious group was significant for women only. While marital status was a significant predictor of cognitive ability for women, depression was a significant predictor for men. These findings have implications for policy-makers as interventions targeting improved cognitive function among middle-aged and older adults may be more effective when gender-specific predictors are taken into consideration.


2018 ◽  
Vol 28 (2) ◽  
pp. 95-101.e1 ◽  
Author(s):  
Unni Dokkedal ◽  
Mette Wod ◽  
Mikael Thinggaard ◽  
Tom Giedsing Hansen ◽  
Lars Simon Rasmussen ◽  
...  

Assessment ◽  
2017 ◽  
Vol 26 (8) ◽  
pp. 1582-1593 ◽  
Author(s):  
Zhiyong Huang ◽  
Jürgen Maurer

Memory self-ratings are often used in primary care practice and social surveys due to its relative ease of administration. Yet their usefulness to accurately measure individuals’ memory-related cognitive function is largely unknown. This article assesses the construct validity of self-rated memory for measuring memory-related cognitive function among middle-aged and older adults (45+ years) in China using a national sample ( N = 13,690) from the China Health and Retirement Longitudinal Study. We first compare self-rated memory with a number of well-established memory tests and then investigate the role of sociodemographic factors in determining self-reports conditional on memory test performance. We find that self-rated memory is only weakly correlated with memory test performance and yields low sensitivity and specificity in detecting individuals with relatively poor memory test performance. We also find evidence for substantial differential item functioning across sociodemographic groups. Our results, therefore, caution against the use of simple self-rated memory measures for memory assessments in primary care or survey research.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Tingting Qin ◽  
Mingming Yan ◽  
Zhen Fu ◽  
Yating Song ◽  
Wanrong Lu ◽  
...  

Abstract Background Our objective was to characterize the relationship of anemia and hemoglobin concentrations with cross-sectional cognitive functions and changes in cognitive functions over 2 years in a large sample of Chinese middle aged and elderly. Methods Ten thousand nine hundred eighteen adults aged 45 years or older participating in the China Health and Retirement Longitudinal Study (CHARLS) were used for cross-sectional analyses and 9324 were used for longitudinal analysis. Cognitive functions were assessed by memory recall (episodic memory), mental status (TICS), and global cognitive function at baseline survey (Visit 1) and first follow-up survey (Visit 2). The lower the cognitive test score, the worse the cognitive function. Anemia was defined as hemoglobin concentrations lower than 13 g/dl for men and lower than 12 g/dl for women. Adjusted multivariate regression analyses were used to explore the relationships of different cognitive domains with anemia and hemoglobin concentration. Results Overall, the prevalence of anemia was 12.86% and the mean hemoglobin concentration was 14.37 ± 2.20 g/dl. After adjusting for socio-demographic and health-related covariates, the cross-sectional association between anemia and global cognitive function [β (95%CI) = − 0.49(− 0.69~ − 0.29)], episodic memory [β (95%CI) = − 0.14(− 0.23~ − 0.05)], and TICS [β (95%CI) = − 0.23(− 0.38~ − 0.08)] were significant and did not differ by gender. The hemoglobin concentration was also associated with global cognitive function among the whole sample (P < 0.05 for all). The longitudinal analyses showed global cognitive function and episodic memory were associated with anemia independent of covariates (P < 0.05 for all). Sensitivity analyses further provided significant results showing the association between anemia and cognition decline (P < 0.05). Conclusion There was a cross-sectional and longitudinal association between anemia and accelerated decline in cognitive functions in Chinese middle-aged and elderly. This suggests that anemia and low hemoglobin concentrations are independent risk factors of cognitive decline.


2020 ◽  
Author(s):  
Frank Moriarty ◽  
George M Savva ◽  
Carlota M Grossi ◽  
Kathleen Bennett ◽  
Chris Fox ◽  
...  

Aim To estimate the association between patterns of anticholinergic, benzodiazepine, and Z-drug medication use and change in cognitive function in middle-aged and older adults. Method This prospective cohort study used data from the first three waves of The Irish Longitudinal Study on Ageing (TILDA), including community-dwelling adults aged ≥50 years followed for up to four years (n=7,027). Cognitive function was assessed using the Mini Mental State Examination, animal naming test, and word recall tests. Regular medication use was self-reported at baseline and follow-up interviews at two and four years. Pharmacy dispensing claims for a subset (n=2,905) allowed assessment of medication use between interviews and cumulative dosage. Medication use at consecutive waves of TILDA was analysed in relation to change in cognitive function between waves. Results Strongly anticholinergic medications (Anticholinergic Cognitive Burden scale 3), benzodiazepines, and Z-drugs were reported by 7.3%, 5.8% and 5.1% of participants respectively at any time during the study. Adjusting for potential confounders, new anticholinergic use between interviews was associated with change in recall score (-1.09, 95% confidence interval -1.64, -0.53) over 2 years compared to non-use, but not with MMSE (0.07; 95%CI -0.21, 0.34) or animal naming (-0.70; -1.43, 0.03). The pharmacy claims analysis was consistent with this finding. Other hypothesised associations were not supported. Discussion Except for new use of anticholinergic medications, no other findings supported a risk of cognitive decline over 2-year periods in this middle-aged and older cohort. Patients and prescribers should weigh this potential risk against potential benefits of commencing anticholinergic medications.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S350-S350
Author(s):  
Nan Lu ◽  
Bei Wu ◽  
Yaolin Pei

Abstract While empirical evidence shows that cognitive function affects oral health and vice versa, there is a lack of empirical evidence to test the reciprocal relationship between these two indicators. This study aimed to examine this relationship among middle-aged and older adults in China. Data were derived from the 2011 and 2015 waves of the China Health and Retirement Longitudinal study. A two-wave cross-lag analysis was adopted to test the hypothesized model. Cognitive function in 2011 was found to be a significant predictor of complete tooth loss in 2015. Furthermore, complete tooth loss in 2011 was found to be a significant predictor of cognitive cognition in 2015. This finding demonstrates the reciprocal relationship between cognitive function and oral health. This study highlights the importance of improving both cognitive health and oral health for middle-aged and older adults. Policy and intervention implications are discussed.


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