Five New Oleanane Triterpenoid Saponins from the Aerial Parts ofElsholtzia bodinieri

Chemical constituents of the dried aerial parts of Euphorbia nematocypha were investigated. A new oleanane triterpenoid, trans, trans-2′,4′-hexadienedioicacid-1′-β-amyrin ester (1), together with, β-amyrin (2), β-amyrin acetate (3), betulinic acid (4), ellagic acid (5), oleanolic acid (6), β-sitosterol (7), kaempferol (8), quercetin (9), lupeol (10) and pseudo-taraxasterol (11) were isolated from the methylene chloride extract. Their structures were elucidated on the basis of extensive spectroscopic (1D- & 2D-NMR) and ESI-MS analysis and comparison with data reported in the literature. The new isolated triterpenoid showed moderate cytotoxic activities against HeLa and MCF-7cell lines.

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Identification and quantification of oleanane triterpenoid saponins and potential analgesic and anti-inflammatory activities from the roots and rhizomes of Panax stipuleanatus

Journal of Ginseng Research ◽

10.1016/j.jgr.2020.05.002 ◽

2020 ◽

Cited By ~ 1

Author(s):

Pan-Pan Shu ◽

Lu-Xi Li ◽

Qin-Min He ◽

Jun Pan ◽

Xiao-Lei Li ◽

...

Keyword(s):

Triterpenoid Saponins ◽

Anti Inflammatory ◽

Oleanane Triterpenoid ◽

Identification And Quantification

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Dammarane triterpenoid saponins from Bacopa monnieri

Canadian Journal of Chemistry ◽

10.1139/v09-111 ◽

2009 ◽

Vol 87 (9) ◽

pp. 1230-1234 ◽

Cited By ~ 10

Author(s):

Pamita Bhandari ◽

Neeraj Kumar ◽

Bikram Singh ◽

Inderjeet Kaur

Keyword(s):

Medicinal Plant ◽

2D Nmr ◽

Bacopa Monnieri ◽

Spectroscopic Methods ◽

Triterpenoid Saponins ◽

Enhancing Effect ◽

Indian Medicinal Plant ◽

Aerial Parts ◽

Memory Enhancer ◽

Memory Enhancing

Bacopa monnieri is a well-known Ayurvedic Indian medicinal plant traditionally used as a memory enhancer. Its memory-enhancing effect is mainly attributed to dammarane triterpenoid saponins. In the present study, two new dammarane-type triterpenoid saponins, bacopaside-XI (1) and bacopaside-XII (2), together with known compounds, bacopaside IV, bacopaside V, and apigenin, were isolated from the aerial parts of the B. monnieri . The structures of the new saponins were elucidated as 3-O-[α-L-arabinofuranosyl(1→3)]-6-O-sulfonyl-β-D-glucopyranosyl pseudojujubogenin (1) and 3-O-{β-D-glucopyranosyl(1→3)[α-L-arabinofuranosyl(1→2)]-β-D-glucopyranosyl}-20-O-α-L-arabinopyranosyl pseudojujubogenin (2) on the basis of extensive investigations of 1D and 2D NMR (HMQC and HMBC), ESI-QTOF-MS/MS spectroscopic methods, and chemical evidences.

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